研究成果

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Article
2012

RNA elimination machinery targeting meiotic mRNAs promotes facultative heterochromatin formation

Zofall, M., Yamanaka, S., Reyes-Turcu, F. E., Zhang, K., Rubin, C. & Grewal, S. I. S., 2012 1 6, : : Science. 335, 6064, p. 96-100 5 p.

研究成果: Article

112 引用 (Scopus)

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

Nishimasu, H., Ishizu, H., Saito, K., Fukuhara, S., Kamatani, M. K., Bonnefond, L., Matsumoto, N., Nishizawa, T., Nakanaga, K., Aoki, J., Ishitani, R., Siomi, H., Siomi, M. C. & Nureki, O., 2012 11 8, : : Nature. 491, 7423, p. 284-287 4 p.

研究成果: Article

180 引用 (Scopus)
14 引用 (Scopus)
2011
4 引用 (Scopus)

Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila

Cernilogar, F. M., Onorati, M. C., Kothe, G. O., Burroughs, A. M., Parsi, K. M., Breiling, A., Sardo, F. L., Saxena, A., Miyoshi, K., Siomi, H., Siomi, M. C., Carninci, P., Gilmour, D. S., Corona, D. F. V. & Orlando, V., 2011 12 15, : : Nature. 480, 7377, p. 391-395 5 p.

研究成果: Article

151 引用 (Scopus)

Gender-specific hierarchy in nuage localization of PIWI-interacting RNA factors in Drosophila

Nagao, A., Sato, K., Nishida, K. M., Siomi, H. & Siomi, M. C., 2011 12 1, : : Frontiers in Genetics. 2, AUG, Article 55.

研究成果: Article

18 引用 (Scopus)

Maelstrom coordinates microtubule organization during Drosophila oogenesis through interaction with components of the MTOC

Sato, K., Nishida, K. M., Shibuya, A., Siomi, M. C. & Siomi, H., 2011 11 15, : : Genes and Development. 25, 22, p. 2361-2373 13 p.

研究成果: Article

36 引用 (Scopus)

Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B

Fujiwara, Y., Kasashima, K., Saito, K., Fukuda, M., Fukao, A., Sasano, Y., Inoue, K., Fujiwara, T. & Sakamoto, H., 2011 5 1, : : Biochimie. 93, 5, p. 817-822 6 p.

研究成果: Article

13 引用 (Scopus)

Screening of scFv-displaying phages recognizing distinct extracellular domains of EGF receptor by target-guided proximity labeling method

Chang, C., Takayanagi, A., Yoshida, T. & Shimizu, N., 2011 9 30, : : Journal of Immunological Methods. 372, 1-2, p. 127-136 10 p.

研究成果: Article

5 引用 (Scopus)
2010

A direct role for Hsp90 in pre-RISC formation in Drosophila

Miyoshi, T., Takeuchi, A., Siomi, H. & Siomi, M. C., 2010 8, : : Nature Structural and Molecular Biology. 17, 8, p. 1024-1026 3 p.

研究成果: Article

104 引用 (Scopus)

Biogenesis pathways of piRNAs loaded onto AGO3 in the Drosophila testis

Nagao, A., Mituyama, T., Huang, H., Chen, D., Siomi, M. C. & Siomi, H., 2010 12, : : RNA. 16, 12, p. 2503-2515 13 p.

研究成果: Article

68 引用 (Scopus)

Fragile X carrier screening and FMR1 allele distribution in the Japanese population

Otsuka, S., Sakamoto, Y., Siomi, H., Itakura, M., Yamamoto, K., Matumoto, H., Sasaki, T., Kato, N. & Nanba, E., 2010 2 1, : : Brain and Development. 32, 2, p. 110-114 5 p.

研究成果: Article

38 引用 (Scopus)

Importance of polyadenylation in the selective elimination of meiotic mRNAs in growing S. pombe cells

Yamanaka, S., Yamashita, A., Harigaya, Y., Iwata, R. & Yamamoto, M., 2010 7 7, : : EMBO Journal. 29, 13, p. 2173-2181 9 p.

研究成果: Article

87 引用 (Scopus)

Is canalization more than just a beautiful idea?

Sato, K. & Siomi, H., 2010 3 16, : : Genome biology. 11, 3, 109.

研究成果: Article

9 引用 (Scopus)

Isolation and characterization of antibodies against three consecutive Tn-antigen clusters from a phage library displaying human single-chain variable fragments

Sakai, K., Yuasa, N., Tsukamoto, K., Takasaki-Matsumoto, A., Yajima, Y., Sato, R., Kawakami, H., Mizuno, M., Takayanagi, A., Shimizu, N., Nakata, M. & Fujita-Yamaguchi, Y., 2010 6 1, : : Journal of biochemistry. 147, 6, p. 809-817 9 p.

研究成果: Article

25 引用 (Scopus)

Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila

Miyoshi, K., Miyoshi, T., Hartig, J. V., Siomi, H. & Siomi, M. C., 2010 3, : : RNA. 16, 3, p. 506-515 10 p.

研究成果: Article

61 引用 (Scopus)

Natural Variation of the Amino-Terminal Glutamine-Rich Domain in Drosophila Argonaute2 Is Not Associated with Developmental Defects

Hain, D., Bettencourt, B. R., Okamura, K., Csorba, T., Meyer, W., Jin, Z., Biggerstaff, J., Siomi, H., Hutvagner, G., Lai, E. C., Welte, M. & Müller, H. A. J., 2010, : : PloS one. 5, 12, p. 1-14 14 p., e15264.

研究成果: Article

25 引用 (Scopus)

Regulation of Nucleolar Chromatin by B23/Nucleophosmin Jointly Depends upon Its RNA Binding Activity and Transcription Factor UBF

Hisaoka, M., Ueshima, S., Murano, K., Nagata, K. & Okuwaki, M., 2010 10, : : Molecular and cellular biology. 30, 20, p. 4952-4964 13 p.

研究成果: Article

26 引用 (Scopus)

Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila

Saito, K., Ishizu, H., Komai, M., Kotani, H., Kawamura, Y., Nishida, K. M., Siomi, H. & Siomi, M. C., 2010 11 15, : : Genes and Development. 24, 22, p. 2493-2498 6 p.

研究成果: Article

204 引用 (Scopus)

Simple PCR-based DNA microarray system to identify human pathogenic fungi in skin

Sato, T., Takayanagi, A., Nagao, K., Tomatsu, N., Fukui, T., Kawaguchi, M., Kudoh, J., Amagai, M., Yamamoto, N. & Shimizu, N., 2010 7, : : Journal of Clinical Microbiology. 48, 7, p. 2357-2364 8 p.

研究成果: Article

32 引用 (Scopus)
2009

A microRNA regulatory mechanism of osteoblast differentiation

Inose, H., Ochi, H., Kimura, A., Fujita, K., Xu, R., Sato, S., Iwasaki, M., Sunamura, S., Takeuchi, Y., Fukumoto, S., Saito, K., Nakamura, T., Siomi, H., Ito, H., Arai, Y., Shinomiya, K. I. & Takeda, S., 2009 12 8, : : Proceedings of the National Academy of Sciences of the United States of America. 106, 49, p. 20794-20799 6 p.

研究成果: Article

210 引用 (Scopus)

A regulatory circuit for piwi by the large Maf gene traffic jam in Drosophila

Saito, K., Inagaki, S., Mituyama, T., Kawamura, Y., Ono, Y., Sakota, E., Kotani, H., Asai, K., Siomi, H. & Siomi, M. C., 2009 10 29, : : Nature. 461, 7268, p. 1296-1299 4 p.

研究成果: Article

277 引用 (Scopus)

Characterization of the miRNA-RISC loading complex and miRNA-RISC formed in the Drosophila miRNA pathway

Miyoshi, K., Okada, T. N., Siomi, H. & Siomi, M. C., 2009 7, : : RNA. 15, 7, p. 1282-1291 10 p.

研究成果: Article

74 引用 (Scopus)

Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences

Hartig, J. V., Esslinger, S., Böttcher, R., Saito, K. & Förstemann, K., 2009, : : EMBO Journal. 28, 19, p. 2932-2944 13 p.

研究成果: Article

69 引用 (Scopus)

Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines

Nishida, K. M., Okada, T. N., Kawamura, T., Mituyama, T., Kawamura, Y., Inagaki, S., Huang, H., Chen, D., Kodama, T., Siomi, H. & Siomi, M. C., 2009 12, : : EMBO Journal. 28, 24, p. 3820-3831 12 p.

研究成果: Article

129 引用 (Scopus)

Isolation and characterization of anti-T-antigen single chain antibodies from a phage library

Matsumoto-Takasaki, A., Horie, J., Sakai, K., Furui, Y., Sato, R., Kawakami, H., Toma, K., Takayanagi, A., Shimizu, N. & Fujita-Yamaguchi, Y., 2009 12 1, : : BioScience Trends. 3, 3, p. 87-95 9 p.

研究成果: Article

11 引用 (Scopus)

RISC hitches onto endosome trafficking

Siomi, H. & Siomi, M. C., 2009 9 14, : : Nature Cell Biology. 11, 9, p. 1049-1051 3 p.

研究成果: Article

32 引用 (Scopus)
2008

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing

Azuma-Mukai, A., Oguri, H., Mituyama, T., Zhi, R. Q., Asai, K., Siomi, H. & Siomi, M. C., 2008 6 10, : : Proceedings of the National Academy of Sciences of the United States of America. 105, 23, p. 7964-7969 6 p.

研究成果: Article

188 引用 (Scopus)

Construction and characterization of single-chain antibodies against human insulin-like growth factor-I receptor from hybridomas producing 1H7 or 3B7 monoclonal antibody

Kusada, Y., Morizono, T., Matsumoto-Takasaki, A., Sakai, K., Sato, S., Asanuma, H., Takayanagi, A. & Fujita-Yamaguchi, Y., 2008 1 1, : : Journal of biochemistry. 143, 1, p. 9-19 11 p.

研究成果: Article

7 引用 (Scopus)

Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

Kawamura, Y., Saito, K., Kin, T., Ono, Y., Asai, K., Sunohara, T., Okada, T. N., Siomi, M. C. & Siomi, H., 2008 6 5, : : Nature. 453, 7196, p. 793-797 5 p.

研究成果: Article

314 引用 (Scopus)

Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-32α induction in human pancreatic periacinar myofibroblasts

Nishida, A., Andoh, A., Shioya, M., Kim-Mitsuyama, S., Takayanagi, A. & Fujiyama, Y., 2008 3 1, : : American Journal of Physiology - Gastrointestinal and Liver Physiology. 294, 3, p. G831-G838

研究成果: Article

30 引用 (Scopus)

Production of diploid and triploid offspring by inbreeding of the triploid planarian Dugesia ryukyuensis

Kobayashi, K., Ishizu, H., Arioka, S., Cabrera, J. P., Hoshi, M. & Matsumoto, M., 2008 6 1, : : Chromosoma. 117, 3, p. 289-296 8 p.

研究成果: Article

6 引用 (Scopus)
101 引用 (Scopus)
2007

A Bioartificial Liver Device Secreting Interleukin-1 Receptor Antagonist for the Treatment of Hepatic Failure in Rats

Shinoda, M., Tilles, A. W., Kobayashi, N., Wakabayashi, G., Takayanagi, A., Totsugawa, T., Harada, H., Obara, H., Suganuma, K., Berthiaume, F., Shimazu, M., Shimizu, N., Tanaka, N., Kitajima, M., Tompkins, R. G., Toner, M. & Yarmush, M. L., 2007 1, : : Journal of Surgical Research. 137, 1, p. 130-140 11 p.

研究成果: Article

20 引用 (Scopus)

A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila

Gunawardane, L. S., Saito, K., Nishida, K. M., Miyoshi, K., Kawamura, Y., Nagami, T., Siomi, H. & Siomi, M. C., 2007 3 16, : : Science. 315, 5818, p. 1587-1590 4 p.

研究成果: Article

769 引用 (Scopus)

Epithelial overexpression of interleukin-32α in inflammatory bowel disease

Shioya, M., Nishida, A., Yagi, Y., Ogawa, A., Tsujikawa, T., Kim-Mitsuyama, S., Takayanagi, A., Shimizu, N., Fujiyama, Y. & Andoh, A., 2007 9, : : Clinical and Experimental Immunology. 149, 3, p. 480-486 7 p.

研究成果: Article

159 引用 (Scopus)

Gene silencing mechanisms mediated by Aubergine-piRNA complexes in Drosophila male gonad

Nishida, K. M., Saito, K., Mori, T., Kawamura, Y., Nagami-Okada, T., Inagaki, S., Siomi, H. & Siomi, M. C., 2007 11, : : RNA. 13, 11, p. 1911-1922 12 p.

研究成果: Article

167 引用 (Scopus)

Isolation and characterization of phage-displayed single chain antibodies recognizing nonreducing terminal mannose residues. 1. A new strategy for generation of anti-carbohydrate antibodies

Sakai, K., Shimizu, Y., Chiba, T., Matsumoto-Takasaki, A., Kusada, Y., Zhang, W., Nakata, M., Kojima, N., Toma, K., Takayanagi, A., Shimizu, N. & Fujita-Yamaguchi, Y., 2007 1 9, : : Biochemistry. 46, 1, p. 253-262 10 p.

研究成果: Article

22 引用 (Scopus)

Matrix metalloproteinase-3 secretion from human pancreatic periacinar myofibroblasts in response to inflammatory mediators

Inatomi, O., Andoh, A., Yagi, Y., Ogawa, A., Hata, K., Shiomi, H., Tani, T., Takayanagi, A., Shimizu, N. & Fujiyama, Y., 2007 1, : : Pancreas. 34, 1, p. 126-132 7 p.

研究成果: Article

14 引用 (Scopus)

Novel RNA silencing pathway triggered by Piwi and rasiRNA

Saito, K. & Mikiko, C. S., 2007 3 1, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 52, 3, p. 221-226 6 p.

研究成果: Article

Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination

Lim, M. K., Kawamura, T., Ohsawa, Y., Ohtsubo, M., Asakawa, S., Takayanagi, A. & Shimizu, N., 2007 8 1, : : Experimental Cell Research. 313, 13, p. 2858-2874 17 p.

研究成果: Article

52 引用 (Scopus)

Pimet, the Drosophila homolog of HEN1, mediates 2′-O-methylation of Piwi-interacting RNAs at their 3′ ends

Saito, K., Sakaguchi, Y., Suzuki, T., Suzuki, T., Siomi, H. & Siomi, M. C., 2007 7 1, : : Genes and Development. 21, 13, p. 1603-1608 6 p.

研究成果: Article

291 引用 (Scopus)
2006

Selective elimination of messenger RNA prevents an incidence of untimely meiosis

Harigaya, Y., Tanaka, H., Yamanaka, S., Tanaka, K., Watanabe, Y., Tsutsumi, C., Chikashige, Y., Hiraoka, Y., Yamashita, A. & Yamamoto, M., 2006 7 6, : : Nature. 442, 7098, p. 45-50 6 p.

研究成果: Article

210 引用 (Scopus)

Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome

Saito, K., Nishida, K. M., Mori, T., Kawamura, Y., Miyoshi, K., Nagami, T., Siomi, H. & Siomi, M. C., 2006 8 15, : : Genes and Development. 20, 16, p. 2214-2222 9 p.

研究成果: Article

432 引用 (Scopus)

Treatment of fulminant hepatic failure in rats using a bioartificial liver device containing porcine hepatocytes producing interleukin-1 receptor antagonist

Shinoda, M., Tilles, A. W., Wakabayashi, G., Takayanagi, A., Harada, H., Obara, H., Suganuma, K., Berthiaume, F., Shimazu, M., Shimizu, N., Kitajima, M., Tompkins, R. G., Toner, M. & Yarmush, M. L., 2006 5, : : Tissue Engineering. 12, 5, p. 1313-1323 11 p.

研究成果: Article

16 引用 (Scopus)
2005

A potential link between transgene silencing and poly(A) tails

Siomi, M. C., Tsukumo, H., Ishizuka, A., Nagami, T. & Siomi, H., 2005 7, : : RNA. 11, 7, p. 1004-1011 8 p.

研究成果: Article

13 引用 (Scopus)

Common anti-apoptotic roles of parkin and α-synuclein in human dopaminergic cells

Machida, Y., Chiba, T., Takayanagi, A., Tanaka, Y., Asanuma, M., Ogawa, N., Koyama, A., Iwatsubo, T., Ito, S., Jansen, P. H., Shimizu, N., Tanaka, K., Mizuno, Y. & Hattori, N., 2005 6 24, : : Biochemical and Biophysical Research Communications. 332, 1, p. 233-240 8 p.

研究成果: Article

57 引用 (Scopus)
5 引用 (Scopus)

Interleukin-17 and lipopolysaccharides synergistically induce cyclooxygenase-2 expression in human intestinal myofibroblasts

Zhang, Z., Andoh, A., Inatomi, O., Bamba, S., Takayanagi, A., Shimizu, N. & Fujiyama, Y., 2005 4, : : Journal of Gastroenterology and Hepatology (Australia). 20, 4, p. 619-627 9 p.

研究成果: Article

27 引用 (Scopus)

Interleukin-17 augments tumor necrosis factor-α-induced granulocyte and granulocyte/macrophage colony-stimulating factor release from human colonic myofibroblasts

Andoh, A., Yasui, H., Inatomi, O., Zhang, Z., Deguchi, Y., Hata, K., Araki, Y., Tsujikawa, T., Kitoh, K., Kim-Mitsuyama, S., Takayanagi, A., Shimizu, N. & Fujiyama, Y., 2005 8, : : Journal of gastroenterology. 40, 8, p. 802-810 9 p.

研究成果: Article

31 引用 (Scopus)