Umbilical cord length in urinary tract abnormalities associated with oligohydramnios: Evidence regarding developmental pathogenesis

Kosuke Izumi, Kenneth Lyons Jones, Kenjiro Kosaki, Kurt Benirschke

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We performed a retrospective review of the length of the umbilical cords of stillborn fetuses with renal agenesis, cystic kidneys, and bladder outlet obstruction and compared the cord length with normative data. Among the 41 cases, 31 had umbilical cord lengths that were shorter than average. However, the remaining 10 cases had an average to increased cord length. Urinary output in those cases might have been sufficient in early pregnancy to allow adequate fetal activity and sufficient umbilical cord lengthening. We suggest that the length of the umbilical cord can have implications relative to the developmental pathogenesis of some congenital urinary tract abnormalities.

Original languageEnglish
Pages (from-to)233-240
Number of pages8
JournalFetal and Pediatric Pathology
Volume25
Issue number5
DOIs
Publication statusPublished - 2006 Sep

Fingerprint

Oligohydramnios
Umbilical Cord
Urinary Tract
Cystic Kidney Diseases
Urinary Bladder Neck Obstruction
Fetal Movement
Fetus
Pregnancy

Keywords

  • Abnormalities
  • Developmental defect
  • Oligohydramnios
  • Pathogenesis
  • Umbilical
  • Urinary

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Pediatrics, Perinatology, and Child Health

Cite this

Umbilical cord length in urinary tract abnormalities associated with oligohydramnios : Evidence regarding developmental pathogenesis. / Izumi, Kosuke; Jones, Kenneth Lyons; Kosaki, Kenjiro; Benirschke, Kurt.

In: Fetal and Pediatric Pathology, Vol. 25, No. 5, 09.2006, p. 233-240.

Research output: Contribution to journalArticle

@article{b09722beec1d4e389301587d096736c6,
title = "Umbilical cord length in urinary tract abnormalities associated with oligohydramnios: Evidence regarding developmental pathogenesis",
abstract = "We performed a retrospective review of the length of the umbilical cords of stillborn fetuses with renal agenesis, cystic kidneys, and bladder outlet obstruction and compared the cord length with normative data. Among the 41 cases, 31 had umbilical cord lengths that were shorter than average. However, the remaining 10 cases had an average to increased cord length. Urinary output in those cases might have been sufficient in early pregnancy to allow adequate fetal activity and sufficient umbilical cord lengthening. We suggest that the length of the umbilical cord can have implications relative to the developmental pathogenesis of some congenital urinary tract abnormalities.",
keywords = "Abnormalities, Developmental defect, Oligohydramnios, Pathogenesis, Umbilical, Urinary",
author = "Kosuke Izumi and Jones, {Kenneth Lyons} and Kenjiro Kosaki and Kurt Benirschke",
year = "2006",
month = "9",
doi = "10.1080/15513810601123326",
language = "English",
volume = "25",
pages = "233--240",
journal = "Fetal and Pediatric Pathology",
issn = "1551-3815",
publisher = "Informa Healthcare",
number = "5",

}

TY - JOUR

T1 - Umbilical cord length in urinary tract abnormalities associated with oligohydramnios

T2 - Evidence regarding developmental pathogenesis

AU - Izumi, Kosuke

AU - Jones, Kenneth Lyons

AU - Kosaki, Kenjiro

AU - Benirschke, Kurt

PY - 2006/9

Y1 - 2006/9

N2 - We performed a retrospective review of the length of the umbilical cords of stillborn fetuses with renal agenesis, cystic kidneys, and bladder outlet obstruction and compared the cord length with normative data. Among the 41 cases, 31 had umbilical cord lengths that were shorter than average. However, the remaining 10 cases had an average to increased cord length. Urinary output in those cases might have been sufficient in early pregnancy to allow adequate fetal activity and sufficient umbilical cord lengthening. We suggest that the length of the umbilical cord can have implications relative to the developmental pathogenesis of some congenital urinary tract abnormalities.

AB - We performed a retrospective review of the length of the umbilical cords of stillborn fetuses with renal agenesis, cystic kidneys, and bladder outlet obstruction and compared the cord length with normative data. Among the 41 cases, 31 had umbilical cord lengths that were shorter than average. However, the remaining 10 cases had an average to increased cord length. Urinary output in those cases might have been sufficient in early pregnancy to allow adequate fetal activity and sufficient umbilical cord lengthening. We suggest that the length of the umbilical cord can have implications relative to the developmental pathogenesis of some congenital urinary tract abnormalities.

KW - Abnormalities

KW - Developmental defect

KW - Oligohydramnios

KW - Pathogenesis

KW - Umbilical

KW - Urinary

UR - http://www.scopus.com/inward/record.url?scp=34248573756&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34248573756&partnerID=8YFLogxK

U2 - 10.1080/15513810601123326

DO - 10.1080/15513810601123326

M3 - Article

C2 - 17438663

AN - SCOPUS:34248573756

VL - 25

SP - 233

EP - 240

JO - Fetal and Pediatric Pathology

JF - Fetal and Pediatric Pathology

SN - 1551-3815

IS - 5

ER -