@article{f4769733699f485aa4e8a94d95506b39,
title = "Up-regulated expression of murine Mcl1/EAT, a Bcl-2 related gene, in the early stage of differentiation of murine embryonal carcinoma cells and embryonic stem cells",
abstract = "We have cloned a murine homologue of the human Mcl1/EAT gene, a Bcl-2 related gene. Sequence analysis revealed that murine Mcl1/EAT (mMcl1/EAT) has three Bcl-2 homology domains, two PEST sequences, and immediate response boxes (IRB). The presence of IRB indicates that mMcl1/EAT is an immediate- early gene. mMcl1/EAT increases dramatically with exposure to retinoic acid in murine embryonal carcinoma cell lines (F9 and PCC3) as well as embryonic stem cells, both of which are models of early embryogenesis.",
keywords = "(Mouse), Bcl-2, Embryonal carcinoma, Embryonic stem cell, Mcll/EAT, cDNA",
author = "Hajime Okita and Akihiro Umezawa and Atsushi Suzuki and Hata, {Jun Ichi}",
note = "Funding Information: The authors are grateful to H. Ikeshima-Kataoka for the gift of the cDNA library. The authors also thank J. Ozawa, K. Otsuki, S. Kusakari, H. Abe and M. Takahashi for their technical assistance, Mr. K. Takeichi for photographic assistance, and Drs. T. Yamada, H. Kikuchi, T. Ando, F. Urano, A. Hashiguchi, M. Sano and T. Atsumi for discussion. This work was supported in part by a grant from the Ministry of Education, Science and Culture to J.H. and A.U., by Keio University Special Grant-in-Aid for Innovative Collaborative Research Project to J.H. and A.U., by a grant from the Keio Medical Association to H.O., and by a National Grant-in-Aid for the Establishment of a High-Tech Research Center at Private Universities.",
year = "1998",
month = jul,
day = "9",
doi = "10.1016/S0167-4781(98)00059-1",
language = "English",
volume = "1398",
pages = "335--341",
journal = "Biochimica et Biophysica Acta - Gene Structure and Expression",
issn = "0167-4781",
publisher = "Elsevier BV",
number = "3",
}