Abstract
Ruthenium-catalyzed alkenylation of 2'-alkoxyacetophenones with alkenylboronates provides ortho C-H alkenylation products without sacrificing an ether functional group at the other ortho position. Both excellent chemoselectivity and high product yields are achieved with an aryloxo ruthenium complex. The effective suppression of the C-O bond cleavage was attained by coordination of the alkenyl moiety in the C-H alkenylation product to the ruthenium center.
| Original language | English |
|---|---|
| Pages (from-to) | 855-858 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 11 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2009 Feb 19 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Ueno, S., Kochi, T., Chatani, N., & Kakiuchi, F. (2009). Unique effect of coordination of an alkene moiety in products on Ruthenium-catalyzed chemoselective C-H alkenylation. Organic Letters, 11(4), 855-858. https://doi.org/10.1021/ol802819b