@article{8ad479a9314b45918e3913745d8fc29e,
title = "Zamamistatin, a significant antibacterial bromotyrosine derivative, from the Okinawan sponge Pseudoceratina purpurea",
abstract = "Zamamistatin was isolated from the Okinawan sponge Pseudoceratina purpurea. It was determined to be a novel bromotyrosine derivative by careful analysis of 2D NMR spectra and comparison of its 1H NMR spectrum with those of structurally related compounds. The absolute stereostructure of zamamistatin was determined by the modified Mosher's method. Zamamistatin exhibited significant antibacterial activity against Rhodospirillum salexigens, which has adhering properties.",
keywords = "Absolute stereochemistry, Antibacterial activity, Antifouling agent, Isolation, Structural determination",
author = "Noboru Takada and Reiko Watanabe and Kiyotake Suenaga and Kaoru Yamada and Katsuhiro Ueda and Masaki Kita and Daisuke Uemura",
note = "Funding Information: This work was supported in part by Grants-in-Aid for Scientific Research (No. 11558079) and Scientific Research on Priority Areas (A) (No. 12045235) from the Ministry of Education, Culture, Sports, Science, and Technology, Japan. The authors are indebted to Wako Pure Chemical Industries Ltd. and Banyu Pharmaceutical Co. Ltd. for their financial support. They like to thank Professor P. R. Bergquist of the University of Auckland for identifying the sponge. They would also like to thank Professors R. Noyori and M. Kitamura (COE, Nagoya University) for allowing them to use the NMR instruments.",
year = "2001",
month = jul,
day = "30",
doi = "10.1016/S0040-4039(01)00993-5",
language = "English",
volume = "42",
pages = "5265--5267",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "31",
}