Ultrastructure of Merkel-like cells labeled with carbocyanine dye in the non-taste lingual epithelium of the axolotl

Takatoshi Nagai, Hiromichi Koyama

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Fluorescent carbocyanine dye (diI), applied to the glossopharyngeal (IX) nerve of the axolotl, transneuronally labeled solitary cells in the non-taste lingual epithelium. With diaminobenzidine (DAB), the diI was photoconverted to a dark, electron-dense product. The labeled cell had a large nucleus with invaginations, dense-cored vesicles in the cytoplasm, and finger-like processes. These are reminiscent of morphological features of cutaneous Merkel cells, suggesting that solitary cells innervated by the IX nerve are associated with mechanosensory function of the IX nerve system.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalNeuroscience Letters
Issue number1
Publication statusPublished - 1994 Aug 29



  • Fluorescent dyes
  • Lingual epithelium
  • Mechanotransduction
  • Merkel cell
  • Photoconversion
  • Salamander
  • Transmission electron microscopy

ASJC Scopus subject areas

  • Neuroscience(all)

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