Two different isoforms of desmocollin are recognized by autoantibodies in various types of pemphigus

T. Hashimoto, T. Ebihara, T. Nishikawa

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We have previously reported that, in addition to well-known pemphigus antigens (desmoglein and pemphigus vulgaris antigen), desmocollin (Dsc), another desmosomal cadherin, is recognized by certain pemphigus sera. Furthermore, we noticed that two Dsc species with a slightly different relative molecular weight were recognized by various pemphigus sera. This difference may contribute to the different clinicopathological features between the subcorneal pustular dermatosis type and the intraepidermal neutrophilic IgA dermatosis type of intercellular IgA vesiculopustular dermatosis.

Original languageEnglish
Pages (from-to)124-125
Number of pages2
JournalDermatology
Volume189
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 1994 Jan 1

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Keywords

  • Cadherin
  • Desmocollin
  • Desmosome
  • Intercellular IgA vesiculopustular dermatosis
  • Pemphigus

ASJC Scopus subject areas

  • Dermatology

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