Unusual left ventricular dilatation without functional or biochemical impairment in normotensive extremely overweight Japanese professional sumo wrestlers

Norimitsu Kinoshita, Shohei Onishi, Satoshi Yamamoto, Kimio Yamada, Yuko Oguma, Fuminori Katsukawa, Hajime Yamazaki

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

To explore the physiologic limit of left ventricular (LV) enlargement, we performed echocardiography and air displacement plethysmography to respectively assess LV dimension and function and the body composition of Japanese professional sumo wrestlers. After excluding subjects with cardiovascular disease, hypertension, plasma brain natriuretic peptide (BNP) ≥17.9 pg/ml, diabetes mellitus, or asthma, 331 subjects (mean ± SD age, 21.6 ± 3.7 years; height 179.2 ± 5.3 cm; weight 1,17.9 ± 21.5 kg; percent fat, 29.6 ± 6.6%) were analyzed. LV end-diastolic dimension averaged 58.4 ± 3.7 mm and was within the generally regarded normal limit (≤54 mm) in 14.5% of subjects, but was ≥60 mm in 41.1% of subjects. LV septal and posterior wall thicknesses were 10.3 ± 0.9 and 10.2 ± 0.9 mm, respectively. Peak E- and A-wave velocities, E/A ratio, LV fractional shortening, and BNP were 96 ± 16 and 51 ± 13 cm/s, 2.0 ± 0.7, 33.5 ± 4.5%, and 3.1 ± 3.7 pg/ml, respectively. LV end-diastolic dimension was not correlated with these indexes of LV function or with plasma BNP levels, but was significantly correlated with height, weight, body surface area, fat-free mass, and fat mass. These results show that among very large, highly trained, professional athletes, LV end-diastolic dimension frequently exceeds the traditionally accepted upper limit of normal for the general population. This increase in LV end-diastolic dimension may thus represent an extreme example of the physiologic adaptation of the athlete's heart.

Original languageEnglish
Pages (from-to)699-703
Number of pages5
JournalAmerican Journal of Cardiology
Volume91
Issue number6
DOIs
Publication statusPublished - 2003 Mar 15
Externally publishedYes

Fingerprint

Brain Natriuretic Peptide
Dilatation
Fats
Left Ventricular Function
Athletes
Physiological Adaptation
Weights and Measures
Plethysmography
Body Surface Area
Body Composition
Echocardiography
Diabetes Mellitus
Cardiovascular Diseases
Asthma
Air
Hypertension
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Unusual left ventricular dilatation without functional or biochemical impairment in normotensive extremely overweight Japanese professional sumo wrestlers. / Kinoshita, Norimitsu; Onishi, Shohei; Yamamoto, Satoshi; Yamada, Kimio; Oguma, Yuko; Katsukawa, Fuminori; Yamazaki, Hajime.

In: American Journal of Cardiology, Vol. 91, No. 6, 15.03.2003, p. 699-703.

Research output: Contribution to journalArticle

@article{f8d7f9626de84f108154102d88617362,
title = "Unusual left ventricular dilatation without functional or biochemical impairment in normotensive extremely overweight Japanese professional sumo wrestlers",
abstract = "To explore the physiologic limit of left ventricular (LV) enlargement, we performed echocardiography and air displacement plethysmography to respectively assess LV dimension and function and the body composition of Japanese professional sumo wrestlers. After excluding subjects with cardiovascular disease, hypertension, plasma brain natriuretic peptide (BNP) ≥17.9 pg/ml, diabetes mellitus, or asthma, 331 subjects (mean ± SD age, 21.6 ± 3.7 years; height 179.2 ± 5.3 cm; weight 1,17.9 ± 21.5 kg; percent fat, 29.6 ± 6.6{\%}) were analyzed. LV end-diastolic dimension averaged 58.4 ± 3.7 mm and was within the generally regarded normal limit (≤54 mm) in 14.5{\%} of subjects, but was ≥60 mm in 41.1{\%} of subjects. LV septal and posterior wall thicknesses were 10.3 ± 0.9 and 10.2 ± 0.9 mm, respectively. Peak E- and A-wave velocities, E/A ratio, LV fractional shortening, and BNP were 96 ± 16 and 51 ± 13 cm/s, 2.0 ± 0.7, 33.5 ± 4.5{\%}, and 3.1 ± 3.7 pg/ml, respectively. LV end-diastolic dimension was not correlated with these indexes of LV function or with plasma BNP levels, but was significantly correlated with height, weight, body surface area, fat-free mass, and fat mass. These results show that among very large, highly trained, professional athletes, LV end-diastolic dimension frequently exceeds the traditionally accepted upper limit of normal for the general population. This increase in LV end-diastolic dimension may thus represent an extreme example of the physiologic adaptation of the athlete's heart.",
author = "Norimitsu Kinoshita and Shohei Onishi and Satoshi Yamamoto and Kimio Yamada and Yuko Oguma and Fuminori Katsukawa and Hajime Yamazaki",
year = "2003",
month = "3",
day = "15",
doi = "10.1016/S0002-9149(02)03407-0",
language = "English",
volume = "91",
pages = "699--703",
journal = "American Journal of Cardiology",
issn = "0002-9149",
publisher = "Elsevier Inc.",
number = "6",

}

TY - JOUR

T1 - Unusual left ventricular dilatation without functional or biochemical impairment in normotensive extremely overweight Japanese professional sumo wrestlers

AU - Kinoshita, Norimitsu

AU - Onishi, Shohei

AU - Yamamoto, Satoshi

AU - Yamada, Kimio

AU - Oguma, Yuko

AU - Katsukawa, Fuminori

AU - Yamazaki, Hajime

PY - 2003/3/15

Y1 - 2003/3/15

N2 - To explore the physiologic limit of left ventricular (LV) enlargement, we performed echocardiography and air displacement plethysmography to respectively assess LV dimension and function and the body composition of Japanese professional sumo wrestlers. After excluding subjects with cardiovascular disease, hypertension, plasma brain natriuretic peptide (BNP) ≥17.9 pg/ml, diabetes mellitus, or asthma, 331 subjects (mean ± SD age, 21.6 ± 3.7 years; height 179.2 ± 5.3 cm; weight 1,17.9 ± 21.5 kg; percent fat, 29.6 ± 6.6%) were analyzed. LV end-diastolic dimension averaged 58.4 ± 3.7 mm and was within the generally regarded normal limit (≤54 mm) in 14.5% of subjects, but was ≥60 mm in 41.1% of subjects. LV septal and posterior wall thicknesses were 10.3 ± 0.9 and 10.2 ± 0.9 mm, respectively. Peak E- and A-wave velocities, E/A ratio, LV fractional shortening, and BNP were 96 ± 16 and 51 ± 13 cm/s, 2.0 ± 0.7, 33.5 ± 4.5%, and 3.1 ± 3.7 pg/ml, respectively. LV end-diastolic dimension was not correlated with these indexes of LV function or with plasma BNP levels, but was significantly correlated with height, weight, body surface area, fat-free mass, and fat mass. These results show that among very large, highly trained, professional athletes, LV end-diastolic dimension frequently exceeds the traditionally accepted upper limit of normal for the general population. This increase in LV end-diastolic dimension may thus represent an extreme example of the physiologic adaptation of the athlete's heart.

AB - To explore the physiologic limit of left ventricular (LV) enlargement, we performed echocardiography and air displacement plethysmography to respectively assess LV dimension and function and the body composition of Japanese professional sumo wrestlers. After excluding subjects with cardiovascular disease, hypertension, plasma brain natriuretic peptide (BNP) ≥17.9 pg/ml, diabetes mellitus, or asthma, 331 subjects (mean ± SD age, 21.6 ± 3.7 years; height 179.2 ± 5.3 cm; weight 1,17.9 ± 21.5 kg; percent fat, 29.6 ± 6.6%) were analyzed. LV end-diastolic dimension averaged 58.4 ± 3.7 mm and was within the generally regarded normal limit (≤54 mm) in 14.5% of subjects, but was ≥60 mm in 41.1% of subjects. LV septal and posterior wall thicknesses were 10.3 ± 0.9 and 10.2 ± 0.9 mm, respectively. Peak E- and A-wave velocities, E/A ratio, LV fractional shortening, and BNP were 96 ± 16 and 51 ± 13 cm/s, 2.0 ± 0.7, 33.5 ± 4.5%, and 3.1 ± 3.7 pg/ml, respectively. LV end-diastolic dimension was not correlated with these indexes of LV function or with plasma BNP levels, but was significantly correlated with height, weight, body surface area, fat-free mass, and fat mass. These results show that among very large, highly trained, professional athletes, LV end-diastolic dimension frequently exceeds the traditionally accepted upper limit of normal for the general population. This increase in LV end-diastolic dimension may thus represent an extreme example of the physiologic adaptation of the athlete's heart.

UR - http://www.scopus.com/inward/record.url?scp=0037443680&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037443680&partnerID=8YFLogxK

U2 - 10.1016/S0002-9149(02)03407-0

DO - 10.1016/S0002-9149(02)03407-0

M3 - Article

C2 - 12633801

AN - SCOPUS:0037443680

VL - 91

SP - 699

EP - 703

JO - American Journal of Cardiology

JF - American Journal of Cardiology

SN - 0002-9149

IS - 6

ER -