共同利用研究室

研究成果 1986 2019

2019
1 引用 (Scopus)

Innervation of the tibial epiphysis through the intercondylar foramen

Matsuo, K., Ji, S., Miya, A., Yoda, M., Hamada, Y., Tanaka, T., Takao-Kawabata, R., Kawaai, K., Kuroda, Y. & Shibata, S., 2019 3 1, : : Bone. 120, p. 297-304 8 p.

研究成果: Article

Venus
Epiphyses
Schwann Cells
Sensory Receptor Cells
Knee Joint
2 引用 (Scopus)

Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor-Marked Stromal Population from Adipogenic to Osteoblastic Lineage

Yang, M., Arai, A., Udagawa, N., Zhao, L., Nishida, D., Murakami, K., Hiraga, T., Takao-Kawabata, R., Matsuo, K., Komori, T., Kobayashi, Y., Takahashi, N., Isogai, Y., Ishizuya, T., Yamaguchi, A. & Mizoguchi, T., 2019 1 1, : : Journal of Bone and Mineral Research.

研究成果: Article

Leptin Receptors
Parathyroid Hormone
Mesenchymal Stromal Cells
Population
Osteoblasts
公開
Skull Base
Osteoclasts
Osteoblasts
Posterior Cranial Fossa
Bone and Bones
2018
1 引用 (Scopus)

Bone Marrow Cells Inhibit BMP-2-Induced Osteoblast Activity in the Marrow Environment

Nguyen, H. T., Ono, M., Oida, Y., Hara, E. S., Komori, T., Akiyama, K., Nguyen, H. T. T., Aung, K. T., Pham, H. T., Tosa, I., Takarada, T., Matsuo, K., Mizoguchi, T., Oohashi, T. & Kuboki, T., 2018 1 1, (Accepted/In press) : : Journal of Bone and Mineral Research.

研究成果: Article

Bone Morphogenetic Protein 2
Osteoblasts
Bone Marrow Cells
Bone Marrow
Osteogenesis
8 引用 (Scopus)

Effects of long-term cigarette smoke exposure on bone metabolism, structure, and quality in a mouse model of emphysema

Sasaki, M., Chubachi, S., Kameyama, N., Sato, M., Haraguchi, M., Miyazaki, M., Takahashi, S., Nakano, T., Kuroda, Y., Betsuyaku, T. & Matsuo, K., 2018 1 1, : : PLoS One. 13, 1, e0191611.

研究成果: Article

bone metabolism
cigarettes
Emphysema
smoke
Metabolism
3 引用 (Scopus)

HER2 heterogeneity is associated with poor survival in HER2-positive breast cancer

Hosonaga, M., Arima, Y., Sampetrean, O., Komura, D., Koya, I., Sasaki, T., Sato, E., Okano, H., Kudo, J., Ishikawa, S., Saya, H. & Ishikawa, T., 2018 8 1, : : International Journal of Molecular Sciences. 19, 8, 2158.

研究成果: Article

breast
cancer
Breast Neoplasms
mice
RNA Sequence Analysis

Intragenic copy number variation within human epiplakin 1 (EPPK1) generates variation of molecular size of epiplakin

Ishikawa, K., Furuhashi, M., Sasaki, T., Kudo, J., Tsuchisaka, A., Hashimoto, T., Sasaki, T., Yoshioka, H., Eshima, N., Matsuda-Hirose, H., Sakai, T., Hatano, Y. & Fujiwara, S., 2018 8 1, : : Journal of Dermatological Science. 91, 2, p. 228-231 4 p.

研究成果: Letter

epiplakin
2017
4 引用 (Scopus)
Ear Ossicles
Dissection
Audition
Middle Ear
Blister
5 引用 (Scopus)

Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy

Yang, M., Arai, A., Udagawa, N., Hiraga, T., Lijuan, Z., Ito, S., Komori, T., Moriishi, T., Matsuo, K., Shimoda, K., Zahalka, A. H., Kobayashi, Y., Takahashi, N. & Mizoguchi, T., 2017 12 1, : : Scientific Reports. 7, 1, 4928.

研究成果: Article

Leptin Receptors
Mesenchymal Stromal Cells
Osteoblasts
Population
Bone and Bones
2 引用 (Scopus)
Ephrins
Periodontal Ligament
Porphyromonas gingivalis
Lipopolysaccharides
Fibroblasts
7 引用 (Scopus)

Protective efficacy of a hydroxy fatty acid against gastric Helicobacter infections

Matsui, H., Takahashi, T., Murayama, S. Y., Kawaguchi, M., Matsuo, K. & Nakamura, M., 2017 12 1, : : Helicobacter. 22, 6, e12430.

研究成果: Article

Hydroxy Acids
Helicobacter Infections
Stomach
Pylorus
Fatty Acids
10 引用 (Scopus)
RNA Sequence Analysis
Cellular Microenvironment
Melanoma
Brain
RNA
19 引用 (Scopus)

Simvastatin-induced apoptosis in osteosarcoma cells: A key role of rhoa-ampk/p38 mapk signaling in antitumor activity

Kamel, W. A., Sugihara, E., Nobusue, H., Yamaguchi-Iwai, S., Onishi, N., Maki, K., Fukuchi, Y., Matsuo, K., Muto, A., Saya, H. & Shimizu, T., 2017 1 1, : : Molecular Cancer Therapeutics. 16, 1, p. 182-192 11 p.

研究成果: Article

Simvastatin
Osteosarcoma
AMP-Activated Protein Kinases
Apoptosis
p38 Mitogen-Activated Protein Kinases
2016
2 引用 (Scopus)

Flesh-eating Streptococcus pyogenes triggers the expression of receptor activator of nuclear factor-κB ligand

Matsui, H., Nakatani, Y., Yoshida, H., Takizawa, A., Takeuchi, O., Øverby, A., Takahashi, T., Murayama, S. Y. & Matsuo, K., 2016 10 1, : : Cellular Microbiology. 18, 10, p. 1390-1404 15 p.

研究成果: Article

Streptococcus pyogenes
Cytoplasmic and Nuclear Receptors
Eating
Ligands
Bone and Bones
30 引用 (Scopus)

Osteocyte-directed bone demineralization along canaliculi

Nango, N., Kubota, S., Hasegawa, T., Yashiro, W., Momose, A. & Matsuo, K., 2016 3 1, : : Bone. 84, p. 279-288 10 p.

研究成果: Article

Osteocytes
Bone Matrix
Bone and Bones
Osteoclasts
Minerals
4 引用 (Scopus)

Osteoprotegerin regulates pancreatic β-cell homeostasis upon microbial invasion

Kuroda, Y., Maruyama, K., Fujii, H., Sugawara, I., Ko, S., Yasuda, H., Matsui, H. & Matsuo, K., 2016 1 11, : : PLoS One. 11, 1, e0146544.

研究成果: Article

Osteoprotegerin
lipopolysaccharides
homeostasis
Homeostasis
insulin secretion
80 引用 (Scopus)

SAMD9 mutations cause a novel multisystem disorder, MIRAGE syndrome, and are associated with loss of chromosome 7

Narumi, S., Amano, N., Ishii, T., Katsumata, N., Muroya, K., Adachi, M., Toyoshima, K., Tanaka, Y., Fukuzawa, R., Miyako, K., Kinjo, S., Ohga, S., Ihara, K., Inoue, H., Kinjo, T., Hara, T., Kohno, M., Yamada, S., Urano, H., Kitagawa, Y. および19人, Tsugawa, K., Higa, A., Miyawaki, M., Okutani, T., Kizaki, Z., Hamada, H., Kihara, M., Shiga, K., Yamaguchi, T., Kenmochi, M., Kitajima, H., Fukami, M., Shimizu, A., Kudo, J., Shibata, S., Okano, H., Miyake, N., Matsumoto, N. & Hasegawa, T., 2016 5 16, (Accepted/In press) : : Nature Genetics.

研究成果: Article

Chromosomes, Human, Pair 7
Mutation
Endosomes
Growth
Exome
2015
5 引用 (Scopus)

A novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclasts

Matsushita, M., Ozaki, Y., Hasegawa, Y., Terada, F., Tabata, N., Shiheido, H., Yanagawa, H., Oikawa, T., Matsuo, K., Du, W., Yamada, T., Hozumi, M., Ichikawa, D. & Hattori, Y., 2015 1 24, : : PLoS One. 10, 1, e0116135.

研究成果: Article

phthalimide
myeloma
osteoclasts
Osteoclasts
Multiple Myeloma
Osteocytes
Physiologic Calcification
Cell Biology
Bone and Bones
Synchrotrons
16 引用 (Scopus)

EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance

Nguyen, T. M., Arthur, A., Panagopoulos, R., Paton, S., Hayball, J. D., Zannettino, A. C. W., Purton, L. E., Matsuo, K. & Gronthos, S., 2015 9 1, : : Stem Cells. 33, 9, p. 2838-2849 12 p.

研究成果: Article

Stromal Cells
Hematopoietic Stem Cells
Maintenance
Ephrin-B2
Cell Culture Techniques
23 引用 (Scopus)

Genomewide comprehensive analysis reveals critical cooperation between smad and c-Fos in RANKL-induced osteoclastogenesis

Omata, Y., Yasui, T., Hirose, J., Izawa, N., Imai, Y., Matsumoto, T., Masuda, H., Tokuyama, N., Nakamura, S., Tsutsumi, S., Yasuda, H., Okamoto, K., Takayanagi, H., Hikita, A., Imamura, T., Matsuo, K., Saito, T., Kadono, Y., Aburatani, H. & Tanaka, S., 2015 5 1, : : Journal of Bone and Mineral Research. 30, 5, p. 869-877 9 p.

研究成果: Article

Transforming Growth Factors
Osteogenesis
NFATC Transcription Factors
Chromatin Immunoprecipitation
Formaldehyde
19 引用 (Scopus)

IRBIT regulates CaMKIIα activity and contributes to catecholamine homeostasis through tyrosine hydroxylase phosphorylation

Kawaai, K., Mizutani, A., Shoji, H., Ogawa, N., Ebisui, E., Kuroda, Y., Wakana, S., Miyakawa, T., Hisatsune, C. & Mikoshiba, K., 2015 4 28, : : Proceedings of the National Academy of Sciences of the United States of America. 112, 17, p. 5515-5520 6 p.

研究成果: Article

Calcium-Calmodulin-Dependent Protein Kinases
Tyrosine 3-Monooxygenase
Catecholamines
Homeostasis
Phosphorylation
82 引用 (Scopus)

Long-term safety issues of iPSC-based cell therapy in a spinal cord injury model: Oncogenic transformation with epithelial-mesenchymal transition

Nori, S., Okada, Y., Nishimura, S., Sasaki, T., Itakura, G., Kobayashi, Y., Renault-Mihara, F., Shimizu, A., Koya, I., Yoshida, R., Kudo, J., Koike, M., Uchiyama, Y., Ikeda, E., Toyama, Y., Nakamura, M. & Okano, H., 2015 3 10, : : Stem Cell Reports. 4, 3, p. 360-373 14 p.

研究成果: Article

Induced Pluripotent Stem Cells
Epithelial-Mesenchymal Transition
Cell- and Tissue-Based Therapy
Stem cells
Spinal Cord Injuries
10 引用 (Scopus)

Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus

Matsuo, K., Kuroda, Y., Nango, N., Shimoda, K., Kubota, Y., Ema, M., Bakiri, L., Wagner, E. F., Takeda, Y., Yashiro, W. & Momose, A., 2015 11 15, : : Development (Cambridge). 142, 22, p. 3912-3920 9 p.

研究成果: Article

Malleus
Growth Plate
Osteogenesis
Osteoblasts
Bone Matrix
9 引用 (Scopus)

Pathological characterization of pachydermia in pachydermoperiostosis

Tanese, K., Niizeki, H., Seki, A., Otsuka, A., Kabashima, K., Kosaki, K., Kuwahara, M., Miyakawa, S. I., Miyasaka, M., Matsuoka, K., Okuyama, T., Shiohama, A., Sasaki, T., Kudo, J., Amagai, M. & Ishiko, A., 2015 7 1, : : Journal of Dermatology. 42, 7, p. 710-714 5 p.

研究成果: Article

Primary Hypertrophic Osteoarthropathy
Elastic Tissue
Mucins
Skin
Edema
2014
4 引用 (Scopus)
Osteocytes
Osteolysis
Glucocorticoids
Bone and Bones
Dendrites
15 引用 (Scopus)

Dramatic improvement in genome assembly achieved using doubled-haploid genomes

Zhang, H., Tan, E., Suzuki, Y., Hirose, Y., Kinoshita, S., Okano, H., Kudo, J., Shimizu, A., Saito, K., Watabe, S. & Asakawa, S., 2014 10 27, : : Scientific Reports. 4, 6780.

研究成果: Article

Haploidy
Genome
Takifugu
4 引用 (Scopus)

Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1

Negishi, N., Suzuki, D., Ito, R., Irie, N., Matsuo, K., Yahata, T., Nagano, K., Aoki, K., Ohya, K., Hozumi, K., Ando, K., Tamaoki, N., Ito, M. & Habu, S., 2014, : : Experimental Hematology. 42, 6

研究成果: Article

Hematopoietic Stem Cells
Bone Marrow
Interleukin Receptor Common gamma Subunit
Wiskott-Aldrich Syndrome
Severe Combined Immunodeficiency
21 引用 (Scopus)

Filaggrin loss-of-function mutations are not a predisposing factor for atopic dermatitis in an Ishigaki Island under subtropical climate

Sasaki, T., Furusyo, N., Shiohama, A., Takeuchi, S., Nakahara, T., Uchi, H., Hirota, T., Tamari, M., Shimizu, N., Ebihara, T., Amagai, M., Furue, M., Hayashi, J. & Kudo, J., 2014, : : Journal of Dermatological Science. 76, 1, p. 10-15 6 p.

研究成果: Article

Atopic Dermatitis
Climate
Islands
Causality
Mutation
12 引用 (Scopus)

Global gene expression analysis following spinal cord injury in non-human primates

Nishimura, S., Sasaki, T., Shimizu, A., Yoshida, K., Iwai, H., Koya, I., Kobayashi, Y., Itakura, G., Shibata, S., Ebise, H., Horiuchi, K., Kudo, J., Toyama, Y., Anderson, A. J., Okano, H. & Nakamura, M., 2014, : : Experimental Neurology. 261, p. 171-179 9 p.

研究成果: Article

Spinal Cord Injuries
Primates
Gene Expression
Callithrix
Rodentia
23 引用 (Scopus)

IGF2 preserves osteosarcoma cell survival by creating an autophagic state of dormancy that protects cells against chemotherapeutic stress

Shimizu, T., Sugihara, E., Yamaguchi-Iwai, S., Tamaki, S., Koyama, Y., Kamel, W., Ueki, A., Ishikawa, T., Chiyoda, T., Osuka, S., Onishi, N., Ikeda, H., Kamei, J., Matsuo, K., Fukuchi, Y., Nagai, T., Toguchida, J., Toyama, Y., Muto, A. & Saya, H., 2014 11 15, : : Cancer Research. 74, 22, p. 6531-6541 11 p.

研究成果: Article

Osteosarcoma
Cell Survival
Autophagy
Glutamine
Insulin
6 引用 (Scopus)

In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes

Yamaguchi, Y., Kudo, J., Yoshida, T. & Shimizu, N., 2014 11 15, : : Biology Open. 3, 11, p. 1071-1082 12 p.

研究成果: Article

thymocytes
coculture
Thymocytes
Coculture Techniques
epithelial cells
34 引用 (Scopus)

Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation

Akiyama, N., Shinzawa, M., Miyauchi, M., Yanai, H., Tateishi, R., Shimo, Y., Ohshima, D., Matsuo, K., Sasaki, I., Hoshino, K., Wu, G., Yagi, S., Inoue, J. I., Kaisho, T. & Akiyama, T., 2014, : : Journal of Experimental Medicine. 211, 12, p. 2425-2438 14 p.

研究成果: Article

Immune Tolerance
Epithelial Cells
Osteoprotegerin
Autoimmunity
Immunity
22 引用 (Scopus)
Transcription Factor AP-1
Oxidoreductases
Pharmaceutical Preparations
Small Interfering RNA
Neoplasms
16 引用 (Scopus)

The complete type of pachydermoperiostosis: A novel nonsense mutation p.E141* of the SLCO2A1 gene

Niizeki, H., Shiohama, A., Sasaki, T., Seki, A., Kabashima, K., Otsuka, A., Kosaki, K., Ogo, A., Yamada, T., Miyasaka, M., Matsuoka, K., Hirakiyama, A., Okuyama, T., Matsuda, M., Nakabayashi, K., Tanese, K., Ishiko, A., Amagai, M. & Kudo, J., 2014, : : Journal of Dermatological Science. 75, 3, p. 193-195 3 p.

研究成果: Article

Hydroxyprostaglandin Dehydrogenases
Organic Anion Transporters
Dinoprostone
Introns
Exons
3 引用 (Scopus)

The in vivo effect of prophylactic subchondral bone protection of osteoarthritic synovial membrane in bone-specific Ephb4-overexpressing mice

Valverde-Franco, G., Hum, D., Matsuo, K., Lussier, B., Pelletier, J. P., Fahmi, H., Kapoor, M. & Martel-Pelletier, J., 2014, : : American Journal of Pathology. 185, 2, p. 335-346 12 p.

研究成果: Article

Synovial Membrane
Osteoarthritis
Tibial Meniscus
Bone and Bones
Collagen Type III
15 引用 (Scopus)

The novel SLCO2A1 heterozygous missense mutation p.E427K and nonsense mutation p.R603* in a female patient with pachydermoperiostosis with an atypical phenotype

Niizeki, H., Shiohama, A., Sasaki, T., Seki, A., Kabashima, K., Otsuka, A., Takeshita, M., Hirakiyama, A., Okuyama, T., Tanese, K., Ishiko, A., Amagai, M. & Kudo, J., 2014, : : British Journal of Dermatology. 170, 5, p. 1187-1189 3 p.

研究成果: Article

Primary Hypertrophic Osteoarthropathy
Organic Anion Transporters
Nonsense Codon
Missense Mutation
Heterozygote
2013
1 引用 (Scopus)

[Osteoimmunologic regulation of aging].

Matsuo, K., 2013 1, : : Clinical calcium. 23, 1, p. 59-64 6 p.

研究成果: Article

Osteoprotegerin
Bone Marrow
Osteoclasts
Inflammation
Bone and Bones
2 引用 (Scopus)
Physiologic Calcification
Osteomalacia
Rickets
Collagen
Durapatite
18 引用 (Scopus)

Acquired expression of NFATc1 downregulates e-cadherin and promotes cancer cell invasion

Oikawa, T., Nakamura, A., Onishi, N., Yamada, T., Matsuo, K. & Saya, H., 2013 8 15, : : Cancer Research. 73, 16, p. 5100-5109 10 p.

研究成果: Article

Cadherins
Down-Regulation
Neoplasms
Macrophages
T-Lymphocytes
62 引用 (Scopus)
Nonsense Codon
Eczema
Secretory Vesicles
Atopic Dermatitis
Theoretical Models
5 引用 (Scopus)

Assessment of homozygosity levels in the mito-gynogenetic torafugu (Takifugu rubripes) by genome-wide SNP analyses

Zhang, H., Hirose, Y., Yoshino, R., Kinoshita, S., Saito, K., Tan, E., Suzuki, Y., Shimizu, A., Okano, H., Kudo, J., Watabe, S. & Asakawa, S., 2013 3 4, : : Aquaculture. 380-383, p. 114-119 6 p.

研究成果: Article

Takifugu rubripes
homozygosity
single nucleotide polymorphism
polymorphism
genome
9 引用 (Scopus)

Characterization of canine filaggrin: Gene structure and protein expression in dog skin

Kanda, S., Sasaki, T., Shiohama, A., Nishifuji, K., Amagai, M., Iwasaki, T. & Kudo, J., 2013 2, : : Veterinary Dermatology. 24, 1

研究成果: Article

skin (animal)
Canidae
protein synthesis
Dogs
Skin
53 引用 (Scopus)

Diverse spectrum of rare deafness genes underlies early-childhood hearing loss in Japanese patients: A cross-sectional, multi-center next-generation sequencing study

Mutai, H., Suzuki, N., Shimizu, A., Torii, C., Namba, K., Morimoto, N., Kudo, J., Kaga, K., Kosaki, K. & Matsunaga, T., 2013, : : Orphanet Journal of Rare Diseases. 8, 1, 172.

研究成果: Article

Deafness
Hearing Loss
Genes
Mutation
DNA
26 引用 (Scopus)

EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repair

Arthur, A., Panagopoulos, R. A., Cooper, L., Menicanin, D., Parkinson, I. H., Codrington, J. D., Vandyke, K., Zannettino, A. C. W., Koblar, S. A., Sims, N. A., Matsuo, K. & Gronthos, S., 2013 4, : : Journal of Bone and Mineral Research. 28, 4, p. 926-935 10 p.

研究成果: Article

Bone Fractures
Osteogenesis
Bone and Bones
Bony Callus
Osteoclasts
52 引用 (Scopus)

Mutations in SERPINB7, encoding a member of the serine protease inhibitor superfamily, cause nagashima-type palmoplantar keratosis

Kubo, A., Shiohama, A., Sasaki, T., Nakabayashi, K., Kawasaki, H., Atsugi, T., Sato, S., Shimizu, A., Mikami, S., Tanizaki, H., Uchiyama, M., Maeda, T., Taisuke, I., Sakabe, J. I., Heike, T., Okuyama, T., Kosaki, R., Kosaki, K., Kudo, J., Hata, K. および7人, Umezawa, A., Tokura, Y., Ishiko, A., Niizeki, H., Kabashima, K., Mitsuhashi, Y. & Amagai, M., 2013 11 7, : : American Journal of Human Genetics. 93, 5, p. 945-956 12 p.

研究成果: Article

Palmoplantar Keratoderma
Serine Proteinase Inhibitors
Mutation
Cornea
Peptide Hydrolases
11 引用 (Scopus)

Regulation of human autoimmune regulator (AIRE) gene translation by miR-220b

Matsuo, T., Noguchi, Y., Shindo, M., Morita, Y., Oda, Y., Yoshida, E., Hamada, H., Harada, M., Shiokawa, Y., Nishida, T., Tominaga, R., Kikushige, Y., Akashi, K., Kudo, J., Shimizu, N., Tanaka, Y., Umemura, T., Taniguchi, T., Yoshimura, A., Kobayashi, T. および4人, Mitsuyama, M., Kurisaki, H., Katsuta, H. & Nagafuchi, S., 2013 11 1, : : Gene. 530, 1, p. 19-25 7 p.

研究成果: Article

Regulator Genes
3' Untranslated Regions
Autoimmune Polyendocrinopathies
Proteins
Mutation
21 引用 (Scopus)

Regulation of osteoclasts by membrane-derived lipid mediators

Oikawa, T., Kuroda, Y. & Matsuo, K., 2013 9, : : Cellular and Molecular Life Sciences. 70, 18, p. 3341-3353 13 p.

研究成果: Article

Osteoclasts
Membrane Lipids
Phosphatidylinositols
Osteogenesis
Osteopetrosis
8 引用 (Scopus)

Talbot-defocus multiscan tomography using the synchrotron X-ray microscope to study the lacuno-canalicular network in mouse bone

Nango, N., Kubota, S., Takeuchi, A., Suzuki, Y., Yashiro, W., Momose, A. & Matsuo, K., 2013, : : Biomedical Optics Express. 4, 6, p. 917-923 7 p.

研究成果: Article

Osteocytes
Synchrotrons
bones
mice
Physiologic Calcification
2012
1 引用 (Scopus)

[Osteocytic osteolysis: measurements of the volume of osteocytic lacunae].

Matsuo, K. & Nango, N., 2012 5, : : Clinical calcium. 22, 5, p. 677-683 7 p.

研究成果: Article

Osteolysis
Osteocytes
Bone and Bones
Osteoclasts
Hibernation