Voluntary contraction enhances spinal reciprocal inhibition induced by patterned electrical stimulation in patients with stroke

Yoko Takahashi, Toshiyuki Fujiwara, Tomofumi Yamaguchi, Hikaru Matsunaga, Michiyuki Kawakami, Kaoru Honaga, Katsuhiro Mizuno, Meigen Liu

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background: Reciprocal inhibition (RI) may be important for recovering locomotion after stroke. Patterned electrical stimulation (PES) can modulate RI in a manner that could be enhanced by voluntary muscle contraction (VC). Objective: To investigate whether VC enhances the PES-induced spinal RI in patients with stroke. Methods: Twelve patients with chronic stroke underwent three 20 min tasks, each on different days: (1) PES (10 pulses, 100 Hz every 2 s) applied to the common peroneal nerve; (2) VC consisting of isometric contraction of the affected-side tibialis anterior muscle; (3) PES combined with VC (PES + VC). RI from the tibialis anterior to the soleus muscle was assessed before, immediately after, and 10, 20, and 30 min after the task. Results: Compared to the baseline, PES + VC significantly increased the changes in reciprocal inhibition at immediately after and 10 min after the task. PES alone significantly increased this change immediately after the task, while VC alone showed no significant increase. Conclusion: VC enhanced the PES-induced plastic changes in RI in patients with stroke. This effect can potentially increase the success rate of newer neurorehabilitative approaches in achieving functional recovery after stroke.

Original languageEnglish
Pages (from-to)99-105
Number of pages7
JournalRestorative Neurology and Neuroscience
Volume36
Issue number1
DOIs
Publication statusPublished - 2018 Jan 1

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Muscle Contraction
Electric Stimulation
Skeletal Muscle
Stroke
Peroneal Nerve
Isometric Contraction
Locomotion
Muscles

Keywords

  • electrical stimulation
  • H-reflex
  • hemiplegia
  • locomotion
  • spasticity
  • spinal plasticity

ASJC Scopus subject areas

  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

Voluntary contraction enhances spinal reciprocal inhibition induced by patterned electrical stimulation in patients with stroke. / Takahashi, Yoko; Fujiwara, Toshiyuki; Yamaguchi, Tomofumi; Matsunaga, Hikaru; Kawakami, Michiyuki; Honaga, Kaoru; Mizuno, Katsuhiro; Liu, Meigen.

In: Restorative Neurology and Neuroscience, Vol. 36, No. 1, 01.01.2018, p. 99-105.

Research output: Contribution to journalArticle

Takahashi, Yoko ; Fujiwara, Toshiyuki ; Yamaguchi, Tomofumi ; Matsunaga, Hikaru ; Kawakami, Michiyuki ; Honaga, Kaoru ; Mizuno, Katsuhiro ; Liu, Meigen. / Voluntary contraction enhances spinal reciprocal inhibition induced by patterned electrical stimulation in patients with stroke. In: Restorative Neurology and Neuroscience. 2018 ; Vol. 36, No. 1. pp. 99-105.
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