Xanthogranulomatous gastritis of the remnant stomach mimicking a malignant tumor: A case report

Akihiko Okamura, Tsunehiro Takahashi, Yoshiro Saikawa, Jumpei Nakadai, Taiki Ono, Rieko Nakamura, Norihito Wada, Hirofumi Kawakubo, Hiroya Takeuchi, Katsura Emoto, Aya Sasaki, Kaori Kameyama, Yuukou Kitagawa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Xanthogranulomas are known to develop in the gallbladder and kidney. Xanthogranuloma of the stomach is a rare disease, and to the best of our knowledge, only a few cases have been reported to date. The present patient was a 64-year-old man who underwent a wide resection of the stomach following a Billroth-I reconstruction for a gastric ulcer ~40 years prior to the current presentation. Due to tarry stools, a gastrointestinal endoscopy was performed, leading to identification of an ulcerated gastric lesion located at the previous suture line at the lesser curvature of the remnant stomach. This lesion was elevated, appearing to indicate a submucosal tumor. Positron emission tomography revealed uptake of fluorodeoxyglucose radiotracer by the tumor. Although not indicated by the biopsy specimens, a malignant tumor of the remnant stomach was suspected, in the form of a malignant gastrointestinal tumor or remnant gastric cancer. Curative resection of the tumor was successfully performed. Histological examination of the resected specimens revealed xanthogranulomatous inflammation consisting of foamy histiocytes and plasma cells, however, no cancer cells were observed. The tumor was diagnosed as xanthogranulomatous gastritis that mimicked a malignant tumor of the remnant stomach. The present study therefore indicates that inflammatory tumors should be considered in the differential diagnosis of malignant tumors.

Original languageEnglish
Pages (from-to)1453-1456
Number of pages4
JournalOncology Letters
Volume11
Issue number2
DOIs
Publication statusPublished - 2016 Feb 1

Fingerprint

Gastric Stump
Gastritis
Neoplasms
Stomach
Gastroenterostomy
Gastrointestinal Endoscopy
Histiocytes
Stomach Ulcer
Rare Diseases
Plasma Cells
Gallbladder
Positron-Emission Tomography
Sutures
Stomach Neoplasms
Differential Diagnosis

Keywords

  • Inflammatory tumor
  • Remnant stomach
  • Stomach
  • Xanthogranuloma
  • Xanthogranulomatous gastritis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Xanthogranulomatous gastritis of the remnant stomach mimicking a malignant tumor : A case report. / Okamura, Akihiko; Takahashi, Tsunehiro; Saikawa, Yoshiro; Nakadai, Jumpei; Ono, Taiki; Nakamura, Rieko; Wada, Norihito; Kawakubo, Hirofumi; Takeuchi, Hiroya; Emoto, Katsura; Sasaki, Aya; Kameyama, Kaori; Kitagawa, Yuukou.

In: Oncology Letters, Vol. 11, No. 2, 01.02.2016, p. 1453-1456.

Research output: Contribution to journalArticle

Okamura, Akihiko ; Takahashi, Tsunehiro ; Saikawa, Yoshiro ; Nakadai, Jumpei ; Ono, Taiki ; Nakamura, Rieko ; Wada, Norihito ; Kawakubo, Hirofumi ; Takeuchi, Hiroya ; Emoto, Katsura ; Sasaki, Aya ; Kameyama, Kaori ; Kitagawa, Yuukou. / Xanthogranulomatous gastritis of the remnant stomach mimicking a malignant tumor : A case report. In: Oncology Letters. 2016 ; Vol. 11, No. 2. pp. 1453-1456.
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