Trifluoroacetophenone derivatives as amino acid selective ionophores for the potentiometric determination of phenylalanine

Shin Ichi Sasaki, Akio Hashizume, Daniel Citterio, Eiji Fujii, Koji Suzuki

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Selective sensors: Trifluoroacetophenone derivatives were synthesized with a hexasubstituted benzene ring as a preorganized spacer (see scheme) and their characteristics as ionophores were examined for use in ion-selective electrodes. The electrode membranes based on these neutral carriers combined with a cationic additive showed a monoanionic Nernstian response to underivatized phenylalanine, with excellent selectivity towards other essential amino acids and inorganic anions.

Original languageEnglish
Pages (from-to)3005-3007
Number of pages3
JournalAngewandte Chemie - International Edition
Volume41
Issue number16
DOIs
Publication statusPublished - 2002 Aug 16

Keywords

  • Amino acids
  • Ionophores
  • Molecular recognition
  • Sensors

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Fingerprint Dive into the research topics of 'Trifluoroacetophenone derivatives as amino acid selective ionophores for the potentiometric determination of phenylalanine'. Together they form a unique fingerprint.

  • Cite this