研究成果 1973 2020

フィルター
Article
2019

Age group differences in association between IADL decline and depressive symptoms in community-dwelling elderly

Kiyoshige, E., Kabayama, M., Gondo, Y., Masui, Y., Inagaki, H., Ogawa, M., Nakagawa, T., Yasumoto, S., Akasaka, H., Sugimoto, K., Ikebe, K., Arai, Y., Ishizaki, T., Rakugi, H. & Kamide, K., 2019 11 13, : : BMC Geriatrics. 19, 1, 309.

研究成果: Article

公開
Independent Living
Activities of Daily Living
Age Groups
Depression
Odds Ratio

Age-Related Conjunctival P2Y2 Receptor Alterations in the Cu, Zn-Superoxide Dismutase-1 (Sod1)-Knockout Dry Eye Model Mice

Dogru, M., Shinzawa, M., Kojima, T., Shimizu, T. & Tsubota, K., 2019 11 1, : : Eye & contact lens. 45, 6, p. 405-409 5 p.

研究成果: Article

Purinergic P2Y2 Receptors
Tears
Staining and Labeling
Fluorescein
Messenger RNA
1 引用 (Scopus)

A high BNP level predicts an improvement in exercise tolerance after a successful catheter ablation of persistent atrial fibrillation

Katsumata, Y., Tamura, Y., Kimura, T., Kosaka, S., Sadahiro, T., Nishiyama, T., Aizawa, Y., Azuma, K., Fukuda, K. & Takatsuki, S., 2019 1 1, (Accepted/In press) : : Journal of Cardiovascular Electrophysiology.

研究成果: Article

Exercise Tolerance
Catheter Ablation
Atrial Fibrillation
Heart Failure
Brain Natriuretic Peptide
6 引用 (Scopus)

A high-throughput neurohistological pipeline for brain-wide mesoscale connectivity mapping of the common marmoset

Lin, M. K., Takahashi, Y. S., Huo, B. X., Hanada, M., Nagashima, J., Hata, J., Tolpygo, A. S., Ram, K., Lee, B. C., Miller, M. I., Rosa, M. G., Sasaki, E., Iriki, A., Okano, H. & Mitra, P., 2019 2 5, : : eLife. 8

研究成果: Article

公開
Callithrix
Brain
Pipelines
Throughput
Atlases
1 引用 (Scopus)

A Human Induced Pluripotent Stem Cell-Derived Tissue Model of a Cerebral Tract Connecting Two Cortical Regions

Kirihara, T., Luo, Z., Chow, S. Y. A., Misawa, R., Kawada, J., Shibata, S., Khoyratee, F., Vollette, C. A., Volz, V., Levi, T., Fujii, T. & Ikeuchi, Y., 2019 4 26, : : iScience. 14, p. 301-311 11 p.

研究成果: Article

公開
Induced Pluripotent Stem Cells
Axons
Neurons
Brain
Stem Cells
6 引用 (Scopus)

A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles

Zhang, J. Z., Termglinchan, V., Shao, N. Y., Itzhaki, I., Liu, C., Ma, N., Tian, L., Wang, V. Y., Chang, A. C. Y., Guo, H., Kitani, T., Wu, H., Lam, C. K., Kodo, K., Sayed, N., Blau, H. M. & Wu, J. C., 2019 5 2, : : Cell stem cell. 24, 5, p. 802-811.e5

研究成果: Article

Pharmaceutical Preparations
In Vitro Techniques
3 引用 (Scopus)

Airway M Cells arise in the lower airway due to RANKL signaling and reside in the bronchiolar epithelium associated with iBALT in murine models of respiratory disease

Kimura, S., Mutoh, M., Hisamoto, M., Saito, H., Takahashi, S., Asakura, T., Ishii, M., Nakamura, Y., Iida, J., Hase, K. & Iwanaga, T., 2019 1 1, : : Frontiers in Immunology. 10, JUN, 1323.

研究成果: Article

公開
Lymphoid Tissue
Bronchi
Epithelium
Respiratory System
Glycoproteins

A Japanese nationwide survey on the cryopreservation of embryos, oocytes and ovarian tissue for cancer patients

Sanada, Y., Harada, M., Kunitomi, C., Kanatani, M., Izumi, G., Hirata, T., Fujii, T., Suzuki, N., Morishige, K. I., Aoki, D., Irahara, M., Tsugawa, K., Tanimoto, M., Nishiyama, H., Hosoi, H., Sugiyama, K., Kawai, A. & Osuga, Y., 2019 10 1, : : Journal of Obstetrics and Gynaecology Research. 45, 10, p. 2021-2028 8 p.

研究成果: Article

Cryopreservation
Ovarian Neoplasms
Oocytes
Embryonic Structures
Neoplasms
Aplastic Anemia
Hematopoietic Stem Cell Transplantation
Cyclophosphamide
Prospective Studies
Transplants
Anastomotic Leak
Esophagectomy
Apgar Score
Survival
Esophageal Neoplasms

Alteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris

Kinoshita, M., Fujimoto, C., Iwasaki, S., Kashio, A., Kikkawa, Y. S., Kondo, K., Okano, H. & Yamasoba, T., 2019 10 25, : : Frontiers in Cellular Neuroscience. 13, 481.

研究成果: Article

公開
Semicircular Ducts
Alopecia
Gentamicins
Regeneration
Guinea Pigs

Altered functional connectivity associated with time discounting in chronic pain

Wakaizumi, K., Jabakhanji, R., Ihara, N., Kosugi, S., Terasawa, Y., Morisaki, H., Ogaki, M. & Baliki, M. N., 2019 12 1, : : Scientific reports. 9, 1, 8154.

研究成果: Article

公開
Chronic Pain
Healthy Volunteers
Prefrontal Cortex
Pain
Brain

Altered perception might be a symptom of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis

Funayama, M., Mizushima, J., Takata, T., Koreki, A. & Mimura, M., 2019 1 1, (Accepted/In press) : : Neurocase.

研究成果: Article

Anti-N-Methyl-D-Aspartate Receptor Encephalitis
Psychiatry
Psychotic Disorders
Time Perception
Confusion
4 引用 (Scopus)

A MST1–FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis

Kim, Y. H., Choi, J., Yang, M. J., Hong, S. P., Lee, C. K., Kubota, Y., Lim, D. S. & Koh, G. Y., 2019 12 1, : : Nature communications. 10, 1, 838.

研究成果: Article

angiogenesis
Cell Polarity
Mitochondria
Endothelial cells
Reactive Oxygen Species
1 引用 (Scopus)

A multiethnic meta-analysis defined the association of rs12946942 with severe adolescent idiopathic scoliosis

Japan Scoliosis Clinical Research Group (JSCRG), 2019 5 1, : : Journal of Human Genetics. 64, 5, p. 493-498 6 p.

研究成果: Article

Scoliosis
Meta-Analysis
Genome-Wide Association Study
Adolescent Development
Computer Simulation
6 引用 (Scopus)

A multimodal (FACILE) classification for optical diagnosis of inflammatory bowel disease associated neoplasia

Iacucci, M., McQuaid, K., Gui, X. S., Iwao, Y., Lethebe, B. C., Lowerison, M., Matsumoto, T., Shivaji, U. N., Smith, S. C. L., Subramanian, V., Uraoka, T., Sanduleanu, S., Ghosh, S. & Kiesslich, R., 2019 1 1, : : Endoscopy. 51, 2, p. 133-141 9 p.

研究成果: Article

Inflammatory Bowel Diseases
Logistic Models
Neoplasms
Inflammation
Colitis
1 引用 (Scopus)

Analysis of DLL3 and ASCL1 in Surgically Resected Small Cell Lung Cancer (HOT1702)

on behalf of Hokkaido Lung Cancer Clinical Study Group, 2019 1 1, : : Oncologist.

研究成果: Article

Small Cell Lung Carcinoma
delta protein
Neuroendocrine Cells
Antibodies

Analysis of skeletal-muscle condition after excessive loading of the lower legs by sequential magnetic resonance imaging

Hata, J., Endo, K., Tsuji, O., Arakawa, S., Sato, M., Yagi, K., Fujiyoshi, K., Okano, H. & Nakamura, M., 2019 1 1, : : Journal of Orthopaedic Science.

研究成果: Article

Leg
Skeletal Muscle
Magnetic Resonance Imaging
Exercise
Anisotropy

Analysis of systemic lupus erythematosus-related interstitial pneumonia: a retrospective multicentre study

Enomoto, N., Egashira, R., Tabata, K., Hashisako, M., Kitani, M., Waseda, Y., Ishizuka, T., Watanabe, S., Kasahara, K., Izumi, S., Shiraki, A., Miyamoto, A., Kishi, K., Kishaba, T., Sugimoto, C., Inoue, Y., Kataoka, K., Kondoh, Y., Tsuchiya, Y., Baba, T. および4人, Sugiura, H., Tanaka, T., Sumikawa, H. & Suda, T., 2019 12 1, : : Scientific reports. 9, 1, 7355.

研究成果: Article

公開
Interstitial Lung Diseases
Systemic Lupus Erythematosus
Multicenter Studies
Retrospective Studies
Tomography

Analysis of Temporobasal Vein with Short Subdural Segment for Anterior Transpetrosal Approach

Tamura, R., Toda, M., Morimoto, Y., Sato, M., Akiyama, T. & Yoshida, K., 2019 1 1, (Accepted/In press) : : World neurosurgery.

研究成果: Article

Veins
Transverse Sinuses
Sigmoid Colon
Temporal Lobe
Phlebography

Analysis of the association between the severity of ocular and systemic pain

Yamanishi, R., Uchino, M., Kawashima, M., Dogru, M., Matsuguma, S. & Tsubota, K., 2019 1 1, : : Ocular Surface.

研究成果: Article

Eye Pain
Eye Diseases
Pain Measurement
Visual Analog Scale
Quality of Life

Analysis of the relapse patterns and risk factors of endometrial cancer following postoperative adjuvant chemotherapy in a phase III randomized clinical trial

Nomura, H., Aoki, D., Susumu, N., Mizuno, M., Nakai, H., Arai, M., Nishio, S., Tokunaga, H., Nakanishi, T., Watanabe, Y., Yaegashi, N., Yokoyama, Y. & Takehara, K., 2019 1 1, (Accepted/In press) : : Gynecologic Oncology.

研究成果: Article

Phase III Clinical Trials
Adjuvant Chemotherapy
Endometrial Neoplasms
Randomized Controlled Trials
Recurrence
3 引用 (Scopus)

Analysis of various tracts of mastoid air cells related to CSF leak after the anterior transpetrosal approach

Tamura, R., Tomio, R., Mohammad, F., Toda, M. & Yoshida, K., 2019 2 1, : : Journal of neurosurgery. 130, 2, p. 360-367 8 p.

研究成果: Article

Mastoid
Temporal Bone
Air
Eustachian Tube
Middle Ear

Analytical performance of a new automated chemiluminescent magnetic immunoassays for soluble PD-1, PD-L1, and CTLA-4 in human plasma

Goto, M., Chamoto, K., Higuchi, K., Yamashita, S., Noda, K., Iino, T., Miura, M., Yamasaki, T., Ogawa, O., Sonobe, M., Date, H., Hamanishi, J., Mandai, M., Tanaka, Y., Chikuma, S., Hatae, R., Muto, M., Minamiguchi, S., Minato, N. & Honjo, T., 2019 12 1, : : Scientific reports. 9, 1, 10144.

研究成果: Article

公開
Immunoassay
Neoplasms
Biomarkers
Immunotherapy
Enzyme-Linked Immunosorbent Assay

A nationwide questionnaire survey of clinic doctors on antimicrobial stewardship in Japan

Gu, Y., Fujitomo, Y., Soeda, H., Nakahama, C., Hasegawa, N., Maesaki, S., Maeda, M., Matsumoto, T., Miyairi, I. & Ohmagari, N., 2019 1 1, (Accepted/In press) : : Journal of Infection and Chemotherapy.

研究成果: Article

Japan
Common Cold
Bronchitis
Macrolides
Prescriptions
1 引用 (Scopus)

Anatomical and surgical evaluation of the common marmoset as an animal model in hearing research

Kurihara, S., Fujioka, M., Hata, J., Yoshida, T., Hirabayashi, M., Yamamoto, Y., Ogawa, K., Kojima, H. & Okano, H. J., 2019 6 3, : : Frontiers in Neuroanatomy. 13, 60.

研究成果: Article

公開
Callithrix
Inner Ear
Hearing
Animal Models
Diffusion Tensor Imaging
公開
Induced Pluripotent Stem Cells
Vibration
Karyotype
Enzymes

A neonatal case of HDR syndrome and a vascular ring with a novel GATA3 mutation

Kusakawa, M., Sato, T., Hosoda, A., Araki, E., Matsuzaki, Y., Yamashita, Y., Ishihara, J., Inagaki, Y., Uchida, N., Ishii, T. & Hasegawa, T., 2019 12 1, : : Human Genome Variation. 6, 1, 55.

研究成果: Article

公開
Blood Vessels
Genes
Mutation
Genetic Databases
Haploinsufficiency

A new training method for velopharyngeal dysfunction: Self-inhalation for hypernasality

Kobayashi, R., Tsunoda, K., Takazawa, M., Ueha, R., Hosoya, M., Fujimaki, Y., Nito, T. & Yamasoba, T., 2019 1 1, (Accepted/In press) : : Auris Nasus Larynx.

研究成果: Article

Nose
Inhalation
Surgical Instruments
Rehabilitation
Dysarthria
Distraction Osteogenesis
Equipment and Supplies
Control Groups
Craniosynostoses
Hoof and Claw

Annual report of Reproductive Endocrinology Committee, Japan Society of Obstetrics and Gynecology, 2019

Osuga, Y., Akira, S., Irahara, M., Iwase, A., Katagiri, Y., Kugu, K., Terada, Y., Maruyama, T. & Fujiwara, H., 2019 1 1, (Accepted/In press) : : Journal of Obstetrics and Gynaecology Research.

研究成果: Article

Annual Reports
Endocrinology
Gynecology
Obstetrics
Fertility
1 引用 (Scopus)

A novel cell-free, non-fluorescent method to measure lox-1-binding activity corresponding to the functional activity of hdl

Kakino, A., Usami, Y., Horiuchi, S., Fujita, Y., Kotani, K., Chen, C. H., Okamura, T. & Sawamura, T., 2019 1 1, : : Journal of atherosclerosis and thrombosis. 26, 11, p. 947-958 12 p.

研究成果: Article

公開
HDL Lipoproteins
Immunosorbents
Assays
Enzyme-Linked Immunosorbent Assay
Fusion reactions
1 引用 (Scopus)
Four-Dimensional Computed Tomography
Veins
Brain
Digital Subtraction Angiography
Intracranial Aneurysm
2 引用 (Scopus)
公開
ischemia
hypoxia
inhibitors
Reperfusion
Screening

A Novel Laser Fiberscope for Simultaneous Imaging and Phototherapy of Peripheral Lung Cancer

Kinoshita, T., Effat, A., Gregor, A., Inage, T., Ishiwata, T., Motooka, Y., Ujiie, H., Wilson, B. C., Zheng, G., Weersink, R., Asamura, H. & Yasufuku, K., 2019 1 1, : : Chest.

研究成果: Article

Phototherapy
Lung Neoplasms
Lasers
Therapeutics
Bronchoscopes

A novel missense PTEN mutation identified in a patient with macrocephaly and developmental delay

Ueno, Y., Enokizono, T., Fukushima, H., Ohto, T., Imagawa, K., Tanaka, M., Sakai, A., Suzuki, H., Uehara, T., Takenouchi, T., Kosaki, K. & Takada, H., 2019 12 1, : : Human Genome Variation. 6, 1, 25.

研究成果: Article

公開
Megalencephaly
Phosphoric Monoester Hydrolases
Multiple Hamartoma Syndrome
Mutation
Tumors
公開
Motor Vehicles
Emergencies
Surgery
laparotomy
Thoracotomy
2 引用 (Scopus)
公開
Withholding Treatment
Smoking Cessation
Carbon Monoxide
Clinical Protocols
Randomized Controlled Trials

Antigen-driven selection of antibodies against SSA, SSB and the centromere 'complex', including a novel antigen, MIS12 complex, in human salivary glands

Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., Kato, S., Tsunoda, K., Arase, H. & Takeuchi, T., 2019 1 1, (Accepted/In press) : : Annals of the rheumatic diseases.

研究成果: Article

公開
Centromere
Salivary Glands
Autoantibodies
Antigens
Anti-Idiotypic Antibodies
Antipsychotic Agents
Schizophrenia
Maintenance
Guidelines
MEDLINE

Aortic stenosis with right-sided aortic arch treated with transfemoral aortic valve implantation

Yashima, F., Hayashida, K., Munakata, M., Arai, T., Shimizu, H. & Fukuda, K., 2019 1 25, : : Cardiovascular Intervention and Therapeutics. 34, 1, p. 70-71 2 p.

研究成果: Article

Aortic Valve Stenosis
Thoracic Aorta
Aortic Valve
Transcatheter Aortic Valve Replacement

A phase 3 study of nivolumab in previously treated advanced gastric or gastroesophageal junction cancer (ATTRACTION-2): 2-year update data

Chen, L. T., Satoh, T., Ryu, M. H., Chao, Y., Kato, K., Chung, H. C., Chen, J. S., Muro, K., Kang, W. K., Yeh, K. H., Yoshikawa, T., Oh, S. C., Bai, L. Y., Tamura, T., Lee, K. W., Hamamoto, Y., Kim, J. G., Chin, K., Oh, D. Y., Minashi, K. および5人, Cho, J. Y., Tsuda, M., Sameshima, H., Kang, Y. K. & Boku, N., 2019 1 1, (Accepted/In press) : : Gastric Cancer.

研究成果: Article

公開
Esophagogastric Junction
Stomach
Survival
Neoplasms
Placebos

A Phase II Study of Regorafenib With a Lower Starting Dose in Patients With Metastatic Colorectal Cancer: Exposure–Toxicity Analysis of Unbound Regorafenib and Its Active Metabolites (RESET Trial)

Suzuki, T., Sukawa, Y., Imamura, C. K., Masuishi, T., Satake, H., Kumekawa, Y., Funakoshi, S., Kotaka, M., Horie, Y., Kawai, S., Okuda, H., Terazawa, T., Kondoh, C., Kato, K., Yoshimura, K., Ishikawa, H., Hamamoto, Y., Boku, N., Takaishi, H. & Kanai, T., 2019 1 1, (Accepted/In press) : : Clinical Colorectal Cancer.

研究成果: Article

Colorectal Neoplasms
regorafenib
1 引用 (Scopus)

A phase II trial of induction of erlotinib followed by cytotoxic chemotherapy for EGFR mutation-positive non-squamous non-small cell lung cancer patients

Tani, T., Naoki, K., Yasuda, H., Arai, D., Ishioka, K., Ohgino, K., Yoda, S., Nakayama, S., Satomi, R., Terai, H., Ikemura, S., Sato, T. & Soejima, K., 2019 1 1, (Accepted/In press) : : Cancer Chemotherapy and Pharmacology.

研究成果: Article

Chemotherapy
Non-Small Cell Lung Carcinoma
Cells
Drug Therapy
Mutation
公開
Feasibility Studies
Cognitive Therapy
Japan
Anxiety
Students
12 引用 (Scopus)

APOE Alleles and Extreme Human Longevity

Sebastiani, P., Gurinovich, A., Nygaard, M., Sasaki, T., Sweigart, B., Bae, H., Andersen, S. L., Villa, F., Atzmon, G., Christensen, K., Arai, Y., Barzilai, N., Puca, A., Christiansen, L., Hirose, N. & Perls, T. T., 2019 1 1, : : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 1, p. 44-51 8 p.

研究成果: Article

Alleles
Genotype
Population
New England
Retirement
2 引用 (Scopus)
Radiosurgery
Neoplasm Metastasis
Brain
Neoplasms
Survival
7 引用 (Scopus)
公開
spinal cord injuries
Hepatocyte Growth Factor
Spinal Cord Injuries
roads
Rats
4 引用 (Scopus)

Application of high-performance magnetic nanobeads to biological sensing devices

Kabe, Y., Sakamoto, S., Hatakeyama, M., Yamaguchi, Y., Suematsu, M., Itonaga, M. & Handa, H., 2019 1 1, (Accepted/In press) : : Analytical and Bioanalytical Chemistry.

研究成果: Article

Exosomes
Equipment and Supplies
Technology
Immunoassay
Drug Receptors
公開
Metabolomics
Epidemiologic Studies
Atherosclerosis
Cardiovascular Diseases
Metabolites