薬学部

2001

Elastin expression in cultured human keratinocytes: Exon 26A of elastin primary transcript is always included in terminally differentiated keratinocytes

Hirano, E., Okamoto, K., Matsubara, Y., Takehana, M., Kobayashi, S. & Tajima, S., 2001 10月 17, In: Archives of Dermatological Research. 293, 8, p. 430-433 4 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Epigallocatechin gallate (EGCG) inhibits the sulfation of 1-naphthol in a human colon carcinoma cell line, Caco-2

Isozaki, T. & Tamura, H. O., 2001, In: Biological and Pharmaceutical Bulletin. 24, 9, p. 1076-1078 3 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Expression of a small heat shock protein 27 (HSP27) in mouse skin tumors induced by UVB-irradiation

Kiriyama, M. T., Oka, M., Takehana, M. & Kobayashi, S., 2001, In: Biological and Pharmaceutical Bulletin. 24, 2, p. 197-200 4 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Expression profiling of sulfotransferases in human cell lines derived from extra-hepatic tissues

Tamura, H. O., Taniguchi, K., Havashi, E., Hiyoshi, Y. & Nagai, F., 2001, In: Biological and Pharmaceutical Bulletin. 24, 11, p. 1258-1262 5 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Fatty liver quantification with line scan echo planar spectroscopic imaging (LSEPSI)

Shinmoto, H., Oshio, K., Yuasa, Y., Tanimoto, A., Momoshima, S., Kuribayashi, S., Saito, H., Imai, Y. & Mulkern, R. V., 2001 11月, In: Nihon Igaku Hōshasen Gakkai zasshi. Nippon acta radiologica. 61, 13, p. 715-720 6 p.

研究成果: Article › 査読

FTY720, a novel immunosuppressive agent, induces apoptosis in Human Glioma Cells

Sonoda, Y., Yamamoto, D., Sakurai, S., Hasegawa, M., Aizu-Yokota, E., Momoi, T. & Kasahara, T., 2001 1月 17, In: Biochemical and Biophysical Research Communications. 281, 2, p. 282-288 7 p.

研究成果: Article › 査読

65 被引用数 (Scopus)

Functional expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors precedes the development of cholinergic phenotype in embryonic rat septal cells in culture

Suzuki, T., Matsugi, T., Takagi, R., Kanagawa, M., Hirata, M., Nakamura, T., Kudo, Y. & Kawashima, K., 2001 9月 28, In: Neuroscience Letters. 311, 2, p. 89-92 4 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Geranylgeranylacetone protects guinea pig gastric mucosal cells from gastric-stressor-induced necrosis by induction of heat-shock proteins

Tomisato, W., Tsutsumi, S., Tsuchiya, T. & Mizushima, T., 2001, In: Biological and Pharmaceutical Bulletin. 24, 8, p. 887-891 5 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

Inhibitory effect of fullerene derivatives on glutathione reductase

Mashino, T., Okuda, K., Hirota, T., Hirobe, M., Nagano, T. & Mochizuki, M., 2001, In: Fullerene Science and Technology. 9, 2, p. 191-196 6 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

Inhibitory effects of fullerene C₆₀ derivatives on endothelium-derived relaxation in rabbit thoracic aorta

Satoh, M., Mashino, T., Nagano, T., Hirobe, M., Takayanagi, I. & Koike, K., 2001, In: Fullerene Science and Technology. 9, 2, p. 141-151 11 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Interferon-associated retinopathy in a uniform regimen of natural interferon-α therapy for chronic hepatitis C

Saito, H., Ebinuma, H., Nagata, H., Inagaki, Y., Saito, Y., Wakabayashi, K., Takagi, T., Nakamura, M., Katsura, H., Oguchi, Y. & Ishii, H., 2001, In: Liver. 21, 3, p. 192-197 6 p.

研究成果: Article › 査読

44 被引用数 (Scopus)

Interferon regulatory factor 1 promoter polymorphism and response to type 1 interferon

Saito, H., Tada, S., Ebinuma, H., Wakabayashi, K., Takagi, T., Saito, Y., Nakamoto, N., Kurita, S. & Ishii, H., 2001 1月 1, In: Journal of Cellular Biochemistry. 81, SUPPL. 36, p. 191-200 10 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

Kinetic phenotypic diagnosis of N-acetylation polymorphism in patients based on ratio of urinary metabolites of salicylazosulfapyridine

Yokogawa, K., Nakaharu, T., Ishizaki, J., Ozaki, E., Takeda, Y., Mabuchi, H., Matsushita, R., Kimura, K., Nakashima, E., Ichimura, F. & Miyamoto, K. I., 2001 10月 28, In: International Journal of Pharmaceutics. 229, 1-2, p. 183-191 9 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Loading of mechanical pressure activates mitogen-activated protein kinase and early immediate gene in intestinal epithelial cells

Hirokawa, M., Miura, S., Kishikawa, H., Yoshida, H., Nakamizo, H., Higuchi, H., Nakatsumi, R. C., Suzuki, H., Saito, H. & Ishii, H., 2001, In: Digestive Diseases and Sciences. 46, 9, p. 1993-2003 11 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Microbial asymmetric reduction of α-hydroxyketones in the anti-Prelog selectivity

Tsujigami, T., Sugai, T. & Ohta, H., 2001 10月 15, In: Tetrahedron Asymmetry. 12, 18, p. 2543-2549 7 p.

研究成果: Article › 査読

48 被引用数 (Scopus)

Molecular mechanism for functional interaction between DnaA protein and acidic phospholipids. Identification of important amino acids

Makise, M., Mima, S., Tsuchiya, T. & Mizushima, T., 2001 3月 9, In: Journal of Biological Chemistry. 276, 10, p. 7450-7456 7 p.

研究成果: Article › 査読

29 被引用数 (Scopus)

NADH-dependent dehydroascorbate reductase in the rabbit lens

Akatsuka, I., Bando, M., Obazawa, H., Oka, M., Takehana, M. & Kobayashi, S., 2001 4月 1, In: Tokai Journal of Experimental and Clinical Medicine. 26, 1, p. 25-32 8 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

nhaG Na⁺/H⁺ antiporter gene of bacillus subtilis ATCC9372, which is missing in the complete genome sequence of strain 168, and properties of the antiporter

Gouda, T., Kuroda, M., Hiramatsu, T., Nozaki, K., Kuroda, T., Mizushima, T. & Tsuchiya, T., 2001 11月, In: Journal of biochemistry. 130, 5, p. 711-717 7 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Practical entry into the HIJKLM ring segment of ciguatoxin CTX3C

Oishi, T., Uehara, H., Nagumo, Y., Shoji, M., Le Brazidec, J. Y., Kosaka, M. & Hirama, M., 2001 2月 21, In: Chemical Communications. 4, p. 381-382 2 p.

研究成果: Article › 査読

57 被引用数 (Scopus)

Preparation of methyl ursodeoxycholate in an interface bioreactor: Use of a mixed solvent system to increase the solubilities of substrate and product

Oda, S., Sugai, T. & Ohta, H., 2001, In: Journal of Bioscience and Bioengineering. 92, 1, p. 86-88 3 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Preparation of methyl ursodeoxycholate via microbial reduction of methyl 7-ketolithocholate in an anaerobic interface bioreactor

Oda, S., Sugai, T. & Ohta, H., 2001 1月 1, In: Journal of Bioscience and Bioengineering. 91, 2, p. 202-207 6 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Presence of a genistein-responsive inhibitory mechanism on interleukin-1αa-induced NF-κkB activation

Tago, K., Funakoshi, M., Mano, H., Yanagisawa, K., Hayakawa, M., Kuroiwa, K., Iwahana, H., Kasahara, T. & Tominaga, S. I., 2001, In: European Journal of Biochemistry. 268, 24, p. 6526-6533 8 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Quantitative monitoring of the PRAME gene for the detection of minimal residual disease in leukaemia

Matsushita, M., Ikeda, H., Kizaki, M., Okamoto, S., Ogasawara, M., Ikeda, Y. & Kawakami, Y., 2001, In: British Journal of Haematology. 112, 4, p. 916-926 11 p.

研究成果: Article › 査読

74 被引用数 (Scopus)

Reduction of c-myc expression by an antisense approach under Cre/IoxP switching induces apoptosis in human liver cancer cells

Ebinuma, H., Saito, H., Kosuga, M., Wakabayashi, K., Saito, Y., Takagi, T., Nakamoto, N., Okuyama, T. & Ishii, H., 2001 6月 6, In: Journal of Cellular Physiology. 188, 1, p. 56-66 11 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor

Nakamura, M., Saito, H., Ebinuma, H., Wakabayashi, K., Saito, Y., Takagi, T., Nakamoto, N. & Ishii, H., 2001 5月 8, In: Journal of Cellular Physiology. 187, 3, p. 392-401 10 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Roles of MexXY- and MexAB-multidrug efflux pumps in intrinsic multidrug resistance of Pseudomonas aeruginosa PAO1

Morita, Y., Kimura, N., Mima, T., Mizushima, T. & Tsuchiya, T., 2001, In: Journal of General and Applied Microbiology. 47, 1, p. 27-32 6 p.

研究成果: Article › 査読

Open Access

71 被引用数 (Scopus)

Selective Loss of Sphingosine 1-Phosphate Signaling with No Obvious Phenotypic Abnormality in Mice Lacking Its G Protein-coupled Receptor, LP _B3/EDG-3

Ishii, I., Friedman, B., Ye, X., Kawamura, S., McGiffert, C., Contos, J. J. A., Kingsbury, M. A., Zhang, G., Brown, J. H. & Chun, J., 2001 9月 7, In: Journal of Biological Chemistry. 276, 36, p. 33697-33704 8 p.

研究成果: Article › 査読

237 被引用数 (Scopus)

Structure-effect relationship in the induction of mitotic phase-specific abnormality of centrosome integrity and multipolar spindles by steroidal estrogens and their derivatives in cultured mammalian cells

Ochi, T. & Oda, T., 2001 1月 1, In: Journal of Steroid Biochemistry and Molecular Biology. 78, 2, p. 113-122 10 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Studies on the constituents of Anaxagorea luzonensis A. GRAY II

Gonda, R., Takeda, T. & Akiyama, T., 2001 12月 1, In: Natural Medicines. 55, 6, 1 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Studies on the constituents of Leonotis nepetaefolia

Narukawa, Y., Shimizu, N. & Takeda, T., 2001 1月 1, In: Natural Medicines. 55, 2, p. 79-82 4 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Study on the problems in the adverse event report of clinical trials

Furukawa, H., Uchikata, M., Ishizaki, J., Matsushima, Y., Osada, S., Matsuda, S., Yokoyama, E., Shimizu, S., Bunko, H. & Miyamoto, K., 2001, In: Japanese Journal of Clinical Pharmacology and Therapeutics. 32, 6, p. 287-294 8 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Synergistic effect of indomethacin and adriamycin and cisplatin on tumor growth

Hattori, K., Matsushita, R., Kimura, K., Abe, Y. & Nakashima, E., 2001, In: Biological and Pharmaceutical Bulletin. 24, 10, p. 1214-1217 4 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones

Nicolaou, K. C., Namoto, K., Li, J., Ritzén, A., Ulven, T., Shoji, M., Zaharevitz, D., Gussio, R., Sackett, D. L., Ward, R. D., Hensler, A., Fojo, T. & Giannakakou, P., 2001 1月 1, In: ChemBioChem. 2, 1, p. 69-75 7 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

Synthesis of citronellyl acetate via a transacetylation to citronellol from acetyl coenzyme A produced from glucose and acetate in growing yeasts

Oda, S., Sugai, T. & Ohta, H., 2001, In: Chemistry Letters. 6, p. 500-501 2 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of enantiomers of indanoxazolidinone based on the lipase-catalyzed resolution of the corresponding N-carbamylamino derivative

Suzuki, M., Nagasawa, C. & Sugai, T., 2001 6月 4, In: Tetrahedron. 57, 23, p. 4841-4848 8 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Synthesis of methyl ursodeoxycholate via microbial reduction of methyl 7-ketolithocholate with Eubacterium aerofaciens JCM 7790 grown on two kinds of carbon and hydride sources, glucose and mannitol

Oda, S., Sugai, T. & Ohta, H., 2001 1月 1, In: Journal of Bioscience and Bioengineering. 91, 2, p. 178-183 6 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Th1 and Th2 cytokines differentially regulate the transformation of Kupffer cells into multinucleated giant cells but similarly enhance the Kupffer cell-induced hepatic stellate cell proliferation

Atsukawa, K., Saito, H., Tsukada, N., Akiba, Y., Toda, K., Kumagai, N., Kamegaya, Y. & Ishii, H., 2001 1月 1, In: Hepatology Research. 22, 2, p. 193-206 14 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Two new diterpenoids from Plectranthus nummularius BRIQ

Narukawa, Y., Shimizu, N., Shimotohno, K. & Takeda, T., 2001, In: Chemical and Pharmaceutical Bulletin. 49, 9, p. 1182-1184 3 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

2002

Access to enantiomerically pure intermediates for (−)-geosmin synthesis starting from (4aS,5S)-4,4a,5,6,7,8-hexahydro-5-hydroxy-4a-methyl-naphthalen-2(3H)-one

Fuhshuku, K. I. & Sugai, T., 2002 1月 1, In: Bioscience, Biotechnology and Biochemistry. 66, 10, p. 2267-2272 6 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Acidic phospholipids inhibit the DNA-binding activity of DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli

Makise, M., Mima, S., Katsu, T., Tsuchiya, T. & Mizushima, T., 2002, In: Molecular Microbiology. 46, 1, p. 245-256 12 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization.

Fujita, N., Sato, S., Katayama, K. & Tsuruo, T., 2002 8月 9, In: The Journal of biological chemistry. 277, 32, p. 28706-28713 8 p.

研究成果: Article › 査読

Open Access

296 被引用数 (Scopus)

Anandamide-induced neuroblastoma cell rounding via the CBI cannabinoid receptors

Ishii, I. & Chun, J., 2002 4月 16, In: NeuroReport. 13, 5, p. 593-596 4 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

An expeditious route to GlcNAc-Cbz-Asn by chemo-enzymatic synthesis

Tokuda, Y., Takahashi, Y., Matoishi, K., Ito, Y. & Sugai, T., 2002 1月 1, In: Synlett. 1, p. 57-60 4 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Antiapoptotic action of focal adhesion kinase (FAK) against ionizing radiation

Kasahara, T., Koguchi, E., Funakoshi, M., Aizu-yokota, E. & Sonoda, Y., 2002 1月 1, In: Antioxidants and Redox Signaling. 4, 3, p. 491-499 9 p.

研究成果: Article › 査読

74 被引用数 (Scopus)

Chemo-enzymatic synthesis of enantiomerically pure (R)-2-naphthylmethoxyacetic acid

Kimura, M., Kuboki, A. & Sugai, T., 2002 6月 10, In: Tetrahedron Asymmetry. 13, 10, p. 1059-1068 10 p.

研究成果: Article › 査読

36 被引用数 (Scopus)

Convergent synthesis of the HIJKLM ring fragment of ciguatoxin CTX3C

Uehara, H., Oishi, T., Inoue, M., Shoji, M., Nagumo, Y., Kosaka, M., Le Brazidec, J. Y. & Hirama, M., 2002 8月 5, In: Tetrahedron. 58, 32, p. 6493-6512 20 p.

研究成果: Article › 査読

56 被引用数 (Scopus)

Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines

Nagai, F., Hiyoshi, Y., Sugimachi, K. & Tamura, H. O., 2002 3月, In: Biological and Pharmaceutical Bulletin. 25, 3, p. 383-385 3 p.

研究成果: Article › 査読

74 被引用数 (Scopus)

Cytochrome P450-dependent neurosteroid synthesis in the rat brain hippocampal neurons

Kimoto, T., Tsurugizawa, T., Ohta, Y., Makino, J., Tamura, H., Hojo, Y., Enami, T. & Kawato, S., 2002 11月 1, In: International Congress Series. 1233, C, p. 127-137 11 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Cytotoxicity of estradiol, equilin, equilenin, and their derivatives on Chinese hamster V79 cells

Oda, T., Ikeda, N., Nakashima, S. & Sato, Y., 2002 2月 18, In: Drug and Chemical Toxicology. 25, 1, p. 75-82 8 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Determination of omeprazole and its metabolites in human plasma by liquid chromatography-mass spectrometry

Kanazawa, H., Okada, A., Matsushima, Y., Yokota, H., Okubo, S., Mashige, F. & Nakahara, K., 2002 3月 8, In: Journal of Chromatography A. 949, 1-2, p. 1-9 9 p.

研究成果: Article › 査読

50 被引用数 (Scopus)

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