研究成果 1988 2017

フィルター
Article
2017
1 引用 (Scopus)

Identification of dietary patterns and their relationships with general and oral health in the very old

Osawa, Y., Arai, Y., Takayama, M., Hirata, T., Kawasaki, M., Abe, Y., Iinuma, T., Sasaki, S. & Hirose, N., 2017, : : Asia Pacific Journal of Clinical Nutrition. 26, 2, p. 262-270 9 p.

研究成果: Article

Bite Force
Oral Health
Dentures
Health Status
Population
1 引用 (Scopus)

Perceived swallowing problems and mortality risk in very elderly people ≥85 years old: Results of the Tokyo Oldest Old Survey on Total Health study

Iinuma, T., Hirata, T., Arai, Y., Takayama, M., Abe, Y., Fukumoto, M., Fukui, Y. & Gionhaku, N., 2017, (Accepted/In press) : : Gerodontology.

研究成果: Article

Tokyo
Deglutition
Mortality
Health
Oral Health
4 引用 (Scopus)

Relationships of muscle echo intensity with walking ability and physical activity in the very old population

Osawa, Y., Arai, Y., Oguma, Y., Hirata, T., Abe, Y., Azuma, K., Takayama, M. & Hirose, N., 2017 4 1, : : Journal of Aging and Physical Activity. 25, 2, p. 189-195 7 p.

研究成果: Article

Walking
Muscles
Population
Patella
Thigh
3 引用 (Scopus)
Independent Living
Tokyo
Japan
Exercise
Surveys and Questionnaires
2016
4 引用 (Scopus)

Association between maximum occlusal force and 3-year all-cause mortality in community-dwelling elderly people

Iinuma, T., Arai, Y., Takayama, M., Abe, Y., Ito, T., Kondo, Y., Hirose, N. & Gionhaku, N., 2016 9 1, : : BMC Oral Health. 16, 1, 82.

研究成果: Article

Bite Force
Independent Living
Mortality
Proportional Hazards Models
Oral Health
5 引用 (Scopus)
Carotid Artery Diseases
Cytomegalovirus Infections
Cytomegalovirus
Cognition
Carotid Stenosis
8 引用 (Scopus)

Effects of the APOE ε4 allele and education on cognitive function in Japanese centenarians

Ishioka, Y. L., Gondo, Y., Fuku, N., Inagaki, H., Masui, Y., Takayama, M., Abe, Y., Arai, Y. & Hirose, N., 2016 8 24, (Accepted/In press) : : Age. p. 1-9 9 p.

研究成果: Article

Apolipoprotein E4
Cognition
Alleles
Education
Young Adult
4 引用 (Scopus)

Muscle-related polymorphisms (mstn rs1805086 and actn3 rs1815739) are not associated with exceptional longevity in Japanese centenarians

Fuku, N., Alis, R., Yvert, T., Zempo, H., Naito, H., Abe, Y., Arai, Y., Murakami, H., Miyachi, M., Pareja-Galeano, H., Emanuele, E., Hirose, N. & Lucia, A., 2016 11 1, : : PLoS One. 11, 11, e0166605.

研究成果: Article

Actinin
Polymorphism
Myostatin
Muscle
Genes
2 引用 (Scopus)

rs2802292 polymorphism in the FOXO3A gene and exceptional longevity in two ethnically distinct cohorts

Fuku, N., Díaz-Peña, R., Arai, Y., Abe, Y., Pareja-Galeano, H., Sanchis-Gomar, F., Santos-Lozano, A., Zempo, H., Naito, H., Murakami, H., Miyachi, M., Venturini, L., Ricevuti, G., Nobuyoshi, H., Emanuele, E. & Lucia, A., 2016 10 1, : : Maturitas. 92, p. 110-114 5 p.

研究成果: Article

Polymorphism
Genes
Italy
Young Adult
Outcome Assessment (Health Care)
2015
2 引用 (Scopus)

An unusual autopsy case of lethal hypothermia exacerbated by body lice-induced severe anemia

Nara, A., Nagai, H., Yamaguchi, R., Makino, Y., Chiba, F., Yoshida, K. I., Yajima, D. & Iwase, H., 2015 9 18, (Accepted/In press) : : International Journal of Legal Medicine.

研究成果: Article

Pediculus
Hypothermia
Anemia
Autopsy
Anoplura
13 引用 (Scopus)

Change in N-glycosylation of plasma proteins in Japanese semisupercentenarians

Miura, Y., Hashii, N., Tsumoto, H., Takakura, D., Ohta, Y., Abe, Y., Arai, Y., Kawasaki, N., Hirose, N. & Endo, T., 2015 11 1, : : PLoS One. 10, 11, e0142645.

研究成果: Article

Glycosylation
glycosylation
blood proteins
Polysaccharides
Blood Proteins
52 引用 (Scopus)

Denture wearing during sleep doubles the risk of pneumonia in the very elderly

Iinuma, T., Arai, Y., Abe, Y., Takayama, M., Fukumoto, M., Fukui, Y., Iwase, T., Takebayashi, T., Hirose, N., Gionhaku, N. & Komiyama, K., 2015 3 25, : : Journal of Dental Research. 94, p. 28S-36S

研究成果: Article

Dentures
Pneumonia
Sleep
Oral Health
Confidence Intervals
6 引用 (Scopus)

Exceptional longevity and muscle and fitness related genotypes: A functional in vitro analysis and case-control association replication study with SNPs THRH rs7832552, IL6 rs1800795 and ACSL1 rs6552828

Fuku, N., He, Z. H., Sanchis-Gomar, F., Pareja-Galeano, H., Tian, Y., Arai, Y., Abe, Y., Murakami, H., Miyachi, M., Zempo, H., Naito, H., Yvert, T., Verde, Z., Venturini, L., Fiuza-Luces, C., Santos-Lozano, A., Rodríguez, G., Ricevuti, G., Hirose, N., Emanuele, E. および2人, Garatachea, N. & Lucia, A., 2015, : : Frontiers in Aging Neuroscience. 7, APR, 59.

研究成果: Article

Single Nucleotide Polymorphism
Interleukin-6
Genotype
Muscles
Alleles
5 引用 (Scopus)

Identification of a jawless skull by superimposing post-mortem and ante-mortem CT

Iino, M., Fujimoto, H., Yoshida, M., Matsumoto, H. & Fujita, M. Q., 2015 6 9, (Accepted/In press) : : Journal of Forensic Radiology and Imaging.

研究成果: Article

Skull
Tomography
Jaw
Dental Records
Anthropology
87 引用 (Scopus)

Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians

Arai, Y., Martin-Ruiz, C. M., Takayama, M., Abe, Y., Takebayashi, T., Koyasu, S., Suematsu, M., Hirose, N. & von Zglinicki, T., 2015 10 1, : : EBioMedicine. 2, 10, p. 1549-1558 10 p.

研究成果: Article

Telomere
Longitudinal Studies
Aging of materials
Inflammation
Hazards
29 引用 (Scopus)

Influenza induces IL-8 and GM-CSF secretion by human alveolar epithelial cells through HGF/c-Met and TGF-α/EGFR signaling

Ito, Y., Correll, K., Zemans, R. L., Leslie, C. C., Murphy, R. C. & Mason, R. J., 2015 6 1, : : American Journal of Physiology - Lung Cellular and Molecular Physiology. 308, 11, p. L1178-L1188

研究成果: Article

Alveolar Epithelial Cells
Hepatocyte Growth Factor
Transforming Growth Factors
Granulocyte-Macrophage Colony-Stimulating Factor
Interleukin-8
2014
1 引用 (Scopus)

A case of an infant suffered from a fatal scald injury - Validity and limitations of postmortem CT imaging

Iino, M., Nakajima, Y., Ueno, M., Mikami, K. & Fujita, M. Q., 2014 11 1, : : Legal Medicine. 16, 6, p. 367-372 6 p.

研究成果: Article

Accidents
Tomography
Autopsy
Wounds and Injuries
Confidentiality
40 引用 (Scopus)

ApoE gene and exceptional longevity: Insights from three independent cohorts

Garatachea, N., Emanuele, E., Calero, M., Fuku, N., Arai, Y., Abe, Y., Murakami, H., Miyachi, M., Yvert, T., Verde, Z., Zea, M. A., Venturini, L., Santiago, C., Santos-Lozano, A., Rodríguez-Romo, G., Ricevuti, G., Hirose, N., Rábano, A. & Lucia, A., 2014, : : Experimental Gerontology. 53, p. 16-23 8 p.

研究成果: Article

Apolipoproteins E
Genes
Confidence Intervals
Alleles
Odds Ratio
20 引用 (Scopus)

Apolipoprotein B-48: A unique marker of chylomicron metabolism

Nakajima, K., Nagamine, T., Fujita, M. Q., Ai, M., Tanaka, A. & Schaefer, E., 2014, : : Advances in Clinical Chemistry. 64, p. 117-177 61 p.

研究成果: Article

Apolipoprotein B-48
Chylomicrons
Metabolism
Apolipoprotein B-100
Chylomicron Remnants
5 引用 (Scopus)

Attenuation of lung ischemia-reperfusion injury by Rho-associated kinase inhibition in a rat model of lung transplantation

Kohno, M., Watanabe, M., Goto, T., Kamiyama, I., Ohtsuka, T., Tasaka, S. & Sawafuji, M., 2014, : : Annals of Thoracic and Cardiovascular Surgery. 20, 5, p. 359-364 6 p.

研究成果: Article

rho-Associated Kinases
Lung Transplantation
Reperfusion Injury
Lung
Protein Kinases
22 引用 (Scopus)
Alveolar Epithelial Cells
Hepatocyte Growth Factor
Acute Lung Injury
Adult Respiratory Distress Syndrome
Fibroblasts
22 引用 (Scopus)
Japan
Mortality
Survival
Activities of Daily Living
Telephone
5 引用 (Scopus)

PTK2 rs7460 and rs7843014 polymorphisms and exceptional longevity: A functional replication study

Garatachea, N., Fuku, N., He, Z. H., Tian, Y., Arai, Y., Abe, Y., Murakami, H., Miyachi, M., Yvert, T., Venturini, L., Santiago, C., Santos-Lozano, A., Rodríguez, G., Ricevuti, G., Pareja-Galeano, H., Sanchis-Gomar, F., Emanuele, E., Hirose, N. & Lucia, A., 2014 10 1, : : Rejuvenation Research. 17, 5, p. 430-438 9 p.

研究成果: Article

Alleles
Single Nucleotide Polymorphism
Odds Ratio
Genotype
Confidence Intervals
5 引用 (Scopus)

Spleen stiffness measurements by acoustic radiation force impulse imaging after living donor liver transplantation in children: a potential quantitative index for venous complications

Tomita, H., Fuchimoto, Y., Ohkuma, K., Hoshino, K., Fujino, A., Kato, M., Fujimura, T., Ishihama, H., Takahashi, N., Tanami, Y., Nakatsuka, S., Ebinuma, H., Saito, H., Shinoda, M., Kitagawa, Y. & Kuroda, T., 2014 12 12, (Accepted/In press) : : Pediatric Radiology.

研究成果: Article

Elasticity Imaging Techniques
Living Donors
Liver Transplantation
Spleen
Pathologic Constriction
11 引用 (Scopus)

Stanniocalcin-1 is induced by hypoxia inducible factor in rat alveolar epithelial cells

Ito, Y., Zemans, R., Correll, K., Yang, I. V., Ahmad, A., Gao, B. & Mason, R. J., 2014 10 3, : : Biochemical and Biophysical Research Communications. 452, 4, p. 1091-1097 7 p.

研究成果: Article

Alveolar Epithelial Cells
Rats
Gene expression
Genes
Gene Expression
6 引用 (Scopus)

The rs1333049 polymorphism on locus 9p21.3 and extreme longevity in Spanish and Japanese cohorts

Pinós, T., Fuku, N., Cámara, Y., Arai, Y., Abe, Y., Rodríguez-Romo, G., Garatachea, N., Santos-Lozano, A., Miro-Casas, E., Ruiz-Meana, M., Otaegui, I., Murakami, H., Miyachi, M., Garcia-Dorado, D., Hinohara, K., Andreu, A. L., Kimura, A., Hirose, N. & Lucia, A., 2014, : : Age. 36, 2, p. 933-943 11 p.

研究成果: Article

Coronary Artery Disease
Genotype
Alleles
Rejuvenation
Gene Frequency
2013
19 引用 (Scopus)
Independent Living
Eicosapentaenoic Acid
Docosahexaenoic Acids
Omega-3 Fatty Acids
Erythrocyte Membrane
16 引用 (Scopus)

Innate immune response of human alveolar type II cells infected with severe acute respiratory syndrome-coronavirus

Qian, Z., Travanty, E. A., Oko, L., Edeen, K., Berglund, A., Wang, J., Ito, Y., Holmes, K. V. & Mason, R. J., 2013 6, : : American Journal of Respiratory Cell and Molecular Biology. 48, 6, p. 742-748 7 p.

研究成果: Article

Alveolar Epithelial Cells
Severe Acute Respiratory Syndrome
Coronavirus
Innate Immunity
Interferons
2012
41 引用 (Scopus)

IL-10 regulates Il12b expression via histone deacetylation: Implications for intestinal macrophage homeostasis

Kobayashi, T., Matsuoka, K., Sheikh, S. Z., Russo, S. M., Mishima, Y., Collins, C., DeZoeten, E. F., Karp, C. L., Ting, J. P. Y., Sartor, R. B. & Plevy, S. E., 2012 8 15, : : Journal of Immunology. 189, 4, p. 1792-1799 8 p.

研究成果: Article

Interleukin-10
Histones
Homeostasis
Macrophages
Specific Pathogen-Free Organisms
19 引用 (Scopus)

Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells

Nishida, A., Nagahama, K., Imaeda, H., Ogawa, A., Lau, C. W., Kobayashi, T., Hisamatsu, T., Preffer, F. I., Mizoguchi, E., Ikeuchi, H., Hibi, T., Fukuda, M., Andoh, A., Blumberg, R. S. & Mizoguchi, A., 2012 12 17, : : Journal of Experimental Medicine. 209, 13, p. 2383-2394 12 p.

研究成果: Article

Colitis
T-Lymphocytes
Polysaccharides
Galectin 4
Immunological Synapses
55 引用 (Scopus)

Innate immune response of human alveolar macrophages during influenza a infection

Wang, J., Nikrad, M. P., Travanty, E. A., Zhou, B., Phang, T., Gao, B., Alford, T., Ito, Y., Nahreini, P., Hartshorn, K., Wentworth, D., Dinarello, C. A. & Mason, R. J., 2012 3 2, : : PLoS One. 7, 3, e29879.

研究成果: Article

Alveolar Macrophages
Viruses
Innate Immunity
influenza
Human Influenza
2 引用 (Scopus)

Tuberous sclerosis diagnosed by incidental computed tomography findings of multifocal micronodular pneumocyte hyperplasia: A case report

Ishii, M., Asano, K., Kamiishi, N., Hayashi, Y., Arai, D., Haraguchi, M., Sugiura, H., Naoki, K., Tasaka, S., Soejima, K., Sayama, K. & Betsuyaku, T., 2012, : : Journal of Medical Case Reports. 6, 352.

研究成果: Article

Alveolar Epithelial Cells
Tuberous Sclerosis
Hyperplasia
Tomography
Glass
2011
56 引用 (Scopus)

Adipokines and aging

Arai, Y., Takayama, M., Abe, Y. & Hirose, N., 2011, : : Journal of Atherosclerosis and Thrombosis. 18, 7, p. 545-550 6 p.

研究成果: Article

Adipokines
Adipose Tissue
Aging of materials
Tissue
Insulin Resistance
87 引用 (Scopus)

An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis

Sheikh, S. Z., Hegazi, R. A., Kobayashi, T., Onyiah, J. C., Russo, S. M., Matsuoka, K., Sepulveda, A. R., Li, F., Otterbein, L. E. & Plevy, S. E., 2011 5 1, : : Journal of Immunology. 186, 9, p. 5506-5513 8 p.

研究成果: Article

Heme Oxygenase-1
Colitis
Carbon Monoxide
Anti-Inflammatory Agents
Interleukin-10
11 引用 (Scopus)

Human C-reactive protein exacerbates metabolic disorders in association with adipose tissue remodelling

Kaneko, H., Anzai, T., Nagai, T., Anzai, A., Takahashi, T., Mano, Y., Morimoto, K., Maekawa, Y., Itoh, H., Yoshikawa, T., Ogawa, S. & Fukuda, K., 2011 8 1, : : Cardiovascular Research. 91, 3, p. 546-555 10 p.

研究成果: Article

High Fat Diet
C-Reactive Protein
Adipose Tissue
Transgenic Mice
Adiponectin
20 引用 (Scopus)

Hypoxia-inducible factor regulates expression of surfactant protein in alveolar type II cells in vitro

Ito, Y., Ahmad, A., Kewley, E. & Mason, R. J., 2011 11 1, : : American Journal of Respiratory Cell and Molecular Biology. 45, 5, p. 938-945 8 p.

研究成果: Article

Alveolar Epithelial Cells
Surface-Active Agents
Rats
Oxygen
Air
55 引用 (Scopus)

Innate immune response to influenza A virus in differentiated human alveolar type II cells

Wang, J., Nikrad, M. P., Phang, T., Gao, B., Alford, T., Ito, Y., Edeen, K., Travanty, E. A., Kosmider, B., Hartshorn, K. & Mason, R. J., 2011 9 1, : : American Journal of Respiratory Cell and Molecular Biology. 45, 3, p. 582-591 10 p.

研究成果: Article

Alveolar Epithelial Cells
Influenza A virus
Viruses
Innate Immunity
Human Influenza
12 引用 (Scopus)

Measurement of serum remnant-like lipoprotein particle-triglyceride (RLP-TG) and RLP-TG/total TG ratio using highly sensitive triglyceride assay reagent

Nakano, T., Tokita, Y., Nagamine, T., Tanaka, A., Okazaki, M., Yatsuzuka, S., Tamei, N., Shimomura, Y., Ando, Y., Akamatsu, S., Fujita, M. Q. & Nakajima, K., 2011 1 14, : : Clinica Chimica Acta. 412, 1-2, p. 71-78 8 p.

研究成果: Article

Lipoproteins
Assays
Triglycerides
Serum
Fasting
26 引用 (Scopus)

Pokkuri Death Syndrome; sudden cardiac death cases without coronary atherosclerosis in South Asian young males

Nakajima, K., Takeichi, S., Nakajima, Y. & Fujita, M. Q., 2011 4 15, : : Forensic Science International. 207, 1-3, p. 6-13 8 p.

研究成果: Article

Sudden Cardiac Death
Coronary Artery Disease
Forensic Medicine
Sudden Death
Lipoproteins
21 引用 (Scopus)

Proteomic analysis of plasma proteins in Japanese semisuper centenarians

Miura, Y., Sato, Y., Arai, Y., Abe, Y., Takayama, M., Toda, T., Hirose, N. & Endo, T., 2011 1, : : Experimental Gerontology. 46, 1, p. 81-85 5 p.

研究成果: Article

Proteomics
Clusterin
Blood Proteins
Haptoglobins
Geriatrics
2010
51 引用 (Scopus)

Altered macrophage function contributes to colitis in mice defective in the phosphoinositide-3 kinase subunit p110δ

Uno, J. K., Rao, K. N., Matsuoka, K., Sheikh, S. Z., Kobayashi, T., Li, F., Steinbach, E. C., Sepulveda, A. R., Vanhaesebroeck, B., Sartor, R. B. & Plevy, S. E., 2010 11, : : Gastroenterology. 139, 5

研究成果: Article

1-Phosphatidylinositol 4-Kinase
Colitis
Macrophages
Phosphatidylinositol 3-Kinases
Interleukin-10
54 引用 (Scopus)

Cutting edge: IFN-γ is a negative regulator of IL-23 in murine macrophages and experimental colitis

Sheikh, S. Z., Matsuoka, K., Kobayashi, T., Li, F., Rubinas, T. & Plevy, S. E., 2010 4 15, : : Journal of Immunology. 184, 8, p. 4069-4073 5 p.

研究成果: Article

Interleukin-23
Colitis
Macrophages
Inflammatory Bowel Diseases
Interleukin-10
20 引用 (Scopus)

MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function

Yamamoto-Furusho, J. K., Barnich, N., Hisamatsu, T. & Podolsky, D. K., 2010, : : Inflammatory Bowel Diseases. 16, 5, p. 736-742 7 p.

研究成果: Article

Defensins
Epithelial Cells
Salmonella typhimurium
Small Interfering RNA
Renilla Luciferases
44 引用 (Scopus)

Production and activation of matrix metalloproteinase 7 (matrilysin 1) in the lungs of patients with idiopathic pulmonary fibrosis

Fujishima, S., Shiomi, T., Yamashita, S., Yogo, Y., Nakano, Y., Inoue, T., Nakamura, M., Tasaka, S., Hasegawa, N., Aikawa, N., Ishizaka, A. & Okada, Y., 2010 8, : : Archives of Pathology and Laboratory Medicine. 134, 8, p. 1136-1142 7 p.

研究成果: Article

Matrix Metalloproteinase 7
Idiopathic Pulmonary Fibrosis
Lung
Epithelial Cells
Interstitial Lung Diseases
13 引用 (Scopus)

Re-elevation of d-dimer as a predictor of re-dissection and venous thromboembolism after Stanford type B acute aortic dissection

Jo, Y., Anzai, T., Ueno, K., Kaneko, H., Kohno, T., Sugano, Y., Maekawa, Y., Yoshikawa, T., Shimizu, H., Yozu, R. & Ogawa, S., 2010 11, : : Heart and Vessels. 25, 6, p. 509-514 6 p.

研究成果: Article

Venous Thromboembolism
Dissection
Hospitalization
Pulmonary Embolism
Blood Pressure
18 引用 (Scopus)
Alveolar Epithelial Cells
Interleukin-13
Surface-Active Agents
Interferons
Protein C
2 引用 (Scopus)

Vitamin D deficiency and lifestyle factors in the oldest old

Sumiya, C., Arai, Y., Takayama, M., Abe, Y., Hirose, N., Asakura, K., Nishiwaki, Y. & Takebayashi, T., 2010 11, : : Journal of the American Geriatrics Society. 58, 11, p. 2242-2244 3 p.

研究成果: Article

Vitamin D Deficiency
Life Style
2009
117 引用 (Scopus)

Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis

Davé, S. H., Tilstra, J. S., Matsuoka, K., Li, F., DeMarco, R. A., Beer-Stolz, D., Sepulveda, A. R., Fink, M. P., Lotze, M. T. & Plevy, S. E., 2009 9 1, : : Journal of Leukocyte Biology. 86, 3, p. 633-643 11 p.

研究成果: Article

HMGB1 Protein
Colitis
Interleukin-10
Cytokines
ethyl pyruvate
2 引用 (Scopus)

Hyperadiponectinemia in alcoholic liver disease: Friend or foe?

Adachi, M. & Ishii, H., 2009, : : Journal of Gastroenterology and Hepatology (Australia). 24, 4, p. 507-508 2 p.

研究成果: Article

Alcoholic Liver Diseases
8 引用 (Scopus)
Lymphoproliferative Disorders
Cerebral Hemorrhage
Graft vs Host Disease
Bone Marrow Transplantation
Human Herpesvirus 4