Abstract
Hippocampal sharp waves (SWs)/ripples represent the reactivation of neurons involved in recently acquired memory and are crucial for memory consolidation. By labeling active cells with fluorescent protein under the control of an immediate-early gene promoter, we found that neurons that had been activated while mice explored a novel environment were preferentially reactivated during spontaneous SWs in hippocampal slices in vitro. During SWs, the reactivated neurons received strong excitatory synaptic inputs as opposed to a globally tuned network balance between excitation and inhibition.
Original language | English |
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Pages (from-to) | 503-505 |
Number of pages | 3 |
Journal | Nature Neuroscience |
Volume | 17 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2014 Apr |
Externally published | Yes |
ASJC Scopus subject areas
- Neuroscience(all)