研究成果

2020

A case of intrahepatic cholangiocellular carcinoma due to thorotrast deposition, well-controlled by radiofrequency ablation therapy

Taniki, N., Nakamoto, N., Yoshida, A., Chu, P. S., Ikura, A., Yamataka, K., Morikawa, R., Shiba, S., Yamaguchi, A., Usui, S., Ojiro, K., Ebinuma, H., Saito, H., Kubota, N., Masugi, Y., Sakamto, M. & Kanai, T., 2020 1 1, : : Acta Hepatologica Japonica. 61, 5, p. 262-269 8 p.

研究成果: Article

公開

A Nationwide, Multicenter Registry Study of Antiemesis for Carboplatin-Based Chemotherapy-Induced Nausea and Vomiting in Japan

Iihara, H., Shimokawa, M., Hayashi, T., Kawazoe, H., Saeki, T., Aiba, K. & Tamura, K., 2020 2 1, : : Oncologist. 25, 2, p. e373-e380

研究成果: Article

公開
1 引用 (Scopus)

A prospective trial of vaccine to prevent hepatitis B virus reactivation after hematopoietic stem cell transplantation

Nishikawa, K., Kimura, K., Kanda, Y., Sugiyama, M., Kakihana, K., Doki, N., Ohashi, K., Kwan Bae, S., Takahashi, K., Ishihara, Y., Mizuno, I., Onishi, Y., Onozawa, M., Onizuka, M., Yamamoto, M., Ishikawa, T., Inoue, K., Kusumoto, S., Hashino, S., Saito, H. および3人, Kanto, T., Sakamaki, H. & Mizokami, M., 2020 1 1, (Accepted/In press) : : Bone Marrow Transplantation.

研究成果: Article

公開

Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model

Abe, Y., Ikegawa, N., Yoshida, K., Muramatsu, K., Hattori, S., Kawai, K., Murakami, M., Tanaka, T., Goda, W., Goto, M., Yamamoto, T., Hashimoto, T., Yamada, K., Shibata, T., Misawa, H., Mimura, M., Tanaka, K. F., Miyakawa, T., Iwatsubo, T., Hata, J. I. および2人, Niikura, T. & Yasui, M., 2020 5 12, : : Acta Neuropathologica Communications. 8, 1, 67.

研究成果: Article

公開

Carbon monoxide rescues the developmental lethality of experimental rat models of rhabdomyolysis-induced acute kidney injury

Taguchi, K., Ogaki, S., Nagasaki, T., Yanagisawa, H., Nishida, K., Maeda, H., Enoki, Y., Matsumoto, K., Sekijima, H., Ooi, K., Ishima, Y., Watanabe, H., Fukagawa, M., Otagiri, M. & Maruyama, T., 2020 3, : : Journal of Pharmacology and Experimental Therapeutics. 372, 3, p. 355-365 11 p.

研究成果: Article

Clinical implications with tolvaptan on monitored bioimpedance-defined fluid status in patients with cirrhotic ascites: An observational study

Shiba, S., Chu, P. S., Nakamoto, N., Yamataka, K., Taniki, N., Ojiro, K., Yamaguchi, A., Morikawa, R., Yoshida, A., Ikura, A., Ebinuma, H., Saito, H. & Kanai, T., 2020 3 5, : : BMC Gastroenterology. 20, 1, 53.

研究成果: Article

公開

Commensal-bacteria-derived butyrate promotes the t-cell-independent iga response in the colon

Isobe, J., Maeda, S., Obata, Y., Iizuka, K., Nakamura, Y., Fujimura, Y., Kimizuka, T., Hattori, K., Kim, Y. G., Morita, T., Kimura, I., Offermanns, S., Adachi, T., Nakao, A., Kiyono, H., Takahashi, D. & Hase, K., 2020 4 1, : : International immunology. 32, 4, p. 243-258 16 p.

研究成果: Article

1 引用 (Scopus)

Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to Placenta-to-Maternal Hormone Signaling and Labor Induction

Inagaki, M., Nishimura, T., Nakanishi, T., Shimada, H., Noguchi, S., Akanuma, S. I., Tachikawa, M., Hosoya, K. I., Tamai, I., Nakashima, E. & Tomi, M., 2020 5 22, : : iScience. 23, 5, 101098.

研究成果: Article

公開

Cysteinyl leukotriene metabolism of human eosinophils in allergic disease

Miyata, J., Fukunaga, K., Kawashima, Y., Ohara, O. & Arita, M., 2020 1, : : Allergology International. 69, 1, p. 28-34 7 p.

研究成果: Review article

公開
2 引用 (Scopus)
1 引用 (Scopus)

Development of sustained-release ophthalmic formulation based on tranilast solid nanoparticles

Minami, M., Seiriki, R., Otake, H., Nakazawa, Y., Kanai, K., Tanino, T. & Nagai, N., 2020 4 1, : : Materials. 13, 7, 1675.

研究成果: Article

公開

Discrimination of prediction models between cold-heat and deficiency-excess patterns

Maeda-Minami, A., Yoshino, T., Katayama, K., Horiba, Y., Hikiami, H., Shimada, Y., Namiki, T., Tahara, E., Minamizawa, K., Muramatsu, S., Yamaguchi, R., Imoto, S., Miyano, S., Mima, H., Mimura, M., Nakamura, T. & Watanabe, K., 2020 3, : : Complementary Therapies in Medicine. 49, 102353.

研究成果: Article

Echinocandins versus non-echinocandins for empirical antifungal therapy in patients with hematological disease with febrile neutropenia: A systematic review and meta-analysis

Yamashita, C., Takesue, Y., Matsumoto, K., Ikegame, K., Enoki, Y., Uchino, M., Miyazaki, T., Izumikawa, K., Takada, T., Okinaka, K., Ueda, T., Miyazaki, Y. & Mayumi, T., 2020 6, : : Journal of Infection and Chemotherapy. 26, 6, p. 596-603 8 p.

研究成果: Article

公開

Effects of arterial hemorrhage speed on the blood coagulation/fibrinolysis system and hemodynamics in rats

Furukawa, S., Sasao, A., Yonemitsu, K., Ohtsu, Y., Tsutsumi, H., Taguchi, K., Otagiri, M. & Nishitani, Y., 2020 4 1, : : Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 31, 3, p. 198-206 9 p.

研究成果: Article

Evasion of the accelerated blood clearance phenomenon by polysarcosine coating of liposomes

Son, K., Ueda, M., Taguchi, K., Maruyama, T., Takeoka, S. & Ito, Y., 2020 6 10, : : Journal of Controlled Release. 322, p. 209-216 8 p.

研究成果: Article

Five new 2-(2-phenylethyl)chromone derivatives from agarwood

Shibata, S., Sugiyama, T., Uekusa, Y., Masui, R., Narukawa, Y. & Kiuchi, F., 2020 6 1, : : Journal of Natural Medicines. 74, 3, p. 561-570 10 p.

研究成果: Article

公開

Homeostatic Function of Dermokine in the Skin Barrier and Inflammation

Utsunomiya, A., Chino, T., Utsunomiya, N., Luong, V. H., Tokuriki, A., Naganuma, T., Arita, M., Higashi, K., Saito, K., Suzuki, N., Ohara, A., Sugai, M., Sugawara, K., Tsuruta, D., Oyama, N. & Hasegawa, M., 2020 4, : : Journal of Investigative Dermatology. 140, 4, p. 838-849.e9

研究成果: Article

1 引用 (Scopus)

Inhibitors of the protein–protein interaction between phosphorylated p62 and Keap1 attenuate chemoresistance in a human hepatocellular carcinoma cell line

Yasuda, D., Ohe, T., Takahashi, K., Imamura, R., Kojima, H., Okabe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Nagano, T. & Mashino, T., 2020 1 1, (Accepted/In press) : : Free Radical Research.

研究成果: Article

1 引用 (Scopus)

Kampo medicines, Rokumigan, Hachimijiogan, and Goshajinkigan, significantly inhibit glucagon-induced CREB activation

Funakoshi-Tago, M., Yu, S., Kushida, A., Takeuchi, K. & Tamura, H., 2020 3, : : Heliyon. 6, 3, e03598.

研究成果: Article

公開

LC–MS analysis of saponins of Achyranthes root in the Japanese market

Kuwada, K., Kawase, S., Nakata, K., Shinya, N., Narukawa, Y., Fuchino, H., Kawahara, N. & Kiuchi, F., 2020 1 1, : : Journal of Natural Medicines. 74, 1, p. 135-141 7 p.

研究成果: Article

Liquid Formulation of Gemcitabine Increases Venous Pain in Patients With Cancer: A Retrospective Study

Kawazoe, H., Mori, N., Ido, S., Uozumi, R., Tsuneoka, K., Takeuchi, A., Matsuo, M., Yamauchi, M., Nakai, M., Sumikawa, S., Nakamura, T. & Yakushijin, Y., 2020 4, : : Clinical Therapeutics. 42, 4, p. 712-719 8 p.

研究成果: Article

Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

Kimura, I., Miyamoto, J., Ohue-Kitano, R., Watanabe, K., Yamada, T., Onuki, M., Aoki, R., Isobe, Y., Kashihara, D., Inoue, D., Inaba, A., Takamura, Y., Taira, S., Kumaki, S., Watanabe, M., Ito, M., Nakagawa, F., Irie, J., Kakuta, H., Shinohara, M. および6人, Iwatsuki, K., Tsujimoto, G., Ohno, H., Arita, M., Itoh, H. & Hase, K., 2020 2 28, : : Science. 367, 6481, eaaw8429.

研究成果: Article

4 引用 (Scopus)

Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL-expressing plasmacytoid dendritic cells in mice

Hirata, S. I., Nagatake, T., Sawane, K., Hosomi, K., Honda, T., Ono, S., Shibuya, N., Saito, E., Adachi, J., Abe, Y., Isoyama, J., Suzuki, H., Matsunaga, A., Tomonaga, T., Kiyono, H., Kabashima, K., Arita, M. & Kunisawa, J., 2020 1 1, (Accepted/In press) : : Allergy: European Journal of Allergy and Clinical Immunology.

研究成果: Article

公開

Medications and fall risk: a case–control study in nursing home residents in Japan

Park, H., Satoh, H., Miki, A., Maki, H., Asai, K., Shiraishi, A., Urushihara, H. & Sawada, Y., 2020 5 1, : : Aging Clinical and Experimental Research. 32, 5, p. 885-892 8 p.

研究成果: Article

Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity

Nakamura, Y., Mimuro, H., Kunisawa, J., Furusawa, Y., Takahashi, D., Fujimura, Y., Kaisho, T., Kiyono, H. & Hase, K., 2020 7 1, : : Mucosal Immunology. 13, 4, p. 679-690 12 p.

研究成果: Article

1 引用 (Scopus)

Novel sustained‐release drug delivery system for dry eye therapy by rebamipide nanoparticles

Nagai, N., Ishii, M., Seiriki, R., Ogata, F., Otake, H., Nakazawa, Y., Okamoto, N., Kanai, K. & Kawasaki, N., 2020 2, : : Pharmaceutics. 12, 2, 155.

研究成果: Article

公開
2 引用 (Scopus)

Of infliximab with long-term administration in Japanese patients with Crohn's disease: Analysis using population pharmacokinetics

Matsuoka, K., Hamada, S., Shimizu, M., Nanki, K., Mizuno, S., Kiyohara, H., Arai, M., Sugimoto, S., Iwao, Y., Ogata, H., Hisamatsu, T., Nagauma, M., Kanai, T., Mochizuki, M. & Hashiguchi, M., 2020 1 1, : : International journal of clinical pharmacology and therapeutics. 58, 2, p. 89-102 14 p.

研究成果: Article

Oral intake of α-glucosyl-hesperidin ameliorates selenite-induced cataract formation

Nakazawa, Y., Aoki, M., Ishiwa, S., Morishita, N., Endo, S., Nagai, N., Yamamoto, N., Funakoshi-Tago, M. & Tamura, H., 2020 1 1, : : Molecular Medicine Reports. 21, 3, p. 1258-1266 9 p.

研究成果: Article

公開

Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity

Kimura, S., Nakamura, Y., Kobayashi, N., Shiroguchi, K., Kawakami, E., Mutoh, M., Takahashi-Iwanaga, H., Yamada, T., Hisamoto, M., Nakamura, M., Udagawa, N., Sato, S., Kaisho, T., Iwanaga, T. & Hase, K., 2020 12 1, : : Nature communications. 11, 1, 234.

研究成果: Article

公開
1 引用 (Scopus)
公開

pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2

Morita, T., Akiyoshi, T., Sato, R., Katayama, K., Yajima, K., Kataoka, H., Imaoka, A., Sugimoto, Y. & Ohtani, H., 2020 4, : : Drug Metabolism And Pharmacokinetics. 35, 2, p. 220-227 8 p.

研究成果: Article

Preface

Takada, T. & Nishimura, T., 2020 2, : : Drug Metabolism And Pharmacokinetics. 35, 1, 1 p.

研究成果: Editorial

公開

Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity

Yamasaki, K., Iohara, D., Oyama, Y., Nishizaki, N., Kawazu, S., Nishi, K., Kadowaki, D., Taguchi, K., Otagiri, M. & Seo, H., 2020 3 1, : : Journal of Pharmacy and Pharmacology. 72, 3, p. 356-363 8 p.

研究成果: Article

Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2

Funakoshi-Tago, M., Nonaka, Y., Tago, K., Takeda, M., Ishihara, Y., Sakai, A., Matsutaka, M., Kobata, K. & Tamura, H., 2020 12 1, : : Scientific reports. 10, 1, 2584.

研究成果: Article

公開
1 引用 (Scopus)

SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells

Xu, S. W., Law, B. Y. K., Qu, S. L. Q., Hamdoun, S., Chen, J., Zhang, W., Guo, J. R., Wu, A. G., Mok, S. W. F., Zhang, D. W., Xia, C., Sugimoto, Y., Efferth, T., Liu, L. & Wong, V. K. W., 2020 3, : : Pharmacological Research. 153, 104660.

研究成果: Article

2 引用 (Scopus)
公開

Strategy of drug development based on the bioactive gas-carrying capacity of hemoglobin

Taguchi, K., Matsumoto, K., Maruyama, T. & Otagiri, M., 2020 2 1, : : Yakugaku Zasshi. 140, 2, p. 141-146 6 p.

研究成果: Review article

公開
公開

Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine

Tateishi, Y., Ohe, T., Yasuda, D., Takahashi, K., Nakamura, S., Kazuki, Y. & Mashino, T., 2020 4, : : Drug Metabolism And Pharmacokinetics. 35, 2, p. 238-243 6 p.

研究成果: Article