Two new diterpenoids from Plectranthus nummularius BRIQ

Y. Narukawa; N. Shimizu; K. Shimotohno; T. Takeda

doi:10.1248/cpb.49.1182

Two new diterpenoids from Plectranthus nummularius BRIQ

Y. Narukawa, N. Shimizu, K. Shimotohno, T. Takeda

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Two new antioxidative diterpenoids, plectranthol A (3)[19-O-(3,4-dihydroxybenzoyl)-11,12-dihydroxy-20(10→5)-abeo-abieta- 1(10),6,8,11,13-tetraene] and plectranthol B (4)[12-O-(3-methyl-2-butenoyl)-19-O-(3, 4-di-hydroxybenzoyl)-11-hydroxyabieta- 8,11,13-triene] along with two known diterpenoids, parvifloron E (1) and F (2) were isolated from the leaves of Plectranthus nummularius BRIQ. Antioxidative activities of the compounds were measured by the α,α-diphenyl-β-picrylhydrazyl (DPPH) method.

Original language	English
Pages (from-to)	1182-1184
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	49
Issue number	9
DOIs	https://doi.org/10.1248/cpb.49.1182
Publication status	Published - 2001

Keywords

Abietane type diterpenoid
Antioxidative activity
Labiatae
Plectranthus nummularius

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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10.1248/cpb.49.1182

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title = "Two new diterpenoids from Plectranthus nummularius BRIQ",

abstract = "Two new antioxidative diterpenoids, plectranthol A (3)[19-O-(3,4-dihydroxybenzoyl)-11,12-dihydroxy-20(10→5)-abeo-abieta- 1(10),6,8,11,13-tetraene] and plectranthol B (4)[12-O-(3-methyl-2-butenoyl)-19-O-(3, 4-di-hydroxybenzoyl)-11-hydroxyabieta- 8,11,13-triene] along with two known diterpenoids, parvifloron E (1) and F (2) were isolated from the leaves of Plectranthus nummularius BRIQ. Antioxidative activities of the compounds were measured by the α,α-diphenyl-β-picrylhydrazyl (DPPH) method.",

keywords = "Abietane type diterpenoid, Antioxidative activity, Labiatae, Plectranthus nummularius",

author = "Y. Narukawa and N. Shimizu and K. Shimotohno and T. Takeda",

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doi = "10.1248/cpb.49.1182",

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AU - Narukawa, Y.

AU - Shimizu, N.

AU - Shimotohno, K.

AU - Takeda, T.

PY - 2001

Y1 - 2001

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KW - Abietane type diterpenoid

KW - Antioxidative activity

KW - Labiatae

KW - Plectranthus nummularius

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Two new diterpenoids from Plectranthus nummularius BRIQ

Abstract

Keywords

ASJC Scopus subject areas

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