Abstract
We report an unusual case in which infectious endocarditis presented systemic vasculitis and glomerulonephritis as the initial manifestation of the disease. The patient was a 16-year-old girl with congenital cyanotic heart disease who presented with skin purpura, proteinuria, and hematuria. She had hypergammaglobulinemia, cryoglobulinemia, and positive circulating immune complexes. Renal biopsy revealed crescentic glomerulonephritis. Her serum C3 level, which was initially normal, became decreased, and prednisolone and azathioprine were administered with a tentative diagnosis of systemic lupus erythematosus (SLE). Soon after, she developed fever and renal failure. Blood culture grew Streptococcus pyogenes, and the diagnosis of infectious endocarditis was made. Eight cases of systemic vasculitis and glomerulonephritis associated with infectious endocarditis have been described in the literature. Infectious endocarditis should be included in the differential diagnosis of systemic vasculitis and glomerulonephritis.
| Original language | English |
|---|---|
| Pages (from-to) | 1089-1092 |
| Number of pages | 4 |
| Journal | Pediatric Nephrology |
| Volume | 16 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2001 |
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Keywords
- Crescentic glomerulonephritis
- Infectious endocarditis
- Purpura
- Rapidly progressive glomerulonephritis
- Systemic vasculitis
ASJC Scopus subject areas
- Nephrology
- Pediatrics, Perinatology, and Child Health
Cite this
Vasculitis associated with septicemia : Case report and review of the literature. / Kodo, Kazuki; Hida, Mariko; Omori, S.; Mori, T.; Tokumura, Mitsuaki; Kuramochi, S.; Awazu, M.
In: Pediatric Nephrology, Vol. 16, No. 12, 2001, p. 1089-1092.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Vasculitis associated with septicemia
T2 - Case report and review of the literature
AU - Kodo, Kazuki
AU - Hida, Mariko
AU - Omori, S.
AU - Mori, T.
AU - Tokumura, Mitsuaki
AU - Kuramochi, S.
AU - Awazu, M.
PY - 2001
Y1 - 2001
N2 - We report an unusual case in which infectious endocarditis presented systemic vasculitis and glomerulonephritis as the initial manifestation of the disease. The patient was a 16-year-old girl with congenital cyanotic heart disease who presented with skin purpura, proteinuria, and hematuria. She had hypergammaglobulinemia, cryoglobulinemia, and positive circulating immune complexes. Renal biopsy revealed crescentic glomerulonephritis. Her serum C3 level, which was initially normal, became decreased, and prednisolone and azathioprine were administered with a tentative diagnosis of systemic lupus erythematosus (SLE). Soon after, she developed fever and renal failure. Blood culture grew Streptococcus pyogenes, and the diagnosis of infectious endocarditis was made. Eight cases of systemic vasculitis and glomerulonephritis associated with infectious endocarditis have been described in the literature. Infectious endocarditis should be included in the differential diagnosis of systemic vasculitis and glomerulonephritis.
AB - We report an unusual case in which infectious endocarditis presented systemic vasculitis and glomerulonephritis as the initial manifestation of the disease. The patient was a 16-year-old girl with congenital cyanotic heart disease who presented with skin purpura, proteinuria, and hematuria. She had hypergammaglobulinemia, cryoglobulinemia, and positive circulating immune complexes. Renal biopsy revealed crescentic glomerulonephritis. Her serum C3 level, which was initially normal, became decreased, and prednisolone and azathioprine were administered with a tentative diagnosis of systemic lupus erythematosus (SLE). Soon after, she developed fever and renal failure. Blood culture grew Streptococcus pyogenes, and the diagnosis of infectious endocarditis was made. Eight cases of systemic vasculitis and glomerulonephritis associated with infectious endocarditis have been described in the literature. Infectious endocarditis should be included in the differential diagnosis of systemic vasculitis and glomerulonephritis.
KW - Crescentic glomerulonephritis
KW - Infectious endocarditis
KW - Purpura
KW - Rapidly progressive glomerulonephritis
KW - Systemic vasculitis
UR - http://www.scopus.com/inward/record.url?scp=0035664871&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035664871&partnerID=8YFLogxK
U2 - 10.1007/s004670100035
DO - 10.1007/s004670100035
M3 - Article
C2 - 11793107
AN - SCOPUS:0035664871
VL - 16
SP - 1089
EP - 1092
JO - Pediatric Nephrology
JF - Pediatric Nephrology
SN - 0931-041X
IS - 12
ER -