医化学

Article

Cytotoxic effect of amide derivatives of trifluoromethionine against the enteric protozoan parasite Entamoeba histolytica

Sato, D., Kobayashi, S., Yasui, H., Shibata, N., Toru, T., Yamamoto, M., Tokoro, G., Ali, V., Soga, T., Takeuchi, T., Suematsu, M. & Nozaki, T., 2010 1月, In: International journal of antimicrobial agents. 35, 1, p. 56-61 6 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Daily regeneration of rat adrenocortical cells: Circadian and zonal variations in cytogenesis

Miyamoto, H., Mitani, F., Mukai, K., Suematsu, M. & Ishimura, Y., 2000, In: Endocrine Research. 26, 4, p. 899-904 6 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Decreased expression of cystathionine β-synthase promotes glioma tumorigenesis

Takano, N., Sarfraz, Y., Gilkes, D. M., Chaturvedi, P., Xiang, L., Suematsu, M., Zagzag, D. & Semenza, G. L., 2014 10月 1, In: Molecular Cancer Research. 12, 10, p. 1398-1406 9 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

Decreased Mrp2-Dependent Bile Flow in the Post-Warm Ischemic Rat Liver

Ban, D., Kudo, A., Sui, S., Tanaka, S., Nakamura, N., Ito, K., Suematsu, M. & Arii, S., 2009 5月 15, In: Journal of Surgical Research. 153, 2, p. 310-316 7 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Deep whole-genome sequencing reveals recent selection signatures linked to evolution and disease risk of Japanese

Okada, Y., Momozawa, Y., Sakaue, S., Kanai, M., Ishigaki, K., Akiyama, M., Kishikawa, T., Arai, Y., Sasaki, T., Kosaki, K., Suematsu, M., Matsuda, K., Yamamoto, K., Kubo, M., Hirose, N. & Kamatani, Y., 2018 12月 1, In: Nature communications. 9, 1, 1631.

研究成果: Article › 査読

Open Access

72 被引用数 (Scopus)

Delayed gastric emptying and disruption of the interstitial cells of Cajal network after gastric ischaemia and reperfusion

Suzuki, S., Suzuki, H., Horiguchi, K., Tsugawa, H., Matsuzaki, J., Takagi, T., Shimojima, N. & Hibi, T., 2010 5月, In: Neurogastroenterology and Motility. 22, 5, p. 585-593+e126

研究成果: Article › 査読

27 被引用数 (Scopus)

Dendropanax morbiferus leaf extract facilitates oligodendrocyte development

Kim, J. Y., Yoon, J. Y., Sugiura, Y., Lee, S. K., Park, J. D., Song, G. J. & Yang, H. J., 2019 6月 1, In: Royal Society Open Science. 6, 6, 190266.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging

Sugiyama, E., Guerrini, M. M., Honda, K., Hattori, Y., Abe, M., Källback, P., Andrén, P. E., Tanaka, K. F., Setou, M., Fagarasan, S., Suematsu, M. & Sugiura, Y., 2019 10月 25, In: iScience. 20, p. 359-372 14 p.

研究成果: Article › 査読

Open Access

16 被引用数 (Scopus)

Detection of potentially novel bacterial components of the human skin microbiota using culture-independent molecular profiling

Dekio, I., Hayashi, H., Sakamoto, M., Kitahara, M., Nishikawa, T., Suematsu, M. & Benno, Y., 2005 12月, In: Journal of Medical Microbiology. 54, 12, p. 1231-1238 8 p.

研究成果: Article › 査読

97 被引用数 (Scopus)

Development and application of high-performance affinity beads: Toward chemical biology and drug discovery

Sakamoto, S., Kabe, Y., Hatakeyama, M., Yamaguchi, Y. & Handa, H., 2009, In: Chemical Record. 9, 1, p. 66-85 20 p.

研究成果: Article › 査読

60 被引用数 (Scopus)

Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera

Kabe, Y., Suematsu, M., Sakamoto, S., Hirai, M., Koike, I., Hishiki, T., Matsuda, A., Hasegawa, Y., Tsujita, K., Ono, M., Minegishi, N., Hozawa, A., Murakami, Y., Kubo, M., Itonaga, M. & Handa, H., 2018 10月, In: Clinical Chemistry. 64, 10, p. 1463-1473 11 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

Development of a novel microRNA promoter microarray for ChIP-on-chip assay to identify epigenetically regulated microRNAs

Saito, Y., Suzuki, H., Taya, T., Nishizawa, M., Tsugawa, H., Matsuzaki, J., Hirata, K., Saito, H. & Hibi, T., 2012 9月 14, In: Biochemical and Biophysical Research Communications. 426, 1, p. 33-37 5 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Development of functional zonation in the rat adrenal cortex

Mitani, F., Mukai, K., Miyamoto, H., Suematsu, M. & Ishimura, Y., 1999, In: Endocrinology. 140, 7, p. 3342-3353 12 p.

研究成果: Article › 査読

Open Access

78 被引用数 (Scopus)

Development of imaging mass spectrometry (IMS) dataset extractor software, IMS convolution

Hayasaka, T., Goto-Inoue, N., Ushijima, M., Yao, I., Yuba-Kubo, A., Wakui, M., Kajihara, S., Matsuura, M. & Setou, M., 2011 7月, In: Analytical and bioanalytical chemistry. 401, 1, p. 183-193 11 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption

Soga, T., Baran, R., Suematsu, M., Ueno, Y., Ikeda, S., Sakurakawa, T., Kakazu, Y., Ishikawa, T., Robert, M., Nishioka, T. & Tomita, M., 2006 6月 16, In: Journal of Biological Chemistry. 281, 24, p. 16768-16776 9 p.

研究成果: Article › 査読

529 被引用数 (Scopus)

Direct profiling of the phospholipid composition of adult Caenorhabditis elegans using whole-body imaging mass spectrometry

Hameed, S., Ikegami, K., Sugiyama, E., Matsushita, S., Kimura, Y., Hayasaka, T., Sugiura, Y., Masaki, N., Waki, M., Ohta, I., Hossen, M. A. & Setou, M., 2017 10月, In: Analytical and bioanalytical chemistry. 407, 25, p. 7589-7602 14 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Discontinuous total parenteral nutrition prevents postischemic mitochondrial dysfunction in rat liver

Morikawa, N., Suematsu, M., Kyokane, T., Goda, N., Kumamoto, Y., Okitsu, T., Ishimura, Y. & Kitajima, M., 1998 11月 10, In: Hepatology. 28, 5, p. 1289-1299 11 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Discovery of Pancreatic Ductal Adenocarcinoma-Related Aberrant Glycosylations: A Multilateral Approach of Lectin Microarray-Based Tissue Glycomic Profiling With Public Transcriptomic Datasets

Wagatsuma, T., Nagai-Okatani, C., Matsuda, A., Masugi, Y., Imaoka, M., Yamazaki, K., Sakamoto, M. & Kuno, A., 2020 3月 13, In: Frontiers in Oncology. 10, 338.

研究成果: Article › 査読

Open Access

10 被引用数 (Scopus)

Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study

Uchida, T., Nishimoto, K., Fukumura, Y., Asahina, M., Goto, H., Kawano, Y., Shimizu, F., Tsujimura, A., Seki, T., Mukai, K., Kabe, Y., Suematsu, M., Gomez-Sanchez, C. E., Yao, T., Horie, S. & Watada, H., 2017 3月 1, In: Endocrine pathology. 28, 1, p. 27-35 9 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Disruption of HIF-1α in hepatocytes impairs glucose metabolism in diet-induced obesity mice

Ochiai, D., Goda, N., Hishiki, T., Kanai, M., Senoo-Matsuda, N., Soga, T., Johnson, R. S., Yoshimura, Y. & Suematsu, M., 2011 11月 25, In: Biochemical and Biophysical Research Communications. 415, 3, p. 445-449 5 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation

Goda, N., Suzuki, K., Naito, M., Takeoka, S., Tsuchida, E., Ishimura, Y., Tamatani, T. & Suematsu, M., 1998 2月 1, In: Journal of Clinical Investigation. 101, 3, p. 604-612 9 p.

研究成果: Article › 査読

Open Access

245 被引用数 (Scopus)

Distribution of heme oxygenase isoforms in rat liver characterized by novel monoclonal antibodies

Goda, N., Naito, M., Tamatani, T., Ishimura, Y. & Suematsu, M., 1998 3月 20, In: FASEB Journal. 12, 5, p. A1001

研究成果: Article › 査読

Distribution of inhaled volatile β-caryophyllene and dynamic changes of liver metabolites in mice

Takemoto, Y., Kishi, C., Sugiura, Y., Yoshioka, Y., Matsumura, S., Moriyama, T. & Zaima, N., 2021 12月, In: Scientific reports. 11, 1, 1728.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Distribution of tubulointerstitial nephritis antigen-like 1 and structural matrix proteins in mouse embryos during preimplantation development in vivo and in vitro

Sakurai, M., Sato, Y., Mukai, K., Suematsu, M., Fukui, E., Yoshizawa, M., Tanemura, K., Hoshino, Y., Matsumoto, H. & Sato, E., 2014 5月, In: Zygote. 22, 2, p. 259-265 7 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine-producing metabolic pathway

Nishikawa, K., Iwamoto, Y., Kobayashi, Y., Katsuoka, F., Kawaguchi, S. I., Tsujita, T., Nakamura, T., Kato, S., Yamamoto, M., Takayanagi, H. & Ishii, M., 2015, In: Nature Medicine. 21, 3, p. 281-287 7 p.

研究成果: Article › 査読

142 被引用数 (Scopus)

DNA repair factor KAT5 prevents ischemic acute kidney injury through glomerular filtration regulation

Hishikawa, A., Hayashi, K., Kubo, A., Miyashita, K., Hashiguchi, A., Kinouchi, K., Yoshimoto, N., Nakamichi, R., Akashio, R., Sugita, E., Azegami, T., Monkawa, T., Suematsu, M. & Itoh, H., 2021 12月 17, In: iScience. 24, 12, 103436.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Dynamic Simulation and Metabolome Analysis of Long-Term Erythrocyte Storage in Adenine-Guanosine Solution

Nishino, T., Yachie-Kinoshita, A., Hirayama, A., Soga, T., Suematsu, M. & Tomita, M., 2013 8月 16, In: PloS one. 8, 8, e71060.

研究成果: Article › 査読

29 被引用数 (Scopus)

Dysfunctional gastric emptying with down-regulation of muscle-specific MicroRNAs in helicobacter pylori-infected mice

Saito, Y., Suzuki, H., Tsugawa, H., Suzuki, S., Matsuzaki, J., Hirata, K. & Hibi, T., 2011 1月, In: Gastroenterology. 140, 1, p. 189-198 10 p.

研究成果: Article › 査読

53 被引用数 (Scopus)

Early midzonal oxidative stress preceding cell death in hypoperfused rat liver

Suematsu, M., Suzuki, H., Ishii, H., Kato, S., Yanagisawa, T., Asako, H., Suzuki, M. & Tsuchiya, M., 1992 9月, In: Gastroenterology. 103, 3, p. 994-1001 8 p.

研究成果: Article › 査読

81 被引用数 (Scopus)

Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1

Negishi, N., Suzuki, D., Ito, R., Irie, N., Matsuo, K., Yahata, T., Nagano, K., Aoki, K., Ohya, K., Hozumi, K., Ando, K., Tamaoki, N., Ito, M. & Habu, S., 2014 6月, In: Experimental Hematology. 42, 6, p. 487-494.e1

研究成果: Article › 査読

6 被引用数 (Scopus)

Effect of lipopolysaccharides on erythrocyte flow velocity in rat liver

Horie, Y., Kato, S., Ohki, E., Hamamatsu, H., Fukumura, D., Kurose, I., Suzuki, H., Suematsu, M., Miura, S. & Ishii, H., 1997 12月, In: Journal of gastroenterology. 32, 6, p. 783-790 8 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Effect of rat CINC/gro, a member of the interleukin-8 family, on leukocytes in microcirculation of the rat mesentery

Watanabe, K., Suematsu, M., Iida, M., Takaishi, K., Iizuka, Y., Suzuki, H., Suzuki, M., Tsuchiya, M. & Tsurufuji, S., 1992 2月, In: Experimental and Molecular Pathology. 56, 1, p. 60-69 10 p.

研究成果: Article › 査読

74 被引用数 (Scopus)

Effect of rebamipide on H. pylori-associated gastric mucosal injury in Mongolian gerbils

Suzuki, H., Mori, M., Kai, A., Suzuki, M., Suematsu, M., Miura, S. & Ishii, H., 1998 10月 3, In: Digestive Diseases and Sciences. 43, 9 SUPPL., p. 181S-187S

研究成果: Article › 査読

13 被引用数 (Scopus)

Effects of serine protease inhibitors on oxyradical burst from phagocytizing neutrophils--analysis by chemiluminescence counting and its microscopic imaging.

Suematsu, M., Houzawa, S., Miura, S., Nagata, H., Kitahora, T., Morishita, T., Oshio, C. & Tsuchiya, M., 1989 7月, In: Journal of bioluminescence and chemiluminescence. 4, 1, p. 531-534 4 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Efficacy of 10-day Sitafloxacin-Containing Third-Line Rescue Therapies for Helicobacter pylori Strains Containing the gyrA Mutation

Mori, H., Suzuki, H., Matsuzaki, J., Tsugawa, H., Fukuhara, S., Miyoshi, S., Hirata, K., Seino, T., Matsushita, M., Masaoka, T. & Kanai, T., 2016 8月 1, In: Helicobacter. 21, 4, p. 286-294 9 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Electron microscopic demonstration of free calcium in the capillary endothelium in comparison with computerized image analysis using Fura-2 AM

Oda, M., Watanabe, N., Komatsu, H., Suematsu, M., Kaneko, K., Azuma, T., Nishizaki, Y., Nakamura, M., Fujiwara, T. & Tsuchiya, M., 1988 1月 1, In: Journal of Clinical Electron Microscopy. 21, 5-6, p. 558-559 2 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Electrophysiological characterization of cultured hepatic stellate cells in rats

Kashiwagi, S., Suematsu, M., Wakabayashi, Y., Kawada, N., Tachibana, M., Koizumi, A., Inoue, M., Ishimura, Y. & Kaneko, A., 1997 4月, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 272, 4 35-4, p. G742-G750

研究成果: Article › 査読

22 被引用数 (Scopus)

Elucidation of apoptosis induced by serum deprivation in cultured conjunctival epithelial cells

Higuchi, A., Shimmura, S., Takeuchi, T., Suematsu, M. & Tsubota, K., 2006 6月, In: British Journal of Ophthalmology. 90, 6, p. 760-764 5 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

Endogenous carbon monoxide suppression stimulates bile acid-dependent biliary transport in perfused rat liver

Sano, T., Shiomi, M., Wakabayashi, Y., Shinoda, Y., Goda, N., Yamaguchi, T., Nimura, Y., Ishimura, Y. & Suematsu, M., 1997 5月, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 272, 5 35-5, p. G1268-G1275

研究成果: Article › 査読

40 被引用数 (Scopus)

Endogenous prostaglandin D₂ and its metabolites protect the heart against ischemia-reperfusion injury by activating Nrf2

Katsumata, Y., Shinmura, K., Sugiura, Y., Tohyama, S., Matsuhashi, T., Ito, H., Yan, X., Ito, K., Yuasa, S., Ieda, M., Urade, Y., Suematsu, M., Fukuda, K. & Sano, M., 2014 1月, In: Hypertension. 63, 1, p. 80-87 8 p.

研究成果: Article › 査読

64 被引用数 (Scopus)

Endothelial-derived nitric oxide preserves anticoagulant heparan sulfate expression in cultured porcine aortic endothelial cells

Irokawa, M., Nishinaga, M., Ikeda, U., Shinoda, Y., Suematsu, M., Gouda, N., Ishimura, Y. & Shimada, K., 1997 11月 1, In: Atherosclerosis. 135, 1, p. 9-17 9 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Endothelin B receptor-mediated protection against anoxia-reoxygenation injury in perfused rat liver: Nitric oxide-dependent and-independent mechanisms

Taniai, H., Suematsu, M., Susuki, T., Norimizu, S., Hori, R., Ishimura, Y. & Nimura, Y., 2001, In: Hepatology. 33, 4, p. 894-901 8 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Energy management by enhanced glycolysis in G₁-phase in human colon cancer cells in vitro and in vivo

Bao, Y., Mukai, K., Hishiki, T., Kubo, A., Ohmura, M., Sugiura, Y., Matsuura, T., Nagahata, Y., Hayakawa, N., Yamamoto, T., Fukuda, R., Saya, H., Suematsu, M. & Minamishima, Y. A., 2013 9月, In: Molecular Cancer Research. 11, 9, p. 973-985 13 p.

研究成果: Article › 査読

47 被引用数 (Scopus)

Enhanced bacterial efflux system is the first step to the development of metronidazole resistance in Helicobacter pylori

Tsugawa, H., Suzuki, H., Muraoka, H., Ikeda, F., Hirata, K., Matsuzaki, J., Saito, Y. & Hibi, T., 2011 1月 14, In: Biochemical and Biophysical Research Communications. 404, 2, p. 656-660 5 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Enhanced lymphocyte interaction in postcapillary venules of Peyer's patches during fat absorption in rats

Tsuzuki, Y., Miura, S., Kurose, I., Suematsu, M., Higuchi, H., Shigematsu, T., Kimura, H., Serizawa, H., Hokari, R., Akiba, Y., Yagita, H., Okumura, K., Tso, P., Granger, D. N. & Ishii, H., 1997, In: Gastroenterology. 112, 3, p. 813-825 13 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Enhancement of amoxicillin resistance after unsuccessful Helicobacter pylori eradication

Nishizawa, T., Suzuki, H., Tsugawa, H., Muraoka, H., Matsuzaki, J., Hirata, K., Ikeda, F., Takahashi, M. & Hibi, T., 2011 6月, In: Antimicrobial Agents and Chemotherapy. 55, 6, p. 3012-3014 3 p.

研究成果: Article › 査読

36 被引用数 (Scopus)

Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying

Fukuhara, S., Masaoka, T., Nishimura, S., Nakamura, M., Matsuzaki, J., Tsugawa, H., Miyoshi, S., Mori, H., Kawase, S., Shibata, S., Okano, H., Kanai, T. & Suzuki, H., 2017 12月 1, In: Digestive Diseases and Sciences. 62, 12, p. 3359-3369 11 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

Kobayashi, H., Morikawa, T., Okinaga, A., Hamano, F., Hashidate-Yoshida, T., Watanuki, S., Hishikawa, D., Shindou, H., Arai, F., Kabe, Y., Suematsu, M., Shimizu, T. & Takubo, K., 2019 7月 2, In: Cell Reports. 28, 1, p. 145-158.e9

研究成果: Article › 査読

Open Access

32 被引用数 (Scopus)

Epidermal cell turnover across tight junctions based on Kelvin’s tetrakaidecahedron cell shape

Yokouchi, M., Atsugi, T., Van Logtestijn, M., Tanaka, R. J., Kajimura, M., Suematsu, M., Furuse, M., Amagai, M. & Kubo, A., 2016 11月 29, In: eLife. 5, NOVEMBER2016, e19593.

研究成果: Article › 査読

Open Access

55 被引用数 (Scopus)

ERK and p38 MAPK, but not NF-κB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts

Sano, M., Fukuda, K., Sato, T., Kawaguchi, H., Suematsu, M., Matsuda, S., Koyasu, S., Matsui, H., Yamauchi-Takihara, K., Harada, M., Saito, Y. & Ogawa, S., 2001 10月 12, In: Circulation research. 89, 8, p. 661-669 9 p.

研究成果: Article › 査読

Open Access

259 被引用数 (Scopus)

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