Abstract
The stereoselective conversion of the naturally occurring optically active cyclitol, L-quebrachitol 2, into antifungal β-methoxyacrylate, oudemansin X 1 is described. This first total synthesis of 1 fully confirmed the proposed absolute configuration of the antibiotic and showed the importance of 2 as a versatile chiral starting material in natural product syntheses.
| Original language | English |
|---|---|
| Pages (from-to) | 1957-1962 |
| Number of pages | 6 |
| Journal | Journal of the Chemical Society, Perkin Transactions 1 |
| Issue number | 17 |
| Publication status | Published - 1993 Dec 1 |
ASJC Scopus subject areas
- Chemistry(all)