総合医科学研究センター

研究成果

2020

Factors influencing vehicle passenger fatality have changed over 10 years: a nationwide hospital-based study

Ishii, W., Hitosugi, M., Takeda, A., Baba, M. & Iizuka, R., 2020 12 1, : : Scientific reports. 10, 1, 3316.

研究成果: Article

公開

Transient appearance of Ca2+-permeable AMPA receptors is crucial for the production of repetitive LTP-induced synaptic enhancement (RISE) in cultured hippocampal slices

Tominaga-Yoshino, K., Urakubo, T., Ueno, Y., Kawaai, K., Saito, S., Tashiro, T. & Ogura, A., 2020 7 1, : : Hippocampus. 30, 7, p. 763-769 7 p.

研究成果: Article

2019
公開
1 引用 (Scopus)

Innervation of the tibial epiphysis through the intercondylar foramen

Matsuo, K., Ji, S., Miya, A., Yoda, M., Hamada, Y., Tanaka, T., Takao-Kawabata, R., Kawaai, K., Kuroda, Y. & Shibata, S., 2019 3 1, : : Bone. 120, p. 297-304 8 p.

研究成果: Article

4 引用 (Scopus)
公開
1 引用 (Scopus)
2018

Granulocyte-colony stimulating factor enhances load-induced muscle hypertrophy in mice

Ohashi, M., Okubo, K., Mizuno, S., Yoda, M., Shirasawa, H., Chiba, K., Horiuchi, K., Matsumoto, M. & Nakamura, M., 2018 1 1, (Accepted/In press) : : Biochemical and Biophysical Research Communications.

研究成果: Article

Inhibition of ADAM10 in satellite cells accelerates muscle regeneration following muscle injury

Mizuno, S., Yoda, M., Shimoda, M., Chiba, K., Nakamura, M. & Horiuchi, K., 2018 1 1, (Accepted/In press) : : Journal of Orthopaedic Research.

研究成果: Article

Targeted ablation of p38α MAPK suppresses denervation-induced muscle atrophy

Yuasa, K., Okubo, K., Yoda, M., Otsu, K., Ishii, Y., Nakamura, M., Itoh, Y. & Horiuchi, K., 2018 12 1, : : Scientific reports. 8, 1, 9037.

研究成果: Article

4 引用 (Scopus)
2017

Inhibition of PDGFR signaling prevents muscular fatty infiltration after rotator cuff tear in mice

Shirasawa, H., Matsumura, N., Shimoda, M., Oki, S., Yoda, M., Tohmonda, T., Kanai, Y., Matsumoto, M., Nakamura, M. & Horiuchi, K., 2017 1 31, : : Scientific Reports. 7, 41552.

研究成果: Article

10 引用 (Scopus)

Splicing variation of Long-IRBIT determines the target selectivity of IRBIT family proteins

Kawaai, K., Ando, H., Satoh, N., Yamada, H., Ogawa, N., Hirose, M., Mizutani, A., Bonneau, B., Seki, G. & Mikoshiba, K., 2017 4 11, : : Proceedings of the National Academy of Sciences of the United States of America. 114, 15, p. 3921-3926 6 p.

研究成果: Article

公開
7 引用 (Scopus)
2016
3 引用 (Scopus)
2015

ADAM17 regulates IL-1 signaling by selectively releasing IL-1 receptor type 2 from the cell surface

Uchikawa, S., Yoda, M., Tohmonda, T., Kanaji, A., Matsumoto, M., Toyama, Y. & Horiuchi, K., 2015 2 1, : : Cytokine. 71, 2, p. 238-245 8 p.

研究成果: Article

15 引用 (Scopus)

A disintegrin and metalloprotease 10 (ADAM10) is indispensable for maintenance of the muscle satellite cell pool

Mizuno, S., Yoda, M., Shimoda, M., Tohmonda, T., Okada, Y., Toyama, Y., Takeda, SI., Nakamura, M., Matsumoto, M. & Horiuchi, K., 2015 11 20, : : Journal of Biological Chemistry. 290, 47, p. 28456-28464 9 p.

研究成果: Article

9 引用 (Scopus)

Generation and characterization of a novel shoulder contracture mouse model

Oki, S., Shirasawa, H., Yoda, M., Matsumura, N., Tohmonda, T., Yuasa, K., Nakamura, M., Matsumoto, M. & Horiuchi, K., 2015 11 1, : : Journal of Orthopaedic Research. 33, 11, p. 1732-1738 7 p.

研究成果: Article

3 引用 (Scopus)

IRBIT regulates CaMKIIα activity and contributes to catecholamine homeostasis through tyrosine hydroxylase phosphorylation

Kawaai, K., Mizutani, A., Shoji, H., Ogawa, N., Ebisui, E., Kuroda, Y., Wakana, S., Miyakawa, T., Hisatsune, C. & Mikoshiba, K., 2015 4 28, : : Proceedings of the National Academy of Sciences of the United States of America. 112, 17, p. 5515-5520 6 p.

研究成果: Article

21 引用 (Scopus)

IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis

Tohmonda, T., Yoda, M., Iwawaki, T., Matsumoto, M., Nakamura, M., Mikoshiba, K., Toyama, Y. & Horiuchi, K., 2015 8 3, : : Journal of Clinical Investigation. 125, 8, p. 3269-3279 11 p.

研究成果: Article

19 引用 (Scopus)
2013

Conditional Inactivation of TNFα-Converting Enzyme in Chondrocytes Results in an Elongated Growth Plate and Shorter Long Bones

Saito, K., Horiuchi, K., Kimura, T., Mizuno, S., Yoda, M., Morioka, H., Akiyama, H., Threadgill, D., Okada, Y., Toyama, Y. & Sato, K., 2013 1 18, : : PloS one. 8, 1, e54853.

研究成果: Article

13 引用 (Scopus)

Systemic Overexpression of TNFα-converting Enzyme Does Not Lead to Enhanced Shedding Activity In Vivo

Yoda, M., Kimura, T., Tohmonda, T., Morioka, H., Matsumoto, M., Okada, Y., Toyama, Y. & Horiuchi, K., 2013 1 14, : : PloS one. 8, 1, e54412.

研究成果: Article

26 引用 (Scopus)

The IRE1α-XBP1 pathway positively regulates parathyroid hormone (PTH)/PTH-related peptide receptor expression and is involved in PTH-induced osteoclastogenesis

Tohmonda, T., Yoda, M., Mizuochi, H., Morioka, H., Matsumoto, M., Urano, F., Toyama, Y. & Horiuchi, K., 2013 1 18, : : Journal of Biological Chemistry. 288, 3, p. 1691-1695 5 p.

研究成果: Article

11 引用 (Scopus)
2012

A novel multi-kinase inhibitor pazopanib suppresses growth of synovial sarcoma cells through inhibition of the PI3K-AKT pathway

Hosaka, S., Horiuchi, K., Yoda, M., Nakayama, R., Tohmonda, T., Susa, M., Nakamura, M., Chiba, K., Toyama, Y. & Morioka, H., 2012 9 1, : : Journal of Orthopaedic Research. 30, 9, p. 1493-1498 6 p.

研究成果: Article

24 引用 (Scopus)

The transient appearance of zipper-like actin superstructures during the fusion of osteoclasts

Takito, J., Nakamura, M., Yoda, M., Tohmonda, T., Uchikawa, S., Horiuchi, K., Toyama, Y. & Chiba, K., 2012 2 1, : : Journal of Cell Science. 125, 3, p. 662-672 11 p.

研究成果: Article

24 引用 (Scopus)
2011

Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis

Yoda, M., Kimura, T., Tohmonda, T., Uchikawa, S., Koba, T., Takito, J., Morioka, H., Matsumoto, M., Link, D. C., Chiba, K., Okada, Y., Toyama, Y. & Horiuchi, K., 2011 12 22, : : Blood. 118, 26, p. 6939-6942 4 p.

研究成果: Article

31 引用 (Scopus)

The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix

Tohmonda, T., Miyauchi, Y., Ghosh, R., Yoda, M., Uchikawa, S., Takito, J., Morioka, H., Nakamura, M., Iwawaki, T., Chiba, K., Toyama, Y., Urano, F. & Horiuchi, K., 2011 5 1, : : EMBO Reports. 12, 5, p. 451-457 7 p.

研究成果: Article

69 引用 (Scopus)
2010

GRIP1 enhances estrogen receptor α-dependent extracellular matrix gene expression in chondrogenic cells

Kato, M., Takaishi, H., Yoda, M., Tohmonda, T., Takito, J., Fujita, N., Hosogane, N., Horiuchi, K., Kimura, T., Okada, Y., Saito, T., Kawaguchi, H., Kikuchi, T., Matsumoto, M., Toyama, Y. & Chiba, K., 2010 7 1, : : Osteoarthritis and Cartilage. 18, 7, p. 934-941 8 p.

研究成果: Article

14 引用 (Scopus)

Inhibition of STAT1 accelerates bone fracture healing

Tajima, K., Takaishi, H., Takito, J., Tohmonda, T., Yoda, M., Ota, N., Kosaki, N., Matsumoto, M., Ikegami, H., Nakamura, T., Kimura, T., Okada, Y., Horiuchi, K., Chiba, K. & Toyama, Y., 2010 7 1, : : Journal of Orthopaedic Research. 28, 7, p. 937-941 5 p.

研究成果: Article

33 引用 (Scopus)

Receptor activator of NF-κB (RANK) ligand induces ectodomain shedding of RANK in murine RAW264.7 macrophages

Hakozaki, A., Yoda, M., Tohmonda, T., Furukawa, M., Hikata, T., Uchikawa, S., Takaishi, H., Matsumoto, M., Chiba, K., Horiuchi, K. & Toyama, Y., 2010 3 1, : : Journal of Immunology. 184, 5, p. 2442-2448 7 p.

研究成果: Article

13 引用 (Scopus)
2009

Accelerated cartilage resorption by chondroclasts during bone fracture healing in osteoprotegerin-deficient mice

Ota, N., Takaishi, H., Kosaki, N., Takito, J., Yoda, M., Tohmonda, T., Kimura, T., Okada, Y., Yasuda, H., Kawaguchi, H., Matsumoto, M., Chiba, K., Ikegami, H. & Toyama, Y., 2009 11, : : Endocrinology. 150, 11, p. 4823-4834 12 p.

研究成果: Article

28 引用 (Scopus)

IL-27 abrogates receptor activator of NF-κB ligand-mediated osteoclastogenesis of human granulocyte-macrophage colony-forming unit cells through STAT1-dependent inhibition of c-Fos

Furukawa, M., Takaishi, H., Takito, J., Yoda, M., Sakai, S., Hikata, T., Hakozaki, A., Uchikawa, S., Matsumoto, M., Chiba, K., Kimura, T., Okada, Y., Matsuo, K., Yoshida, H. & Toyama, Y., 2009 8 15, : : Journal of Immunology. 183, 4, p. 2397-2406 10 p.

研究成果: Article

42 引用 (Scopus)
2006

Differences in integrin-dependent phagocytosis among three hemocyte subpopulations of the Pacific oyster "Crassostrea gigas"

Terahara, K., Takahashi, K. G., Nakamura, A., Osada, M., Yoda, M., Hiroi, T., Hirasawa, M. & Mori, K., 2006 4 25, : : Developmental and Comparative Immunology. 30, 8, p. 667-683 17 p.

研究成果: Article

46 引用 (Scopus)
2002

Detection of stimulants from charred bodies killed by a traffic accident: Distribution in the bodies

Nakajima, R., Shinozuka, T., Takei, S., Ohue, O., Baba, M., Ro, A., Yanagida, J. & Murai, T., 2002 1 1, : : Japanese Journal of Forensic Toxicology. 20, 1, p. 49-55 7 p.

研究成果: Article

Telomerase activity detected in eyed embryos of rainbow trout Oncorhynchus mykiss

Yoda, M., Takahashi, K. G. & Mori, K., 2002 3 20, : : Fisheries Science. 68, 1, p. 132-137 6 p.

研究成果: Article

4 引用 (Scopus)
2001

Sudden death due to cardiovascular disorders: A review of the studies on the medico-legal cases in Tokyo

Murai, T., Baba, M., Ro, A., Murai, N., Matsuo, Y., Takada, A. & Saito, K., 2001 9, : : Keio Journal of Medicine. 50, 3, p. 175-181 7 p.

研究成果: Review article

公開
36 引用 (Scopus)