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A Bioartificial Liver Device Secreting Interleukin-1 Receptor Antagonist for the Treatment of Hepatic Failure in Rats

Shinoda, M., Tilles, A. W., Kobayashi, N., Wakabayashi, G., Takayanagi, A., Totsugawa, T., Harada, H., Obara, H., Suganuma, K., Berthiaume, F., Shimazu, M., Shimizu, N., Tanaka, N., Kitajima, M., Tompkins, R. G., Toner, M. & Yarmush, M. L., 2007 1, : : Journal of Surgical Research. 137, 1, p. 130-140 11 p.

研究成果: Article

20 引用 (Scopus)

A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3

Shibuya, K., Obayashi, I., Asakawa, S., Minoshima, S., Kudoh, J. & Shimizu, N., 2004 4, : : Genomics. 83, 4, p. 679-693 15 p.

研究成果: Article

28 引用 (Scopus)

Adenovirus-mediated gene transduction of truncated IκBα enhances radiosensitivity in human colon cancer cells

Mukogawa, T., Koyama, F., Tachibana, M., Takayanagi, A., Shimizu, N., Fujii, H., Ueno, M., Matsumoto, H., Takeuchi, T. & Nakajima, Y., 2003 8 1, : : Cancer science. 94, 8, p. 745-750 6 p.

研究成果: Article

28 引用 (Scopus)

A direct role for Hsp90 in pre-RISC formation in Drosophila

Miyoshi, T., Takeuchi, A., Siomi, H. & Siomi, M. C., 2010 8, : : Nature Structural and Molecular Biology. 17, 8, p. 1024-1026 3 p.

研究成果: Article

104 引用 (Scopus)

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

Ishizuka, A., Siomi, M. C. & Siomi, H., 2002 10 1, : : Genes and Development. 16, 19, p. 2497-2508 12 p.

研究成果: Article

465 引用 (Scopus)

A microRNA regulatory mechanism of osteoblast differentiation

Inose, H., Ochi, H., Kimura, A., Fujita, K., Xu, R., Sato, S., Iwasaki, M., Sunamura, S., Takeuchi, Y., Fukumoto, S., Saito, K., Nakamura, T., Siomi, H., Ito, H., Arai, Y., Shinomiya, K. I. & Takeda, S., 2009 12 8, : : Proceedings of the National Academy of Sciences of the United States of America. 106, 49, p. 20794-20799 6 p.

研究成果: Article

210 引用 (Scopus)

A novel gene delivery system using EGF receptor-mediated endocytosis

Chen, J., Gamou, S., Takayanagi, A. & Shimizu, N., 1994 1 31, : : FEBS Letters. 338, 2, p. 167-169 3 p.

研究成果: Article

104 引用 (Scopus)

A nuclear localization domain in the hnRNP A1 protein

Siomi, H. & Dreyfuss, G., 1995 5, : : Journal of Cell Biology. 129, 3, p. 551-560 10 p.

研究成果: Article

417 引用 (Scopus)

A physical map of the human genome

McPherson, J. D., Marra, M., Hillier, L. D., Waterston, R. H., Chinwalla, A., Wallis, J., Sekhon, M., Wylie, K., Mardis, E. R., Wilson, R. K., Fulton, R., Kucaba, T. A., Wagner-McPherson, C., Barbazuk, W. B., Gregory, S. G., Humphray, S. J., French, L., Evans, R. S., Bethel, G., Whittaker, A. および93人, Holden, J. L., McCann, O. T., Dunham, A., Soderlund, C., Scott, C. E., Bentley, D. R., Schuler, G., Chen, H. C., Jang, W., Green, E. D., Idol, J. R., Maduro, V. V. B., Montgomery, K. T., Lee, E., Miller, A., Emerling, S., Kucherlapati, R., Gibbs, R., Scherer, S., Gorrell, J. H., Sodergren, E., Clerc-Blankenburg, K., Tabor, P., Naylor, S., Garcia, D., de Jong, J., Catanese, J. J., Nowak, N., Osoegawa, K., Qin, S., Rowen, L., Madan, A., Dors, M., Hood, L., Trask, B., Friedman, C., Massa, H., Cheung, V. G., Kirsch, I. R., Reid, T., Yonescu, R., Weissenbach, J., Bruls, T., Heilig, R., Branscomb, E., Olsen, A., Doggett, N., Cheng, J. F., Hawkins, T., Myers, R. M., Shang, J., Ramirez, L., Schmutz, J., Velasquez, O., Dixon, K., Stone, N. E., Cox, D. R., Haussler, D., Kent, W. J., Furey, T., Rogic, S., Kennedy, S., Jones, S., Rosenthal, A., Wen, G., Schilhabel, M., Gloeckner, G., Nyakatura, G., Siebert, R., Schlegelberger, B., Korenberg, J., Chen, X. N., Fujiyama, A., Hattori, M., Toyoda, A., Yada, T., Park, H. S., Sakaki, Y., Shimizu, N., Asakawa, S., Kawasaki, K., Sasaki, T., Shintani, A., Shimizu, A., Shibuya, K., Kudoh, J., Minoshima, S., Ramser, J., Seranski, P., Hoff, C., Poustka, A., Reinhardt, R. & Lehrach, H., 2001 2 15, : : Nature. 409, 6822, p. 934-941 8 p.

研究成果: Article

670 引用 (Scopus)

A potential link between transgene silencing and poly(A) tails

Siomi, M. C., Tsukumo, H., Ishizuka, A., Nagami, T. & Siomi, H., 2005 7, : : RNA. 11, 7, p. 1004-1011 8 p.

研究成果: Article

13 引用 (Scopus)

A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila

Saito, K., Inagaki, S., Mituyama, T., Kawamura, Y., Ono, Y., Sakota, E., Kotani, H., Asai, K., Siomi, H. & Siomi, M. C., 2009 10 29, : : Nature. 461, 7268, p. 1296-1299 4 p.

研究成果: Article

277 引用 (Scopus)

Armitage determines Piwi−piRISC processing from precursor formation and quality control to inter-organelle translocation

Yamashiro, H., Negishi, M., Kinoshita, T., Ishizu, H., Ohtani, H. & Siomi, M. C., 2020 2 5, : : EMBO Reports. 21, 2, e48769.

研究成果: Article

2 引用 (Scopus)

A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila

Gunawardane, L. S., Saito, K., Nishida, K. M., Miyoshi, K., Kawamura, Y., Nagami, T., Siomi, H. & Siomi, M. C., 2007 3 16, : : Science. 315, 5818, p. 1587-1590 4 p.

研究成果: Article

769 引用 (Scopus)

Astrocyte-specific expression of human T-cell lymphotropic virus type 1 (HTLV-1) Tax: Induction of tumor necrosis factor alpha and susceptibility to lysis by CD8+ HTLV-1-specific cytotoxic T cells

Méndez, E., Kawanishi, T., Clemens, K., Siomi, H., Soldan, S. S., Calabresi, P., Brady, J. & Jacobson, S., 1997 12, : : Journal of Virology. 71, 12, p. 9143-9149 7 p.

研究成果: Article

公開
26 引用 (Scopus)
4 引用 (Scopus)

Biogenesis pathways of piRNAs loaded onto AGO3 in the Drosophila testis

Nagao, A., Mituyama, T., Huang, H., Chen, D., Siomi, M. C. & Siomi, H., 2010 12, : : RNA. 16, 12, p. 2503-2515 13 p.

研究成果: Article

68 引用 (Scopus)

Broad cross-reactive epitopes of the H5N1 influenza virus identified by murine antibodies against the A/Vietnam/1194/2004 hemagglutinin

Kobayashi-Ishihara, M., Takahashi, H., Ohnishi, K., Nishimura, K., Terahara, K., Ato, M., Itamura, S., Kageyama, T. & Tsunetsugu-Yokota, Y., 2014 6 19, : : PloS one. 9, 6, e99201.

研究成果: Article

公開
2 引用 (Scopus)

Broad Heterochromatic Domains Open in Gonocyte Development Prior to De Novo DNA Methylation

Yamanaka, S., Nishihara, H., Toh, H., Eijy Nagai, L. A., Hashimoto, K., Park, S. J., Shibuya, A., Suzuki, A. M., Tanaka, Y., Nakai, K., Carninci, P., Sasaki, H. & Siomi, H., 2019 10 7, : : Developmental Cell. 51, 1, p. 21-34.e5

研究成果: Article

4 引用 (Scopus)

C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning

Guipponi, M., Brunschwig, K., Chamoun, Z., Scott, H. S., Shibuya, K., Kudoh, J., Delezoide, A. L., El Samadi, S., Chettouh, Z., Rossier, C., Shimizu, N., Mueller, F., Delabar, J. M. & Antonarakis, S. E., 2000 8 15, : : Genomics. 68, 1, p. 30-40 11 p.

研究成果: Article

15 引用 (Scopus)

Caffeic Acid Phenethyl Ester Induces Apoptosis by Inhibition of NFκB and Activation of Fas in Human Breast Cancer MCF-7 Cells

Watabe, M., Hishikawa, K., Takayanagi, A., Shimizu, N. & Nakaki, T., 2004 2 13, : : Journal of Biological Chemistry. 279, 7, p. 6017-6026 10 p.

研究成果: Article

179 引用 (Scopus)

Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties

Siomi, M. C., Higashijima, K., Ishizuka, A. & Siomi, H., 2002 12, : : Molecular and cellular biology. 22, 24, p. 8438-8447 10 p.

研究成果: Article

74 引用 (Scopus)

Characterization of Autoantibodies in Pemphigus Using Antigen-Specific Enzyme-Linked Immunosorbent Assays with Baculovirus-Expressed Recombinant Desmogleins

Ishii, K., Amagai, M., Hall, R. P., Hashimoto, T., Takayanagi, A., Gamou, S., Shimizu, N. & Nishikawa, T., 1997 8 15, : : Journal of Immunology. 159, 4, p. 2010-2017 8 p.

研究成果: Article

418 引用 (Scopus)

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing

Azuma-Mukai, A., Oguri, H., Mituyama, T., Zhi, R. Q., Asai, K., Siomi, H. & Siomi, M. C., 2008 6 10, : : Proceedings of the National Academy of Sciences of the United States of America. 105, 23, p. 7964-7969 6 p.

研究成果: Article

188 引用 (Scopus)

Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway

Miyoshi, K., Okada, T. N., Siomi, H. & Siomi, M. C., 2009 7, : : RNA. 15, 7, p. 1282-1291 10 p.

研究成果: Article

74 引用 (Scopus)

Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila

Cernilogar, F. M., Onorati, M. C., Kothe, G. O., Burroughs, A. M., Parsi, K. M., Breiling, A., Sardo, F. L., Saxena, A., Miyoshi, K., Siomi, H., Siomi, M. C., Carninci, P., Gilmour, D. S., Corona, D. F. V. & Orlando, V., 2011 12 15, : : Nature. 480, 7377, p. 391-395 5 p.

研究成果: Article

151 引用 (Scopus)

Cis/trans-activation of the interleukin-9 receptor gene in an HTLV-I-transformed human lymphocytic cell

Kubota, S., Siomi, H., Hatanaka, M. & Pomerantz, R. J., 1996, : : Oncogene. 12, 7, p. 1441-1447 7 p.

研究成果: Article

14 引用 (Scopus)

Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: Mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency

Bartoloni, L., Wattenhofer, M., Kudoh, J., Berry, A., Shibuya, K., Kawasaki, K., Wang, J., Asakawa, S., Talior, I., Bonne-Tamir, B., Rossier, C., Michaud, J., McCabe, E. R. B., Minoshima, S., Shimizu, N., Scott, H. S. & Antonarakis, S. E., 2000 12 1, : : Genomics. 70, 2, p. 190-200 11 p.

研究成果: Article

26 引用 (Scopus)

Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells

Machida, Y., Chiba, T., Takayanagi, A., Tanaka, Y., Asanuma, M., Ogawa, N., Koyama, A., Iwatsubo, T., Ito, S., Jansen, P. H., Shimizu, N., Tanaka, K., Mizuno, Y. & Hattori, N., 2005 6 24, : : Biochemical and Biophysical Research Communications. 332, 1, p. 233-240 8 p.

研究成果: Article

57 引用 (Scopus)

Comparative genomics of the keratin-associated protein (KAP) gene clusters in human, chimpanzee, and baboon

Shibuya, K., Kudoh, J., Obayashi, I., Shimizu, A., Sasaki, T., Minoshima, S. & Shimizu, N., 2004 3, : : Mammalian Genome. 15, 3, p. 179-192 14 p.

研究成果: Article

9 引用 (Scopus)

Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins

Kasashima, K., Sakashita, E., Saito, K. & Sakamoto, H., 2002 10 15, : : Nucleic acids research. 30, 20, p. 4519-4526 8 p.

研究成果: Article

公開
53 引用 (Scopus)

Constitutive activation of nuclear factor-κB prevents TRAIL-induced apoptosis in renal cancer cells

Oya, M., Ohtsubo, M., Takayanagi, A., Tachibana, M., Shimizu, N. & Murai, M., 2001 6 28, : : Oncogene. 20, 29, p. 3888-3896 9 p.

研究成果: Article

133 引用 (Scopus)

Construction and characterization of single-chain antibodies against human insulin-like growth factor-I receptor from hybridomas producing 1H7 or 3B7 monoclonal antibody

Kusada, Y., Morizono, T., Matsumoto-Takasaki, A., Sakai, K., Sato, S., Asanuma, H., Takayanagi, A. & Fujita-Yamaguchi, Y., 2008 1 1, : : Journal of biochemistry. 143, 1, p. 9-19 11 p.

研究成果: Article

7 引用 (Scopus)

Crystal structure and activity of the endoribonuclease domain of the piRNA pathway factor maelstrom

Matsumoto, N., Sato, K., Nishimasu, H., Namba, Y., Miyakubi, K., Dohmae, N., Ishitani, R., Siomi, H., Siomi, M. C. & Nureki, O., 2015 4 21, : : Cell Reports. 11, 3, p. 366-375 10 p.

研究成果: Article

19 引用 (Scopus)

Crystal structure of Drosophila Piwi

Yamaguchi, S., Oe, A., Nishida, K. M., Yamashita, K., Kajiya, A., Hirano, S., Matsumoto, N., Dohmae, N., Ishitani, R., Saito, K., Siomi, H., Nishimasu, H., Siomi, M. C. & Nureki, O., 2020 12 1, : : Nature communications. 11, 1, 858.

研究成果: Article

公開
1 引用 (Scopus)

Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA

Matsumoto, N., Nishimasu, H., Sakakibara, K., Nishida, K. M., Hirano, T., Ishitani, R., Siomi, H., Siomi, M. C. & Nureki, O., 2016 10 6, : : Cell. 167, 2, p. 484-497.e9

研究成果: Article

46 引用 (Scopus)

Deep sequencing and high-throughput analysis of PIWI-associated small RNAs

Iwasaki, Y., Ishino, K. & Siomi, H., 2017 3 28, (Accepted/In press) : : Methods.

研究成果: Article

3 引用 (Scopus)

Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16

Owczarek, C. M., Portbury, K. J., Hardy, M. P., O'Leary, D. A., Kudoh, J., Shibuya, K., Shimizu, N., Kola, I. & Hertzog, P. J., 2004 1 7, : : Gene. 324, 1-2, p. 65-77 13 p.

研究成果: Article

32 引用 (Scopus)

Development of a sensitive novel diagnostic kit for the highly pathogenic avian influenza A (H5N1) virus

Tsunetsugu-Yokota, Y., Nishimura, K., Misawa, S., Kobayashi-Ishihara, M., Takahashi, H., Takayama, I., Ohnishi, K., Itamura, S., Nguyen, H. L. K., Le, M. T. Q., Dang, G. T., Nguyen, L. T., Tashiro, M. & Kageyama, T., 2014 7 3, : : BMC infectious diseases. 14, 1, 362.

研究成果: Article

公開
6 引用 (Scopus)

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

Okamura, K., Ishizuka, A., Siomi, H. & Siomi, M. C., 2004 7 15, : : Genes and Development. 18, 14, p. 1655-1666 12 p.

研究成果: Article

587 引用 (Scopus)

DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary

Ohtani, H., Iwasaki, Y. W., Shibuya, A., Siomi, H., Siomi, M. C. & Saito, K., 2013 8 1, : : Genes and Development. 27, 15, p. 1656-1661 6 p.

研究成果: Article

71 引用 (Scopus)

Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

Kawamura, Y., Saito, K., Kin, T., Ono, Y., Asai, K., Sunohara, T., Okada, T. N., Siomi, M. C. & Siomi, H., 2008 6 5, : : Nature. 453, 7196, p. 793-797 5 p.

研究成果: Article

314 引用 (Scopus)

Drpiwi-1 is essential for germline cell formation during sexualization of the planarian Dugesia ryukyuensis

Nakagawa, H., Ishizu, H., Hasegawa, R., Kobayashi, K. & Matsumoto, M., 2012 1 1, : : Developmental Biology. 361, 1, p. 167-176 10 p.

研究成果: Article

19 引用 (Scopus)

Effects of neonatal diethylstilbestrol exposure on c-fos and c-jun protooncogene expression in the mouse uterus

Yamashita, S., Takayanagi, A. & Shimizu, N., 2001, : : Histology and Histopathology. 16, 1, p. 131-140 10 p.

研究成果: Article

19 引用 (Scopus)

Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences

Hartig, J. V., Esslinger, S., Böttcher, R., Saito, K. & Förstemann, K., 2009, : : EMBO Journal. 28, 19, p. 2932-2944 13 p.

研究成果: Article

69 引用 (Scopus)

Epigenetic Heterogeneity in HIV-1 Latency Establishment

Matsuda, Y., Kobayashi-Ishihara, M., Fujikawa, D., Ishida, T., Watanabe, T. & Yamagishi, M., 2015 1 9, : : Scientific reports. 5, 7701.

研究成果: Article

公開
36 引用 (Scopus)

Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection

Kiga, K., Mimuro, H., Suzuki, M., Shinozaki-Ushiku, A., Kobayashi, T., Sanada, T., Kim, M., Ogawa, M., Iwasaki, Y. W., Kayo, H., Fukuda-Yuzawa, Y., Yashiro, M., Fukayama, M., Fukao, T. & Sasakawa, C., 2014, : : Nature communications. 5, 4497.

研究成果: Article

78 引用 (Scopus)

Epithelial overexpression of interleukin-32α in inflammatory bowel disease

Shioya, M., Nishida, A., Yagi, Y., Ogawa, A., Tsujikawa, T., Kim-Mitsuyama, S., Takayanagi, A., Shimizu, N., Fujiyama, Y. & Andoh, A., 2007 9, : : Clinical and Experimental Immunology. 149, 3, p. 480-486 7 p.

研究成果: Article

159 引用 (Scopus)

Essential roles of Windei and nuclear monoubiquitination of Eggless/SETDB1 in transposon silencing

Osumi, K., Sato, K., Murano, K., Siomi, H. & Siomi, M. C., 2019 1 1, (Accepted/In press) : : EMBO Reports. e48296.

研究成果: Article

4 引用 (Scopus)

Evolutionary dynamics of the human immunoglobulin κ locus and the germline repertoire of the Vκ genes

Kawasaki, K., Minoshima, S., Nakato, E., Shibuya, K., Shintani, A., Asakawa, S., Sasaki, T., Klobeck, H. G., Combriato, G., Zachau, H. G. & Shimizu, N., 2001, : : European Journal of Immunology. 31, 4, p. 1017-1028 12 p.

研究成果: Article

42 引用 (Scopus)

Expression of c-fos and c-jun protooncogenes in the uteri of immature mice neonatally exposed to diethylstilbestrol

Yamashita, S., Takayanagi, A. & Shimizu, N., 2003 1, : : Histology and Histopathology. 18, 1, p. 83-92 10 p.

研究成果: Article

3 引用 (Scopus)