Vaccines for hypertension and atherosclerosis

Hiroyuki Sasamura, Tatsuhiko Azegami, Hiroshi Itoh

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Both hypertension and atherosclerosis are chronic medical conditions which require continuous therapy. Recent basic and clinical studies have shown that vaccination against the renin-angiotensin system is effective in reducting blood pressure. In the case of atherosclerosis, vaccines targeting endothelial, macrophage, immune system, and lipid metabolism targets have been shown to reduce atherosclerosis in animal models. The development of vaccines for hypertension and atherosclerosis may be an important strategy for the prevention and treatment of these diseases.

Original languageEnglish
Title of host publicationMolecular Vaccines: From Prophylaxis to Therapy - Volume 2
PublisherSpringer International Publishing
Pages451-461
Number of pages11
ISBN (Print)9783319009780, 9783319009773
DOIs
Publication statusPublished - 2014 Jan 1

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ASJC Scopus subject areas

  • Medicine(all)
  • Immunology and Microbiology(all)

Cite this

Sasamura, H., Azegami, T., & Itoh, H. (2014). Vaccines for hypertension and atherosclerosis. In Molecular Vaccines: From Prophylaxis to Therapy - Volume 2 (pp. 451-461). Springer International Publishing. https://doi.org/10.1007/978-3-319-00978-0_1