研究成果 1985 2020

フィルター
Article
2020

Loss of autophagy impairs physiological steatosis by accumulation of NCoR1

Takahashi, S. S., Sou, Y. S., Saito, T., Kuma, A., Yabe, T., Sugiura, Y., Lee, H. C., Suematsu, M., Yokomizo, T., Koike, M., Terai, S., Mizushima, N., Waguri, S. & Komatsu, M., 2020 1 1, : : Life Science Alliance. 3, 1, e201900513.

研究成果: Article

公開
Nuclear Receptor Co-Repressor 1
autophagy
Autophagy
lipid
droplet

Quantitative MALDI-MS/MS assay for serum cortisol through charged derivatization

Nakamura, M., Moritsuna, M., Yuda, K., Fujimura, S., Sugiura, Y., Shimma, S., Nishimoto, K., Nishikawa, T., Suematsu, M., Ogawa, S. & Higashi, T., 2020 1 30, : : Journal of Pharmaceutical and Biomedical Analysis. 178, 112912.

研究成果: Article

Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Hydrocortisone
Assays
Serum
Electrospray ionization
2019
74 引用 (Scopus)

A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

Tanoue, T., Morita, S., Plichta, D. R., Skelly, A. N., Suda, W., Sugiura, Y., Narushima, S., Vlamakis, H., Motoo, I., Sugita, K., Shiota, A., Takeshita, K., Yasuma-Mitobe, K., Riethmacher, D., Kaisho, T., Norman, J. M., Mucida, D., Suematsu, M., Yaguchi, T., Bucci, V. および8人, Inoue, T., Kawakami, Y., Olle, B., Roberts, B., Hattori, M., Xavier, R. J., Atarashi, K. & Honda, K., 2019 1 31, : : Nature. 565, 7741, p. 600-605 6 p.

研究成果: Article

Immunity
T-Lymphocytes
Listeriosis
Histocompatibility
Microbiota
4 引用 (Scopus)

Application of high-performance magnetic nanobeads to biological sensing devices

Kabe, Y., Sakamoto, S., Hatakeyama, M., Yamaguchi, Y., Suematsu, M., Itonaga, M. & Handa, H., 2019 1 1, (Accepted/In press) : : Analytical and Bioanalytical Chemistry.

研究成果: Article

Exosomes
Equipment and Supplies
Technology
Immunoassay
Drug Receptors

A thin layer of sucrose octasulfate protects the oesophageal mucosal epithelium in reflux oesophagitis

Hayakawa, T., Kawasaki, S., Hirayama, Y., Tsutsui, T., Sugiyama, E., Adachi, K., Kon, R., Suematsu, M. & Sugiura, Y., 2019 12 1, : : Scientific reports. 9, 1, 3559.

研究成果: Article

公開
Peptic Esophagitis
Sucralfate
Epithelium
Gastric Juice
Pepsin A
16 引用 (Scopus)

Autophagy regulates lipid metabolism through selective turnover of NCoR1

Saito, T., Kuma, A., Sugiura, Y., Ichimura, Y., Obata, M., Kitamura, H., Okuda, S., Lee, H. C., Ikeda, K., Kanegae, Y., Saito, I., Auwerx, J., Motohashi, H., Suematsu, M., Soga, T., Yokomizo, T., Waguri, S., Mizushima, N. & Komatsu, M., 2019 12 1, : : Nature communications. 10, 1, 1567.

研究成果: Article

公開
Nuclear Receptor Co-Repressor 1
lipid metabolism
Peroxisome Proliferator-Activated Receptors
Autophagy
Lipid Metabolism
2 引用 (Scopus)

Cancer Stem-Cell Marker CD44v9-Positive Cells Arise From Helicobacter pylori–Infected CAPZA1-Overexpressing Cells

Tsugawa, H., Kato, C., Mori, H., Matsuzaki, J., Kameyama, K., Saya, H., Hatakeyama, M., Suematsu, M. & Suzuki, H., 2019 1 1, : : CMGH. 8, 3, p. 319-334 16 p.

研究成果: Article

公開
Helicobacter
Neoplastic Stem Cells
Catenins
Protein Splicing
Histones

Dendropanax morbiferus leaf extract facilitates oligodendrocyte development

Kim, J. Y., Yoon, J. Y., Sugiura, Y., Lee, S. K., Park, J. D., Song, G. J. & Yang, H. J., 2019 6 1, : : Royal Society Open Science. 6, 6, 190266.

研究成果: Article

公開
Oligodendroglia
Cell Culture Techniques
Multiple Sclerosis
Anti-Inflammatory Agents
Up-Regulation
1 引用 (Scopus)

Detection of a High-Turnover Serotonin Circuit in the Mouse Brain Using Mass Spectrometry Imaging

Sugiyama, E., Guerrini, M. M., Honda, K., Hattori, Y., Abe, M., Källback, P., Andrén, P. E., Tanaka, K. F., Setou, M., Fagarasan, S., Suematsu, M. & Sugiura, Y., 2019 10 25, : : iScience. 20, p. 359-372 14 p.

研究成果: Article

公開
Mass Spectrometry
Serotonin
Midline Thalamic Nuclei
Brain
Norepinephrine

Environmental Optimization Enables Maintenance of Quiescent Hematopoietic Stem Cells Ex Vivo

Kobayashi, H., Morikawa, T., Okinaga, A., Hamano, F., Hashidate-Yoshida, T., Watanuki, S., Hishikawa, D., Shindou, H., Arai, F., Kabe, Y., Suematsu, M., Shimizu, T. & Takubo, K., 2019 7 2, : : Cell Reports. 28, 1, p. 145-158.e9

研究成果: Article

公開
Hematopoietic Stem Cells
Stem cells
Maintenance
Fatty Acids
Cell culture
2 引用 (Scopus)

Identification of a binding protein for sesamin and characterization of its roles in plant growth

Tera, M., Koyama, T., Murata, J., Furukawa, A., Mori, S., Azuma, T., Watanabe, T., Hori, K., Okazawa, A., Kabe, Y., Suematsu, M., Satake, H., Ono, E. & Horikawa, M., 2019 12 1, : : Scientific reports. 9, 1, 8631.

研究成果: Article

公開
Carrier Proteins
Growth
Sesamum
sesamin
Lignans
2 引用 (Scopus)
Cytochrome P-450 CYP11B2
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Aldosterone
Immunohistochemistry
Hyperaldosteronism
6 引用 (Scopus)

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

Kofuji, S., Hirayama, A., Eberhardt, A. O., Kawaguchi, R., Sugiura, Y., Sampetrean, O., Ikeda, Y., Warren, M., Sakamoto, N., Kitahara, S., Yoshino, H., Yamashita, D., Sumita, K., Wolfe, K., Lange, L., Ikeda, S., Shimada, H., Minami, N., Malhotra, A., Morioka, S. および37人, Ban, Y., Asano, M., Flanary, V. L., Ramkissoon, A., Chow, L. M. L., Kiyokawa, J., Mashimo, T., Lucey, G., Mareninov, S., Ozawa, T., Onishi, N., Okumura, K., Terakawa, J., Daikoku, T., Wise-Draper, T., Majd, N., Kofuji, K., Sasaki, M., Mori, M., Kanemura, Y., Smith, E. P., Anastasiou, D., Wakimoto, H., Holland, E. C., Yong, W. H., Horbinski, C., Nakano, I., DeBerardinis, R. J., Bachoo, R. M., Mischel, P. S., Yasui, W., Suematsu, M., Saya, H., Soga, T., Grummt, I., Bierhoff, H. & Sasaki, A. T., 2019 8 1, : : Nature Cell Biology. 21, 8, p. 1003-1014 12 p.

研究成果: Article

IMP Dehydrogenase
Glioblastoma
Carcinogenesis
Transfer RNA
Guanine Nucleotides
3 引用 (Scopus)

Increased cytotoxicity of herpes simplex virus thymidine kinase expression in human induced pluripotent stem cells

Iwasawa, C., Tamura, R., Sugiura, Y., Suzuki, S., Kuzumaki, N., Narita, M., Suematsu, M., Nakamura, M., Yoshida, K., Toda, M., Okano, H. & Miyoshi, H., 2019 2 2, : : International Journal of Molecular Sciences. 20, 4, 810.

研究成果: Article

公開
Induced Pluripotent Stem Cells
thymidine
Thymidine Kinase
stem cells
Human Herpesvirus 1
1 引用 (Scopus)

Lectin microarray analyses reveal host cell-specific glycan profiles of the hemagglutinins of influenza A viruses

Hiono, T., Matsuda, A., Wagatsuma, T., Okamatsu, M., Sakoda, Y. & Kuno, A., 2019 1 15, : : Virology. 527, p. 132-140 9 p.

研究成果: Article

Influenza A virus
Hemagglutinins
Microarray Analysis
Lectins
Polysaccharides
2 引用 (Scopus)

Mechanical allodynia induced by optogenetic sensory nerve excitation activates dopamine signaling and metabolism in medial nucleus accumbens

Sugiyama, E., Kondo, T., Kuzumaki, N., Honda, K., Yamanaka, A., Narita, M., Suematsu, M. & Sugiura, Y., 2019 10 1, : : Neurochemistry International. 129, 104494.

研究成果: Article

公開
Optogenetics
Hyperalgesia
Nucleus Accumbens
Dopamine
Pain

Neutrophil-activating Protein Polymorphism of Helicobacter pylori Determines the Host Risk of Dyspepsia

Matsuzaki, J., Tsugawa, H., Kashiwazaki, Y., Mori, H., Yamamoto, Y., Kameyama, H., Masaoka, T., Kanai, T. & Suzuki, H., 2019 1 1, : : CMGH. 8, 2, p. 295-297.e6

研究成果: Article

公開
Dyspepsia
Helicobacter pylori neutrophil-activating protein A

Small molecules assisting eggshell calcium dissolution for embryonic bone formation

Ito, T., Kato, S., Kubo, A., Suematsu, M., Nakata, M. & Saikawa, Y., 2019 1 1, (Accepted/In press) : : Tetrahedron. 130854.

研究成果: Article

Egg Shell
Calcium Carbonate
Osteogenesis
Bone
Dissolution
1 引用 (Scopus)

Tandem Mass Spectrometry Imaging Reveals Distinct Accumulation Patterns of Steroid Structural Isomers in Human Adrenal Glands

Takeo, E., Sugiura, Y., Uemura, T., Nishimoto, K., Yasuda, M., Sugiyama, E., Ohtsuki, S., Higashi, T., Nishikawa, T., Suematsu, M., Fukusaki, E. & Shimma, S., 2019 1 1, : : Analytical chemistry.

研究成果: Article

Aldosterone
Isomers
Mass spectrometry
Steroids
Imaging techniques

Xanthine oxidase inhibitor ameliorates postischemic renal injury in mice by promoting resynthesis of adenine nucleotides

Fujii, K., Kubo, A., Miyashita, K., Sato, M., Hagiwara, A., Inoue, H., Ryuzaki, M., Tamaki, M., Hishiki, T., Hayakawa, N., Kabe, Y., Itoh, H. & Suematsu, M., 2019 11 14, : : JCI Insight. 4, 22, e124816.

研究成果: Article

公開
Adenine Nucleotides
Xanthine Oxidase
Kidney
Ischemia
Wounds and Injuries
2018
6 引用 (Scopus)

Aldosterone and 18-Oxocortisol Coaccumulation in Aldosterone-Producing Lesions

Sugiura, Y., Takeo, E., Shimma, S., Yokota, M., Higashi, T., Seki, T., Mizuno, Y., Oya, M., Kosaka, T., Omura, M., Nishikawa, T., Suematsu, M. & Nishimoto, K., 2018 12 1, : : Hypertension (Dallas, Tex. : 1979). 72, 6, p. 1345-1354 10 p.

研究成果: Article

Aldosterone
Hyperaldosteronism
Adenoma
Cytochrome P-450 CYP11B2
18-oxocortisol
4 引用 (Scopus)
Aldosterone
Serum
Sampling
Hyperaldosteronism
Assays
11 引用 (Scopus)

Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor–Initiating Stem Cell–Like Cells Resistant to mTORC1 Inhibition

Wu, R., Murali, R., Kabe, Y., French, S. W., Chiang, Y. M., Liu, S., Sher, L., Wang, C. C., Louie, S. & Tsukamoto, H., 2018 11 1, : : Hepatology. 68, 5, p. 1726-1740 15 p.

研究成果: Article

GTP Phosphohydrolases
Autophagy
Sirolimus
Stem Cells
Liver
2 引用 (Scopus)
Entamoeba histolytica
Metabolomics
Coenzymes
Molecular Biology
Parasites
4 引用 (Scopus)

CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy

Tsugawa, H., Mori, H., Matsuzaki, J., Sato, A., Saito, Y., Imoto, M., Suematsu, M. & Suzuki, H., 2018 1 1, (Accepted/In press) : : Autophagy.

研究成果: Article

Lysosomal-Associated Membrane Protein 1
Low Density Lipoprotein Receptor-Related Protein-1
Autophagy
Helicobacter pylori
Actins
2 引用 (Scopus)

Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target

Nurkanto, A., Jeelani, G., Yamamoto, T., Naito, Y., Hishiki, T., Mori, M., Suematsu, M., Shiomi, K., Hashimoto, T. & Nozaki, T., 2018 4 1, : : International Journal for Parasitology: Drugs and Drug Resistance. 8, 1, p. 125-136 12 p.

研究成果: Article

Entamoeba histolytica
Coenzyme A
Pharmaceutical Preparations
Enzymes
Amebiasis
4 引用 (Scopus)

Cholesterol sulfate is a DOCK2 inhibitor that mediates tissue-specific immune evasion in the eye

Sakurai, T., Uruno, T., Sugiura, Y., Tatsuguchi, T., Yamamura, K., Ushijima, M., Hattori, Y., Kukimoto-Niino, M., Mishima-Tsumagari, C., Watanabe, M., Suematsu, M. & Fuku, Y., 2018 7 31, : : Science Signaling. 11, 541, eaao4874.

研究成果: Article

Immune Evasion
Cytokinesis
Tissue
Guanine Nucleotide Exchange Factors
Proteins
8 引用 (Scopus)

Development of a highly sensitive device for counting the number of disease-specific exosomes in human sera

Kabe, Y., Suematsu, M., Sakamoto, S., Hirai, M., Koike, I., Hishiki, T., Matsuda, A., Hasegawa, Y., Tsujita, K., Ono, M., Minegishi, N., Hozawa, A., Murakami, Y., Kubo, M., Itonaga, M. & Handa, H., 2018 10 1, : : Clinical Chemistry. 64, 10, p. 1463-1473 11 p.

研究成果: Article

Exosomes
Equipment and Supplies
CD147 Antigens
Serum
Flow cytometry
7 引用 (Scopus)

Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system

Watanabe, M., Sugiura, Y., Sugiyama, E., Narita, M., Navratilova, E., Kondo, T., Uchiyama, N., Yamanaka, A., Kuzumaki, N., Porreca, F. & Narita, M., 2018 1 1, : : Molecular Pain. 14

研究成果: Article

Microdialysis
Nucleus Accumbens
Mass Spectrometry
Pain
Neurotransmitter Agents
22 引用 (Scopus)

Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival

Shiota, M., Naya, M., Yamamoto, T., Hishiki, T., Tani, T., Takahashi, H., Kubo, A., Koike, D., Itoh, M., Ohmura, M., Kabe, Y., Sugiura, Y., Hiraoka, N., Morikawa, T., Takubo, K., Suina, K., Nagashima, H., Sampetrean, O., Nagano, O., Saya, H. および3人, Yamazoe, S., Watanabe, H. & Suematsu, M., 2018 12 1, : : Nature Communications. 9, 1, 1561.

研究成果: Article

Raman Spectrum Analysis
Oxidants
Gold
Raman spectroscopy
tumors
4 引用 (Scopus)

Inhibiting xCT improves 5-fluorouracil resistance of gastric cancer induced by CD44 variant 9 expression

Miyoshi, S., Tsugawa, H., Matsuzaki, J., Hirata, K., Mori, H., Saya, H., Kanai, T. & Suzuki, H., 2018 11 1, : : Anticancer Research. 38, 11, p. 6163-6170 8 p.

研究成果: Article

Fluorouracil
Stomach Neoplasms
Neoplastic Stem Cells
Antiporters
Drug Therapy
15 引用 (Scopus)

Optogenetic astrocyte activation evokes BOLD fMRI response with oxygen consumption without neuronal activity modulation

Takata, N., Sugiura, Y., Yoshida, K., Koizumi, M., Hiroshi, N., Honda, K., Yano, R., Komaki, Y., Matsui, K., Suematsu, M., Mimura, M., Okano, H. & Tanaka, K., 2018 9 1, : : GLIA. 66, 9, p. 2013-2023 11 p.

研究成果: Article

Optogenetics
Oxygen Consumption
Astrocytes
Magnetic Resonance Imaging
Acetylcarnitine
27 引用 (Scopus)

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth

Morita, M., Sato, T., Nomura, M., Sakamoto, Y., Inoue, Y., Tanaka, R., Ito, S., Kurosawa, K., Yamaguchi, K., Sugiura, Y., Takizaki, H., Yamashita, Y., Katakura, R., Sato, I., Kawai, M., Okada, Y., Watanabe, H., Kondoh, G., Matsumoto, S., Kishimoto, A. および12人, Obata, M., Matsumoto, M., Fukuhara, T., Motohashi, H., Suematsu, M., Komatsu, M., Nakayama, K. I., Watanabe, T., Soga, T., Shima, H., Maemondo, M. & Tanuma, N., 2018 3 12, : : Cancer Cell. 33, 3, p. 355-367.e7

研究成果: Article

Small Cell Lung Carcinoma
Growth
Neoplasms
Protein Isoforms
Neuroendocrine Tumors
2 引用 (Scopus)
Brain Ischemia
Brain
Mass Spectrometry
Spectroscopy
Imaging techniques
18 引用 (Scopus)

Sodium-glucose cotransporter 2 inhibition normalizes glucose metabolism and suppresses oxidative stress in the kidneys of diabetic mice

Tanaka, S., Sugiura, Y., Saito, H., Sugahara, M., Higashijima, Y., Yamaguchi, J., Inagi, R., Suematsu, M., Nangaku, M. & Tanaka, T., 2018 11 1, : : Kidney International. 94, 5, p. 912-925 14 p.

研究成果: Article

Sodium-Glucose Transport Proteins
Oxidative Stress
Kidney
Glucose
Citric Acid Cycle
Glycols
Biomarkers
Polysaccharides
2017
6 引用 (Scopus)

Arl8b is required for lysosomal degradation of maternal proteins in the visceral yolk sac endoderm of mouse embryos

Oka, M., Hashimoto, K., Yamaguchi, Y., Saitoh, S. I., Sugiura, Y., Motoi, Y., Honda, K., Kikko, Y., Ohata, S., Suematsu, M., Miura, M., Miyake, K., Katada, T. & Kontani, K., 2017, : : Journal of Cell Science. 130, 20, p. 3568-3577 10 p.

研究成果: Article

Yolk Sac
Endoderm
Proteolysis
Embryonic Structures
Mothers
4 引用 (Scopus)

Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying

Fukuhara, S., Masaoka, T., Nishimura, S., Nakamura, M., Matsuzaki, J., Tsugawa, H., Miyoshi, S., Mori, H., Kawase, S., Shibata, S., Okano, H., Kanai, T. & Suzuki, H., 2017 11 2, (Accepted/In press) : : Digestive Diseases and Sciences. p. 1-11 11 p.

研究成果: Article

Gastric Emptying
Apolipoproteins E
Neuroglia
Knockout Mice
Glial Fibrillary Acidic Protein
31 引用 (Scopus)

Metabolic shift induced by systemic activation of T cells in PD-1-deficient mice perturbs brain monoamines and emotional behavior

Miyajima, M., Zhang, B., Sugiura, Y., Sonomura, K., Guerrini, M. M., Tsutsui, Y., Maruya, M., Vogelzang, A., Chamoto, K., Honda, K., Hikida, T., Ito, S., Qin, H., Sanuki, R., Suzuki, K., Furukawa, T., Ishihama, Y., Matsuda, F., Suematsu, M., Honjo, T. および1人, Fagarasan, S., 2017 11 16, : : Nature Immunology. 18, 12, p. 1342-1352 11 p.

研究成果: Article

T-Lymphocytes
Brain
Amino Acids
Programmed Cell Death 1 Receptor
Immune System
6 引用 (Scopus)

Placental labyrinth formation in mice requires endothelial FLRT2/UNC5B signaling

Tai-Nagara, I., Yoshikawa, Y., Numata, N., Ando, T., Okabe, K., Sugiura, Y., Ieda, M., Takakura, N., Nakagawa, O., Zhou, B., Okabayashi, K., Suematsu, M., Kitagawa, Y., Bastmeyer, M., Sato, K., Klein, R., Navankasattusas, S., Li, D. Y., Yamagishi, S. & Kubota, Y., 2017, : : Development (Cambridge). 144, 13, p. 2392-2401 10 p.

研究成果: Article

Inner Ear
Fibronectins
Leucine
Endothelial Cells
Proteins
1 引用 (Scopus)
Oligodendroglia
Thyroid Hormones
Adult Stem Cells
Core Binding Factor Alpha 2 Subunit
Cyclin-Dependent Kinase Inhibitor p15
19 引用 (Scopus)

Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching

Miyazawa, H., Yamaguchi, Y., Sugiura, Y., Honda, K., Kondo, K., Matsuda, F., Yamamoto, T., Suematsu, M. & Miura, M., 2017, : : Journal of Cell Science. 130, 2, p. 63-73 11 p.

研究成果: Article

Fructose-Bisphosphate Aldolase
Embryonic Structures
Energy Metabolism
Glucose
Lactic Acid
20 引用 (Scopus)

Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to PGRMC1

Pati, M. L., Groza, D., Riganti, C., Kopecka, J., Niso, M., Berardi, F., Hager, S., Heffeter, P., Hirai, M., Tsugawa, H., Kabe, Y., Suematsu, M. & Abate, C., 2017 3 1, : : Pharmacological Research. 117, p. 67-74 8 p.

研究成果: Article

Progesterone Receptors
Ligands
Membranes
Proteins
Heme
10 引用 (Scopus)

Somatic KCNJ5 mutation occurring early in adrenal development may cause a novel form of juvenile primary aldosteronism

Tamura, A., Nishimoto, K., Seki, T., Matsuzawa, Y., Saito, J., Omura, M., Gomez-Sanchez, C. E., Makita, K., Matsui, S., Moriya, N., Inoue, A., Nagata, M., Sasano, H., Nakamura, Y., Yamazaki, Y., Kabe, Y., Mukai, K., Kosaka, T., Oya, M., Suematsu, S. および1人, Nishikawa, T., 2017 2 5, : : Molecular and Cellular Endocrinology. 441, p. 134-139 6 p.

研究成果: Article

Hyperaldosteronism
Aldosterone
Cytochrome P-450 CYP11B2
Adrenal Glands
Mutation
29 引用 (Scopus)

Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6

Lai, K. K. Y., Kweon, S. M., Chi, F., Hwang, E., Kabe, Y., Higashiyama, R., Qin, L., Yan, R., Wu, R. P., Lai, K., Fujii, N., French, S., Xu, J., Wang, J. Y., Murali, R., Mishra, L., Lee, J. S., Ntambi, J. M. & Tsukamoto, H., 2017 5 1, : : Gastroenterology. 152, 6, p. 1477-1491 15 p.

研究成果: Article

Low Density Lipoprotein Receptor-Related Protein-6
Low Density Lipoprotein Receptor-Related Protein-5
Stearoyl-CoA Desaturase
Liver Cirrhosis
Hepatic Stellate Cells
3 引用 (Scopus)

Targeting oxygen-sensing prolyl hydroxylase for metformin-associated lactic acidosis treatment

Toramaru, T., Suhara, T., Hayakawa, N., Nakamura, T., Kubo, A., Minamishima, S., Yamaguchi, K., Hishiki, T., Morisaki, H., Suematsu, M. & Minamishima, Y. A., 2017 8 1, : : Molecular and Cellular Biology. 37, 16, e00248-17.

研究成果: Article

Prolyl Hydroxylases
Lactic Acidosis
Metformin
Oxygen
Prolyl-Hydroxylase Inhibitors
3 引用 (Scopus)

Utilizing mass spectrometry imaging to map the thyroid hormones triiodothyronine and thyroxine in Xenopus tropicalis tadpoles

Goto-Inoue, N., Sato, T., Morisasa, M., Kashiwagi, A., Kashiwagi, K., Sugiura, Y., Sugiyama, E., Suematsu, M. & Mori, T., 2017 12 15, (Accepted/In press) : : Analytical and Bioanalytical Chemistry. p. 1-8 8 p.

研究成果: Article

Triiodothyronine
Xenopus
Thyroxine
Thyroid Hormones
Mass spectrometry
2016
5 引用 (Scopus)

Alteration of matrix metalloproteinase-3 O-glycan structure as a biomarker for disease activity of rheumatoid arthritis

Takeshita, M., Kuno, A., Suzuki, K., Matsuda, A., Shimazaki, H., Nakagawa, T., Otomo, Y., Kabe, Y., Suematsu, M., Narimatsu, H. & Takeuchi, T., 2016 5 21, : : Arthritis Research and Therapy. 18, 1, 112.

研究成果: Article

Matrix Metalloproteinase 3
Polysaccharides
Rheumatoid Arthritis
Biomarkers
Agrocybe
2 引用 (Scopus)

Disorganized Steroidogenesis in Adrenocortical Carcinoma, a Case Study

Uchida, T., Nishimoto, K., Fukumura, Y., Asahina, M., Goto, H., Kawano, Y., Shimizu, F., Tsujimura, A., Seki, T., Mukai, K., Kabe, Y., Suematsu, M., Gomez-Sanchez, C. E., Yao, T., Horie, S. & Watada, H., 2016 7 18, (Accepted/In press) : : Endocrine Pathology. p. 1-9 9 p.

研究成果: Article

Adrenocortical Carcinoma
Steroid 11-beta-Hydroxylase
Cytochrome P-450 CYP11B2
Hydrocortisone
Aldosterone
20 引用 (Scopus)

Efficacy of 10-day Sitafloxacin-Containing Third-Line Rescue Therapies for Helicobacter pylori Strains Containing the gyrA Mutation

Mori, H., Suzuki, H., Matsuzaki, J., Tsugawa, H., Fukuhara, S., Miyoshi, S., Hirata, K., Seino, T., Matsushita, M., Masaoka, T. & Kanai, T., 2016 8 1, : : Helicobacter. 21, 4, p. 286-294 9 p.

研究成果: Article

Helicobacter pylori
Mutation
Esomeprazole
Amoxicillin
Metronidazole