先端医科学研究所

2003

Human circulating CD14⁺ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation

Kuwana, M., Okazaki, Y., Kodama, H., Izumi, K., Yasuoka, H., Ogawa, Y., Kawakami, Y. & Ikeda, Y., 2003 11月 1, In: Journal of Leukocyte Biology. 74, 5, p. 833-845 13 p.

研究成果: Article › 査読

260 被引用数 (Scopus)

Periductal area as the primary site for T-cell activation in lacrimal gland chronic graft-versus-host disease

Ogawa, Y., Kuwana, M., Yamazaki, K., Mashima, Y., Yamada, M., Mori, T., Okamoto, S., Oguchi, Y. & Kawakami, Y., 2003 5月 1, In: Investigative Ophthalmology and Visual Science. 44, 5, p. 1888-1896 9 p.

研究成果: Article › 査読

88 被引用数 (Scopus)

Results of a phase I clinical study using autologous tumour lysate-pulsed monocyte-derived mature dendritic cell vaccinations for stage IV malignant melanoma patients combined with low dose interleukin-2

Nagayama, H., Sato, K., Morishita, M., Uchimaru, K., Oyaizu, N., Inazawa, T., Yamasaki, T., Enomoto, M., Nakaoka, T., Nakamura, T., Maekawa, T., Yamamoto, A., Shimada, S., Saida, T., Kawakami, Y., Asano, S., Tani, K., Takahashi, T. A. & Yamashita, N., 2003 10月, In: Melanoma Research. 13, 5, p. 521-530 10 p.

研究成果: Article › 査読

67 被引用数 (Scopus)

Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability

Ishikawa, T., Fujita, T., Suzuki, Y., Okabe, S., Yuasa, Y., Iwai, T. & Kawakami, Y., 2003 9月 1, In: Cancer Research. 63, 17, p. 5564-5572 9 p.

研究成果: Article › 査読

105 被引用数 (Scopus)

2002

Autoantibody to c-Mpl (thrombopoietin receptor) in systemic lupus erythematosus: Relationship to thrombocytopenia with megakaryocytic hypoplasia

Kuwana, M., Okazaki, Y., Kajihara, M., Kaburaki, J., Miyazaki, H., Kawakami, Y. & Ikeda, Y., 2002 8月, In: Arthritis and Rheumatism. 46, 8, p. 2148-2159 12 p.

研究成果: Article › 査読

63 被引用数 (Scopus)

Development of immunotherapy using allogeneic antigens for hematological malignancy

Matsushita, M., Yamazaki, R., Fujita, T. & Kawakami, H., 2002 2月, In: [Rinshō ketsueki] The Japanese journal of clinical hematology. 43, 2, p. 94-96 3 p.

研究成果: Article › 査読

Dry eye associated with chronic graft-versus-host disease

Ogawa, Y., Kuwana, M., Yamazaki, K., Mashima, Y., Okamoto, S., Tsubota, K., Oguchi, Y. & Kawakami, Y., 2002 12月 1, In: Advances in experimental medicine and biology. 506 B, p. 1041-1045 5 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Identification of an immunodominant epitope on RNA polymerase III recognized by systemic sclerosis sera: Application to enzyme-linked immunosorbent assay

Kuwana, M., Kimura, K. & Kawakami, Y., 2002 10月 1, In: Arthritis and Rheumatism. 46, 10, p. 2742-2747 6 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

Identification of tumor antigens recognized by T cells and their use for analysis of anti-tumor responses

Fujita, T. & Kawakami, Y., 2002 9月 1, In: Biotherapy. 16, 5, p. 441-448 8 p.

研究成果: Article › 査読

Spleen is a primary site for activation of platelet-reactive T and B cells in patients with immune thrombocytopenic purpura

Kuwana, M., Okazaki, Y., Kaburaki, J., Kawakami, Y. & Ikeda, Y., 2002 4月 1, In: Journal of Immunology. 168, 7, p. 3675-3682 8 p.

研究成果: Article › 査読

Open Access

120 被引用数 (Scopus)

2001

A significant role of stromal fibroblasts in rapidly progressive dry eye in patients with chronic GVHD

Ogawa, Y., Yamazaki, K., Kuwana, M., Mashima, Y., Nakamura, Y., Ishida, S., Toda, I., Oguchi, Y., Tsubota, K., Okamoto, S. & Kawakami, Y., 2001 1月 30, In: Investigative Ophthalmology and Visual Science. 42, 1, p. 111-119 9 p.

研究成果: Article › 査読

121 被引用数 (Scopus)

Autoantibodies to the amino-terminal fragment of β-fodrin expressed in glandular epithelial cells in patients with Sjögren's syndrome

Kuwana, M., Okano, T., Ogawa, Y., Kaburaki, J. & Kawakami, Y., 2001 11月 1, In: Journal of Immunology. 167, 9, p. 5449-5456 8 p.

研究成果: Article › 査読

Open Access

30 被引用数 (Scopus)

Clinical significance of MART-1 and HLA-A2 expression and CD8+ T cell infiltration in melanocytic lesions in HLA-A2 phenotype patients

Kageshita, T., Kawakami, Y. & Ono, T., 2001, In: Journal of Dermatological Science. 25, 1, p. 36-44 9 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Expression of the neural RNA- binding protein Musashi1 in human gliomas

Toda, M., Iizuka, Y., Yu, W., Imai, T., Ikeda, E., Yoshida, K., Kawase, T., Kawakami, Y., Okano, H. & Uyemura, K., 2001, In: Glia. 34, 1, p. 1-7 7 p.

研究成果: Article › 査読

137 被引用数 (Scopus)

Induction of antigen-specific human CD4⁺ T cell anergy by peripheral blood DC2 precursors

Kuwana, M., Kaburaki, J., Wright, T. M., Kawakami, Y. & Ikeda, Y., 2001, In: European Journal of Immunology. 31, 9, p. 2547-2557 11 p.

研究成果: Article › 査読

127 被引用数 (Scopus)

Isolation of a new melanoma antigen, MART-2, containing a mutated epitope recognized by autologous tumor-infiltrating T lymphocytes

Kawakami, Y., Wang, X., Shofuda, T., Sumimoto, H., Tupesis, J. P., Fitzgerald, E. & Rosenberg, S. A., 2001 2月 15, In: Journal of Immunology. 166, 4, p. 2871-2877 7 p.

研究成果: Article › 査読

Open Access

58 被引用数 (Scopus)

Quantitative monitoring of the PRAME gene for the detection of minimal residual disease in leukaemia

Matsushita, M., Ikeda, H., Kizaki, M., Okamoto, S., Ogasawara, M., Ikeda, Y. & Kawakami, Y., 2001, In: British Journal of Haematology. 112, 4, p. 916-926 11 p.

研究成果: Article › 査読

72 被引用数 (Scopus)

Recent topics on basic research for idiopathic thrombocytopenic purpura

Kuwana, M., Kawakami, Y. & Ikeda, Y., 2001 10月, In: Rinsho byori. The Japanese journal of clinical pathology. 49, 10, p. 992-995 4 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Tumor antigens isolated from a patient with vitiligo and T-cell-infiltrated melanoma

Kiniwa, Y., Fujita, T., Akada, M., Ito, K., Shofuda, T., Suzuki, Y., Yamamoto, A., Saida, T. & Kawakami, Y., 2001 11月 1, In: Cancer Research. 61, 21, p. 7900-7907 8 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

2000

Cancer immunotherapy with dendritic cells engineered to express tumor antigens

Sumimoto, H. & Kawakami, Y., 2000 12月 1, In: Biotherapy. 14, 12, p. 1197-1204 8 p.

研究成果: Article › 査読

HLA class II alleles in Japanese patients with immune thrombocytopenic purpura. Associations with anti-platelet glycoprotein autoantibodies and responses to splenectomy

Kuwana, M., Kaburaki, J., Pandey, J. P., Murata, M., Kawakami, Y., Inoko, H. & Ikeda, Y., 2000, In: Tissue Antigens. 56, 4, p. 337-343 7 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Identification and characterization of pathogenic autoreactive T cells in patients with idiopathic thrombocytopenic purpura

Kuwana, M., Kawakami, Y. & Ikeda, Y., 2000, In: Japanese Journal of Clinical Immunology. 23, 6, p. 555-557 3 p.

研究成果: Article › 査読

Open Access

Longitudinal analysis of autoantibody response to topoisomerase I in systemic sclerosis

Kuwana, M., Kaburaki, J., Mimori, T., Kawakami, Y. & Tojo, T., 2000 5月, In: Arthritis and Rheumatism. 43, 5, p. 1074-1084 11 p.

研究成果: Article › 査読

100 被引用数 (Scopus)

Molecular analysis of a candidate metastasis-associated gene, MTA1: Possible interaction with histone deacetylase 1

Toh, Y., Kuninaka, S., Endo, K., Oshiro, T., Ikeda, Y., Nakashima, H., Baba, H., Kohnoe, S., Okamura, T., Nicolson, G. L. & Sugimachi, K., 2000 3月 1, In: Journal of Experimental and Clinical Cancer Research. 19, 1, p. 105-111 7 p.

研究成果: Article › 査読

69 被引用数 (Scopus)

New cancer therapy by immunomanipulation: Development of immunotherapy for human melanoma as a model system

Kawakami, Y., 2000 5月 1, In: Cornea. 19, 3 SUPPL. 1, p. S2-S6

研究成果: Article › 査読

15 被引用数 (Scopus)

Overexpression of manganese superoxide dismutase mRNA may correlate with aggressiveness in gastric and colorectal adenocarcinomas.

Toh, Y., Kuninaka, S., Oshiro, T., Ikeda, Y., Nakashima, H., Baba, H., Kohnoe, S., Okamura, T., Mori, M. & Sugimachi, K., 2000 7月, In: International journal of oncology. 17, 1, p. 107-112 6 p.

研究成果: Article › 査読

75 被引用数 (Scopus)

Recognition of shared melanoma antigens in association with major hla-a alleles by tumor infiltrating t lymphocytes from 123 patients with melanoma

Kawakami, Y., Dang, N., Wang, X., Tupesis, J., Robbins, P. F., Wang, R. F., Wunderlich, J. R., Yannelli, J. R. & Rosenberg, S. A., 2000 1月, In: Journal of Immunotherapy. 23, 1, 1 p.

研究成果: Article › 査読

Recognition of shared melanoma antigens in association with major HLA-A alleles by tumor infiltrating T lymphocytes from 123 patients with melanoma

Kawakami, Y., Dang, N., Wang, X., Tupesis, J., Robbins, P. F., Wang, R. F., Wunderlich, J. R., Yannelli, J. R. & Rosenberg, S. A., 2000 2月 15, In: Journal of Immunotherapy. 23, 1, p. 17-27 11 p.

研究成果: Article › 査読

87 被引用数 (Scopus)

Reduced expression of manganese superoxide dismutase mRNA may correlate with invasiveness in esophageal carcinoma

Toh, Y., Kuninaka, S., Mori, M., Oshiro, T., Ikeda, Y., Nakashima, H., Baba, H., Kohnoe, S., Okamura, T. & Sugimachi, K., 2000 1月 1, In: Oncology. 59, 3, p. 223-228 6 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Serum interleukin-18 levels are elevated in schizophrenia

Tanaka, K. F., Shintani, F., Fujii, Y., Yagi, G. & Asai, M., 2000 9月 25, In: Psychiatry Research. 96, 1, p. 75-80 6 p.

研究成果: Article › 査読

62 被引用数 (Scopus)

Suppression of manganese superoxide dismutase augments sensitivity to radiation, hyperthermia and doxorubicin in colon cancer cell lines by inducing apoptosis

Kuninaka, S., Ichinose, Y., Koja, K. & Toh, Y., 2000, In: British Journal of Cancer. 83, 7, p. 928-934 7 p.

研究成果: Article › 査読

Open Access

59 被引用数 (Scopus)

T cell immune responses against melanoma and melanocytes in cancer and autoimmunity

Kawakami, Y., Suzuki, Y., Shofuda, T., Kiniwa, Y., Inozume, T., Dan, K., Sakurai, T. & Fujita, T., 2000, In: Pigment Cell Research. 13, SUPPL. 8, p. 163-169 7 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

The influence of enhanced postoperative inflammation by the intrapleural administration of streptococcal preparation (OK-432) on the prognosis of completely resected non-small-cell lung cancer

Uehara, T., Yano, T., Kuninaka, S., Yoshino, I., Asoh, H. & Ichinose, Y., 2000 10月 13, In: Journal of Surgical Oncology. 75, 1, p. 51-54 4 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

1999

Key points for development of immunotherapy for cancer using T cell defined tumor antigens

Kawakami, Y., 1999 6月 26, In: Biotherapy. 13, 5, p. 429-433 5 p.

研究成果: Article › 査読

Transcription initiation mediated by initiator binding protein in Saccharomyces cerevisiae

Ohishi-Shofuda, T., Suzuki, Y., Yano, K. I., Sakurai, H. & Fukasawa, T., 1999 2月 5, In: Biochemical and Biophysical Research Communications. 255, 1, p. 157-163 7 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

1998

HLA class I and class II expression of pulmonary adenocarcinoma cells and the influence of interferon gamma

Yano, T., Fukuyama, Y., Yokoyama, H., Kuninaka, S., Asoh, H., Katsuda, Y. & Ichinose, Y., 1998 6月, In: Lung Cancer. 20, 3, p. 185-190 6 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Identification of a shared HLA-A*0201-restricted T-cell epitope from the melanoma antigen tyrosinase-related protein 2 (TRP2)

Parkhurst, M. R., Fitzgerald, E. B., Southwood, S., Sette, A., Rosenberg, S. A. & Kawakami, Y., 1998 11月 1, In: Cancer Research. 58, 21, p. 4895-4901 7 p.

研究成果: Article › 査読

166 被引用数 (Scopus)

Identification of new melanoma epitopes on melanosomal proteins recognized by tumor infiltrating T lymphocytes restricted by HLA-A1, -A2, and -A3 alleles

Kawakami, Y., Robbins, P. F., Wang, X., Tupesis, J. P., Parkhurst, M. R., Kang, X., Sakaguchi, K., Appella, E. & Rosenberg, S. A., 1998 12月 15, In: Journal of Immunology. 161, 12, p. 6985-6992 8 p.

研究成果: Article › 査読

99 被引用数 (Scopus)

Immunotherapy using human melanoma epitopes recognized by T cells

Kawakami, Y., 1998 1月 1, In: Biotherapy. 12, 5, p. 542-548 7 p.

研究成果: Article › 査読

1997

Differential expression of MART-1 in primary and metastatic melanoma lesions

Kageshita, T., Kawakami, Y., Hirai, S. & Ono, T., 1997 1月 1, In: Journal of Immunotherapy. 20, 6, p. 460-465 6 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

Failure in resection of multiple pulmonary metastases from colorectal cancer

Yano, T., Fukuyama, Y., Yokoyama, H., Tanaka, Y., Miyagi, J., Kuninaka, S., Asoh, H. & Ichinose, Y., 1997 1月 1, In: Journal of the American College of Surgeons. 185, 2, p. 120-122 3 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Identification of Subdominant CTL Epitopes of the GP100 Melanoma-Associated Tumor Antigen by Primary in Vitro Immunization with Peptide-Pulsed Dendritic Cells

Tsai, V., Southwood, S., Sidney, J., Sakaguchi, K., Kawakami, Y., Appella, E., Sette, A. & Celis, E., 1997 2月 15, In: Journal of Immunology. 158, 4, p. 1796-1802 7 p.

研究成果: Article › 査読

170 被引用数 (Scopus)

Induction of melanoma reactive T cells by stimulator cells expressing melanoma epitope-major histocompatibility complex class I fusion proteins

Kang, X., Robbins, P. F., Fitzgerald, E. B., Wang, R. F., Rosenberg, S. A. & Kawakami, Y., 1997 1月 28, In: Cancer Research. 57, 2, p. 202-205 4 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Inhalation therapy using a streptococcal preparation (OK-432) against bronchiolo alveolar carcinoma of the lung

Yano, T., Yokoyama, H., Fukuyama, Y., Takaai, E., Tanaka, Y., Miyagi, J., Kuninaka, S., Asoh, H. & Ichinose, Y., 1997 1月 1, In: Biotherapy. 11, 3, p. 321-323 3 p.

研究成果: Article › 査読

Mart1 is located on mouse Chromosome 19 and is excluded as a candidate for ep and ru

Wright, A., Kawakami, Y. & Pavan, W., 1997 5月 1, In: Mammalian Genome. 8, 5, p. 377-378 2 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Production of recombinant MART-1 proteins and specific anti-MART-1 polyclonal and monoclonal antibodies: Use in the characterization of the human melanoma antigen MART-1

Kawakami, Y., Battles, J. K., Kobayashi, T., Ennis, W., Wang, X., Tupesis, J. P., Marincola, F. M., Robbins, P. F., Hearing, V. J., Gonda, M. A. & Rosenberg, S. A., 1997 3月 10, In: Journal of Immunological Methods. 202, 1, p. 13-25 13 p.

研究成果: Article › 査読

92 被引用数 (Scopus)

The Intronic Region of an Incompletely Spliced gp100 Gene Transcript Encodes an Epitope Recognized by Melanoma-Reactive Tumor-Infiltrating Lymphocytes

Robbins, P. F., El-Gamil, M., Li, Y. F., Fitzgerald, E. B., Kawakami, Y. & Rosenberg, S. A., 1997 12月 1, In: Journal of Immunology. 159, 1, p. 303-308 6 p.

研究成果: Article › 査読

106 被引用数 (Scopus)

1996

Analysis of expression of the melanoma-associated antigens MART-1 and gp 100 in metastatic melanoma cell lines and in in situ lesions

Marincola, F. M., Hijazi, Y. M., Fetsch, P., Salgaller, M. L., Rivoltini, L., Cormier, J., Simonis, T. B., Duray, P. H., Herlyn, M., Kawakami, Y. & Rosenberg, S. A., 1996 1月 1, In: Journal of Immunotherapy. 19, 3, p. 192-205 14 p.

研究成果: Article › 査読

130 被引用数 (Scopus)

Antigen-specific tumor vaccines: Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy

Zhai, Y., Yang, J. C., Kawakami, Y., Spiess, P., Wadsworth, S. C., Cardoza, L. M., Couture, L. A., Smith, A. E. & Rosenberg, S. A., 1996 1月 15, In: Journal of Immunology. 156, 2, p. 700-710 11 p.

研究成果: Article › 査読

174 被引用数 (Scopus)

Human tumor antigens recognized by T cells

Robbins, P. F. & Kawakami, Y., 1996 10月, In: Current Opinion in Immunology. 8, 5, p. 628-636 9 p.

研究成果: Article › 査読

194 被引用数 (Scopus)

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