生理学

1985

Disorders in myelination in the twitcher mutant: Immunohistochemical and biochemical studies

Mikoshiba, K., Fujishiro, M., Kohsaka, S., Okano, H., Takamatsu, K. & Tsukada, Y., 1985 8月, In: Neurochemical Research. 10, 8, p. 1129-1141 13 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Molecular Genetic Analysis of Myelin‐Deficient Mice: Shiverer Mutant Mice Show Deletion in Gene(s) Coding for Myelin Basic Protein

Kimura, M., Inoko, H., Katsuki, M., Ando, A., Sato, T., Hirose, T., Takashima, H., Inayama, S., Okano, H., Takamatsu, K., Mikoshiba, K., Tsukada, Y. & Watanabe, I., 1985 3月, In: Journal of Neurochemistry. 44, 3, p. 692-696 5 p.

研究成果: Article › 査読

70 被引用数 (Scopus)

1988

A case of acute bacterial endocarditis with severe anterior uveitis

Andou, Y., Suzuki, S. & Okano, H., 1988 1月 1, In: Folia Ophthalmologica Japonica. 39, 12, p. 2168-2173 6 p.

研究成果: Article › 査読

1995

Ca²⁺ release from Ca²⁺ stores, particularly from ryanodine-sensitive Ca²⁺ stores, is required for the induction of LTD in cultured cerebellar Purkinje cells

Kohda, K., Inoue, T. & Mikoshiba, K., 1995 1月 1, In: Journal of Neurophysiology. 74, 5, p. 2184-2188 5 p.

研究成果: Article › 査読

63 被引用数 (Scopus)

1997

Phosphorylation-dependent regulation of N-methyl-D-aspartate receptors by calmodulin

Hisatsune, C., Umemori, H., Inoue, T., Michikawa, T., Kohda, K., Mikoshiba, K. & Yamamoto, T., 1997 8月 15, In: Journal of Biological Chemistry. 272, 33, p. 20805-20810 6 p.

研究成果: Article › 査読

110 被引用数 (Scopus)

1999

Interaction of the C-terminal domain of δ glutamate receptor with spectrin in the dendritic spines of cultured Purkinje cells

Hirai, H. & Matsuda, S., 1999 9月 1, In: Neuroscience Research. 34, 4, p. 281-287 7 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Role of synaptotagmin, a Ca²⁺ and inositol polyphosphate binding protein, in neurotransmitter release and neurite outgrowth

Mikoshiba, K., Fukuda, M., Ibata, K., Kabayama, H. & Mizutani, A., 1999 4月, In: Chemistry and Physics of Lipids. 98, 1-2, p. 59-67 9 p.

研究成果: Article › 査読

43 被引用数 (Scopus)

The clustering of NMDA receptor NR1 subunit is regulated by the interaction between the C-terminal exon cassettes and the cytoskeleton

Matsuda, S. & Hirai, H., 1999 8月 1, In: Neuroscience Research. 34, 3, p. 157-163 7 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

2000

Synaptotagmin IV is present at the Golgi and distal parts of neurites

Ibata, K., Fukuda, M., Hamada, T., Kabayama, H. & Mikoshiba, K., 2000 1月 29, In: Journal of Neurochemistry. 74, 2, p. 518-526 9 p.

研究成果: Article › 査読

65 被引用数 (Scopus)

SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms

Mizutani, A., Fukuda, M., Ibata, K., Shiraishi, Y. & Mikoshiba, K., 2000 3月 31, In: Journal of Biological Chemistry. 275, 13, p. 9823-9831 9 p.

研究成果: Article › 査読

70 被引用数 (Scopus)

2001

Activation of murine cytomegalovirus immediate-early promoter in cerebral ventricular zone and glial progenitor cells in transgenic mice

Li, R. Y., Baba, S., Kosugi, I., Arai, Y., Kawasaki, H., Shinmura, Y., Sakakibara, S. I., Okano, H. & Tsutsui, Y., 2001, In: Glia. 35, 1, p. 41-52 12 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Asymmetric inheritance of radial glial fibers by cortical neurons

Miyata, T., Kawaguchi, A., Okano, H. & Ogawa, M., 2001 9月 13, In: Neuron. 31, 5, p. 727-741 15 p.

研究成果: Article › 査読

705 被引用数 (Scopus)

A unique spacer domain of synaptotagmin IV is essential for Golgi localization

Fukuda, M., Ibata, K. & Mikoshiba, K., 2001, In: Journal of Neurochemistry. 77, 3, p. 730-740 11 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Brain from bone: Efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent

Kohyama, J., Abe, H., Shimazaki, T., Koizumi, A., Nakashima, K., Gojo, S., Taga, T., Okano, H., Hata, J. I. & Umezawa, A., 2001 10月, In: Differentiation. 68, 4-5, p. 235-244 10 p.

研究成果: Article › 査読

276 被引用数 (Scopus)

Direct isolation of committed neuronal progenitor cells from transgenic mice coexpressing spectrally distinct fluorescent protemins regulated by stage-specific neural promoters

Sawamoto, K., Yamamoto, A., Kawaguchi, A., Yamaguchi, M., Mori, K., Goldman, S. A. & Okano, H., 2001 8月 1, In: Journal of neuroscience research. 65, 3, p. 220-227 8 p.

研究成果: Article › 査読

57 被引用数 (Scopus)

Expression of mouse igf2 mRNA-binding protein 3 and its implications for the developing central nervous system

Mori, H., Sakakibara, S. I., Imai, T., Nakamura, Y., Iijima, T., Suzuki, A., Yuasa, Y., Takeda, M. & Okano, H., 2001 4月 15, In: Journal of neuroscience research. 64, 2, p. 132-143 12 p.

研究成果: Article › 査読

46 被引用数 (Scopus)

Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene

Sawamoto, K., Nakao, N., Kakishita, K., Ogawa, Y., Toyama, Y., Yamamoto, A., Yamaguchi, M., Mori, K., Goldman, S. A., Itakura, T. & Okano, H., 2001 6月 1, In: Journal of Neuroscience. 21, 11, p. 3895-3903 9 p.

研究成果: Article › 査読

Open Access

184 被引用数 (Scopus)

High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain

Keyoung, H. M., Roy, N. S., Benraiss, A., Louissaint, A., Suzuki, A., Hashimoto, M., Rashbaum, W. K., Okano, H. & Goldman, S. A., 2001, In: Nature Biotechnology. 19, 9, p. 843-850 8 p.

研究成果: Article › 査読

145 被引用数 (Scopus)

Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis

Kishi, N., Tang, Z., Maeda, Y., Hirai, A., Mo, R., Ito, M., Suzuki, S., Nakao, K., Kinoshita, T., Kadesch, T., Hui, C. C., Artavanis-Tsakonas, S., Okano, H. & Matsuno, K., 2001 2月 1, In: International Journal of Developmental Neuroscience. 19, 1, p. 21-35 15 p.

研究成果: Article › 査読

77 被引用数 (Scopus)

Musashi1, an evolutionarily conserved neural RNA-binding protein, is a versatile marker of human glioma cells in determining their cellular origin, malignancy, and proliferative activity

Kanemura, Y., Yamasaki, M., Kanemura, Y., Mori, K., Fujikawa, H., Hayashi, H., Nakano, A., Matsumoto, T., Tamura, K., Arita, N., Sakakibara, S. I., Ohnishi, T., Fushiki, S., Nakamura, Y., Imai, T. & Okano, H., 2001, In: Differentiation. 68, 2-3, p. 141-152 12 p.

研究成果: Article › 査読

109 被引用数 (Scopus)

Neural stem cells: The basic biology and prospects for brain repair

Okano, H., 2001 12月 1, In: Clinical Neurology. 41, 12, p. 1036-1040 5 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

RNA-binding protein Musashi2: Developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS

Sakakibara, S. I., Nakamura, Y., Satoh, H. & Okano, H., 2001 10月 15, In: Journal of Neuroscience. 21, 20, p. 8091-8107 17 p.

研究成果: Article › 査読

Open Access

182 被引用数 (Scopus)

Role of Deltex-1 as a Transcriptional Regulator Downstream of the Notch Receptor

Yamamoto, N., Yamamoto, S. I., Inagaki, F., Kawaichi, M., Fukamizu, A., Kishi, N., Matsuno, K., Nakamura, K., Weinmaster, G., Okano, H. & Nakafuku, M., 2001 11月 30, In: Journal of Biological Chemistry. 276, 48, p. 45031-45040 10 p.

研究成果: Article › 査読

159 被引用数 (Scopus)

The ciliary neurotrophic factor/leukemia inhibitory factor/gp130 receptor complex operates in the maintenance of mammalian forebrain neural stem cells

Shimazaki, T., Shingo, T. & Weiss, S., 2001 10月 1, In: Journal of Neuroscience. 21, 19, p. 7642-7653 12 p.

研究成果: Article › 査読

Open Access

252 被引用数 (Scopus)

The neural RNA-binding protein musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA

Imai, T., Tokunaga, A., Yoshida, T., Hashimoto, M., Mikoshiba, K., Weinmaster, G., Nakafuku, M. & Okano, H., 2001 6月, In: Molecular and cellular biology. 21, 12, p. 3888-3900 13 p.

研究成果: Article › 査読

365 被引用数 (Scopus)

Translational repression determines a neuronal potential in Drosophila asymmetric cell division

Okabe, M., Imai, T., Kurusu, M., Hiromi, Y. & Okano, H., 2001 5月 3, In: Nature. 411, 6833, p. 94-98 5 p.

研究成果: Article › 査読

167 被引用数 (Scopus)

Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons

Sawamoto, K., Nakao, N., Kobayashi, K., Matsushita, N., Takahashi, H., Kakishita, K., Yamamoto, A., Yoshizaki, T., Terashima, T., Murakami, F., Itakura, T. & Okano, H., 2001 5月 22, In: Proceedings of the National Academy of Sciences of the United States of America. 98, 11, p. 6423-6428 6 p.

研究成果: Article › 査読

191 被引用数 (Scopus)

2002

Differential expression of Musashi1 and nestin in the adult rat hippocampus after ischemia

Yagita, Y., Kitagawa, K., Sasaki, T., Miyata, T., Okano, H., Hori, M. & Matsumoto, M., 2002 9月 15, In: Journal of neuroscience research. 69, 6, p. 750-756 7 p.

研究成果: Article › 査読

46 被引用数 (Scopus)

Evaluation of in vitro proliferative activity of human fetal neural stem/progenitor cells using indirect measurements of viable cells based on cellular metabolic activity

Kanemura, Y., Mori, H., Kobayashi, S., Islam, O., Kodama, E., Yamamoto, A., Nakanishi, Y., Arita, N., Yamasaki, M., Okano, H., Hara, M. & Miyake, J., 2002 9月 15, In: Journal of neuroscience research. 69, 6, p. 869-879 11 p.

研究成果: Article › 査読

Open Access

122 被引用数 (Scopus)

Expression of the Musashi1 gene encoding the RNA-binding protein in human hepatoma cell lines

Shu, H. J., Saito, T., Watanabe, H., Ito, J. I., Takeda, H., Okano, H. & Kawata, S., 2002, In: Biochemical and Biophysical Research Communications. 293, 1, p. 150-154 5 p.

研究成果: Article › 査読

56 被引用数 (Scopus)

Flow cytometric analysis of neural stem cells in the developing and adult mouse brain

Murayama, A., Matsuzaki, Y., Kawaguchi, A., Shimazaki, T. & Okano, H., 2002 9月 15, In: Journal of neuroscience research. 69, 6, p. 837-847 11 p.

研究成果: Article › 査読

107 被引用数 (Scopus)

Isolation and transplantation of dopaminergic neurons and neural stem cells

Okano, H., Yoshizaki, T., Shimazaki, T. & Sawamoto, K., 2002 10月 1, In: Parkinsonism and Related Disorders. 9, 1, p. 23-28 6 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Musashi: A translational regulator of cell fate

Okano, H., Imai, T. & Okabe, M., 2002 4月 1, In: Journal of Cell Science. 115, 7, p. 1355-1359 5 p.

研究成果: Article › 査読

285 被引用数 (Scopus)

Nestin enhancer requirements for expression in normal and injured adult CNS

Johansson, C. B., Lothian, C., Molin, M., Okano, H. & Lendahl, U., 2002 9月 15, In: Journal of neuroscience research. 69, 6, p. 784-794 11 p.

研究成果: Article › 査読

45 被引用数 (Scopus)

Reaper-mediated inhibition of DIAP1-induced DTRAF1 degradation results in activation of JNK in Drosophila

Kuranaga, E., Kanuka, H., Igaki, T., Sawamoto, K., Ichijo, H., Okano, H. & Miura, M., 2002 9月, In: Nature Cell Biology. 4, 9, p. 705-710 6 p.

研究成果: Article › 査読

114 被引用数 (Scopus)

Regulation of tau RNA maturation by thyroid hormone is mediated by the neural RNA-binding protein musashi-1

Cuadrado, A., García-Fernández, L. F., Imai, T., Okano, H. & Muñoz, A., 2002, In: Molecular and Cellular Neuroscience. 20, 2, p. 198-210 13 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

RNA-binding protein Musashi family: Roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation

Sakakibara, S. I., Nakamura, Y., Yoshida, T., Shibata, S., Koike, M., Takano, H., Ueda, S., Uchiyama, Y., Noda, T. & Okano, H., 2002 11月 12, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 23, p. 15194-15199 6 p.

研究成果: Article › 査読

271 被引用数 (Scopus)

rugose (rg), a drosophila a kinase anchor protein, is required for retinal pattern formation and interacts genetically with multiple signaling pathways

Shamloula, H. K., Mbogho, M. P., Pimentel, A. C., Chrzanowska-Lightowlers, Z. M. A., Hyatt, V., Okano, H. & Venkatesh, T. R., 2002 7月 10, In: Genetics. 161, 2, p. 693-710 18 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila

Hirota, Y., Sawamoto, K. & Okano, H., 2002 12月 1, In: Gene Expression Patterns. 2, 3-4, p. 323-327 5 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

tincar encodes a novel transmembrane protein expressed in the Tinman-expressing cardioblasts of Drosophila

Hirota, Y., Sawamoto, K. & Okano, H., 2002 12月, In: Mechanisms of Development. 119, SUPPL. 1, p. S279-S283

研究成果: Article › 査読

3 被引用数 (Scopus)

Transplantation of in vitro-expanded fetal neural progenitor cells results in neurogenesis and functional recovery after spinal cord contusion injury in adult rats

Ogawa, Y., Sawamoto, K., Miyata, T., Miyao, S., Watanabe, M., Nakamura, M., Bregman, B. S., Koike, M., Uchiyama, Y., Toyama, Y. & Okano, H., 2002 9月 15, In: Journal of neuroscience research. 69, 6, p. 925-933 9 p.

研究成果: Article › 査読

438 被引用数 (Scopus)

Upregulation of Akt phosphorylation at the early stage of middle cerebral artery occlusion in mice

Shibata, M., Yamawaki, T., Sasaki, T., Hattori, H., Hamada, J., Fukuuchi, Y., Okano, H. & Miura, M., 2002 6月 28, In: Brain Research. 942, 1-2, p. 1-10 10 p.

研究成果: Article › 査読

64 被引用数 (Scopus)

Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for eiger signaling

Kanda, H., Igaki, T., Kanuka, H., Yagi, T. & Miura, M., 2002 8月 9, In: Journal of Biological Chemistry. 277, 32, p. 28372-28375 4 p.

研究成果: Article › 査読

141 被引用数 (Scopus)

2003

Biology and clinical application of neural stem cells

Shimazaki, T., 2003 12月 30, In: Hormone Research. 60, SUPPL. 3, p. 1-9 9 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine

Kayahara, T., Sawada, M., Takaishi, S., Fukui, H., Seno, H., Fukuzawa, H., Suzuki, K., Hiai, H., Kageyama, R., Okano, H. & Chiba, T., 2003 1月 30, In: FEBS Letters. 535, 1-3, p. 131-135 5 p.

研究成果: Article › 査読

264 被引用数 (Scopus)

Caspase-mediated oligodendrocyte cell death in the pathogenesis of autoimmune demyelination

Hisahara, S., Okano, H. & Miura, M., 2003 8月 1, In: Neuroscience Research. 46, 4, p. 387-397 11 p.

研究成果: Article › 査読

57 被引用数 (Scopus)

Cortical and striatal expression of tyrosine hydroxylase mRNA in neonatal and adult mice

Baker, H., Kobayashi, K., Okano, H. & Saino-Saito, S., 2003 10月, In: Cellular and Molecular Neurobiology. 23, 4-5, p. 507-518 12 p.

研究成果: Article › 査読

41 被引用数 (Scopus)

Cyclooxygenase-2 is involved in increased proliferation of neuronal progenitor cells in the ischemic mouse hippocampus

Sasaki, T., Kitagawa, K., Sugiura, S., Omura-Matsuoka, E., Tanaka, S., Yagita, Y., Okano, H., Matsumoto, M. & Hori, M., 2003 6月 1, In: International Congress Series. 1252, C, p. 445-450 6 p.

研究成果: Article › 査読

Cytosol-endoplasmic reticulum interplay by Sec61α translocon in polyglutamine-mediated neurotoxicity in Drosophila

Kanuka, H., Kuranaga, E., Hiratou, T., Igaki, T., Nelson, B., Okano, H. & Miura, M., 2003 9月 30, In: Proceedings of the National Academy of Sciences of the United States of America. 100, 20, p. 11723-11728 6 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Differential proliferative response in the postischemic hippocampus, temporal cortex, and olfactory bulb of young adult macaque monkeys

Tonchev, A. B., Yamashima, T., Zhao, L. & Okano, H., 2003 5月 1, In: Glia. 42, 3, p. 209-224 16 p.

研究成果: Article › 査読

57 被引用数 (Scopus)

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