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Article

Synthesis of 1H-2-Benzopyran-5,8-dione Skeleton through a Cascade Reaction between Benzoquinone and β-Ketoester

Nakahara, M., Ohtsu, H., Kawano, M., Hanaya, K., Sugai, T. & Higashibayashi, S., 2022 4月, In: Chemistry Letters. 51, 4, p. 356-359 4 p.

研究成果: Article › 査読

Synthesis of 3β-tert-Butyldimethylsiloxy-22-phenylthio-23,24-bisnorchola-5,9(11)-diene and Reductive Nucleophilic Attack on a Branched Aliphatic Aldehyde

Nagai, T., Hanaya, K., Higashibayashi, S., Shoji, M. & Sugai, T., 2018, In: Chemical and Pharmaceutical Bulletin. 66, 3, p. 334-338 5 p.

研究成果: Article › 査読

Open Access

Synthesis of 5-Hydroxy-3′,4′,7-trimethoxyflavone and Related Compounds and Elucidation of Their Reversal Effects on BCRP/ABCG2-Mediated Anticancer Drug Resistance

Tsunekawa, R., Katayama, K., Hanaya, K., Higashibayashi, S., Sugimoto, Y. & Sugai, T., 2019 1月 18, In: ChemBioChem. 20, 2, p. 210-220 11 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of a C₇₀ Fragment Buckybowl C₂₈H₁₄ from a C₆₀ fragment sumanene

Hishikawa, S., Okabe, Y., Tsuruoka, R., Higashibayashi, S., Ohtsu, H., Kawano, M., Yakiyama, Y. & Sakurai, H., 2017, In: Chemistry Letters. 46, 10, p. 1556-1559 4 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Synthesis of acacetin and resveratrol 3,5-di-O-β-glucopyranoside using lipase-catalyzed regioselective deacetylation of polyphenol glycoside peracetates as the key step

Hanamura, S., Hanaya, K., Shoji, M. & Sugai, T., 2016 6月 1, In: Journal of Molecular Catalysis B: Enzymatic. 128, p. 19-26 8 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Synthesis of a new glycosphingolipid, neurosporaside, from Neurospora crassa

Ohtsuka, I., Hada, N., Kanemaru, M., Fujii, T., Atsumi, T. & Kakiuchi, N., 2015 3月 2, In: Carbohydrate Research. 404, p. 9-16 8 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Synthesis of a novel glycosphingolipid from the millipede, Parafontaria laminata armigera, and the assembly of its carbohydrate moiety into multivalent structures

Hada, N., Sonoda, Y. & Takeda, T., 2006 7月 24, In: Carbohydrate Research. 341, 10, p. 1341-1352 12 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Synthesis of benzyl tetra-O-acetyl-α-L-glucopyranoside from benzyl 2,3-dideoxy-β-D-Erythro-hex-2-enopyranoside

Okazaki, H., Ueda, Y., Hanaya, K., Shoji, M. & Sugai, T., 2017, In: Heterocycles. 95, 2, p. 862-871 10 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of bioactive sesquiterpene heliannuol E involving a ring-expansion reaction of spirodienones

Doi, F., Ogamino, T., Sugai, T. & Nishiyama, S., 2003, In: Synlett. 3, p. 411-413 3 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

Synthesis of citronellyl acetate via a transacetylation to citronellol from acetyl coenzyme A produced from glucose and acetate in growing yeasts

Oda, S., Sugai, T. & Ohta, H., 2001, In: Chemistry Letters. 6, p. 500-501 2 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of enantiomerically enriched drug precursors and an insect pheromone via reduction of ketones using commercially available carbonyl reductase screening kit “Chiralscreen® OH”

Nagai, T., Sakurai, S., Natori, N., Hataoka, M., Kinoshita, T., Inoue, H., Hanaya, K., Shoji, M. & Sugai, T., 2018 4月 1, In: Bioorganic and Medicinal Chemistry. 26, 7, p. 1304-1313 10 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Synthesis of enantiomers of indanoxazolidinone based on the lipase-catalyzed resolution of the corresponding N-carbamylamino derivative

Suzuki, M., Nagasawa, C. & Sugai, T., 2001 6月 4, In: Tetrahedron. 57, 23, p. 4841-4848 8 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Synthesis of fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation

Tsunekawa, R., Hanaya, K., Higashibayashi, S. & Sugai, T., 2018, In: Bioscience, Biotechnology and Biochemistry. 82, 8, p. 1316-1322 7 p.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity

Yasuda, D., Nakajima, M., Yuasa, A., Obata, R., Takahashi, K., Ohe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Imamura, R., Kojima, H., Okabe, T., Nagano, T. & Mashino, T., 2016, In: Bioorganic and Medicinal Chemistry Letters. 26, 24, p. 5956-5959 4 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Synthesis of linezolid metabolites PNU-142300 and PNU-142586 toward the exploration of metabolite-related events

Hanaya, K., Matsumoto, K., Yokoyama, Y., Kizu, J., Shoji, M. & Sugai, T., 2017, In: Chemical and Pharmaceutical Bulletin. 65, 2, p. 194-199 6 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of methyl epi-anhydroquinate utilizing [2,3]-sigmatropic rearrangement of iodosoalkene

Inomata, S., Ueda, M., Sugai, T. & Shoji, M., 2013, In: Chemistry Letters. 42, 10, p. 1273-1275 3 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of methylophiopogonanone a

Katagiri, R., Uekusa, Y., Narukawa, Y. & Kiuchi, F., 2020, In: Heterocycles. 100, 5, p. 803-808 6 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Synthesis of methyl ursodeoxycholate via microbial reduction of methyl 7-ketolithocholate with Eubacterium aerofaciens JCM 7790 grown on two kinds of carbon and hydride sources, glucose and mannitol

Oda, S., Sugai, T. & Ohta, H., 2001 1月 1, In: Journal of Bioscience and Bioengineering. 91, 2, p. 178-183 6 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Synthesis of model compounds related to linear β-d-(1→6)-galactosyl side-chains of polysaccharides from astragalus mongholicus bunge

Hada, N., Shimura, R., Hakamata, K., Kiyohara, H., Yamada, H., Takeda, A. & Kiuchi, F., 2015, In: Heterocycles. 90, 1, p. 563-578 16 p.

研究成果: Article › 査読

Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation

Ohe, T., Umezawa, R., Kitagawara, Y., Yasuda, D., Takahashi, K., Nakamura, S., Abe, A., Sekine, S., Ito, K., Okunushi, K., Morio, H., Furihata, T., Anzai, N. & Mashino, T., 2018 12月 15, In: Bioorganic and Medicinal Chemistry Letters. 28, 23-24, p. 3708-3711 4 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Synthesis of okicamelliaside, a glucoside of ellagic acid with potent anti-degranulation activity

Kobayashi, R., Hanaya, K., Shoji, M., Ohba, S. & Sugai, T., 2013, In: Bioscience, Biotechnology and Biochemistry. 77, 4, p. 810-813 4 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Synthesis of oroxylin A starting from naturally abundant baicalin

Fujita, R., Hanaya, K., Higashibayashi, S. & Sugai, T., 2018, In: Heterocycles. 97, 2, p. 1165-1174 10 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Synthesis of Phosphatidylcholines Possessing Functionalized Acids at sn -2, and ¹³ C- ¹⁴ N and ¹³ C- ³¹ P Couplings in Their ¹³ C NMR Spectra

Morita, M., Saito, S., Shinohara, R., Aoyagi, R., Arita, M. & Kobayashi, Y., 2020 4月 22, In: Synlett. 31, 7, p. 718-722 5 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of Regioselectively Protected Forms of Cytidine Based on Enzyme-catalyzed Deacetylation as the Key Step

Kuboki, A., Ishihara, T., Kobayashi, E., Ohta, H., Ishii, T., Inoue, A., Mitsuda, S., Miyazaki, T., Kajihara, Y. & Sugai, T., 2000 1月 1, In: Bioscience, Biotechnology and Biochemistry. 64, 2, p. 363-368 6 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Synthesis of Sulfinimines by Direct Condensation of Sulfinamides with Aldehydes Using Cs₂CO₃ as an Activating and Dehydrating Reagent

Higashibayashi, S., Tohmiya, H., Mori, T., Hashimoto, K. & Nakata, M., 2004 2月 18, In: Synlett. 3, p. 457-460 4 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

Synthesis of the (4R,5R)-Isomer of 5-Hydroxy-6-phenyl-4-hexanolide, a Lateral Root-inducing Substance Isolated from Erwinia quercina

Sugai, T., Noguchi, H. & Ohta, H., 1992 1月 1, In: Bioscience, Biotechnology, and Biochemistry. 56, 1, p. 122-126 5 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Synthesis of the 1,2-seco fusicoccane diterpene skeleton by Stille coupling reaction between the highly functionalized A and C ring segments of cotylenin A

Kuwata, K., Hanaya, K., Higashibayashi, S., Sugai, T. & Shoji, M., 2017, In: Tetrahedron. 73, 41, p. 6039-6045 7 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Synthesis of the Non Reducing End Oligosaccharides of Glycosphingolipids from Ascaris suum

Hada, N., Umeda, Y., Kumada, H., Shimazaki, Y., Yamano, K., Schweizer, F., Oshima, N., Takeda, T. & Kiuchi, F., 2019, In: Chemical and Pharmaceutical Bulletin. 67, 2, p. 143-154 12 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Synthesis of trans,trans,cis-fused tetracyclic skeleton via radical domino cyclization

Furuta, M., Hanaya, K., Sugai, T. & Shoji, M., 2017, In: Tetrahedron. 73, 16, p. 2316-2322 7 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Synthesis of trilobatin from naringin via prunin as the key intermediate: Acidic hydrolysis of the α-rhamnosidic linkage in naringin under improved conditions

Kurahayashi, K., Hanaya, K., Higashibayashi, S. & Sugai, T., 2018, In: Bioscience, Biotechnology and Biochemistry. 82, 9, p. 1463-1467 5 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Synthesis of various water-soluble C₆₀ derivatives and their superoxide-quenching activity

Okuda, K., Hirota, T., Hirobe, M., Nagano, T., Mochizuki, M. & Mashino, T., 2000 1月 1, In: Fullerene Science and Technology. 8, 3, p. 127-142 16 p.

研究成果: Article › 査読

29 被引用数 (Scopus)

Synthesis of water-soluble C₆₀-porphyrin hybrid compounds

Okuda, K., Abeta, C., Hirota, T., Mochizuki, M. & Mashino, T., 2002 7月, In: Chemical and Pharmaceutical Bulletin. 50, 7, p. 985-987 3 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Synthetic Route to 2-Deoxyaldoses by Fluoride-Catalyzed Solvolysis of Enol-Phosphate Esters

Mitsuo, N., Abe, Y., Takizawa, T. & Kunieda, T., 1980, In: Chemical and Pharmaceutical Bulletin. 28, 4, p. 1327-1330 4 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Synthetic studies on an oligosaccharide of a glycolipid from the spermatozoa of bivalves IX. Syntheses of lipids I, II, and IV

Hada, N., Takeda, T. & Ogihara, Y., 1994 5月 20, In: Carbohydrate Research. 258, C, p. 93-104 12 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of amphoteric glycolipid analogues from the porcine nematode, Ascaris suum

Ohtsuka, I., Hada, N., Ohtaka, H., Sugita, M. & Takeda, T., 2002 5月, In: Chemical and Pharmaceutical Bulletin. 50, 5, p. 600-604 5 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of neogala-series glycolipid analogues containing a mannose residue from the earthworm Pheretima hilgendorfi

Hada, N., Matsusaki, A., Sugita, M. & Takeda, T., 1999 9月, In: Chemical and Pharmaceutical Bulletin. 47, 9, p. 1265-1268 4 p.

研究成果: Article › 査読

Open Access

14 被引用数 (Scopus)

Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of a glycosphingolipid analogue from the parasite Spirometra erinacei

Hada, N., Kuroda, M. & Takeda, T., 2000, In: Chemical and Pharmaceutical Bulletin. 48, 8, p. 1160-1165 6 p.

研究成果: Article › 査読

Open Access

20 被引用数 (Scopus)

Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of glycosphingolipids from the parasite Schistosoma mansoni

Kanaya, T., Yagi, S., Schweizer, F., Takeda, T., Kiuchi, F. & Hada, N., 2010 6月, In: Chemical and Pharmaceutical Bulletin. 58, 6, p. 811-817 7 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of glycosphingolipid from the marine sponge Spheciospongia vesparia and its analogue

Hada, N., Miyamura, A., Ohtsuka, I. & Kiuchi, F., 2014, In: Heterocycles. 88, 1, p. 689-704 16 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Synthetic studies on the thiostrepton family of peptide antibiotics: Synthesis of the tetrasubstituted dehydropiperidine and piperidine cores

Higashibayashi, S., Hashimoto, K. & Nakata, M., 2002 1月 1, In: Tetrahedron Letters. 43, 1, p. 105-110 6 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the pentapeptide segment containing dihydroxyisoleucine, thiazoline and dehydroamino acid

Higashibayashi, S., Kohno, M., Goto, T., Suzuki, K., Mori, T., Hashimoto, K. & Nakata, M., 2004 5月 3, In: Tetrahedron Letters. 45, 19, p. 3707-3712 6 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the tetrasubstituted dihydroquinoline portion of siomycin D₁

Higashibayashi, S., Mori, T., Shinko, K., Hashimoto, K. & Nakata, M., 2002 1月 1, In: Heterocycles. 57, 1, p. 111-122 12 p.

研究成果: Article › 査読

25 被引用数 (Scopus)

Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the cyclic core portion containing the dehydropiperidine, dihydroquinoline, L-valine, and masked dehydroalanine segments

Mori, T., Tohmiya, H., Satouchi, Y., Higashibayashi, S., Hashimoto, K. & Nakata, M., 2005 9月 19, In: Tetrahedron Letters. 46, 38, p. 6423-6427 5 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the dihydroquinoline portion of thiostrepton, the siomycins, and the thiopeptins

Mori, T., Satouchi, Y., Tohmiya, H., Higashibayashi, S., Hashimoto, K. & Nakata, M., 2005 9月 19, In: Tetrahedron Letters. 46, 38, p. 6417-6422 6 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

System A amino acid transporter SNAT2 shows subtype-specific affinity for betaine and hyperosmotic inducibility in placental trophoblasts

Nishimura, T., Yagi, R., Usuda, M., Oda, K., Yamazaki, M., Suda, S., Takahashi, Y., Okazaki, F., Sai, Y., Higuchi, K., Maruyama, T., Tomi, M. & Nakashima, E., 2014 5月, In: Biochimica et Biophysica Acta - Biomembranes. 1838, 5, p. 1306-1312 7 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Systematic approach to a dosage regimen for phenytoin based on one-point, steady-state plasma concentration

Nakashima, E., Matsushita, R., Kido, H., Nakamura, M., Asahi, M. & Ichimura, F., 1995 2月, In: Therapeutic Drug Monitoring. 17, 1, p. 12-18 7 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Systems pharmacology of adverse event mitigation by drug combinations

Zhao, S., Nishimura, T., Chen, Y., Azeloglu, E. U., Gottesman, O., Giannarelli, C., Zafar, M. U., Benard, L., Badimon, J. J., Hajjar, R. J., Goldfarb, J. & Iyengar, R., 2013 10月 9, In: Science translational medicine. 5, 206, 206ra140.

研究成果: Article › 査読

81 被引用数 (Scopus)

Tacrine Increases Stimulation-Evoked Acetylcholine Release from Rat Hippocampal Slices.

Suzuki, T., Nonaka, H., Fujimoto, K. & Kawashima, K., 1994, In: Japanese Journal of Pharmacology. 65, 4, p. 337-342 6 p.

研究成果: Article › 査読

Open Access

5 被引用数 (Scopus)

TAK1 promotes cell survival by TNFAIP3 and IL-8 dependent and NF-kB independent pathway in HeLa cells exposed to heat stress

Li, P., Furusawa, Y., Wei, Z. L., Sakurai, H., Tabuchi, Y., Zhao, Q. L., Saiki, I. & Kondo, T., 2013, In: International Journal of Hyperthermia. 29, 7, p. 688-695 8 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Tankyrase-1 assembly to large protein complexes blocks its telomeric function

Hatsugai, K., Ohishi, T., Sugimoto, Y. & Seimiya, H., 2010 9月, In: FEBS Letters. 584, 18, p. 3885-3890 6 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

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