Vaccines for hypertension and atherosclerosis

Hiroyuki Sasamura, Tatsuhiko Azegami, Hiroshi Itoh

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Both hypertension and atherosclerosis are chronic medical conditions which require continuous therapy. Recent basic and clinical studies have shown that vaccination against the renin-angiotensin system is effective in reducting blood pressure. In the case of atherosclerosis, vaccines targeting endothelial, macrophage, immune system, and lipid metabolism targets have been shown to reduce atherosclerosis in animal models. The development of vaccines for hypertension and atherosclerosis may be an important strategy for the prevention and treatment of these diseases.

Original languageEnglish
Title of host publicationMolecular Vaccines: From Prophylaxis to Therapy - Volume 2
PublisherSpringer International Publishing
Pages451-461
Number of pages11
ISBN (Print)9783319009780, 9783319009773
DOIs
Publication statusPublished - 2014 Jan 1

Fingerprint

Atherosclerosis
Vaccines
Hypertension
Renin-Angiotensin System
Lipid Metabolism
Immune System
Vaccination
Animal Models
Macrophages
Blood Pressure
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

Cite this

Sasamura, H., Azegami, T., & Itoh, H. (2014). Vaccines for hypertension and atherosclerosis. In Molecular Vaccines: From Prophylaxis to Therapy - Volume 2 (pp. 451-461). Springer International Publishing. https://doi.org/10.1007/978-3-319-00978-0_1

Vaccines for hypertension and atherosclerosis. / Sasamura, Hiroyuki; Azegami, Tatsuhiko; Itoh, Hiroshi.

Molecular Vaccines: From Prophylaxis to Therapy - Volume 2. Springer International Publishing, 2014. p. 451-461.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sasamura, H, Azegami, T & Itoh, H 2014, Vaccines for hypertension and atherosclerosis. in Molecular Vaccines: From Prophylaxis to Therapy - Volume 2. Springer International Publishing, pp. 451-461. https://doi.org/10.1007/978-3-319-00978-0_1
Sasamura H, Azegami T, Itoh H. Vaccines for hypertension and atherosclerosis. In Molecular Vaccines: From Prophylaxis to Therapy - Volume 2. Springer International Publishing. 2014. p. 451-461 https://doi.org/10.1007/978-3-319-00978-0_1
Sasamura, Hiroyuki ; Azegami, Tatsuhiko ; Itoh, Hiroshi. / Vaccines for hypertension and atherosclerosis. Molecular Vaccines: From Prophylaxis to Therapy - Volume 2. Springer International Publishing, 2014. pp. 451-461
@inbook{084ab6bdc10c4d32a2a92b7ac26b0c78,
title = "Vaccines for hypertension and atherosclerosis",
abstract = "Both hypertension and atherosclerosis are chronic medical conditions which require continuous therapy. Recent basic and clinical studies have shown that vaccination against the renin-angiotensin system is effective in reducting blood pressure. In the case of atherosclerosis, vaccines targeting endothelial, macrophage, immune system, and lipid metabolism targets have been shown to reduce atherosclerosis in animal models. The development of vaccines for hypertension and atherosclerosis may be an important strategy for the prevention and treatment of these diseases.",
author = "Hiroyuki Sasamura and Tatsuhiko Azegami and Hiroshi Itoh",
year = "2014",
month = "1",
day = "1",
doi = "10.1007/978-3-319-00978-0_1",
language = "English",
isbn = "9783319009780",
pages = "451--461",
booktitle = "Molecular Vaccines: From Prophylaxis to Therapy - Volume 2",
publisher = "Springer International Publishing",

}

TY - CHAP

T1 - Vaccines for hypertension and atherosclerosis

AU - Sasamura, Hiroyuki

AU - Azegami, Tatsuhiko

AU - Itoh, Hiroshi

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Both hypertension and atherosclerosis are chronic medical conditions which require continuous therapy. Recent basic and clinical studies have shown that vaccination against the renin-angiotensin system is effective in reducting blood pressure. In the case of atherosclerosis, vaccines targeting endothelial, macrophage, immune system, and lipid metabolism targets have been shown to reduce atherosclerosis in animal models. The development of vaccines for hypertension and atherosclerosis may be an important strategy for the prevention and treatment of these diseases.

AB - Both hypertension and atherosclerosis are chronic medical conditions which require continuous therapy. Recent basic and clinical studies have shown that vaccination against the renin-angiotensin system is effective in reducting blood pressure. In the case of atherosclerosis, vaccines targeting endothelial, macrophage, immune system, and lipid metabolism targets have been shown to reduce atherosclerosis in animal models. The development of vaccines for hypertension and atherosclerosis may be an important strategy for the prevention and treatment of these diseases.

UR - http://www.scopus.com/inward/record.url?scp=84957691538&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84957691538&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-00978-0_1

DO - 10.1007/978-3-319-00978-0_1

M3 - Chapter

AN - SCOPUS:84957691538

SN - 9783319009780

SN - 9783319009773

SP - 451

EP - 461

BT - Molecular Vaccines: From Prophylaxis to Therapy - Volume 2

PB - Springer International Publishing

ER -