Vertical and horizontal confocal imaging of single cells on magnetically handleable microplates

T. Teshima, H. Aonuma, H. Onoe, H. Kanuka, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, we purpose the microfabricated system to manipulate single host cells of parasites toward the analysis of invasion at single cell level. We fabricated the microplates made from Parylene and modified the shape and structure of surface by using lithography techniques. This device is able to not only control the shape and morphology of adhering host cells, but also handle them maintaining their adherent property. The ability to manipulate single adherent host cells reveals the unknown triggered key for parasite invasion. This method can be an attractive platform for the manipulation of host cells, the observation of invading microbes and the analysis of interaction between microbe and host cells.

Original languageEnglish
Title of host publicationIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages145-148
Number of pages4
DOIs
Publication statusPublished - 2013
Externally publishedYes
EventIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China
Duration: 2013 Jan 202013 Jan 24

Publication series

NameProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)1084-6999

Other

OtherIEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
CountryTaiwan, Province of China
CityTaipei
Period13/1/2013/1/24

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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