Water permeable nanoporous membrane for implantable hemodialysis device

Naoya To, Ippei Sanada, Hikaru Ito, Shinya Morita, Yoshihiko Nanno, Norihisa Miki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper experimentally characterized water permeable nanoporous membranes for hemodialysis applications both in vitro and in vivo. We developed water-permeable and robust nanoporous membrane from a casting solution of polyether sulfone (PES), polyethylene glycol (PEG), and Dimethylacetamide (DMAc). In vitro tests verified that the membrane had higher water permeability than prior work and did not cause any leakage. Then, a hemodialysis device equipped with the developed membranes were connected to rat artery and vein and its permeability characteristics were evaluated. Aqueous filtrate was successfully collected, whose amount was affected by the blood pressure.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages58-60
Number of pages3
ISBN (Print)9780979806476
Publication statusPublished - 2014
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 2014 Oct 262014 Oct 30

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period14/10/2614/10/30

Keywords

  • Hemodialysis system
  • Membrane
  • Poly-ether-sulfone
  • Water permeability

ASJC Scopus subject areas

  • Control and Systems Engineering

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  • Cite this

    To, N., Sanada, I., Ito, H., Morita, S., Nanno, Y., & Miki, N. (2014). Water permeable nanoporous membrane for implantable hemodialysis device. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 58-60). Chemical and Biological Microsystems Society.