Use of adult marrow mesenchymal stem cells for regeneration of cardiomyocytes

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Abstract

Bone marrow cells have been suggested to have multilineage plasticity including formation of cardiac tissue. We have established a cardiomyogenic (CMG) cell line from mouse bone marrow stromal cells that can be induced to differentiate into cardiomyocytes in vitro by 5-azacytidine treatment. A number of lines of evidence confirm the cardiomyocyte characteristics of CMG cells.

Original languageEnglish
Pages (from-to)S25-S27
JournalBone Marrow Transplantation
Volume32
DOIs
Publication statusPublished - 2003 Aug

Keywords

  • Bone marrow
  • Cardiomyocytes
  • Mesenchymal stem cell
  • Regenerative medicine

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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