薬学部

研究成果

年別の研究成果 1975 2009 2012 2014 2015 2016 2017 2018 2019 2020 2021 2022

• 2371 Article
• 147 Review article
• 23 Letter
• 22 Comment/debate
• 56 その他
  • 20 Editorial
  • 18 Chapter
  • 7 Paper
  • 6 Conference contribution
  • 5 Short survey

年別の研究成果

年別の研究成果

検索結果

• Article

  Anticancer Drug Prescription Patterns in Japan: Future Directions in Cancer Therapy

  Shibata, S., Matsushita, M., Saito, Y. & Suzuki, T., 2018 11月 1, In: Therapeutic Innovation and Regulatory Science. 52, 6, p. 718-723 6 p.

  研究成果: Article › 査読

  • Drug Prescriptions 100%
  • cancer 74%
  • medication 70%
  • Japan 67%
  • Direction compound 59%
  4 被引用数 (Scopus)

• Anti-c-Mpl (thrombopoietin receptor) autoantibody-induced amegakaryocytic thrombocytopenia in a patient with systemic sclerosis

  Katsumata, Y., Suzuki, T., Kuwana, M., Hattori, Y., Akizuki, S., Sugiura, H. & Matsuoka, Y., 2003 6月 1, In: Arthritis and Rheumatism. 48, 6, p. 1647-1651 5 p.

  研究成果: Article › 査読

  • Thrombopoietin Receptors 100%
  • Systemic Scleroderma 74%
  • Thrombocytopenia 61%
  • Autoantibodies 60%
  • Platelet Count 38%
  18 被引用数 (Scopus)

• Anti-complementary and hypoglycemic activities of the glycans from the seeds of Malva Verticillata

  Tomoda, M., Shimizu, N., Gonda, R., Kanari, M., Yamada, H. & Hikino, H., 1990 5月 18, In: Planta Medica. 56, 2, p. 168-170 3 p.

  研究成果: Article › 査読
  27 被引用数 (Scopus)

• Anticomplementary and hypoglycemic activity of Okra and Hibiscus mucilages

  Tomoda, M., Shimizu, N., Gonda, R., Kanari, M., Yamada, H. & Hikino, H., 1989 7月 15, In: Carbohydrate Research. 190, 2, p. 323-328 6 p.

  研究成果: Article › 査読
  31 被引用数 (Scopus)

• Anti-fibrogenic effect of an angiotensin converting enzyme inhibitor on chronic carbon tetrachloride-induced hepatic fibrosis in rats

  Ohishi, T., Saito, H., Tsusaka, K., Toda, K., Inagaki, H., Hamada, Y., Kumagai, N., Atsukawa, K. & Ishii, H., 2001, In: Hepatology Research. 21, 2, p. 147-158 12 p.

  研究成果: Article › 査読

  • Carbon Tetrachloride 100%
  • Angiotensin-Converting Enzyme Inhibitors 81%
  • Fibrosis 61%
  • Lisinopril 58%
  • Liver 42%
  74 被引用数 (Scopus)

• Antihypertensive action of melatonin in the spontaneously hypertensive rat

  Kawashima, K., Miwa, Y., Fujimoto, K., Oohata, H., Nishino, H. & Koike, H., 1987, In: Clinical and Experimental Hypertension. A9, 7, p. 1121-1131 11 p.

  研究成果: Article › 査読

  • Inbred SHR Rats 100%
  • Melatonin 99%
  • Antihypertensive Agents 84%
  • Heart Rate 22%
  • Blood Pressure 19%
  90 被引用数 (Scopus)

• Antihypertensive and diuretic effects of YM-09730-5, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats

  Kawashima, K., Toda, H., Oohata, H., Fujimoto, K., Suzuki, T. & Inagaki, O., 1991, In: General Pharmacology. 22, 2, p. 263-266 4 p.

  研究成果: Article › 査読

  • mepirodipine 100%
  • Inbred SHR Rats 57%
  • Diuretics 52%
  • Antihypertensive Agents 48%
  • Calcium 36%
  13 被引用数 (Scopus)

• Antihypertensive drug effects according to the pretreatment self-measured home blood pressure: The HOMED-BP study

  Sano, H., Hara, A., Asayama, K., Miyazaki, S., Kikuya, M., Imai, Y. & Ohkubo, T., 2020 12月 12, In: BMJ open. 10, 12, 40524.

  研究成果: Article › 査読

  Open Access

  • Antihypertensive Agents 100%
  • Blood Pressure 69%
  • Clinical Trials 10%
  • Essential Hypertension 8%
  • Reading 7%
  1 被引用数 (Scopus)

• Antihypertensive Effect of Chronic KT3-671, a Structurally New Nonpeptide Angiotensin AT₁-Receptor Antagonist, in Stroke-Prone Spontaneously Hypertensive Rats

  Amano, H., Fujimoto, K., Suzuki, T., Fujii, T., Kawashima, K., Mochizuki, S. & Tomiyama, A., 1995, In: The Japanese Journal of Pharmacology. 69, 3, p. 215-222 8 p.

  研究成果: Article › 査読

  Open Access

  • KT3 671 100%
  • Angiotensin Type 1 Receptor 54%
  • Angiotensin Receptor Antagonists 49%
  • Inbred SHR Rats 47%
  • Antihypertensive Agents 40%
  11 被引用数 (Scopus)

• Antihypertensive effect of repeatedly administered YM358, an angiotensin AT₁-receptor antagonist, in stroke-prone spontaneously hypertensive rats

  Yamaguchi, N., Fujimoto, K., Fujii, T., Suzuki, T. & Kawashima, K., 1997, In: Japanese Journal of Pharmacology. 73, 1, p. 83-91 9 p.

  研究成果: Article › 査読

  Open Access

  • YM358 100%
  • Angiotensin Type 1 Receptor 52%
  • Angiotensin Receptor Antagonists 48%
  • Inbred SHR Rats 46%
  • Antihypertensive Agents 39%
  8 被引用数 (Scopus)

• Antihypertensive effect of synthetic tetrandrine derivatives in SHR rats

  Kawashima, K., Hayakawa, T., Hisayo, O., Fujimoto, K., Suzuki, T., Ogino, T. & Chen (Masao Chin), Z., 1991, In: General Pharmacology. 22, 1, p. 165-168 4 p.

  研究成果: Article › 査読

  • tetrandrine 100%
  • Inbred SHR Rats 69%
  • Antihypertensive Agents 58%
  • Phenylephrine 46%
  • Renin 42%
  6 被引用数 (Scopus)

• Antihypertensive effect of YM730, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats

  Toda, H., Oohata, H., Fujimoto, K., Suzuki, T., Kawashima, K. & Inagaki, O., 1990, In: japanese heart journal. 31, 4, p. 542 1 p.

  研究成果: Article › 査読

  Open Access

• ANTIHYPERTENSIVE EFFECTS, DETERMINED BY A TELEMETRY METHOD, OF TRICHLOROMETHIAZIDE AND 7–O‐ETHYLFANGCHINOLINE, A DERIVATIVE OF TETRANDRINE, IN SPONTANEOUSLY HYPERTENSIVE RATS

  Kawashima, K., Negishi, T., Amano, H., Fujimoto, K., Suzuki, T. & Fujii, T., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S300-S301

  研究成果: Article › 査読

  • Trichlormethiazide 100%
  • tetrandrine 88%
  • Telemetry 72%
  • Inbred SHR Rats 61%
  • Antihypertensive Agents 51%
  3 被引用数 (Scopus)

• Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway

  Funakoshi-Tago, M., Okamoto, K., Izumi, R., Tago, K., Yanagisawa, K., Narukawa, Y., Kiuchi, F., Kasahara, T. & Tamura, H., 2015 3月, In: International Immunopharmacology. 25, 1, p. 189-198 10 p.

  研究成果: Article › 査読

  • Propolis 100%
  • Interleukin-33 97%
  • Flavonoids 72%
  • 4-methoxydalbergione 65%
  • Anti-Inflammatory Agents 52%
  61 被引用数 (Scopus)

• Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin

  Funakoshi-Tago, M., Nakamura, K., Tago, K., Mashino, T. & Kasahara, T., 2011 9月, In: International Immunopharmacology. 11, 9, p. 1150-1159 10 p.

  研究成果: Article › 査読

  • fisetin 100%
  • Apigenin 86%
  • Luteolin 86%
  • Flavonoids 62%
  • Anti-Inflammatory Agents 45%
  190 被引用数 (Scopus)

• Anti-inflammatory effects of linezolid on carrageenan-induced paw edema in rats

  Matsumoto, K., Obara, S., Kuroda, Y. & Kizu, J., 2015 12月 1, In: Journal of Infection and Chemotherapy. 21, 12, p. 889-891 3 p.

  研究成果: Article › 査読

  • Linezolid 100%
  • Carrageenan 92%
  • Edema 63%
  • Anti-Inflammatory Agents 57%
  • arbekacin 18%
  15 被引用数 (Scopus)

• Antimitotic activity and reversal of breast cancer resistance protein-mediated drug resistance by stilbenoids from Bletilla striata

  Morita, H., Koyama, K., Sugimoto, Y. & Kobayashi, J., 2005 2月 15, In: Bioorganic and Medicinal Chemistry Letters. 15, 4, p. 1051-1054 4 p.

  研究成果: Article › 査読

  • Stilbenoid 100%
  • Antimitotic 95%
  • Antimitotic Agents 92%
  • Stilbenes 91%
  • lusianthridin 73%
  60 被引用数 (Scopus)

• Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay

  Inami, K., Mine, Y., Kojo, Y., Tanaka, S., Ishikawa, S. & Mochizuki, M., 2017, In: Natural Product Research. 31, 6, p. 691-695 5 p.

  研究成果: Article › 査読

  • Glabridin 100%
  • Liquiritigenin 92%
  • Glycyrrhiza 86%
  • N-methyl-N-nitrosourea 82%
  • Methylnitrosourea 76%
  4 被引用数 (Scopus)

• Antimutagenicity screening of extracts from medicinal and edible plants against N-Methyl-N-nitrosourea by the Ames assay

  Tatsuzaki, J., Jinwei, Y., Kojo, Y., Mine, Y., Ishikawa, S., Mochizuki, M. & Inami, K., 2014, In: Genes and Environment. 36, 2, p. 39-46 8 p.

  研究成果: Article › 査読

  • Methylnitrosourea 100%
  • Glycyrrhiza 99%
  • Ginger 97%
  • Edible Plants 96%
  • medicinal plant 94%
  3 被引用数 (Scopus)

• Antioxidant activities of 5-hydroxyoxindole and its 3-hydroxy-3-phenacyl derivatives: The suppression of lipid peroxidation and intracellular oxidative stress

  Yasuda, D., Takahashi, K., Ohe, T., Nakamura, S. & Mashino, T., 2013 12月 15, In: Bioorganic and Medicinal Chemistry. 21, 24, p. 7709-7714 6 p.

  研究成果: Article › 査読

  • 5-hydroxyoxindole 100%
  • Oxindoles 49%
  • Oxidative Stress 42%
  • Lipid Peroxidation 39%
  • Antioxidant Agent 32%
  15 被引用数 (Scopus)

• Antioxidant vitamins and lysophospholipids are critical for inducing mouse spermatogenesis under organ culture conditions

  Sanjo, H., Yao, T., Katagiri, K., Sato, T., Matsumura, T., Komeya, M., Yamanaka, H., Yao, M., Matsuhisa, A., Asayama, Y., Ikeda, K., Kano, K., Aoki, J., Arita, M. & Ogawa, T., 2020 7月 1, In: FASEB Journal. 34, 7, p. 9480-9497 18 p.

  研究成果: Article › 査読

  Open Access

  • Lysophospholipids 100%
  • Organ Culture Techniques 81%
  • Spermatogenesis 75%
  • Culture Media 74%
  • Vitamin 70%
  3 被引用数 (Scopus)

• Antioxidative activity of indenestrol a, a diethylstilbestrol metabolite

  Oda, T., Ebata, M., Matsumoto, S., Urano, S. & Sato, Y., 1999 6月, In: Biological and Pharmaceutical Bulletin. 22, 6, p. 586-589 4 p.

  研究成果: Article › 査読

  Open Access

  • indenestrol 100%
  • Diethylstilbestrol 61%
  • Antioxidant Agent 33%
  • Estradiol Congeners 33%
  • Metabolite 31%
  3 被引用数 (Scopus)

• Antisense oligodeoxynucleotide against c-myc mRNA induces differentiation of human hepatocellular carcinoma cells.

  Ebinuma, H., Saito, H., Saito, Y., Wakabayashi, K., Nakamura, M., Kurose, I. & Ishii, H., 1999 11月, In: International journal of oncology. 15, 5, p. 991-999 9 p.

  研究成果: Article › 査読

  • Oligodeoxyribonucleotides 100%
  • Hepatocellular Carcinoma 66%
  • Messenger RNA 47%
  • Antigens 32%
  • Liver 26%
  19 被引用数 (Scopus)

• Anti-trypanosomal screening of Salvadoran flora

  Castillo, U. G., Komatsu, A., Martínez, M. L., Menjívar, J., Núñez, M. J., Uekusa, Y., Narukawa, Y., Kiuchi, F. & Nakajima-Shimada, J., 2022 1月, In: Journal of Natural Medicines. 76, 1, p. 259-267 9 p.

  研究成果: Article › 査読

  Open Access

  • Pinocembrin 100%
  • Piper 91%
  • Antitrypanosomal 89%
  • cardamonin 75%
  • pinocembrin 71%

• Anti-tumor promoting action of phthalic acid mono-n-butyl ester cupric salt, a biomimetic superoxide dismutase

  Yamamoto, S., Nakadate, T., Aizu, E. & Kato, R., 1990 5月, In: Carcinogenesis. 11, 5, p. 749-754 6 p.

  研究成果: Article › 査読

  • phthalic acid 100%
  • Biomimetics 92%
  • Esters 75%
  • Superoxide Dismutase 67%
  • Ornithine Decarboxylase 66%
  13 被引用数 (Scopus)

• A partial agonist for retinoid X receptor mitigates experimental colitis

  Masayoshi, O., Masaki, W., Narumi, I., Koichiro, S., Kei, T., Masato, H., Takahiro, Y., Aiko, E., Osamu, S., Midori, N., Michiko, F., Makoto, M., Daisuke, T., Yukihiro, F., Hiroki, K. & Koji, H., 2019 2月 19, In: International immunology. 31, 4, p. 251-262 12 p.

  研究成果: Article › 査読

  Open Access

  • Retinoid X Receptors 100%
  • 1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)-1H-benzotriazole-5-carboxylic acid 89%
  • Colitis 75%
  • Cytoplasmic and Nuclear Receptors 28%
  • Ulcerative Colitis 27%
  10 被引用数 (Scopus)

• A patient with genetic deletion of glutathione-S-transferase T1 and M1 who developed non-small-cell lung cancer and myelodysplastic syndromes

  Arai, Y., Hirose, N., Yamamura, K., Nagai, M., Jang, H., Hattori, Y. & Ikeda, Y., 1999 12月, In: American Journal of the Medical Sciences. 318, 6, p. 424-427 4 p.

  研究成果: Article › 査読

  • glutathione S-transferase M1 100%
  • glutathione S-transferase T1 99%
  • Myelodysplastic Syndromes 73%
  • Non-Small Cell Lung Carcinoma 58%
  • Lung Neoplasms 51%
  2 被引用数 (Scopus)

• APC mutations as a potential biomarker for sensitivity to tankyrase inhibitors in colorectal cancer

  Tanaka, N., Mashima, T., Mizutani, A., Sato, A., Aoyama, A., Gong, B., Yoshida, H., Muramatsu, Y., Nakata, K., Matsuura, M., Katayama, R., Nagayama, S., Fujita, N., Sugimoto, Y. & Seimiya, H., 2017 4月, In: Molecular cancer therapeutics. 16, 4, p. 752-762 11 p.

  研究成果: Article › 査読

  • Tankyrases 100%
  • Catenins 74%
  • Adenomatous Polyposis Coli 72%
  • Colorectal Neoplasms 46%
  • Biomarkers 38%
  51 被引用数 (Scopus)

• APC protein is required for initiation of neuronal differentiation in rat pheochromocytoma PC12 cells

  Dobashi, Y., Katayama, K., Kawai, M., Akiyama, T. & Kameya, T., 2000 12月 20, In: Biochemical and Biophysical Research Communications. 279, 2, p. 685-691 7 p.

  研究成果: Article › 査読

  • PC12 Cells 100%
  • Pheochromocytoma 97%
  • Protein 36%
  • Microtubule-Associated Proteins 34%
  • Proteins 32%
  17 被引用数 (Scopus)

• A phenylphthalimide derivative, TC11, induces apoptosis by degrading MCL1 in multiple myeloma cells

  Ichikawa, D., Nakamura, M., Murota, W., Osawa, S., Matsushita, M., Yanagawa, H. & Hattori, Y., 2020 1月 1, In: Biochemical and Biophysical Research Communications. 521, 1, p. 252-258 7 p.

  研究成果: Article › 査読

  • Multiple Myeloma 100%
  • Cytogenetics 95%
  • Apoptotic 77%
  • Apoptosis 61%
  • Lenalidomide 60%
  2 被引用数 (Scopus)

• A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myeloma

  Shiheido, H., Terada, F., Tabata, N., Hayakawa, I., Matsumura, N., Takashima, H., Ogawa, Y., Du, W., Yamada, T., Shoji, M., Sugai, T., Doi, N., Iijima, S., Hattori, Y. & Yanagawa, H., 2012 6月 25, In: PloS one. 7, 6, e38878.

  研究成果: Article › 査読

  • phthalimide 100%
  • nucleophosmin 81%
  • myeloma 69%
  • Phthalimide 68%
  • Multiple Myeloma 54%
  23 被引用数 (Scopus)

• A physiologically based pharmacokinetic model for (-)-quinuclidinyl benzylate using nonlinear irreversible tissue binding parameters in rats

  Ishizaki, J., Nakashima, E., Yokogawa, K., Nagano, T., Takayasu, T. & Ichimura, F., 1992 1月 1, In: Drug Metabolism and Disposition. 20, 4, p. 485-489 5 p.

  研究成果: Article › 査読

  • Drug Binding Parameter 100%
  • Pharmacokinetics 61%
  • Plasma 33%
  • Plasma Concentration 31%
  • Clearance 29%
  3 被引用数 (Scopus)

• A Physiologically Based Pharmacokinetic Model for Biperiden in Animals and Its Extrapolation to Humans

  Nakashima, E., Yokogawa, K., Ichimura, F., Yamana, T., Kurata, K., Kido, H. & Yamaguchi, N., 1987, In: Chemical and Pharmaceutical Bulletin. 35, 2, p. 718-725 8 p.

  研究成果: Article › 査読

  Open Access

  • Biperiden 100%
  • Clearance 54%
  • Pharmacokinetics 38%
  • Plasma Concentration 29%
  • Animals 25%
  18 被引用数 (Scopus)

• Apoptosis induced in human cell lines by a butanol extract from Chlorophytum comosum roots

  Matsushita, H., Kuwabara, H., Ishikawa, S. & Mochizuki, M., 2005, In: Journal of Health Science. 51, 3, p. 341-345 5 p.

  研究成果: Article › 査読

  • dUTP 100%
  • Butanols 88%
  • Biotin 69%
  • Antiproliferative 64%
  • Butene 62%
  8 被引用数 (Scopus)

• Apoptotic cell death by the novel natural compound, cinobufotalin

  Emam, H., Zhao, Q. L., Furusawa, Y., Refaat, A., Ahmed, K., Kadowaki, M. & Kondo, T., 2012 9月 30, In: Chemico-Biological Interactions. 199, 3, p. 154-160 7 p.

  研究成果: Article › 査読

  • cinobufotalin 100%
  • Cinobufotalin 98%
  • Apoptotic 56%
  • Cell Death 52%
  • Occurrence in Nature 40%
  27 被引用数 (Scopus)

• Apparatus for Dual-Flow Countercurrent Extraction and Its Evaluation

  Nishizawa, H., Shoji, T., Miyajima, A., Miyoshi, M. & Abe, Y., 1998 1月 1, In: Analytical Sciences. 14, 6, p. 1133-1137 5 p.

  研究成果: Article › 査読

  Open Access

  • Plate Like Crystal 100%
  2 被引用数 (Scopus)

• Appearance of reverse transcriptase activity in human fetal thymus cells stimulated by human b-cell

  Ono, A., Saito, H., Tsuchiya, M., Nakamura, T., Higashinakagawa, T., Kondo, S. & Yoshimatsu, H., 1983 1月, In: the keio journal of medicine. 32, p. 73-80 8 p.

  研究成果: Article › 査読

  • RNA-Directed DNA Polymerase 100%
  • Human Activities 85%
  • Thymus Gland 82%
  • B-Lymphocytes 28%
  • Mitomycin 27%
  2 被引用数 (Scopus)

• Application of a dendritic algorithm for the evaluation of causal relationships of adverse events with health food

  Yamada, H., Ichimaru, K., Ono, A., Takahashisi, M., Matsumoto, K., Kosuge, K., Fujimoto, K., Waki, M., Nakashima, M. & Umegaki, K., 2012 11月, In: Japanese Journal of Clinical Pharmacology and Therapeutics. 43, 6, p. 399-402 4 p.

  研究成果: Article › 査読
  1 被引用数 (Scopus)

• Application of a new method, orthogonal projection to latent structure (OPLS) combined with principal component analysis (PCA), to screening of prostaglandin E₂ production inhibitory flavonoids in Scutellaria Root

  Huang, L., Fuchino, H., Kawahara, N., Narukawa, Y., Hada, N. & Kiuchi, F., 2016 10月 1, In: Journal of Natural Medicines. 70, 4, p. 731-739 9 p.

  研究成果: Article › 査読

  • Scutellaria 100%
  • Prostaglandin E2 81%
  • Principal Component Analysis 64%
  • Flavonoids 61%
  • Dinoprostone 58%
  11 被引用数 (Scopus)

• Application of enzyme- and microorganism-catalyzed reactions to organic synthesis

  Sugai, T., 1999 7月 1, In: Current Organic Chemistry. 3, 4, p. 373-406 34 p.

  研究成果: Article › 査読

  • Ester 100%
  • Enzymatic Hydrolysis 88%
  • Enzymatic Reaction 82%
  • Transesterification 80%
  • Nitrile 75%
  52 被引用数 (Scopus)

• Application of high pressure, induced by water freezing, to the direct asymmetric aldol reaction

  Hayashi, Y., Tsuboi, W., Shoji, M. & Suzuki, N., 2004 5月 24, In: Tetrahedron Letters. 45, 22, p. 4353-4356 4 p.

  研究成果: Article › 査読

  • 3-hydroxybutanal 100%
  • Aldol Reaction 62%
  • Freezing 55%
  • Enantioselectivity 47%
  • Temperature 39%
  56 被引用数 (Scopus)

• Application of high pressure induced by water-freezing to the direct catalytic asymmetric three-component List-Barbas-Mannich reaction

  Hayashi, Y., Tsuboi, W., Shoji, M. & Suzuki, N., 2003 9月 17, In: Journal of the American Chemical Society. 125, 37, p. 11208-11209 2 p.

  研究成果: Article › 査読

  • Enantioselectivity 100%
  • Freezing 53%
  • Temperature 35%
  • Water 33%
  • Pressure 32%
  136 被引用数 (Scopus)

• Application of Hydrazine-Embedded Heterocyclic Compounds to High Voltage Rechargeable Lithium Organic Batteries

  Shimizu, T., Yamamoto, K., Pandit, P., Yoshikawa, H. & Higashibayashi, S., 2018 12月 1, In: Scientific reports. 8, 1, 579.

  研究成果: Article › 査読

  • Heterocyclic Compounds 100%
  • hydrazine 90%
  • Lithium 66%
  • Electrodes 52%
  • carbazole 49%
  11 被引用数 (Scopus)

• Application of Indirect Comparison to the Drug Development Process: Forecasting Direct Comparison Study Results

  Kunitomi, T., Hashiguchi, M. & Mochizuki, M., 2016 9月, In: Journal of Clinical Pharmacology. 56, 9, p. 1165-1170 6 p.

  研究成果: Article › 査読

• Application of microbial enantiofacially selective hydrolysis in natural product synthesis

  Katoh, O., Sugai, T. & Ohta, H., 1994 10月, In: Tetrahedron: Asymmetry. 5, 10, p. 1935-1944 10 p.

  研究成果: Article › 査読

  • Enantiomers 100%
  • Lipases 88%
  • Ketones 81%
  • Baeyer-Villiger Oxidation 75%
  • Transesterification 72%
  26 被引用数 (Scopus)

• Application of radioimmunoassay for acetylcholine to physiological and pharmacological studies

  Kawashima, K., Fujimoto, K., Oohata, H. & Suzuki, T., 1989 1月 1, In: Journal of Pharmacobio-Dynamics. 12, 1, p. s-1

  研究成果: Article › 査読

• Application of the PKCYP-test in cases of altered CYP1A2 for multiple CYP systems in rat models of disease

  Matsunaga, N., Hattori, K., Iizasa, H., Kizu, J., Takanaka, A. & Nakashima, E., 2001, In: Biological and Pharmaceutical Bulletin. 24, 9, p. 1037-1043 7 p.

  研究成果: Article › 査読

  • Cytochrome P-450 CYP1A2 100%
  • Clearance 83%
  • Cytochrome P450 83%
  • Cytochrome P-450 Enzyme System 75%
  • Clint 54%
  3 被引用数 (Scopus)

• Application of the PKCYP-test to predict the amount of in vivo CYP2C11 using tolbutamide as a probe

  Matsunaga, N., Nishijima, T., Hattori, K., Iizasa, H., Yamamoto, K., Kizu, J., Takanaka, A., Morikawa, A. & Nakashima, E., 2001, In: Biological and Pharmaceutical Bulletin. 24, 11, p. 1305-1310 6 p.

  研究成果: Article › 査読

  • Tolbutamide 100%
  • Pharmacokinetics 50%
  • Probe 40%
  • Cytochrome P450 28%
  • Amount 28%
  11 被引用数 (Scopus)

• Application to the preparation of useful compounds based on enzyme- And microorganism-mediated reactions

  Fuhshuku, K. I., Nishiyama, S. & Sugai, T., 2006 6月, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 64, 6, p. 664-676 13 p.

  研究成果: Article › 査読

  Open Access

  • Chemical Transformation 100%
  • Purity 79%
  • Carbonyl Compound 75%
  • Occurrence in Nature 65%
  • Amide 56%
  4 被引用数 (Scopus)

• Approaching over 10 000-fold sensitivity increase in chiral capillary electrophoresis: Cation-selective exhaustive injection and sweeping cyclodextrin-modified micellar electrokinetic chromatography

  Mikuma, T., Iwata, Y. T., Miyaguchi, H., Kuwayama, K., Tsujikawa, K., Kanamori, T., Kanazawa, H. & Inoue, H., 2016 11月 1, In: ELECTROPHORESIS. 37, 22, p. 2970-2976 7 p.

  研究成果: Article › 査読

  • Micellar Electrokinetic Capillary Chromatography 100%
  • Chiral Capillary Electrophoresis 86%
  • Cyclodextrins 71%
  • Capillary Electrophoresis 68%
  • Cations 53%
  13 被引用数 (Scopus)