Abstract
Xanthogranulomas are known to develop in the gallbladder and kidney. Xanthogranuloma of the stomach is a rare disease, and to the best of our knowledge, only a few cases have been reported to date. The present patient was a 64-year-old man who underwent a wide resection of the stomach following a Billroth-I reconstruction for a gastric ulcer ~40 years prior to the current presentation. Due to tarry stools, a gastrointestinal endoscopy was performed, leading to identification of an ulcerated gastric lesion located at the previous suture line at the lesser curvature of the remnant stomach. This lesion was elevated, appearing to indicate a submucosal tumor. Positron emission tomography revealed uptake of fluorodeoxyglucose radiotracer by the tumor. Although not indicated by the biopsy specimens, a malignant tumor of the remnant stomach was suspected, in the form of a malignant gastrointestinal tumor or remnant gastric cancer. Curative resection of the tumor was successfully performed. Histological examination of the resected specimens revealed xanthogranulomatous inflammation consisting of foamy histiocytes and plasma cells, however, no cancer cells were observed. The tumor was diagnosed as xanthogranulomatous gastritis that mimicked a malignant tumor of the remnant stomach. The present study therefore indicates that inflammatory tumors should be considered in the differential diagnosis of malignant tumors.
| Original language | English |
|---|---|
| Pages (from-to) | 1453-1456 |
| Number of pages | 4 |
| Journal | Oncology Letters |
| Volume | 11 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2016 Feb 1 |
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Keywords
- Inflammatory tumor
- Remnant stomach
- Stomach
- Xanthogranuloma
- Xanthogranulomatous gastritis
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Xanthogranulomatous gastritis of the remnant stomach mimicking a malignant tumor : A case report. / Okamura, Akihiko; Takahashi, Tsunehiro; Saikawa, Yoshiro; Nakadai, Jumpei; Ono, Taiki; Nakamura, Rieko; Wada, Norihito; Kawakubo, Hirofumi; Takeuchi, Hiroya; Emoto, Katsura; Sasaki, Aya; Kameyama, Kaori; Kitagawa, Yuukou.
In: Oncology Letters, Vol. 11, No. 2, 01.02.2016, p. 1453-1456.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Xanthogranulomatous gastritis of the remnant stomach mimicking a malignant tumor
T2 - A case report
AU - Okamura, Akihiko
AU - Takahashi, Tsunehiro
AU - Saikawa, Yoshiro
AU - Nakadai, Jumpei
AU - Ono, Taiki
AU - Nakamura, Rieko
AU - Wada, Norihito
AU - Kawakubo, Hirofumi
AU - Takeuchi, Hiroya
AU - Emoto, Katsura
AU - Sasaki, Aya
AU - Kameyama, Kaori
AU - Kitagawa, Yuukou
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Xanthogranulomas are known to develop in the gallbladder and kidney. Xanthogranuloma of the stomach is a rare disease, and to the best of our knowledge, only a few cases have been reported to date. The present patient was a 64-year-old man who underwent a wide resection of the stomach following a Billroth-I reconstruction for a gastric ulcer ~40 years prior to the current presentation. Due to tarry stools, a gastrointestinal endoscopy was performed, leading to identification of an ulcerated gastric lesion located at the previous suture line at the lesser curvature of the remnant stomach. This lesion was elevated, appearing to indicate a submucosal tumor. Positron emission tomography revealed uptake of fluorodeoxyglucose radiotracer by the tumor. Although not indicated by the biopsy specimens, a malignant tumor of the remnant stomach was suspected, in the form of a malignant gastrointestinal tumor or remnant gastric cancer. Curative resection of the tumor was successfully performed. Histological examination of the resected specimens revealed xanthogranulomatous inflammation consisting of foamy histiocytes and plasma cells, however, no cancer cells were observed. The tumor was diagnosed as xanthogranulomatous gastritis that mimicked a malignant tumor of the remnant stomach. The present study therefore indicates that inflammatory tumors should be considered in the differential diagnosis of malignant tumors.
AB - Xanthogranulomas are known to develop in the gallbladder and kidney. Xanthogranuloma of the stomach is a rare disease, and to the best of our knowledge, only a few cases have been reported to date. The present patient was a 64-year-old man who underwent a wide resection of the stomach following a Billroth-I reconstruction for a gastric ulcer ~40 years prior to the current presentation. Due to tarry stools, a gastrointestinal endoscopy was performed, leading to identification of an ulcerated gastric lesion located at the previous suture line at the lesser curvature of the remnant stomach. This lesion was elevated, appearing to indicate a submucosal tumor. Positron emission tomography revealed uptake of fluorodeoxyglucose radiotracer by the tumor. Although not indicated by the biopsy specimens, a malignant tumor of the remnant stomach was suspected, in the form of a malignant gastrointestinal tumor or remnant gastric cancer. Curative resection of the tumor was successfully performed. Histological examination of the resected specimens revealed xanthogranulomatous inflammation consisting of foamy histiocytes and plasma cells, however, no cancer cells were observed. The tumor was diagnosed as xanthogranulomatous gastritis that mimicked a malignant tumor of the remnant stomach. The present study therefore indicates that inflammatory tumors should be considered in the differential diagnosis of malignant tumors.
KW - Inflammatory tumor
KW - Remnant stomach
KW - Stomach
KW - Xanthogranuloma
KW - Xanthogranulomatous gastritis
UR - http://www.scopus.com/inward/record.url?scp=84954322525&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84954322525&partnerID=8YFLogxK
U2 - 10.3892/ol.2015.4054
DO - 10.3892/ol.2015.4054
M3 - Article
AN - SCOPUS:84954322525
VL - 11
SP - 1453
EP - 1456
JO - Oncology Letters
JF - Oncology Letters
SN - 1792-1074
IS - 2
ER -