Vasculitis associated with septicemia: Case report and review of the literature

Kazuki Kodo, Mariko Hida, S. Omori, T. Mori, Mitsuaki Tokumura, S. Kuramochi, M. Awazu

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We report an unusual case in which infectious endocarditis presented systemic vasculitis and glomerulonephritis as the initial manifestation of the disease. The patient was a 16-year-old girl with congenital cyanotic heart disease who presented with skin purpura, proteinuria, and hematuria. She had hypergammaglobulinemia, cryoglobulinemia, and positive circulating immune complexes. Renal biopsy revealed crescentic glomerulonephritis. Her serum C3 level, which was initially normal, became decreased, and prednisolone and azathioprine were administered with a tentative diagnosis of systemic lupus erythematosus (SLE). Soon after, she developed fever and renal failure. Blood culture grew Streptococcus pyogenes, and the diagnosis of infectious endocarditis was made. Eight cases of systemic vasculitis and glomerulonephritis associated with infectious endocarditis have been described in the literature. Infectious endocarditis should be included in the differential diagnosis of systemic vasculitis and glomerulonephritis.

Original languageEnglish
Pages (from-to)1089-1092
Number of pages4
JournalPediatric Nephrology
Volume16
Issue number12
DOIs
Publication statusPublished - 2001

Fingerprint

Glomerulonephritis
Vasculitis
Endocarditis
Systemic Vasculitis
Sepsis
Hypergammaglobulinemia
Cryoglobulinemia
Purpura
Streptococcus pyogenes
Azathioprine
Hematuria
Prednisolone
Antigen-Antibody Complex
Proteinuria
Systemic Lupus Erythematosus
Renal Insufficiency
Heart Diseases
Differential Diagnosis
Fever
Kidney

Keywords

  • Crescentic glomerulonephritis
  • Infectious endocarditis
  • Purpura
  • Rapidly progressive glomerulonephritis
  • Systemic vasculitis

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Cite this

Vasculitis associated with septicemia : Case report and review of the literature. / Kodo, Kazuki; Hida, Mariko; Omori, S.; Mori, T.; Tokumura, Mitsuaki; Kuramochi, S.; Awazu, M.

In: Pediatric Nephrology, Vol. 16, No. 12, 2001, p. 1089-1092.

Research output: Contribution to journalArticle

Kodo, Kazuki ; Hida, Mariko ; Omori, S. ; Mori, T. ; Tokumura, Mitsuaki ; Kuramochi, S. ; Awazu, M. / Vasculitis associated with septicemia : Case report and review of the literature. In: Pediatric Nephrology. 2001 ; Vol. 16, No. 12. pp. 1089-1092.
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