生理学

2017

Evaluation of the immunogenicity of human iPS cell-derived neural stem/progenitor cells in vitro

Ozaki, M., Iwanami, A., Nagoshi, N., Kohyama, J., Itakura, G., Iwai, H., Nishimura, S., Nishiyama, Y., Kawabata, S., Sugai, K., Iida, T., Matsubayashi, K., Isoda, M., Kashiwagi, R., Toyama, Y., Matsumoto, M., Okano, H. & Nakamura, M., 2017 3月 1, In: Stem Cell Research. 19, p. 128-138 11 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease

Shiba-Fukushima, K., Ishikawa, K. I., Inoshita, T., Izawa, N., Takanashi, M., Sato, S., Onodera, O., Akamatsu, W., Okano, H., Imai, Y. & Hattori, N., 2017 8月 15, In: Human molecular genetics. 26, 16, p. 3172-3185 14 p., ddx201.

研究成果: Article › 査読

31 被引用数 (Scopus)

Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives

Itakura, G., Kawabata, S., Ando, M., Nishiyama, Y., Sugai, K., Ozaki, M., Iida, T., Ookubo, T., Kojima, K., Kashiwagi, R., Yasutake, K., Nakauchi, H., Miyoshi, H., Nagoshi, N., Kohyama, J., Iwanami, A., Matsumoto, M., Nakamura, M. & Okano, H., 2017 3月 14, In: Stem cell reports. 8, 3, p. 673-684 12 p.

研究成果: Article › 査読

Open Access

63 被引用数 (Scopus)

Generation of induced pluripotent stem cells and neural stem/progenitor cells from newborns with Spina bifida aperta

Bamba, Y., Nonaka, M., Sasaki, N., Shofuda, T., Kanematsu, D., Suemizu, H., Higuchi, Y., Pooh, R. K., Kanemura, Y., Okano, H. & Yamasaki, M., 2017 12月 1, In: Asian Spine Journal. 11, 6, p. 870-879 10 p.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Generation of neural cells using iPSCs from sleep bruxism patients with 5-HT2A polymorphism

Hoashi, Y., Okamoto, S., Abe, Y., Matsumoto, T., Tanaka, J., Yoshida, Y., Imaizumi, K., Mishima, K., Akamatsu, W., Okano, H. & Baba, K., 2017 7月, In: Journal of Prosthodontic Research. 61, 3, p. 242-250 9 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Glutamate transporter GLAST controls synaptic wrapping by Bergmann glia and ensures proper wiring of Purkinje cells

Miyazaki, T., Yamasaki, M., Hashimoto, K., Kohda, K., Yuzaki, M., Shimamoto, K., Tanaka, K., Kano, M. & Watanabe, M., 2017 7月 11, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 28, p. 7438-7443 6 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Hypoxia Epigenetically Confers Astrocytic Differentiation Potential on Human Pluripotent Cell-Derived Neural Precursor Cells

Yasui, T., Uezono, N., Nakashima, H., Noguchi, H., Matsuda, T., Noda-Andoh, T., Okano, H. & Nakashima, K., 2017 6月 6, In: Stem cell reports. 8, 6, p. 1743-1756 14 p.

研究成果: Article › 査読

Open Access

20 被引用数 (Scopus)

Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation

Someya, K., Nakatsukasa, H., Ito, M., Kondo, T., Tateda, K. I., Akanuma, T., Koya, I., Sanosaka, T., Kohyama, J., Tsukada, Y. I., Takamura-Enya, T. & Yoshimura, A., 2017 8月 1, In: International immunology. 29, 8, p. 365-375 11 p., dxx049.

研究成果: Article › 査読

42 被引用数 (Scopus)

Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells

Veraitch, O., Mabuchi, Y., Matsuzaki, Y., Sasaki, T., Okuno, H., Tsukashima, A., Amagai, M., Okano, H. & Ohyama, M., 2017 2月 21, In: Scientific reports. 7, 42777.

研究成果: Article › 査読

Open Access

26 被引用数 (Scopus)

In vivo microscopic voxel-based morphometry with a brain template to characterize strainspecific structures in the mouse brain

Hikishima, K., Komaki, Y., Seki, F., Ohnishi, Y., Okano, H. J. & Okano, H., 2017, In: Scientific reports. 7, 1, 85.

研究成果: Article › 査読

Open Access

26 被引用数 (Scopus)

Involvement of the septo-hippocampal cholinergic pathway in association with septal acetylcholinesterase upregulation in a mouse model of tauopathy

Hara, Y., Motoi, Y., Hikishima, K., Mizuma, H., Onoe, H., Matsumoto, S. E., Elahi, M., Okano, H., Aoki, S. & Hattori, N., 2017 1月 1, In: Current Alzheimer Research. 14, 1, p. 94-103 10 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells

Itakura, G., Ozaki, M., Nagoshi, N., Kawabata, S., Nishiyama, Y., Sugai, K., Iida, T., Kashiwagi, R., Ookubo, T., Yastake, K., Matsubayashi, K., Kohyama, J., Iwanami, A., Matsumoto, M., Nakamura, M. & Okano, H., 2017 12月 1, In: Scientific reports. 7, 1, 12996.

研究成果: Article › 査読

13 被引用数 (Scopus)

Mapping orbitofrontal-limbic maturation in non-human primates: A longitudinal magnetic resonance imaging study

Uematsu, A., Hata, J., Komaki, Y., Seki, F., Yamada, C., Okahara, N., Kurotaki, Y., Sasaki, E. & Okano, H., 2017 12月, In: NeuroImage. 163, p. 55-67 13 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

MTCL1 plays an essential role in maintaining Purkinje neuron axon initial segment

Satake, T., Yamashita, K., Hayashi, K., Miyatake, S., Tamura-Nakano, M., Doi, H., Furuta, Y., Shioi, G., Miura, E., Takeo, Y. H., Yoshida, K., Yahikozawa, H., Matsumoto, N., Yuzaki, M. & Suzuki, A., 2017 5月 2, In: EMBO Journal. 36, 9, p. 1227-1242 16 p.

研究成果: Article › 査読

Open Access

25 被引用数 (Scopus)

Muscle architectural properties in the common marmoset (Callithrix jacchus)

Ogihara, N., Oishi, M., Kanai, R., Shimada, H., Kondo, T., Yoshino-Saito, K., Ushiba, J. & Okano, H., 2017 7月 1, In: Primates. 58, 3, p. 461-472 12 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Naive-like ESRRB⁺ iPSCs with the Capacity for Rapid Neural Differentiation

Kisa, F., Shiozawa, S., Oda, K., Yoshimatsu, S., Nakamura, M., Koya, I., Kawai, K., Suzuki, S. & Okano, H., 2017 12月 12, In: Stem cell reports. 9, 6, p. 1825-1838 14 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Neural differentiation of human embryonic stem cells induced by the transgene-mediated overexpression of single transcription factors

Matsushita, M., Nakatake, Y., Arai, I., Ibata, K., Kohda, K., Goparaju, S. K., Murakami, M., Sakota, M., Chikazawa-Nohtomi, N., Ko, S. B. H., Kanai, T., Yuzaki, M. & Ko, M. S. H., 2017 8月 19, In: Biochemical and Biophysical Research Communications. 490, 2, p. 296-301 6 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Plasticity and regeneration in the injured spinal cord after cell transplantation therapy

Nori, S., Nakamura, M. & Okano, H., 2017, (Accepted/In press) In: Progress in Brain Research.

研究成果: Article › 査読

18 被引用数 (Scopus)

q-Space Myelin Map imaging for longitudinal analysis of demyelination and remyelination in multiple sclerosis patients treated with fingolimod: A preliminary study

Tanikawa, M., Nakahara, J., Hata, J., Suzuki, S., Fujiyoshi, K., Fujiwara, H., Momoshima, S., Jinzaki, M., Nakamura, M., Okano, H., Takahashi, S. & Suzuki, N., 2017 2月 15, In: Journal of the Neurological Sciences. 373, p. 352-357 6 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Rapid differentiation of human pluripotent stem cells into functional neurons by mRNAs encoding transcription factors

Goparaju, S. K., Kouda, K., Ibata, K., Soma, A., Nakatake, Y., Akiyama, T., Wakabayashi, S., Matsushita, M., Sakota, M., Kimura, H., Yuzaki, M., Ko, S. & Ko, M. S. H., 2017 2月 13, In: Scientific reports. 7, 42367.

研究成果: Article › 査読

52 被引用数 (Scopus)

Reactive astrocytes function as phagocytes after brain ischemia via ABCA1-mediated pathway

Morizawa, Y. M., Hirayama, Y., Ohno, N., Shibata, S., Shigetomi, E., Sui, Y., Nabekura, J., Sato, K., Okajima, F., Takebayashi, H., Okano, H. & Koizumi, S., 2017 12月 1, In: Nature communications. 8, 1, 28.

研究成果: Article › 査読

162 被引用数 (Scopus)

Regulation of RhoA by STAT3 coordinates glial scar formation

Renault-Mihara, F., Mukaino, M., Shinozaki, M., Kumamaru, H., Kawase, S., Baudoux, M., Ishibashi, T., Kawabata, S., Nishiyama, Y., Sugai, K., Yasutake, K., Okada, S., Nakamura, M. & Okano, H., 2017, In: Journal of Cell Biology. 216, 8, p. 2533-2550 18 p.

研究成果: Article › 査読

Open Access

52 被引用数 (Scopus)

Regulation of Sema3c and the Interaction between Cardiac Neural Crest and Second Heart Field during Outflow Tract Development

Kodo, K., Shibata, S., Miyagawa-Tomita, S., Ong, S. G., Takahashi, H., Kume, T., Okano, H., Matsuoka, R. & Yamagishi, H., 2017 12月 1, In: Scientific reports. 7, 1, 6771.

研究成果: Article › 査読

27 被引用数 (Scopus)

RNA Sequencing Analysis Reveals Interactions between Breast Cancer or Melanoma Cells and the Tissue Microenvironment during Brain Metastasis

Sato, R., Nakano, T., Hosonaga, M., Sampetrean, O., Harigai, R., Sasaki, T., Koya, I., Okano, H., Kudoh, J., Saya, H. & Arima, Y., 2017, In: BioMed Research International. 2017, 8032910.

研究成果: Article › 査読

21 被引用数 (Scopus)

Signaling Pathways Relevant to Nerve Growth Factor-induced Upregulation of Transient Receptor Potential M8 Expression

Kayama, Y., Shibata, M., Takizawa, T., Ibata, K., Nakahara, J., Shimizu, T., Toriumi, H., Yuzaki, M. & Suzuki, N., 2017 12月 26, In: Neuroscience. 367, p. 178-188 11 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Skin-derived precursors as a source of progenitors for corneal endothelial regeneration

Inagaki, E., Hatou, S., Higa, K., Yoshida, S., Shibata, S., Okano, H., Tsubota, K. & Shimmura, S., 2017 3月, In: Stem Cells Translational Medicine. 6, 3, p. 788-798 11 p.

研究成果: Article › 査読

Open Access

26 被引用数 (Scopus)

SOX10 expression as well as BRAF and GNAQ/11 mutations distinguish pigmented ciliary epithelium neoplasms from uveal melanomas

Mori, T., Sukeda, A., Sekine, S., Shibata, S., Ryo, E., Okano, H., Suzuki, S. & Hiraoka, N., 2017 10月, In: Investigative Ophthalmology and Visual Science. 58, 12, p. 5445-5451 7 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Sox21 deletion in mice causes postnatal growth deficiency without physiological disruption of hypothalamic-pituitary endocrine axes

Cheung, L. Y. M., Okano, H. & Camper, S. A., 2017 1月 5, In: Molecular and Cellular Endocrinology. 439, p. 213-223 11 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Technical feasibility of visualizing myenteric plexus using confocal laser endomicroscopy

Kobayashi, M., Sumiyama, K., Shimojima, N., Ieiri, S., Okano, H., Kamba, S., Fujimura, T., Hirobe, S., Kuroda, T. & Takahashi-Fujigasaki, J., 2017 9月, In: Journal of Gastroenterology and Hepatology (Australia). 32, 9, p. 1604-1610 7 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

The Semaphorin 3A inhibitor SM-345431 preserves corneal nerve and epithelial integrity in a murine dry eye model

Yamazaki, R., Yamazoe, K., Yoshida, S., Hatou, S., Inagaki, E., Okano, H., Tsubota, K. & Shimmura, S., 2017 12月 1, In: Scientific reports. 7, 1, 15584.

研究成果: Article › 査読

11 被引用数 (Scopus)

Three-dimensional kinematic and kinetic analysis of quadrupedal walking in the common marmoset (Callithrix jacchus)

Shimada, H., Kanai, R., Kondo, T., Yoshino-Saito, K., Uchida, A., Nakamura, M., Ushiba, J., Okano, H. & Ogihara, N., 2017 12月, In: Neuroscience Research. 125, p. 11-20 10 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Visualization of migration of human cortical neurons generated from induced pluripotent stem cells

Bamba, Y., Kanemura, Y., Okano, H. & Yamasaki, M., 2017 9月 1, In: Journal of Neuroscience Methods. 289, p. 57-63 7 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Whole-Genome DNA Methylation Analyses Revealed Epigenetic Instability in Tumorigenic Human iPS Cell-Derived Neural Stem/Progenitor Cells

Iida, T., Iwanami, A., Sanosaka, T., Kohyama, J., Miyoshi, H., Nagoshi, N., Kashiwagi, R., Toyama, Y., Matsumoto, M., Nakamura, M. & Okano, H., 2017 5月, In: Stem Cells. 35, 5, p. 1316-1327 12 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

2016

A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression

Gallimore, A. R., Aricescu, A. R., Yuzaki, M. & Calinescu, R., 2016, In: PLoS Computational Biology. 12, 1, e1004664.

研究成果: Article › 査読

Open Access

13 被引用数 (Scopus)

Allosteric activation of membrane-bound glutamate receptors using coordination chemistry within living cells

Kiyonaka, S., Kubota, R., Michibata, Y., Sakakura, M., Takahashi, H., Numata, T., Inoue, R., Yuzaki, M. & Hamachi, I., 2016 10月 1, In: Nature Chemistry. 8, 10, p. 958-967 10 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Analysis of induced pluripotent stem cells carrying 22q11.2 deletion

Toyoshima, M., Akamatsu, W., Okada, Y., Ohnishi, T., Balan, S., Hisano, Y., Iwayama, Y., Toyota, T., Matsumoto, T., Itasaka, N., Sugiyama, S., Tanaka, M., Yano, M., Dean, B., Okano, H. & Yoshikawa, T., 2016 11月 1, In: Translational psychiatry. 6, 11, e934.

研究成果: Article › 査読

60 被引用数 (Scopus)

Analysis of RNA metabolism in peripheral WBCs of TDP-43 KI mice identifies novel biomarkers of ALS

Hasegawa, M., Hara-Miyauchi, C., Ohta, H., Sakimura, K., Okano, H. & Okano, H. J., 2016 5月 1, In: Neuroscience Research. 106, p. 12-22 11 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons

Hayashi, Y., Nishimune, H., Hozumi, K., Saga, Y., Harada, A., Yuzaki, M., Iwatsubo, T., Kopan, R. & Tomita, T., 2016 4月 4, In: Scientific reports. 6, 23969.

研究成果: Article › 査読

12 被引用数 (Scopus)

Application of q-space diffusion MRI for the visualization of white matter

Fujiyoshi, K., Hikishima, K., Nakahara, J., Tsuji, O., Hata, J., Konomi, T., Nagai, T., Shibata, S., Kaneko, S., Iwanami, A., Momoshima, S., Takahashi, S., Jinzaki, M., Suzuki, N., Toyama, Y., Nakamura, M. & Okano, H., 2016 3月 2, In: Journal of Neuroscience. 36, 9, p. 2796-2808 13 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research

Morikawa, S., Ouchi, T., Shibata, S., Fujimura, T., Kawana, H., Okano, H. & Nakagawa, T., 2016, In: Stem Cells International. 2016, 2849879.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

CHD7 promotes proliferation of neural stem cells mediated by MIF

Ohta, S., Yaguchi, T., Okuno, H., Chneiweiss, H., Kawakami, Y. & Okano, H., 2016 12月 13, In: Molecular brain. 9, 1, p. 1-12 12 p.

研究成果: Article › 査読

Open Access

20 被引用数 (Scopus)

Combined treatment with chondroitinase ABC and treadmill rehabilitation for chronic severe spinal cord injury in adult rats

Shinozaki, M., Iwanami, A., Fujiyoshi, K., Tashiro, S., Kitamura, K., Shibata, S., Fujita, H., Nakamura, M. & Okano, H., 2016 12月 1, In: Neuroscience Research. 113, p. 37-47 11 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Distinct expression pattern of a deafness gene, KIAA1199, in a primate Cochlea

Hosoya, M., Fujioka, M., Okano, H. & Ogawa, K., 2016, In: BioMed Research International. 2016, 1781894.

研究成果: Article › 査読

12 被引用数 (Scopus)

Distinct Expression Patterns of Causative Genes Responsible for Hereditary Progressive Hearing Loss in Non-Human Primate Cochlea

Hosoya, M., Fujioka, M., Ogawa, K. & Okano, H., 2016 2月 26, In: Scientific reports. 6, 22250.

研究成果: Article › 査読

33 被引用数 (Scopus)

Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins

Fukusumi, H., Shofuda, T., Bamba, Y., Yamamoto, A., Kanematsu, D., Handa, Y., Okita, K., Nakamura, M., Yamanaka, S., Okano, H. & Kanemura, Y., 2016, In: Stem Cells International. 2016, 7235757.

研究成果: Article › 査読

13 被引用数 (Scopus)

Establishment of in Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells

Ichiyanagi, N., Fujimori, K., Yano, M., Ishihara-Fujisaki, C., Sone, T., Akiyama, T., Okada, Y., Akamatsu, W., Matsumoto, T., Ishikawa, M., Nishimoto, Y., Ishihara, Y., Sakuma, T., Yamamoto, T., Tsuiji, H., Suzuki, N., Warita, H., Aoki, M. & Okano, H., 2016 4月 12, In: Stem cell reports. 6, 4, p. 496-510 15 p.

研究成果: Article › 査読

Open Access

48 被引用数 (Scopus)

Expression pattern of wolframin, the WFS1 (Wolfram syndrome-1 gene) product, in common marmoset (Callithrix jacchus) cochlea

Suzuki, N., Hosoya, M., Oishi, N., Okano, H., Fujioka, M. & Ogawa, K., 2016 8月 1, In: NeuroReport. 27, 11, p. 833-836 4 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Fluorescence visualization of the enteric nervous network in a chemically induced aganglionosis model

Fujimura, T., Shibata, S., Shimojima, N., Morikawa, Y., Okano, H. & Kuroda, T., 2016 3月, In: PloS one. 11, 3, e0150579.

研究成果: Article › 査読

4 被引用数 (Scopus)

Functional brain mapping using specific sensory-circuit stimulation and a theoretical graph network analysis in mice with neuropathic allodynia

Komaki, Y., Hikishima, K., Shibata, S., Konomi, T., Seki, F., Yamada, M., Miyasaka, N., Fujiyoshi, K., Okano, H. J., Nakamura, M. & Okano, H., 2016 11月 29, In: Scientific reports. 6, 37802.

研究成果: Article › 査読

Open Access

20 被引用数 (Scopus)

Functional Comparison of Neuronal Cells Differentiated from Human Induced Pluripotent Stem Cell-Derived Neural Stem Cells under Different Oxygen and Medium Conditions

Yamazaki, K., Fukushima, K., Sugawara, M., Tabata, Y., Imaizumi, Y., Ishihara, Y., Ito, M., Tsukahara, K., Kohyama, J. & Okano, H., 2016 12月 1, In: Journal of Biomolecular Screening. 21, 10, p. 1054-1064 11 p.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

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