坂口光洋記念講座

研究成果

2004

Activated protein C induces endothelial cell proliferation by mitogen-activated protein kinase activation in vitro and angiogenesis in vivo

Uchiba, M., Okajima, K., Oike, Y., Ito, Y., Fukudome, K., Isobe, H. & Suda, T., 2004 7 9, : : Circulation research. 95, 1, p. 34-41 8 p.

研究成果: Article

121 引用 (Scopus)

A finger sweat chloride test for the detection of a high-risk group of chronic pancreatitis

Naruse, S., Ishiguro, H., Suzuki, Y., Fujiki, K., Ko, S. B. H., Mizuno, N., Takemura, T., Yamamoto, A., Yoshikawa, T., Jin, C., Suzuki, R., Kitagawa, M., Tsuda, T., Kondo, T. & Hayakawa, T., 2004 3, : : Pancreas. 28, 3, p. e80-e85

研究成果: Article

14 引用 (Scopus)

Angiopoietin-related/angiopoietin-like proteins regulate angiogenesis

Oike, Y., Yasunaga, K. & Suda, T., 2004 7 1, : : International journal of hematology. 80, 1, p. 21-28 8 p.

研究成果: Review article

95 引用 (Scopus)

Cell adhesion to ephrinb2 is induced by EphB4 independently of its kinase activity

Sakamoto, H., Zhang, X. Q., Suenobu, S., Ohbo, K., Ogawa, M. & Suda, T., 2004 8 27, : : Biochemical and Biophysical Research Communications. 321, 3, p. 681-687 7 p.

研究成果: Article

7 引用 (Scopus)

Derivation and morphological characterization of mouse spermatogonial stem cell lines

Ogawa, T., Ohmura, M., Tamura, Y., Kita, K., Ohbo, K., Suda, T. & Kubota, Y., 2004 11 1, : : Archives of Histology and Cytology. 67, 4, p. 297-306 10 p.

研究成果: Article

56 引用 (Scopus)

Dynamic control of cystic fibrosis transmembrane conductance regulator Cl-/HCO3- selectivity by external Cl -

Shcheynikov, N., Kim, K. H., Kim, K. M., Dorwart, M. R., Ko, S. B. H., Goto, H., Naruse, S., Thomas, P. J. & Muallem, S., 2004 5 21, : : Journal of Biological Chemistry. 279, 21, p. 21857-21865 9 p.

研究成果: Article

82 引用 (Scopus)
21 引用 (Scopus)

Gating of CFTR by the STAS domain of SLC26 transporters

Ko, S. B. H., Zeng, W., Dorwart, M. R., Luo, X., Kim, K. H., Millen, L., Goto, H., Naruse, S., Soyombo, A., Thomas, P. J. & Muallem, S., 2004 4 1, : : Nature Cell Biology. 6, 4, p. 343-350 8 p.

研究成果: Article

329 引用 (Scopus)

Genetic evidence for CFTR dysfunction in Japanese: background for chronic pancreatitis.

Fujiki, K., Ishiguro, H., Ko, S. B., Mizuno, N., Suzuki, Y., Takemura, T., Yamamoto, A., Yoshikawa, T., Kitagawa, M., Hayakawa, T., Sakai, Y., Takayama, T., Saito, M., Kondo, T. & Naruse, S., 2004 5, : : Journal of medical genetics. 41, 5, p. e55

研究成果: Letter

公開
38 引用 (Scopus)
183 引用 (Scopus)

Human intestinal epithelial cell-derived interleukin (IL)-18, along with IL2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes

Okazawa, A., Kanai, T., Nakamaru, K., Sato, T., Inoue, N., Ogata, H., Iwao, Y., Ikeda, M., Kawamura, T., Makita, S., Uraushihara, K., Okamoto, R., Yamazaki, M., Kurimoto, M., Ishii, H., Watanabe, M. & Hibi, T., 2004 5 1, : : Clinical and Experimental Immunology. 136, 2, p. 269-276 8 p.

研究成果: Article

43 引用 (Scopus)

Hyperexpression of Inducible Costimulator and Its Contribution on Lamina Propria T Cells in Inflammatory Bowel Disease

Sato, T., Kanai, T., Watanabe, M., Sakuraba, A., Okamoto, S., Nakai, T., Okazawa, A., Inoue, N., Totsuka, T., Yamazaki, M., Kroczek, R. A., Fukushima, T., Ishii, H. & Hibi, T., 2004 3, : : Gastroenterology. 126, 3, p. 829-839 11 p.

研究成果: Article

36 引用 (Scopus)

Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development

Tsunematsu, R., Nakayama, K., Oike, Y., Nishiyama, M., Ishida, N., Hatakeyama, S., Bessho, Y., Kageyama, R., Suda, T. & Nakayama, K. I., 2004 3 5, : : Journal of Biological Chemistry. 279, 10, p. 9417-9423 7 p.

研究成果: Article

197 引用 (Scopus)

Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis

Yoshida, S., Takakura, A., Ohbo, K., Abe, K., Wakabayashi, J., Yamamoto, M., Suda, T. & Nabeshima, Y. I., 2004 5 15, : : Developmental Biology. 269, 2, p. 447-458 12 p.

研究成果: Article

201 引用 (Scopus)

Regulation of cell cycle in hematopoietic stem cells by the niche

Hirao, A., Arai, F. & Suda, T., 2004 12, : : Cell Cycle. 3, 12, p. 1481-1483 3 p.

研究成果: Short survey

公開
31 引用 (Scopus)

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

Ito, K., Hirao, A., Arai, F., Matsuoka, S., Takubo, K., Hamaguchi, I., Nomiyama, K., Hosokawa, K., Sakurada, K., Nakagata, N., Ikeda, Y., Mak, T. W. & Suda, T., 2004 10 21, : : Nature. 431, 7011, p. 997-1002 6 p.

研究成果: Article

850 引用 (Scopus)

Spatial analysis of germ stem cell development in Oct-4/EGFP transgenic mice

Ohmura, M., Yoshida, S., Ide, Y., Nagamatsu, G., Suda, T. & Ohbo, K., 2004 11 1, : : Archives of Histology and Cytology. 67, 4, p. 285-296 12 p.

研究成果: Article

60 引用 (Scopus)

T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction or Th1 mediated immunopathology in Crohn's disease

Matsuoka, K., Inoue, N., Sato, T., Okamoto, S., Hisamatsu, T., Kishi, Y., Sakuraba, A., Hitotsumatsu, O., Ogata, H., Koganei, K., Fukushima, T., Kanai, T., Watanabe, M., Ishii, H. & Hibi, T., 2004 9, : : Gut. 53, 9, p. 1303-1308 6 p.

研究成果: Article

107 引用 (Scopus)

The status, quality, and expansion of the NIH full-length cDNA project: The Mammalian Gene Collection (MGC)

Gerhard, D. S., Wagner, L., Feingold, E. A., Shenmen, C. M., Grouse, L. H., Schuler, G., Klein, S. L., Old, S., Rasooly, R., Good, P., Guyer, M., Peck, A. M., Derge, J. G., Lipman, D., Collins, F. S., Jang, W., Sherry, S., Feolo, M., Misquitta, L., Lee, E. および95人, Rotmistrovsky, K., Greenhut, S. F., Schaefer, C. F., Buetow, K. H., Bonner, T. I., Haussler, D., Kent, J., Diekhans, M., Furey, T., Brent, M., Prange, C., Schreiber, K., Shapiro, N., Bhat, N. K., Hopkins, R. F., Hsie, F., Driscoll, T., Soares, M. B., Bonaldo, M. F., Casavant, T. L., Scheetz, T. E., Brownstein, M. J., Usdin, T. B., Toshiyuki, S., Carninci, P., Piao, Y., Dudekula, D. B., Ko, M. S. H., Kawakami, K., Suzuki, Y., Sugano, S., Gruber, C. E., Smith, M. R., Simmons, B., Moore, T., Waterman, R., Johnson, S. L., Ruan, Y., Lin Wei, C., Mathavan, S., Gunaratne, P. H., Wu, J., Garcia, A. M., Hulyk, S. W., Fuh, E., Yuan, Y., Sneed, A., Kowis, C., Hodgson, A., Muzny, D. M., McPherson, J., Gibbs, R. A., Fahey, J., Helton, E., Ketteman, M., Madan, A., Rodrigues, S., Sanchez, A., Whiting, M., Madan, A., Young, A. C., Wetherby, K. D., Granite, S. J., Kwong, P. N., Brinkley, C. P., Pearson, R. L., Bouffard, G. G., Blakesly, R. W., Green, E. D., Dickson, M. C., Rodriguez, A. C., Grimwood, J., Schmutz, J., Myers, R. M., Butterfield, Y. S. N., Griffith, M., Griffith, O. L., Krzywinski, M. I., Liao, N., Morrin, R., Palmquist, D., Petrescu, A. S., Skalska, U., Smailus, D. E., Stott, J. M., Schnerch, A., Schein, J. E., Jones, S. J. M., Holt, R. A., Baross, A., Marra, M. A., Clifton, S., Makowski, K. A., Bosak, S. & Malek, J., 2004 10, : : Genome Research. 14, 10 B, p. 2121-2127 7 p.

研究成果: Article

公開
378 引用 (Scopus)

Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

Arai, F., Hirao, A., Ohmura, M., Sato, H., Matsuoka, S., Takubo, K., Ito, K., Koh, G. Y. & Suda, T., 2004 7 23, : : Cell. 118, 2, p. 149-161 13 p.

研究成果: Article

1393 引用 (Scopus)
2003

Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration

Oike, Y., Yasunaga, K., Ito, Y., Matsumoto, S. I., Maekawa, H., Morisada, T., Arai, F., Nakagata, N., Takeya, M., Masuho, Y. & Suda, T., 2003 8 5, : : Proceedings of the National Academy of Sciences of the United States of America. 100, 16, p. 9494-9499 6 p.

研究成果: Article

85 引用 (Scopus)

Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice

Takagi, H., Kanai, T., Okazawa, A., Kishi, Y., Sato, T., Takaishi, H., Inoue, N., Ogata, H., Iwao, Y., Hoshino, K., Takeda, K., Akira, S., Watanabe, M., Ishii, H. & Hibi, T., 2003 8 1, : : Scandinavian Journal of Gastroenterology. 38, 8, p. 837-844 8 p.

研究成果: Article

110 引用 (Scopus)

Defective smooth muscle development in qkl-deficient mice

Li, Z., Takakura, N., Oike, Y., Imanaka, T., Araki, K., Suda, T., Kaname, T., Kondo, T., Abe, K. & Yamamura, K. I., 2003 10 1, : : Development Growth and Differentiation. 45, 5-6, p. 449-462 14 p.

研究成果: Article

47 引用 (Scopus)

Ephrin-B2 Induces Migration of Endothelial Cells Through the Phosphatidylinositol-3 Kinase Pathway and Promotes Angiogenesis in Adult Vasculature

Maekawa, H., Oike, Y., Kanda, S., Ito, Y., Yamada, Y., Kurihara, H., Nagai, R. & Suda, T., 2003 11, : : Arteriosclerosis, Thrombosis, and Vascular Biology. 23, 11, p. 2008-2014 7 p.

研究成果: Article

66 引用 (Scopus)

Ethanol induces fluid hypersecretion from guinea-pig pancreatic duct cells

Yamamoto, A., Ishiguro, H., Ko, S. B. H., Suzuki, A., Wang, Y., Hamada, H., Mizuno, N., Kitagawa, M., Hayakawa, T. & Naruse, S., 2003 9 15, : : Journal of Physiology. 551, 3, p. 917-926 10 p.

研究成果: Article

33 引用 (Scopus)

Identification and characterization of stem cells in prepubertal spermatogenesis in mice

Ohbo, K., Yoshida, S., Ohmura, M., Ohneda, O., Ogawa, T., Tsuchiya, H., Kuwana, T., Kehler, J., Abe, K., Schöler, H. R. & Suda, T., 2003 6 1, : : Developmental Biology. 258, 1, p. 209-225 17 p.

研究成果: Article

174 引用 (Scopus)

Inhibition of Angiogenesis and Vascular Leakiness by Angiopoietin-Related Protein 4

Ito, Y., Oike, Y., Yasunaga, K., Hamada, K., Miyata, K., Matsumoto, S. I., Sugano, S., Tanihara, H., Masuho, Y. & Suda, T., 2003 10 15, : : Cancer Research. 63, 20, p. 6651-6657 7 p.

研究成果: Article

134 引用 (Scopus)

In situ-synthesized novel microarray optimized for mouse stem cell and early developmental expression profiling

Carter, M. G., Hamatani, T., Sharov, A. A., Carmack, C. E., Qian, Y., Aiba, K., Ko, N. T., Dudekula, D. B., Brzoska, P. M., Hwang, S. S. & Ko, M. S. H., 2003 5 1, : : Genome Research. 13, 5, p. 1011-1021 11 p.

研究成果: Article

93 引用 (Scopus)

Neuropilin-1 on hematopoietic cells as a source of vascular development

Yamada, Y., Oike, Y., Ogawa, H., Ito, Y., Fujisawa, H., Suda, T. & Takakura, N., 2003 3 1, : : Blood. 101, 5, p. 1801-1809 9 p.

研究成果: Article

36 引用 (Scopus)

The expression of platelet endothelial cell adhesion molecule-1 in mouse primordial germ cells during their migration and early gonadal formation

Wakayama, T., Hamada, K., Yamamoto, M., Suda, T. & Iseki, S., 2003 5 1, : : Histochemistry and Cell Biology. 119, 5, p. 355-362 8 p.

研究成果: Article

24 引用 (Scopus)

Transcriptome analysis of mouse stem cells and early embryos

Sharov, A. A., Piao, Y., Matoba, R., Dudekula, D. B., Qian, Y., VanBuren, V., Falco, G., Martin, P. R., Stagg, C. A., Bassey, U. C., Wang, Y., Carter, M. G., Hamatani, T., Aiba, K., Akutsu, H., Sharova, L., Tanaka, T. S., Kimber, W. L., Yoshikawa, T., Jaradat, S. A. および20人, Pantano, S., Nagaraja, R., Boheler, K. R., Taub, D., Hodes, R. J., Longo, D. L., Schlessinger, D., Keller, J., Klotz, E., Kelsoe, G., Umezawa, A., Vescovi, A. L., Rossant, J., Kunath, T., Hogan, B. L. M., Curci, A., D'Urso, M., Kelso, J., Hide, W. & Ko, M. S. H., 2003, : : PLoS biology. 1, 3

研究成果: Article

147 引用 (Scopus)
2002

AE4 is a DIDS-sensitive Cl-/HCO3- exchanger in the basolateral membrane of the renal CCD and the SMG duct

Ko, S. B. H., Luo, X., Hager, H., Rojek, A., Choi, J. Y., Licht, C., Suzuki, M., Muallem, S., Nielsen, S. & Ishibashi, K., 2002 10, : : American Journal of Physiology - Cell Physiology. 283, 4 52-4, p. C1206-C1218

研究成果: Article

88 引用 (Scopus)

A molecular mechanism for aberrant CFTR-dependent HCO3- transport in cystic fibrosis

Ko, S. B. H., Shcheynikov, N., Choi, J. Y., Luo, X., Ishibashi, K., Thomas, P. J., Kim, J. Y., Kim, K. H., Lee, M. G., Naruse, S. & Muallem, S., 2002 11 1, : : EMBO Journal. 21, 21, p. 5662-5672 11 p.

研究成果: Article

263 引用 (Scopus)

Aquaporins in rat pancreatic interlobular ducts

Ko, S. B. H., Naruse, S., Kitagawa, M., Ishiguro, H., Furuya, S., Mizuno, N., Wang, Y., Yoshikawa, T., Suzuki, A., Shimano, S. & Hayakawa, T., 2002, : : American Journal of Physiology - Gastrointestinal and Liver Physiology. 282, 2 45-2, p. G324-G331

研究成果: Article

43 引用 (Scopus)

A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesis

Suenobu, S., Takakura, N., Inada, T., Yamada, Y., Yuasa, H., Zhang, X. Q., Sakano, S., Oike, Y. & Suda, T., 2002 1 1, : : Biochemical and Biophysical Research Communications. 293, 3, p. 1124-1131 8 p.

研究成果: Article

47 引用 (Scopus)

Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set

VanBuren, V., Piao, Y., Dudekula, D. B., Qian, Y., Carter, C. G., Martin, P. R., Stagg, C. A., Bassey, U. C., Aiba, K., Hamatani, T., Kargul, G. J., Luo, A. G., Kelso, J., Hide, W. & Ko, M. S. H., 2002 12 1, : : Genome Research. 12, 12, p. 1999-2003 5 p.

研究成果: Review article

41 引用 (Scopus)

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

Hirao, A., Cheung, A., Duncan, G., Girard, P. M., Elia, A. J., Wakeham, A., Okada, H., Sarkissian, T., Wong, J. A., Sakai, T., De Stanchina, E., Bristow, R. G., Suda, T., Lowe, S. W., Jeggo, P. A., Elledge, S. J. & Mak, T. W., 2002 9 1, : : Molecular and cellular biology. 22, 18, p. 6521-6532 12 p.

研究成果: Article

297 引用 (Scopus)

Differentiation of trophoblast lineage is associated with DNA methylation and demethylation

Ohgane, J., Hattori, N., Oda, M., Tanaka, S. & Shiota, K., 2002 1 18, : : Biochemical and Biophysical Research Communications. 290, 2, p. 701-706 6 p.

研究成果: Article

39 引用 (Scopus)

Effect of direct angiogenesis inhibition in rheumatoid arthritis using a soluble vascular endothelial growth factor receptor 1 chimeric protein

Sekimoto, T., Hamada, K., Oike, Y., Matsuoka, T., Matsumoto, M., Chosa, E., Suda, T., Tajima, N. & Yamamura, K. I., 2002 2 12, : : Journal of Rheumatology. 29, 2, p. 240-245 6 p.

研究成果: Article

23 引用 (Scopus)

Expression and function of NJ-1 surface antigen in megakaryopoiesis

Tang, H., Zhang, X. Q., Naruse, T., Ohbo, K. & Suda, T., 2002 1 1, : : Biochemical and Biophysical Research Communications. 292, 3, p. 667-674 8 p.

研究成果: Article

Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells

Burger, P. E., Coetzee, S., McKeehan, W. L., Kan, M., Cook, P., Fan, Y., Suda, T., Hebbel, R. P., Novitzky, N., Muller, W. A. & Lynette Wilson, E., 2002 11 15, : : Blood. 100, 10, p. 3527-3535 9 p.

研究成果: Article

85 引用 (Scopus)

Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity

Tanaka, T. S., Kunath, T., Kimber, W. L., Jaradat, S. A., Stagg, C. A., Usuda, M., Yokota, T., Niwa, H., Rossant, J. & Ko, M. S. H., 2002 12 1, : : Genome Research. 12, 12, p. 1921-1928 8 p.

研究成果: Review article

192 引用 (Scopus)

Mesenchymal stem cells in perichondrium express activated leukocyte cell adhesion molecule and participate in bone marrow formation

Arai, F., Ohneda, O., Miyamoto, T., Zhang, X. Q. & Suda, T., 2002 6 17, : : Journal of Experimental Medicine. 195, 12, p. 1549-1563 15 p.

研究成果: Article

173 引用 (Scopus)

Redistribution of ERK/MAP kinase to uropod-like structures in interleukin-3-induced cell shape changes

Mera, A., Suga, M., Nakayama, Y., Ando, M., Suda, T. & Yamaguchi, N., 2002 11 1, : : Immunology Letters. 84, 2, p. 117-124 8 p.

研究成果: Article

5 引用 (Scopus)

Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells

Oike, Y., Ito, Y., Hamada, K., Zhang, X. Q., Miyata, K., Arai, F., Inada, T., Araki, K., Nakagata, N., Takeya, M., Kisanuki, Y. Y., Yanagisawa, M., Gale, N. W. & Suda, T., 2002 8 15, : : Blood. 100, 4, p. 1326-1333 8 p.

研究成果: Article

公開
103 引用 (Scopus)
2001

5-Hydroxytryptamine strongly inhibits fluid secretion in guinea pig pancreatic duct cells

Suzuki, A., Naruse, S., Kitagawa, M., Ishiguro, H., Yoshikawa, T., Ko, S. B. H., Yamamoto, A., Hamada, H. & Hayakawa, T., 2001, : : Journal of Clinical Investigation. 108, 5, p. 749-756 8 p.

研究成果: Article

公開
45 引用 (Scopus)

A murine dopamine neuron-specific cDNA library and microarray: Increased COX1 expression during methamphetamine neurotoxicity

Barrett, T., Xie, T., Piao, Y., Dillon-Carter, O., Kargul, G. J., Lim, M. K., Chrest, F. J., Wersto, R., Rowley, D. L., Juhaszova, M., Zhou, L., Vawter, M. P., Becker, K. G., Cheadle, C., Wood, W. H., McCann, U. D., Freed, W. J., Ko, M. S., Ricaurte, G. A. & Donovan, D. M., 2001, : : Neurobiology of Disease. 8, 5, p. 822-833 12 p.

研究成果: Article

29 引用 (Scopus)
21 引用 (Scopus)

Endomucin is expressed in embryonic dorsal aorta and is able to inhibit cell adhesion

Ueno, M., Igarashi, K., Kimura, N., Okita, K., Takizawa, M., Nobuhisa, I., Kojima, T., Kitamura, T., Samulowitz, U., Vestweber, D., Shimomura, T., Suda, T., Nakashima, K. & Taga, T., 2001 9 21, : : Biochemical and Biophysical Research Communications. 287, 2, p. 501-506 6 p.

研究成果: Article

7 引用 (Scopus)

Exogenous clustered neuropilin 1 enhances vasculogenesis and angiogenesis

Yamada, Y., Takakura, N., Yasue, H., Ogawa, H., Fujisawa, H. & Suda, T., 2001 3 15, : : Blood. 97, 6, p. 1671-1678 8 p.

研究成果: Article

56 引用 (Scopus)