Ultrafast 1D MR thermometry using phase or frequency mapping

Chang Sheng Mei, Robert V. Mulkern, Koichi Oshio, Nan Kuei Chen, Bruno Madore, Lawrence P. Panych, Kullervo Hynynen, Nathan J. McDannold

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Object To develop an ultrafastMRI-based temperaturemonitoring method for application during rapid ultrasound exposures in moving organs. Materials and methods A slice selective 90? ? 180? pair of RF pulses was used to solicit an echo from a column, which was then sampled with a train of gradient echoes. In a gel phantom, phase changes of each echo were compared to standard gradient-echo thermometry, and temperature monitoring was tested during focused ultrasound sonications. Signal-to-noise ratio (SNR) performance was evaluated in vivo in a rabbit brain, and feasibility was tested in a human heart. Results The correlation between each echo in the acquisition and MRI-based temperature measurements was good (R = 0.98 ± 0.03). A temperature sampling rate of 19Hzwas achieved at 3T in the gel phantom. It was possible to acquire the water frequency in the beating heart muscle with 5-Hz sampling rate during a breath hold. Conclusion Ultrafast thermometry via phase or frequency monitoring along single columns was demonstrated. With a temporal resolution around 50 ms, it may be possible to monitor focal heating produced by short ultrasound pulses.

Original languageEnglish
Pages (from-to)5-14
Number of pages10
JournalMagnetic Resonance Materials in Physics, Biology and Medicine
Volume25
Issue number1
DOIs
Publication statusPublished - 2012 Feb
Externally publishedYes

Fingerprint

Thermometry
Temperature
Gels
Sonication
Signal-To-Noise Ratio
Heating
Myocardium
Rabbits
Water
Brain

Keywords

  • Echo-planar magnetic resonance imaging
  • MR spectroscopy
  • Proton resonance frequency shift
  • Thermometry

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Ultrafast 1D MR thermometry using phase or frequency mapping. / Mei, Chang Sheng; Mulkern, Robert V.; Oshio, Koichi; Chen, Nan Kuei; Madore, Bruno; Panych, Lawrence P.; Hynynen, Kullervo; McDannold, Nathan J.

In: Magnetic Resonance Materials in Physics, Biology and Medicine, Vol. 25, No. 1, 02.2012, p. 5-14.

Research output: Contribution to journalArticle

Mei, CS, Mulkern, RV, Oshio, K, Chen, NK, Madore, B, Panych, LP, Hynynen, K & McDannold, NJ 2012, 'Ultrafast 1D MR thermometry using phase or frequency mapping', Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 25, no. 1, pp. 5-14. https://doi.org/10.1007/s10334-011-0272-9
Mei, Chang Sheng ; Mulkern, Robert V. ; Oshio, Koichi ; Chen, Nan Kuei ; Madore, Bruno ; Panych, Lawrence P. ; Hynynen, Kullervo ; McDannold, Nathan J. / Ultrafast 1D MR thermometry using phase or frequency mapping. In: Magnetic Resonance Materials in Physics, Biology and Medicine. 2012 ; Vol. 25, No. 1. pp. 5-14.
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