医化学

研究成果

年別の研究成果 1985 2010 2011 2012 2014 2016 2017 2018 2019 2020 2021 2022

• 439 Article
• 30 Review article
• 8 Chapter
• 8 Conference contribution
• 16 その他
  • 4 Comment/debate
  • 4 Editorial
  • 4 Letter
  • 1 Book
  • 1 Foreword/postscript
  • 1 Paper
  • 1 Short survey

年別の研究成果

年別の研究成果

検索結果

• Article

  Bilirubin Production and Hemeoxygenase-1 Expression in Ischemia-Reperfused Rat Liver in vivo

  Kobayashi, T., Sato, Y., Yamamoto, S., Takeishi, T., Hirano, K. I., Watanabe, T., Kurosaki, I., Shirai, Y., Naito, M., Suematsu, M. & Hatakeyama, K., 2003, In: Japanese Pharmacology and Therapeutics. 31, SUPPL. 1, p. S109-S117+S131

  研究成果: Article › 査読

  • Kupffer Cells 100%
  • Heme Oxygenase-1 97%
  • Bilirubin 81%
  • Ischemia 62%
  • Heme 45%

• Bilirubin rinse: A simple protectant against the rat liver graft injury mimicking heme oxygenase-1 preconditioning

  Kato, Y., Shimazu, M., Kondo, M., Uchida, K., Kumamoto, Y., Wakabayashi, G., Kitajima, M. & Suematsu, M., 2003 8月 1, In: Hepatology. 38, 2, p. 364-373 10 p.

  研究成果: Article › 査読

  • Heme Oxygenase-1 100%
  • Bilirubin 83%
  • Transplants 53%
  • Liver 43%
  • Wounds and Injuries 41%
  93 被引用数 (Scopus)

• Biochemical, metabolomic, and genetic analyses of dephospho coenzyme a kinase involved in coenzyme a biosynthesis in the human enteric parasite entamoeba histolytica

  Nurkanto, A., Jeelani, G., Yamamoto, T., Hishiki, T., Naito, Y., Suematsu, M., Hashimoto, T. & Nozaki, T., 2018 11月 30, In: Frontiers in Microbiology. 9, NOV, 2902.

  研究成果: Article › 査読

  Open Access

  • dephospho-CoA kinase 100%
  • Entamoeba histolytica 59%
  • Coenzymes 58%
  • Metabolomics 50%
  • Parasites 37%
  6 被引用数 (Scopus)

• Biochemical and functional characterization of novel NADH kinase in the enteric protozoan parasite Entamoeba histolytica

  Jeelani, G., Husain, A., Sato, D., Soga, T., Suematsu, M. & Nozaki, T., 2013 2月, In: Biochimie. 95, 2, p. 309-319 11 p.

  研究成果: Article › 査読

  • NAD kinase 100%
  • Enteric Coating 73%
  • Entamoeba histolytica 71%
  • Phosphoryl 60%
  • NAD 55%
  14 被引用数 (Scopus)

• Birth of healthy offspring following ICSI in in vitro-matured common marmoset (Callithrix jacchus) oocytes

  Takahashi, T., Hanazawa, K., Inoue, T., Sato, K., Sedohara, A., Okahara, J., Suemizu, H., Yagihashi, C., Yamamoto, M., Eto, T., Konno, Y., Okano, H., Suematsu, M. & Sasaki, E., 2014 4月 21, In: PloS one. 9, 4, e95560.

  研究成果: Article › 査読

  • Callithrix 100%
  • Callithrix jacchus 99%
  • intracytoplasmic sperm injection 97%
  • Intracytoplasmic Sperm Injections 88%
  • Extrusion 72%
  26 被引用数 (Scopus)

• Brief exposure of skin to near-infrared laser modulates mast cell function and augments the immune response

  Kimizuka, Y., Katagiri, W., Locascio, J. J., Shigeta, A., Sasaki, Y., Shibata, M., Morse, K., Sirbulescu, R. F., Miyatake, M., Reeves, P., Suematsu, M., Gelfand, J., Brauns, T., Poznansky, M. C., Tsukada, K. & Kashiwagi, S., 2018 12月 15, In: Journal of Immunology. 201, 12, p. 3587-3603 17 p.

  研究成果: Article › 査読

  • Mast Cells 100%
  • Lasers 82%
  • Skin 56%
  • Vaccination 23%
  • Vaccines 22%
  10 被引用数 (Scopus)

• Cadmium exposure alters metabolomics of sulfur-containing amino acids in rat testes

  Sugiura, Y., Kashiba, M., Maruyama, K., Hoshikawa, K., Sasaki, R., Saito, K., Kimura, H., Goda, N. & Suematsu, M., 2005 5月, In: Antioxidants and Redox Signaling. 7, 5-6, p. 781-787 7 p.

  研究成果: Article › 査読

  • Cystathionine 100%
  • Sulfur Amino Acids 96%
  • Sulfur-Containing Amino Acid 92%
  • Lyases 73%
  • Cadmium 72%
  31 被引用数 (Scopus)

• Caloric restriction primes mitochondria for ischemic stress by deacetylating specific mitochondrial proteins of the electron transport chain

  Shinmura, K., Tamaki, K., Sano, M., Nakashima-Kamimura, N., Wolf, A. M., Amo, T., Ohta, S., Katsumata, Y., Fukuda, K., Ishiwata, K., Suematsu, M. & Adachi, T., 2011 8月 5, In: Circulation research. 109, 4, p. 396-406 11 p.

  研究成果: Article › 査読

  • Caloric Restriction 100%
  • Mitochondrial Proteins 90%
  • Protein Transport 87%
  • Electron Transport 87%
  • Mitochondria 65%
  72 被引用数 (Scopus)

• Cancer-derived cholesterol sulfate is a key mediator to prevent tumor infiltration by effector T cells

  Tatsuguchi, T., Uruno, T., Sugiura, Y., Sakata, D., Izumi, Y., Sakurai, T., Hattori, Y., Oki, E., Kubota, N., Nishimoto, K., Oyama, M., Kunimura, K., Ohki, T., Bamba, T., Tahara, H., Sakamoto, M., Nakamura, M., Suematsu, M. & Fukui, Y., 2022 4月 20, In: International immunology. 34, 5, p. 277-289 13 p.

  研究成果: Article › 査読

  Open Access

  • cholesteryl sulfate 100%
  • T-Lymphocytes 36%
  • Oxysterols 21%
  • Neoplasms 19%
  • Tumor Escape 13%
  1 被引用数 (Scopus)

• Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells

  Tsugawa, H., Kato, C., Mori, H., Matsuzaki, J., Kameyama, K., Saya, H., Hatakeyama, M., Suematsu, M. & Suzuki, H., 2019, In: CMGH. 8, 3, p. 319-334 16 p.

  研究成果: Article › 査読

  Open Access

  • Helicobacter 100%
  • Neoplastic Stem Cells 76%
  • Catenins 38%
  • Protein Splicing 30%
  • Histones 28%
  13 被引用数 (Scopus)

• Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle

  Iso, T., Maeda, K., Hanaoka, H., Suga, T., Goto, K., Syamsunarno, M. R. A. A., Hishiki, T., Nagahata, Y., Matsui, H., Arai, M., Yamaguchi, A., Abumrad, N. A., Sano, M., Suematsu, M., Endo, K., Hotamisligil, G. S. & Kurabayashi, M., 2013 11月, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 11, p. 2549-2557 9 p.

  研究成果: Article › 査読

  • Fatty Acid-Binding Proteins 100%
  • Capillaries 74%
  • Fatty Acids 65%
  • Myocardium 63%
  • Skeletal Muscle 60%
  75 被引用数 (Scopus)

• Capsaicin binds to prohibitin 2 and displaces it from the mitochondria to the nucleus

  Kuramori, C., Azuma, M., Kume, K., Kaneko, Y., Inoue, A., Yamaguchi, Y., Kabe, Y., Hosoya, T., Kizaki, M., Suematsu, M. & Handa, H., 2009 2月 6, In: Biochemical and Biophysical Research Communications. 379, 2, p. 519-525 7 p.

  研究成果: Article › 査読

  • prohibitin 100%
  • Capsaicin 90%
  • Mitochondria 52%
  • Apoptosis 22%
  • Antalgic Agent 14%
  43 被引用数 (Scopus)

• CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy

  Tsugawa, H., Mori, H., Matsuzaki, J., Sato, A., Saito, Y., Imoto, M., Suematsu, M. & Suzuki, H., 2019 2月 1, In: Autophagy. 15, 2, p. 242-258 17 p.

  研究成果: Article › 査読

  • Actin Capping Proteins 100%
  • Lysosomal-Associated Membrane Protein 1 89%
  • Low Density Lipoprotein Receptor-Related Protein-1 86%
  • Helicobacter pylori 57%
  • Autophagy 56%
  17 被引用数 (Scopus)

• Carbon monoxide: An endogenous modulator of sinusoidal tone in the perfused rat liver

  Suematsu, M., Goda, N., Sano, T., Kashiwagi, S., Egawa, T., Shinoda, Y. & Ishimura, Y., 1995 11月, In: Journal of Clinical Investigation. 96, 5, p. 2431-2437 7 p.

  研究成果: Article › 査読

  Open Access

  • Carbon Monoxide 100%
  • Hepatic Stellate Cells 60%
  • Liver 50%
  • Constriction 47%
  • Heme Oxygenase (Decyclizing) 44%
  356 被引用数 (Scopus)

• Carbon monoxide as a guardian against hepatobiliary dysfunction

  Suematsu, M., Tsukada, K., Tajima, T., Yamamoto, T., Ochiai, D., Watanabe, H., Yoshimura, Y. & Goda, N., 2005 11月, In: Alcoholism: Clinical and Experimental Research. 29, 11 SUPPL., p. 134S-139S

  研究成果: Article › 査読

  • Carbon Monoxide 100%
  • Heme 64%
  • Heme Oxygenase (Decyclizing) 37%
  • Soluble Guanylyl Cyclase 36%
  • Heme Oxygenase-1 32%
  6 被引用数 (Scopus)

• Carbon monoxide as an endogenous modulator of hepatic vascular perfusion

  Suematsu, M., Kashiwagi, S., Sano, T., Goda, N., Shinoda, Y. & Ishimura, Y., 1994 12月 15, In: Biochemical and Biophysical Research Communications. 205, 2, p. 1333-1337 5 p.

  研究成果: Article › 査読

  • Carbon Monoxide 100%
  • Heme Oxygenase (Decyclizing) 79%
  • Perfusion 74%
  • Blood Vessels 57%
  • Liver 50%
  139 被引用数 (Scopus)

• Carbon monoxide as a regulator of bile canalicular contractility in cultured rat hepatocytes

  Shinoda, Y., Suematsu, M., Wakabayashi, Y., Suzuki, T., Goda, N., Saito, S., Yamaguchi, T. & Ishimura, Y., 1998, In: Hepatology. 28, 2, p. 286-295 10 p.

  研究成果: Article › 査読

  • zinc protoporphyrin 100%
  • Carbon Monoxide 68%
  • Bile 66%
  • Hepatocytes 56%
  • Heme Oxygenase (Decyclizing) 45%
  58 被引用数 (Scopus)

• Carbon monoxide from heme catabolism protects against hepatobiliary dysfunction in endotoxin-treated rat liver

  Kyokane, T., Norimizu, S., Taniai, H., Yamaguchi, T., Takeoka, S., Tsuchida, E., Naito, M., Nimura, Y., Ishimura, Y. & Suematsu, M., 2001 1月 1, In: Gastroenterology. 120, 5, p. 1227-1240 14 p.

  研究成果: Article › 査読

  • Heme 100%
  • Carbon Monoxide 91%
  • Endotoxins 90%
  • Liver 46%
  • Heme Oxygenase (Decyclizing) 45%
  147 被引用数 (Scopus)

• Carbon monoxide from heme oxygenase-2 is a tonic regulator against NO-dependent vasodilatation in the adult rat cerebral microcirculation

  Ishikawa, M., Kajimura, M., Adachi, T., Maruyama, K., Makino, N., Goda, N., Yamaguchi, T., Sekizuka, E. & Suematsu, M., 2005 12月, In: Circulation research. 97, 12, p. e104-e114

  研究成果: Article › 査読

  • heme oxygenase-2 100%
  • Microcirculation 65%
  • Carbon Monoxide 63%
  • Vasodilation 60%
  • Heme Oxygenase (Decyclizing) 31%
  74 被引用数 (Scopus)

• Carbon monoxide-mediated alterations in paracellular permeability and vesicular transport in acetaminophen-treated perfused rat liver

  Mori, M., Suematsu, M., Kyokane, T., Sano, T., Suzuki, H., Yamaguchi, T., Ishimura, Y. & Ishii, H., 1999, In: Hepatology. 30, 1, p. 160-168 9 p.

  研究成果: Article › 査読

  • Acetaminophen 100%
  • Carbon Monoxide 96%
  • Heme Oxygenase (Decyclizing) 85%
  • Permeability 81%
  • Heme 52%
  31 被引用数 (Scopus)

• Carbon monoxide modulates endotoxin-induced microvascular leukocyte adhesion through platelet-dependent mechanisms

  Morisaki, H., Katayama, T., Kotake, Y., Ito, M., Handa, M., Ikeda, Y., Takeda, J. & Suematsu, M., 2002 9月 1, In: Anesthesiology. 97, 3, p. 701-709 9 p.

  研究成果: Article › 査読

  • Carbon Monoxide 100%
  • Endotoxins 97%
  • Heme Oxygenase-1 82%
  • Leukocytes 77%
  • Blood Platelets 76%
  38 被引用数 (Scopus)

• Carbon monoxide overproduced by heme oxygenase-1 causes a reduction of vascular resistance in perfused rat liver

  Wakabayashi, Y., Takamiya, R., Mizuki, A., Kyokane, T., Goda, N., Yamaguchi, T., Takeoka, S., Tsuchida, E., Suematsu, M. & Ishimura, Y., 1999 11月, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 277, 5 40-5, p. G1088-G1096

  研究成果: Article › 査読

  • Heme Oxygenase-1 100%
  • Carbon Monoxide 86%
  • Vascular Resistance 80%
  • Liver 43%
  • Hemin 42%
  62 被引用数 (Scopus)

• Carbon monoxide stimulates global protein methylation via its inhibitory action on cystathionine β-synthase

  Yamamoto, T., Takano, N., Ishiwata, K. & Suematsu, M., 2011 1月, In: Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 96-100 5 p.

  研究成果: Article › 査読

  • Cystathionine 100%
  • Carbon Monoxide 65%
  • Methylation 58%
  • Arginine 38%
  • Hydrogen Sulfide 26%
  28 被引用数 (Scopus)

• Carbon monoxide stimulates mrp2-dependent excretion of bilirubin-IXα into bile in the perfused rat liver

  Norimizu, S., Kudo, A., Kajimura, M., Ishikawa, K., Taniai, H., Yamaguchi, T., Fujii, K., Arii, S., Nimura, Y. & Suematsu, M., 2003 8月, In: Antioxidants and Redox Signaling. 5, 4, p. 449-456 8 p.

  研究成果: Article › 査読

  • Carbon Monoxide 100%
  • Bile 97%
  • Bilirubin 96%
  • Liver 50%
  • Hepatobiliary Elimination 33%
  19 被引用数 (Scopus)

• Case report: Nodule development from subcapsular aldosterone-producing cell clusters causes hyperaldosteronism

  Nishimoto, K., Seki, T., Kurihara, I., Yokota, K., Omura, M., Nishikawa, T., Shibata, H., Kosaka, T., Oya, M., Suematsu, M. & Mukai, K., 2016 1月, In: Journal of Clinical Endocrinology and Metabolism. 101, 1, p. 6-9 4 p.

  研究成果: Article › 査読

  Open Access

  • Hyperaldosteronism 100%
  • Aldosterone 81%
  • Mutation 66%
  • Adenoma 51%
  • Molecular Cluster 51%
  59 被引用数 (Scopus)

• Cell-free synthesis of cytochrome c oxidase, a multicomponent membrane protein

  Katayama, Y., Shimokata, K., Suematsu, M., Ogura, T., Tsukihara, T., Yoshikawa, S. & Shimada, H., 2010 6月, In: Journal of Bioenergetics and Biomembranes. 42, 3, p. 235-240 6 p.

  研究成果: Article › 査読

  • Electron Transport Complex IV 100%
  • Membrane Proteins 70%
  • Paracoccus denitrificans 36%
  • Proteins 31%
  • Amino Acids 29%
  9 被引用数 (Scopus)

• Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target

  Nurkanto, A., Jeelani, G., Yamamoto, T., Naito, Y., Hishiki, T., Mori, M., Suematsu, M., Shiomi, K., Hashimoto, T. & Nozaki, T., 2018 4月, In: International Journal for Parasitology: Drugs and Drug Resistance. 8, 1, p. 125-136 12 p.

  研究成果: Article › 査読

  Open Access

  • pantothenate kinase 100%
  • Entamoeba histolytica 74%
  • coenzyme A 68%
  • Coenzyme A 56%
  • phosphotransferases (kinases) 48%
  7 被引用数 (Scopus)

• Characterization of skin microbiota in patients with atopic dermatitis and in normal subjects using 16S rRNA gene-based comprehensive analysis

  Dekio, I., Sakamoto, M., Hayashi, H., Amagai, M., Suematsu, M. & Benno, Y., 2007 12月, In: Journal of Medical Microbiology. 56, 12, p. 1675-1683 9 p.

  研究成果: Article › 査読

  • Atopic Dermatitis 100%
  • rRNA Genes 99%
  • 16S Ribosomal RNA 99%
  • Microbiota 94%
  • Skin 52%
  60 被引用数 (Scopus)

• Cholesterol 25-hydroxylase is a metabolic switch to constrain T cell–mediated inflammation in the skin

  Takahashi, H., Nomura, H., Iriki, H., Kubo, A., Isami, K., Mikami, Y., Mukai, M., Sasaki, T., Yamagami, J., Kudoh, J., Ito, H., Kamata, A., Kurebayashi, Y., Yoshida, H., Yoshimura, A., Sun, H. W., Suematsu, M., O’Shea, J. J., Kanno, Y. & Amagai, M., 2021, In: Science Immunology. 6, 64, eabb6444.

  研究成果: Article › 査読

  • cholesterol 25-hydroxylase 100%
  • Interleukin-27 43%
  • T-Lymphocytes 31%
  • Inflammation 30%
  • Skin 28%

• Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

  Sakurai, T., Uruno, T., Sugiura, Y., Tatsuguchi, T., Yamamura, K., Ushijima, M., Hattori, Y., Kukimoto-Niino, M., Mishima-Tsumagari, C., Watanabe, M., Suematsu, M. & Fuku, Y., 2018 7月 31, In: Science Signaling. 11, 541, eaao4874.

  研究成果: Article › 査読

  • Cholesterol Sulfate 100%
  • cholesteryl sulfate 98%
  • Immune Evasion 74%
  • Cytokinesis 70%
  • Eye 36%
  18 被引用数 (Scopus)

• Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1

  Johnston, B., Burns, A. R., Suematsu, M., Issekutz, T. B., Woodman, R. C. & Kubes, P., 1999 5月, In: Journal of Clinical Investigation. 103, 9, p. 1269-1276 8 p.

  研究成果: Article › 査読

  Open Access

  • Chemokine Receptors 100%
  • Chemokine CCL2 99%
  • Leukocytes 70%
  • Neutrophils 69%
  • Up-Regulation 64%
  164 被引用数 (Scopus)

• Cilostazol strengthens the endothelial barrier of postcapillary venules from the rat mesentery in situ

  Sugiura, Y., Morikawa, T., Takenouchi, T., Suematsu, M. & Kajimura, M., 2014 10月, In: Phlebology. 29, 9, p. 594-599 6 p.

  研究成果: Article › 査読

  • Cilostazol 100%
  • Mesentery 83%
  • Venules 81%
  • Histamine 26%
  • Phosphodiesterase 3 Inhibitors 21%
  4 被引用数 (Scopus)

• Clinical relevance of oxidative stress--with special references to organ microcirculatory disturbance

  Suematsu, M. & Tsuchiya, M., 1990 9月 10, In: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine. 79, 9, p. 1208-1213 6 p.

  研究成果: Article › 査読

  Open Access

• Clinical Relevance of Oxidative Stress with Special Reference to Organ Microcirculatory Disturbances

  Suematsu, M. & Tsuchiya, M., 1990, In: Japanese Journal of Medicine. 29, 6, p. 674-677 4 p.

  研究成果: Article › 査読

  Open Access

• Comparison of a Novel Bisphosphonate Prodrug and Zoledronic Acid in the Induction of Cytotoxicity in Human Vγ2Vδ2 T Cells

  Okuno, D., Sugiura, Y., Sakamoto, N., Tagod, M. S. O., Iwasaki, M., Noda, S., Tamura, A., Senju, H., Umeyama, Y., Yamaguchi, H., Suematsu, M., Morita, C. T., Tanaka, Y. & Mukae, H., 2020 7月 21, In: Frontiers in Immunology. 11, 1405.

  研究成果: Article › 査読

  Open Access

  • Zoledronic Acid 100%
  • Prodrugs 84%
  • Diphosphonates 83%
  • T-Lymphocytes 47%
  • 3,3-dimethylallyl pyrophosphate 23%
  2 被引用数 (Scopus)

• Conditionally immortalized adrenocortical cell lines at undifferentiated states exhibit inducible expression of glucocorticoid-synthesizing genes

  Mukai, K., Nagasawa, H., Agake-Suzuki, R., Mitani, F., Totani, K., Yanai, N., Obinata, M., Suematsu, M. & Ishimura, Y., 2002, In: European Journal of Biochemistry. 269, 1, p. 69-81 13 p.

  研究成果: Article › 査読

  • Aldosterone 100%
  • Corticosterone 99%
  • Steroid 65%
  • Glucocorticoids 64%
  • Cell Line 41%
  15 被引用数 (Scopus)

• Constitutive expression of ICAM-1 in rat microvascular systems analyzed by laser confocal microscopy

  Iigo, Y., Suematsu, M., Higashida, T., Oheda, J. I., Matsumoto, K., Wakabayashi, Y., Ishimura, Y., Miyasaka, M. & Takashi, T., 1997, In: American Journal of Physiology - Heart and Circulatory Physiology. 42, 1

  研究成果: Article › 査読

  • rat ICAM1 protein 100%
  • Venules 64%
  • Confocal Microscopy 51%
  • Mesentery 49%
  • Intercellular Adhesion Molecule-1 42%

• Constitutive expression of ICAM-1 in rat microvascular systems analyzed by laser confocal microscopy

  Iigo, Y., Suematsu, M., Higashida, T., Oheda, J. I., Matsumoto, K., Wakabayashi, Y., Ishimura, Y., Miyasaka, M. & Takashi, T., 1997 7月, In: American Journal of Physiology - Heart and Circulatory Physiology. 273, 1 42-1, p. H138-H147

  研究成果: Article › 査読

  • rat ICAM1 protein 100%
  • Venules 64%
  • Intercellular Adhesion Molecule-1 56%
  • Confocal Microscopy 51%
  • Mesentery 49%
  68 被引用数 (Scopus)

• Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis

  Bai, Z., Cai, L., Umemoto, E., Takeda, A., Tohya, K., Komai, Y., Veeraveedu, P. T., Hata, E., Sugiura, Y., Kubo, A., Suematsu, M., Hayasaka, H., Okudaira, S., Aoki, J., Tanaka, T., Albers, H. M. H. G., Ovaa, H. & Miyasaka, M., 2013 3月 1, In: Journal of Immunology. 190, 5, p. 2036-2048 13 p.

  研究成果: Article › 査読

  • lysophosphatidic acid 100%
  • Venules 88%
  • Basement Membrane 73%
  • Lymphocytes 51%
  • Endothelial Cells 25%
  81 被引用数 (Scopus)

• Contribution of efflux pumps to clarithromycin resistance in Helicobacter pylori

  Hirata, K., Suzuki, H., Nishizawa, T., Tsugawa, H., Muraoka, H., Saito, Y., Matsuzaki, J. & Hibi, T., 2010 5月, In: Journal of Gastroenterology and Hepatology (Australia). 25, SUPPL. 1, p. S75-S79

  研究成果: Article › 査読

  • Clarithromycin 100%
  • Helicobacter pylori 81%
  • 23S Ribosomal RNA 38%
  • Point Mutation 27%
  • phenylalanylarginine-naphthylamide 18%
  79 被引用数 (Scopus)

• CO overproduction is responcible for heme oxygenase 1-mediated microvascular hyporeactivity in perfused rat liver

  Wakabayashi, Y., Takamiya, R., Mizuki, A., Suematsu, M. & Ishimura, Y., 1998 3月 20, In: FASEB Journal. 12, 5, p. A1001

  研究成果: Article › 査読

  • Heme Oxygenase-1 100%
  • Carbon Monoxide 86%
  • Heme 78%
  • Liver 43%
  • Vascular Resistance 40%

• Cortical microcirculatory disturbance in the super acute phase of subarachnoid hemorrhage - In vivo analysis using two-photon laser scanning microscopy

  Ishikawa, M., Kajimura, M., Morikawa, T., Tsukada, K., Tsuji, T., Kusaka, G., Tanaka, Y. & Suematsu, M., 2016 9月 15, In: Journal of the Neurological Sciences. 368, p. 326-333 8 p.

  研究成果: Article › 査読

  • Photons 100%
  • Subarachnoid Hemorrhage 99%
  • Confocal Microscopy 89%
  • Arterioles 68%
  • Erythrocytes 24%
  10 被引用数 (Scopus)

• Coupling of angiogenesis and odontogenesis orchestrates tooth mineralization in mice

  Matsubara, T., Iga, T., Sugiura, Y., Kusumoto, D., Sanosaka, T., Tai-Nagara, I., Takeda, N., Fong, G. H., Ito, K., Ema, M., Okano, H., Kohyama, J., Suematsu, M. & Kubota, Y., 2022 4月 4, In: Journal of Experimental Medicine. 219, 4, e20211789.

  研究成果: Article › 査読

  • Odontogenesis 100%
  • Dentinogenesis 51%
  • Capillaries 46%
  • Tooth 45%
  • Odontoblasts 43%

• Critical role for CXC chemokine ligand 16 (SR-PSOX) in Th1 response mediated by NKT cells

  Shimaoka, T., Seino, K. I., Kume, N., Minami, M., Nishime, C., Suematsu, M., Kita, T., Taniguchi, M., Matsushima, K. & Yonehara, S., 2007 12月 15, In: Journal of Immunology. 179, 12, p. 8172-8179 8 p.

  研究成果: Article › 査読

  Open Access

  • Chemokine CXCL16 100%
  • Natural Killer T-Cells 66%
  • Galactosylceramides 49%
  • Interleukin-4 22%
  • CXCR6 Receptors 14%
  47 被引用数 (Scopus)

• Crosstalk between glucocorticoid receptor and nutritional sensor mTOR in skeletal muscle

  Shimizu, N., Yoshikawa, N., Ito, N., Maruyama, T., Suzuki, Y., Takeda, S. I., Nakae, J., Tagata, Y., Nishitani, S., Takehana, K., Sano, M., Fukuda, K., Suematsu, M., Morimoto, C. & Tanaka, H., 2011 2月 2, In: Cell Metabolism. 13, 2, p. 170-182 13 p.

  研究成果: Article › 査読

  • Glucocorticoid Receptors 100%
  • Skeletal Muscle 71%
  • Muscles 27%
  • Muscular Atrophy 25%
  • Ubiquitin-Protein Ligases 25%
  327 被引用数 (Scopus)

• C-type lectin Mincle mediates cell death-triggered inflammation in acute kidney injury

  Tanaka, M., Saka-Tanaka, M., Ochi, K., Fujieda, K., Sugiura, Y., Miyamoto, T., Kohda, H., Ito, A., Miyazawa, T., Matsumoto, A., Aoe, S., Miyamoto, Y., Tsuboi, N., Maruyama, S., Suematsu, M., Yamasaki, S., Ogawa, Y. & Suganami, T., 2020 8月, In: Journal of Experimental Medicine. 217, 11, e20192230.

  研究成果: Article › 査読

  Open Access

  • C-Type Lectins 100%
  • Acute Kidney Injury 70%
  • Cell Death 56%
  • Glucosylceramides 53%
  • Macrophages 51%
  16 被引用数 (Scopus)

• Cystathionine β-synthase as a carbon monoxide-sensitive regulator of bile excretion

  Shintani, T., Iwabuchi, T., Soga, T., Kato, Y., Yamamoto, T., Takano, N., Hishiki, T., Ueno, Y., Ikeda, S., Sakuragawa, T., Ishikawa, K., Goda, N., Kitagawa, Y., Kajimura, M., Matsumoto, K. & Suematsu, M., 2009, In: Hepatology. 49, 1, p. 141-150 10 p.

  研究成果: Article › 査読

  • Cystathionine 100%
  • Carbon Monoxide 65%
  • Bile 63%
  • Heme Oxygenase (Decyclizing) 21%
  • Metabolome 18%
  89 被引用数 (Scopus)

• Cystathionine γ-lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury

  Ishii, I., Akahoshi, N., Yamada, H., Nakano, S., Izumi, T. & Suematsu, M., 2010 8月 20, In: Journal of Biological Chemistry. 285, 34, p. 26358-26368 11 p.

  研究成果: Article › 査読

  • Cystathionine 100%
  • Lyases 92%
  • Lethal 76%
  • Muscular Diseases 69%
  • Cysteine 60%
  169 被引用数 (Scopus)

• Cytochrome P-450_17α in β-cells of rat pancreas and its local steroidogenesis

  Ogishima, T., Mitani, F. & Suematsu, M., 2008 7月, In: Journal of Steroid Biochemistry and Molecular Biology. 111, 1-2, p. 80-86 7 p.

  研究成果: Article › 査読

  • Cytochromes 100%
  • Lyases 94%
  • Oxidoreductases 80%
  • Androstenedione 79%
  • Cytochrome 75%
  13 被引用数 (Scopus)

• Cytologic features of oral squamous cell carcinoma in an Indo-Pacific bottlenose dolphin (Tursiops aduncus): Papanicolaou stain and immunocytochemistry using liquid-based cytology

  Ohsaki, H., Ueda, K., Minakawa, T., Oshiro, M., Kamoshida, S., Sugiura, Y., Suzuki, M. & Nishiyama, A., 2021 9月, In: Veterinary Clinical Pathology. 50, 3, p. 404-409 6 p.

  研究成果: Article › 査読

  • Tursiops aduncus 100%
  • Bottle-Nosed Dolphin 98%
  • squamous cell carcinoma 85%
  • immunocytochemistry 67%
  • cell biology 64%