Trifluoroacetophenone derivatives as amino acid selective ionophores for the potentiometric determination of phenylalanine

Shin Ichi Sasaki, Akio Hashizume, Daniel Citterio, Eiji Fujii, Koji Suzuki

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Selective sensors: Trifluoroacetophenone derivatives were synthesized with a hexasubstituted benzene ring as a preorganized spacer (see scheme) and their characteristics as ionophores were examined for use in ion-selective electrodes. The electrode membranes based on these neutral carriers combined with a cationic additive showed a monoanionic Nernstian response to underivatized phenylalanine, with excellent selectivity towards other essential amino acids and inorganic anions.

Original languageEnglish
Pages (from-to)3005-3007
Number of pages3
JournalAngewandte Chemie - International Edition
Volume41
Issue number16
DOIs
Publication statusPublished - 2002 Aug 16
Externally publishedYes

Fingerprint

Ionophores
Essential Amino Acids
Benzene
Phenylalanine
Anions
Amino acids
Negative ions
Derivatives
Membranes
Amino Acids
Electrodes
Sensors
Ion-Selective Electrodes

Keywords

  • Amino acids
  • Ionophores
  • Molecular recognition
  • Sensors

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Trifluoroacetophenone derivatives as amino acid selective ionophores for the potentiometric determination of phenylalanine. / Sasaki, Shin Ichi; Hashizume, Akio; Citterio, Daniel; Fujii, Eiji; Suzuki, Koji.

In: Angewandte Chemie - International Edition, Vol. 41, No. 16, 16.08.2002, p. 3005-3007.

Research output: Contribution to journalArticle

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