Validation of practical diffusion approximation for virtual near infrared spectroscopy using a digital head phantom

Yosuke Oki, Hiroshi Kawaguchi, Eiji Okada

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    3 Citations (Scopus)

    Abstract

    Light propagation in the digital head phantom for virtual near infrared spectroscopy and imaging is calculated by diffusion theory. In theory, diffusion approximation is not valid in a low-scattering cerebrospinal fluid (CSF) layer around the brain. The optical path length and spatial sensitivity profile predicted by the finite element method based upon the diffusion theory are compared with those predicted by the Monte Carlo method to validate a practical implementation of diffusion approximation to light propagation in an adult head. The transport scattering coefficient of the CSF layer is varied from 0.01 to 1.0 mm-1 to evaluate the influence of that layer on the error caused by diffusion approximation. The error is practically ignored and the geometry of the brain surface such as the sulcus structure in the digital head phantom scarcely affects the error when the transport scattering coefficient of the CSF layer is greater than 0.3 mm-1.

    Original languageEnglish
    Pages (from-to)153-159
    Number of pages7
    JournalOptical Review
    Volume16
    Issue number2
    DOIs
    Publication statusPublished - 2009 Mar 1

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    Keywords

    • Diffusion approximation
    • Digital head phantom
    • Finite element method
    • Monte Carlo method
    • Near infrared spectroscopy

    ASJC Scopus subject areas

    • Atomic and Molecular Physics, and Optics

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