Trifluoroacetophenone derivatives as amino acid selective ionophores for the potentiometric determination of phenylalanine

Shin Ichi Sasaki; Akio Hashizume; Daniel Citterio; Eiji Fujii; Koji Suzuki

doi:10.1002/1521-3773(20020816)41:16<3005::AID-ANIE3005>3.0.CO;2-F

Trifluoroacetophenone derivatives as amino acid selective ionophores for the potentiometric determination of phenylalanine

Shin Ichi Sasaki, Akio Hashizume, Daniel Citterio, Eiji Fujii, Koji Suzuki

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Selective sensors: Trifluoroacetophenone derivatives were synthesized with a hexasubstituted benzene ring as a preorganized spacer (see scheme) and their characteristics as ionophores were examined for use in ion-selective electrodes. The electrode membranes based on these neutral carriers combined with a cationic additive showed a monoanionic Nernstian response to underivatized phenylalanine, with excellent selectivity towards other essential amino acids and inorganic anions.

Original language	English
Pages (from-to)	3005-3007
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	41
Issue number	16
DOIs	https://doi.org/10.1002/1521-3773(20020816)41:16<3005::AID-ANIE3005>3.0.CO;2-F
Publication status	Published - 2002 Aug 16
Externally published	Yes

Keywords

Amino acids
Ionophores
Molecular recognition
Sensors

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/1521-3773(20020816)41:16<3005::AID-ANIE3005>3.0.CO;2-F

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abstract = "Selective sensors: Trifluoroacetophenone derivatives were synthesized with a hexasubstituted benzene ring as a preorganized spacer (see scheme) and their characteristics as ionophores were examined for use in ion-selective electrodes. The electrode membranes based on these neutral carriers combined with a cationic additive showed a monoanionic Nernstian response to underivatized phenylalanine, with excellent selectivity towards other essential amino acids and inorganic anions.",

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T1 - Trifluoroacetophenone derivatives as amino acid selective ionophores for the potentiometric determination of phenylalanine

AU - Sasaki, Shin Ichi

AU - Hashizume, Akio

AU - Citterio, Daniel

AU - Fujii, Eiji

AU - Suzuki, Koji

PY - 2002/8/16

Y1 - 2002/8/16

N2 - Selective sensors: Trifluoroacetophenone derivatives were synthesized with a hexasubstituted benzene ring as a preorganized spacer (see scheme) and their characteristics as ionophores were examined for use in ion-selective electrodes. The electrode membranes based on these neutral carriers combined with a cationic additive showed a monoanionic Nernstian response to underivatized phenylalanine, with excellent selectivity towards other essential amino acids and inorganic anions.

AB - Selective sensors: Trifluoroacetophenone derivatives were synthesized with a hexasubstituted benzene ring as a preorganized spacer (see scheme) and their characteristics as ionophores were examined for use in ion-selective electrodes. The electrode membranes based on these neutral carriers combined with a cationic additive showed a monoanionic Nernstian response to underivatized phenylalanine, with excellent selectivity towards other essential amino acids and inorganic anions.

KW - Amino acids

KW - Ionophores

KW - Molecular recognition

KW - Sensors

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Trifluoroacetophenone derivatives as amino acid selective ionophores for the potentiometric determination of phenylalanine

Abstract

Keywords

ASJC Scopus subject areas

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