薬学部

研究成果

年別の研究成果 1975 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 2191 Article
• 154 Review article
• 23 Comment/debate
• 22 Letter
• 55 その他
  • 19 Editorial
  • 18 Chapter
  • 7 Paper
  • 6 Conference contribution
  • 5 Short survey

年別の研究成果

年別の研究成果

検索結果

• 2006

  Ets-1-dependent expression of vascular endothelial growth factor receptors is activated by latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus through interaction with Daxx

  Murakami, Y., Yamagoe, S., Noguchi, K., Takebe, Y., Takahashi, N., Uehara, Y. & Fukazawa, H., 2006 9月 22, In: Journal of Biological Chemistry. 281, 38, p. 28113-28121 9 p.

  研究成果: Article › 査読

  • latency-associated nuclear antigen 100%
  • Human Herpesvirus 8 75%
  • Vascular Endothelial Growth Factor Receptor 70%
  • Antigen 49%
  • Vascular Endothelial Growth Factor Receptor-1 21%
  47 被引用数 (Scopus)

• Expression profiling of drug metabolizing enzymes in rat syncytiotrophoblast cell lines

  Ikeda, Y., Nakashima, E. & Tamura, H., 2006, In: Journal of Health Science. 52, 5, p. 633-636 4 p.

  研究成果: Article › 査読

  • Xenobiotic Agent 100%
  • Trophoblasts 94%
  • Cytochrome P450 92%
  • Glutathione 77%
  • Protective 71%
  2 被引用数 (Scopus)

• Functional gene cloning and characterization of MdeA, a multidrug efflux pump from Staphylococcus aureus

  Yamada, Y., Shiota, S., Mizushima, T., Kuroda, T. & Tsuchiya, T., 2006 4月, In: Biological and Pharmaceutical Bulletin. 29, 4, p. 801-804 4 p.

  研究成果: Article › 査読

  • Tetraphenylphosphonium 100%
  • Pump 69%
  • Organism Cloning 65%
  • Staphylococcus aureus 61%
  • bisbenzimide ethoxide trihydrochloride 58%
  23 被引用数 (Scopus)

• Glycyrrhizin derivative inhibits eotaxin 1 production via STAT6 in human lung fibroblasts

  Matsui, S., Sonoda, Y., Sekiya, T., Aizu-Yokota, E. & Kasahara, T., 2006 3月, In: International Immunopharmacology. 6, 3, p. 369-375 7 p.

  研究成果: Article › 査読

  • Chemokine CCL11 100%
  • STAT6 Transcription Factor 95%
  • Glycyrrhizic Acid 87%
  • Fibroblasts 45%
  • hydroxide ion 38%
  28 被引用数 (Scopus)

• Highly diastereo- and enantioselective direct aldol reactions in water

  Hayashi, Y., Sumiya, T., Takahashi, J., Gotoh, H., Urushima, T. & Shoji, M., 2006 1月 30, In: Angewandte Chemie - International Edition. 45, 6, p. 958-961 4 p.

  研究成果: Article › 査読

  • Aldol Reaction 100%
  • Hydroxyproline 88%
  • Enantioselectivity 88%
  • Catalysts 74%
  • Green 60%
  469 被引用数 (Scopus)

• Identification of the time-point which gives a plasma rabeprazole concentration that adequately reflects the area under the concentration-time curve

  Niioka, T., Uno, T., Yasui-Furukori, N., Shimizu, M., Sugawara, K. & Tateishi, T., 2006 10月, In: European Journal of Clinical Pharmacology. 62, 10, p. 855-861 7 p.

  研究成果: Article › 査読

  • Rabeprazole 100%
  • Cytochrome P-450 CYP2C19 72%
  • Area Under Curve 53%
  • Genotype 39%
  • Cross-Over Studies 20%
  7 被引用数 (Scopus)

• Increased F2-isoprostane levels in the rat brain and plasma caused by oxidative stress and aging, and inhibitory effect of vitamin E

  Nishio, T., Miyadera, R., Sakai, R., Abe, K., Kanazawa, H., Fukui, K. & Urano, S., 2006 5月, In: Journal of Clinical Biochemistry and Nutrition. 38, 3, p. 161-166 6 p.

  研究成果: Article › 査読

  • Vitamin E 79%
  • Oxidative Stress 65%
  • Plasma 40%
  • Hyperoxia 35%
  • Brain 32%
  13 被引用数 (Scopus)

• Increased serum and hepatic tissue levels of interleukin-18 in patients with fulminant hepatic failure

  Shinoda, M., Wakabayashi, G., Shimazu, M., Saito, H., Hoshino, K., Tanabe, M., Morikawa, Y., Endo, S., Ishii, H. & Kitajima, M., 2006 11月, In: Journal of Gastroenterology and Hepatology (Australia). 21, 11, p. 1731-1736 6 p.

  研究成果: Article › 査読

  • Interleukin-18 100%
  • Acute Liver Failure 99%
  • Liver 43%
  • Serum 38%
  • Cytokines 17%
  16 被引用数 (Scopus)

• Lack of dose-dependent effects of itraconazole on the pharmacokinetic interaction with fexofenadine

  Uno, T., Shimizu, M., Sugawara, K. & Tateishi, T., 2006, In: Drug Metabolism and Disposition. 34, 11, p. 1875-1879 5 p.

  研究成果: Article › 査読

  • Fexofenadine 100%
  • fexofenadine 92%
  • Itraconazole 87%
  • Pharmacokinetics 44%
  • Dose 31%
  29 被引用数 (Scopus)

• Large nonlinear effect observed in the enantiomeric excess of proline in solution and that in the solid state

  Hayashi, Y., Matsuzawa, M., Yamaguchi, J., Yonehara, S., Matsumoto, Y., Shoji, M., Hashizume, D. & Koshino, H., 2006 7月 10, In: Angewandte Chemie - International Edition. 45, 28, p. 4593-4597 5 p.

  研究成果: Article › 査読

  • Chirality 100%
  • Proline 65%
  • Enantiomer 50%
  • Crystallization 34%
  • Dissolution 33%
  105 被引用数 (Scopus)

• Metabolic conversion of 24-methyl-Δ²⁵-cholesterol to 24-methylcholesterol in higher plants

  Takahashi, K., Nasu, K., Mashino, T., Morisaki, M., Hara, N. & Fujimoto, Y., 2006 2月 1, In: Bioorganic and Medicinal Chemistry. 14, 3, p. 732-738 7 p.

  研究成果: Article › 査読

  • 24-methyldesmosterol 100%
  • campesterol 64%
  • Campesterol 60%
  • Metabolic 32%
  • Cholesterol 29%
  2 被引用数 (Scopus)

• Pharmacokinetics of fentanyl after single intravenous injection and constant rate infusion in dogs

  Sano, T., Nishimura, R., Kanazawa, H., Igarashi, E., Nagata, Y., Mochizuki, M. & Sasaki, N., 2006 7月, In: Veterinary Anaesthesia and Analgesia. 33, 4, p. 266-273 8 p.

  研究成果: Article › 査読

  • fentanyl 100%
  • Fentanyl 76%
  • intravenous injection 73%
  • pharmacokinetics 69%
  • Intravenous Injections 67%
  79 被引用数 (Scopus)

• Possible involvement of allogeneic antigens recognised by donor-derived CD4 ⁺ cytotoxic T cells in selective GVL effects after stem cell transplantation of patients with haematological malignancy

  Matsushita, M., Yamazaki, R., Ikeda, H., Mori, T., Sumimoto, H., Fujita, T., Okamoto, S., Ikeda, Y. & Kawakami, Y., 2006 1月 1, In: British Journal of Haematology. 132, 1, p. 56-65 10 p.

  研究成果: Article › 査読

  • Stem Cell Transplantation 100%
  • HLA Antigens 98%
  • Hematologic Neoplasms 96%
  • Cytotoxic T-Lymphocytes 88%
  • Tissue Donors 74%
  11 被引用数 (Scopus)

• Recurrence of autoimmune disease after autologous peripheral blood stem cell transplantation for multiple myeloma

  Isshiki, I., Okamoto, S., Kakimoto, T., Chen, C. K., Mori, T., Yokoyama, K., Hattori, Y. & Ikeda, Y., 2006 11月, In: International journal of hematology. 84, 4, p. 354-358 5 p.

  研究成果: Article › 査読

  • Peripheral Blood Stem Cell Transplantation 100%
  • Multiple Myeloma 74%
  • Autoimmune Diseases 65%
  • Stem Cell Transplantation 59%
  • Recurrence 43%
  5 被引用数 (Scopus)

• Screening, substrate specificity and stereoselectivity of yeast strains, which reduce sterically hindered isopropyl ketones

  Hiraoka, C., Matsuda, M., Suzuki, Y., Fujieda, S., Tomita, M., Fuhshuku, K. I., Obata, R., Nishiyama, S. & Sugai, T., 2006 12月 27, In: Tetrahedron Asymmetry. 17, 24, p. 3358-3367 10 p.

  研究成果: Article › 査読

  • Stereoselectivity 100%
  • Ketones 68%
  • ketones 62%
  • yeast 57%
  • Yeast 57%
  19 被引用数 (Scopus)

• Sensitive determination of itraconazole and its active metabolite in human plasma by column-switching high-performance liquid chromatography with ultraviolet detection

  Uno, T., Shimizu, M., Sugawara, K. & Tateishi, T., 2006 8月 1, In: Therapeutic Drug Monitoring. 28, 4, p. 526-531 6 p.

  研究成果: Article › 査読

  • hydroxyitraconazole 100%
  • Itraconazole 62%
  • High Pressure Liquid Chromatography 42%
  • acetonitrile 18%
  • Buffers 13%
  20 被引用数 (Scopus)

• Sensitive determination of omeprazole and its two main metabolites in human plasma by column-switching high-performance liquid chromatography: Application to pharmacokinetic study in relation to CYP2C19 genotypes

  Shimizu, M., Uno, T., Niioka, T., Yaui-Furukori, N., Takahata, T., Sugawara, K. & Tateishi, T., 2006 3月 7, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 832, 2, p. 241-248 8 p.

  研究成果: Article › 査読

  • Omeprazole 100%
  • Cytochrome P-450 CYP2C19 92%
  • omeprazole sulfone 90%
  • 5-hydroxymethylomeprazole 87%
  • High Pressure Liquid Chromatography 58%
  47 被引用数 (Scopus)

• Serodiagnostic potential of chemically synthesized glycosphingolipid antigens in an enzyme-linked immunosorbent assay for alveolar echinococcosis

  Yamano, K., Hada, N., Yamamura, T., Takeda, T., Honma, H. & Sawada, Y., 2006 12月, In: Journal of Helminthology. 80, 4, p. 387-391 5 p.

  研究成果: Article › 査読

  • Alveolar echinococcosis 100%
  • glycosphingolipids 89%
  • echinococcosis 88%
  • Glycosphingolipids 87%
  • enzyme-linked immunosorbent assay 53%
  16 被引用数 (Scopus)

• Structural characterization of room-temperature synthesized fullerene nanowhiskers

  Miyazawa, K., Minato, J. I., Mashino, T., Nakamura, S., Fujino, M. & Suga, T., 2006 6月 14, In: Nukleonika. 51, SUPPL. 1, p. S41-S48

  研究成果: Article › 査読

  • Nanowhiskers 100%
  • Fullerenes 80%
  • fullerene 72%
  • xylene 67%
  • fullerenes 53%
  12 被引用数 (Scopus)

• Study of temperature-responsibility on the surfaces of a thermo-responsive polymer modified stationary phase

  Ayano, E., Okada, Y., Sakamoto, C., Kanazawa, H., Kikuchi, A. & Okano, T., 2006 6月 30, In: Journal of Chromatography A. 1119, 1-2, p. 51-57 7 p.

  研究成果: Article › 査読

  • poly-N-isopropylacrylamide 100%
  • Polymers 70%
  • Temperature 56%
  • Surface 25%
  • Steroid 20%
  47 被引用数 (Scopus)

• Superoxide anion and reactive oxygen species and redox regulation in the liver

  Saito, H., Yokoyama, H. & Hibi, T., 2006 1月, In: Nippon Shokakibyo Gakkai zasshi The Japanese journal of gastro-enterology. 103, 1, p. 15-22 8 p.

  研究成果: Article › 査読
  1 被引用数 (Scopus)

• Syntheses of new model compounds related to an antigenic epitope from Bupleurum falcatum L. and their distributions in various ganglioside- phospholipid monolayers

  Hada, N., Jin, Y., Takeda, T., Ohtsuka, I. & Yokoyama, S., 2006, In: Chemical and Pharmaceutical Bulletin. 54, 9, p. 1281-1284 4 p.

  研究成果: Article › 査読

  • Bupleurum 100%
  • Gangliosides 73%
  • Atomic Force Microscopy 72%
  • Epitope 61%
  • Phospholipids 53%
  5 被引用数 (Scopus)

• Synthesis and biological assessment of hemiacetal spiro derivatives towards development of efficient chemotherapeutic agent

  Ogamino, T., Ohnishi, S., Ishikawa, Y., Sugai, T., Obata, R. & Nishiyama, S., 2006 3月, In: Science and Technology of Advanced Materials. 7, 2, p. 175-183 9 p.

  研究成果: Article › 査読

  • Spiro Compound 100%
  • Hemiacetal 89%
  • Bioassay 67%
  • Antineoplastic Agent 62%
  • Amino Groups 59%
  12 被引用数 (Scopus)

• Synthesis of a novel glycosphingolipid from the millipede, Parafontaria laminata armigera, and the assembly of its carbohydrate moiety into multivalent structures

  Hada, N., Sonoda, Y. & Takeda, T., 2006 7月 24, In: Carbohydrate Research. 341, 10, p. 1341-1352 12 p.

  研究成果: Article › 査読

  • Glycosphingolipid 100%
  • Glycosphingolipids 99%
  • Glycoconjugates 97%
  • Glycolipids 90%
  • Amides 90%
  20 被引用数 (Scopus)

• TNF-receptor associated factor 6-deficient fibroblast is sensitive to the TNF-α-induced cell death: Involvement of reactive oxygen species

  Ichikawa, D., Funakoshi-Tago, M., Aizu-Yokota, E., Sonoda, Y., Inoue, J. I. & Kasahara, T., 2006 12月 8, In: Biochemical and Biophysical Research Communications. 351, 1, p. 93-98 6 p.

  研究成果: Article › 査読

  • TNF Receptor-Associated Factor 6 100%
  • Cell Death 73%
  • Reactive Oxygen Metabolite 64%
  • Reactive Oxygen Species 55%
  • Fibroblasts 51%
  8 被引用数 (Scopus)

• Turmeric and curcumin modulate the conjugation of 1-naphthol in caco-2 cells

  Naganuma, M., Saruwatari, A., Okamura, S. & Tamura, H., 2006, In: Biological and Pharmaceutical Bulletin. 29, 7, p. 1476-1479 4 p.

  研究成果: Article › 査読

  • 1-naphthol 100%
  • 1-Naphthol 80%
  • Curcuma 78%
  • Caco-2 Cells 71%
  • Curcumin 69%
  39 被引用数 (Scopus)
• 2007

  A case of fulminant hepatitis E treated with artificial liver support

  Fujiyama, Y., Yamagishi, Y., Kikuchi, M., Shimoji, K., Kato, S., Nagata, H., Saito, H., Hibi, T. & Mishiro, S., 2007 2月 1, In: Japanese Journal of Gastroenterology. 104, 2, p. 219-225 7 p.

  研究成果: Article › 査読

  • Artificial Liver 100%
  • Hepatitis E 96%
  • Massive Hepatic Necrosis 92%
  • Hepatitis E virus 91%
  • China 55%
  1 被引用数 (Scopus)

• A developed determination of midazolam and 1′-hydroxymidazolam in plasma by liquid chromatography-mass spectrometry: Application of human pharmacokinetic study for measurement of CYP3A activity

  Shimizu, M., Uno, T., Tamura, H. O., Kanazawa, H., Murakami, I., Sugawara, K. & Tateishi, T., 2007 3月 1, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 847, 2, p. 275-281 7 p.

  研究成果: Article › 査読

  • 1-hydroxymethylmidazolam 100%
  • Midazolam 81%
  • Cytochrome P-450 CYP3A 62%
  • Liquid Chromatography 57%
  • Liquid Chromatography Mass Spectrometry (LCMS) 56%
  29 被引用数 (Scopus)

• Ames test-negative carcinogen, ortho-phenyl phenol, binds tubulin and causes aneuploidy in budding yeast

  Nunoshiba, T., Watanabe, E., Takahashi, T., Daigaku, Y., Ishikawa, S., Mochizuki, M., Ui, A., Enomoto, T. & Yamamoto, K., 2007 4月 1, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 617, 1-2, p. 90-97 8 p.

  研究成果: Article › 査読

  • Carcinogenicity Tests 100%
  • Saccharomycetales 75%
  • Phenol 72%
  • Aneuploidy 66%
  • Tubulin 66%
  12 被引用数 (Scopus)

• Analysis of melatonin using a pH- and temperature-responsive aqueous chromatography system

  Ayano, E., Suzuki, Y., Kanezawa, M., Sakamoto, C., Morita-Murase, Y., Nagata, Y., Kanazawa, H., Kikuchi, A. & Okano, T., 2007 7月 13, In: Journal of Chromatography A. 1156, 1-2 SPEC. ISS., p. 213-219 7 p.

  研究成果: Article › 査読

  • Melatonin 100%
  • Chromatography 75%
  • Temperature 54%
  • Copolymer 50%
  • Intracerebral 41%
  25 被引用数 (Scopus)

• Breast cancer resistance protein (BCRP) affected acquired resistance to gefitinib in a "never-smoked" female patient with advanced non-small cell lung cancer

  Usuda, J., Ohira, T., Suga, Y., Oikawa, T., Ichinose, S., Inoue, T., Ohtani, K., Maehara, S., Imai, K., Kubota, M., Tsunoda, Y., Tsutsui, H., Furukawa, K., Okunaka, T., Sugimoto, Y. & Kato, H., 2007 11月, In: Lung Cancer. 58, 2, p. 296-299 4 p.

  研究成果: Article › 査読

  • Gefitinib 100%
  • Non-Small Cell Lung Carcinoma 71%
  • Codon 52%
  • Breast Neoplasms 50%
  • ErbB Receptors 50%
  28 被引用数 (Scopus)

• Changes in the expression of cytochrome P450 genes in hemin-induced differentiated K562 cells

  Nagai, F., Shimizu, M., Sakamoto, T., Kobayashi, T. & Tamura, H., 2007 10月, In: Biological and Pharmaceutical Bulletin. 30, 10, p. 1954-1957 4 p.

  研究成果: Article › 査読

  • Hemin 100%
  • K562 Cells 88%
  • Cytochrome P-450 CYP3A 84%
  • Cytochrome P450 79%
  • Cytochrome P-450 Enzyme System 72%
  2 被引用数 (Scopus)

• Changes in the gene expression patterns of the cytochrome P450s in selenite-induced cataracts in the rat

  Nakamura, K., Fujiki, T. & Tamura, H. O., 2007 6月, In: Journal of Health Science. 53, 3, p. 347-350 4 p.

  研究成果: Article › 査読

  • Selenious Acid 100%
  • Selenites 86%
  • Cytochromes 77%
  • Cataract 63%
  • Cytochrome 59%
  2 被引用数 (Scopus)

• Chemical constituents of Nepalese propolis (II)

  Shrestha, S. P., Narukawa, Y. & Takeda, T., 2007 6月, In: Chemical and Pharmaceutical Bulletin. 55, 6, p. 926-929 4 p.

  研究成果: Article › 査読

  • flavan-3-ol 100%
  • Propolis 76%
  • Isoflavones 73%
  • Nepal 68%
  • Flavonoids 55%
  30 被引用数 (Scopus)

• Cloning and expression of a novel sulfotransferase with unique substrate specificity from Bombyx mori

  Hattori, K., Hirayama, M., Suzuki, H., Hamamoto, H., Sekimizu, K. & Tamura, H. O., 2007, In: Bioscience, Biotechnology and Biochemistry. 71, 4, p. 1044-1051 8 p.

  研究成果: Article › 査読

  • Sulfotransferases 100%
  • Bombyx 98%
  • Substrate Specificity 79%
  • Complementary DNA 74%
  • Organism Cloning 65%
  13 被引用数 (Scopus)

• Complexity of the HVR-1 quasispecies and disease activity in patients with hepatitis C

  Kumagai, N., Kaneko, F., Tsunematsu, S., Tsuchimoto, K., Tada, S., Saito, H. & Hibi, T., 2007 7月 1, In: European Journal of Clinical Investigation. 37, 7, p. 566-572 7 p.

  研究成果: Article › 査読

  • Quasispecies 100%
  • Hepatitis C 72%
  • Alanine 68%
  • Hepacivirus 65%
  • Chronic Hepatitis C 61%
  4 被引用数 (Scopus)

• Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expression

  Nakazawa, Y., Suzuki, M., Manabe, N., Yamada, T., Kihara-Negishi, F., Sakurai, T., Tenen, D. G., Iwama, A., Mochizuki, M. & Oikawa, T., 2007 5月 24, In: Oncogene. 26, 24, p. 3541-3550 10 p.

  研究成果: Article › 査読

  • Intercellular Signaling Peptides and Proteins 100%
  • Transcription Factors 92%
  • Gene Expression 73%
  • Transcriptional Activation 22%
  • Binding Sites 18%
  30 被引用数 (Scopus)

• Cross-linkable Nitrosamines with a Chloroalkyl Group as Candidates for Anticancer Lead Compounds

  Ishikawa, S. & Mochizuki, M., 2007, In: Genes and Environment. 29, 1, p. 1-10 10 p.

  研究成果: Article › 査読

  • lead compound 100%
  • nitrosamine 95%
  • Nitrosamines 94%
  • Lead 63%
  • DNA 57%
  4 被引用数 (Scopus)

• Cytotoxicity of lissoclibadins and lissoclinotoxins, isolated from a tropical ascidian Lissoclinum cf. badium, against human solid-tumor-derived cell lines

  Oda, T., Kamoshita, K., Maruyama, S., Masuda, K., Nishimoto, M., Xu, J., Ukai, K., Mangindaan, R. E. P. & Namikoshi, M., 2007 2月, In: Biological and Pharmaceutical Bulletin. 30, 2, p. 385-387 3 p.

  研究成果: Article › 査読

  • Urochordata 100%
  • Sulfides 94%
  • Lissoclibadin 3 85%
  • Lissoclibadin 2 85%
  • Tumor Cell Line 72%
  25 被引用数 (Scopus)

• Differential effects of the ascorbyl and tocopheryl derivative on the methamphetamine-induced toxic behavior and toxicity

  Ito, S., Mori, T., Kanazawa, H. & Sawaguchi, T., 2007 10月 30, In: Toxicology. 240, 1-2, p. 96-110 15 p.

  研究成果: Article › 査読

  • Methamphetamine 100%
  • Toxic 56%
  • Poisons 56%
  • Morphine 52%
  • Self-Injurious Behavior 26%
  16 被引用数 (Scopus)

• Diminished antigen-specific IgG₁ and interleukin-6 production and acetylcholinesterase expression in combined M₁ and M₅ muscarinic acetylcholine receptor knockout mice

  Fujii, Y. X., Tashiro, A., Arimoto, K., Fujigaya, H., Moriwaki, Y., Misawa, H., Fujii, T., Matsui, M., Kasahara, T. & Kawashima, K., 2007 8月, In: Journal of Neuroimmunology. 188, 1-2, p. 80-85 6 p.

  研究成果: Article › 査読

  • Acetylcholinesterase 100%
  • Muscarinic Receptors 98%
  • Knockout Mice 82%
  • Ovalbumin 75%
  • Interleukin-6 69%
  42 被引用数 (Scopus)

• DMPO-OH radical formation from 5,5-dimethyl-1-pyrroline N-oxide (DMPO) in hot water

  Shoji, T., Li, L., Abe, Y., Ogata, M., Ishimoto, Y., Gonda, R., Mashino, T., Mochizuki, M., Uemoto, M. & Miyata, N., 2007 2月, In: analytical sciences. 23, 2, p. 219-221 3 p.

  研究成果: Article › 査読

  • Mannitol 56%
  • Radical Scavenger 52%
  • Aqueous Solution 24%
  • Dioxygen 22%
  21 被引用数 (Scopus)

• Dry and wet prolines for asymmetric organic solvent-free aldehyde-aldehyde and aldehyde-ketone aldol reactions

  Hayashi, Y., Aratake, S., Itoh, T., Okano, T., Sumiya, T. & Shoji, M., 2007, In: Chemical Communications. 9, p. 957-959 3 p.

  研究成果: Article › 査読

  • Aldehydes 100%
  • Solvent Free Reaction 99%
  • Ketones 98%
  • Organic solvents 97%
  • Aldol Reaction 78%
  121 被引用数 (Scopus)

• Enhanced serum antigen-specific IgG₁ and proinflammatory cytokine production in nicotinic acetylcholine receptor α7 subunit gene knockout mice

  Fujii, Y. X., Fujigaya, H., Moriwaki, Y., Misawa, H., Kasahara, T., Grando, S. A. & Kawashima, K., 2007 9月, In: Journal of Neuroimmunology. 189, 1-2, p. 69-74 6 p.

  研究成果: Article › 査読

  • Gene Knockout Techniques 100%
  • Nicotinic Receptors 90%
  • Knockout Mice 75%
  • Immunoglobulin G 62%
  • Antigens 52%
  75 被引用数 (Scopus)

• Expression and function of genes encoding cholinergic components in murine immune cells

  Kawashima, K., Yoshikawa, K., Fujii, Y. X., Moriwaki, Y. & Misawa, H., 2007 5月 30, In: Life Sciences. 80, 24-25, p. 2314-2319 6 p.

  研究成果: Article › 査読

  • Cholinergic 100%
  • Mononuclear Leukocytes 80%
  • Cholinergic Agents 73%
  • Dendritic Cells 70%
  • Acetylcholine 62%
  170 被引用数 (Scopus)

• First total synthesis of modiolide A, based on the whole-cell yeast-catalyzed asymmetric reduction of a propargyl ketone

  Matsuda, M., Yamazaki, T., Fuhshuku, K. I. & Sugai, T., 2007 9月 3, In: Tetrahedron. 63, 36, p. 8752-8760 9 p.

  研究成果: Article › 査読

  • modiolide A 100%
  • Lactones 50%
  • Ketones 49%
  • Total Synthesis 33%
  • Yeasts 31%
  28 被引用数 (Scopus)

• Flavonoids inhibit breast cancer resistance protein-mediated drug resistance: Transporter specificity and structure-activity relationship

  Katayama, K., Masuyama, K., Yoshioka, S., Hasegawa, H., Mitsuhashi, J. & Sugimoto, Y., 2007 11月, In: Cancer Chemotherapy and Pharmacology. 60, 6, p. 789-797 9 p.

  研究成果: Article › 査読

  • Structure-Activity Relationship 100%
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 93%
  • Flavonoids 86%
  • Flavonoid 81%
  • Drug Resistance 78%
  96 被引用数 (Scopus)

• Focal adhesion kinase determines the fate of death or survival of cells in response to TNFα in the presence of actinomycin D

  Takahashi, R., Sonoda, Y., Ichikawa, D., Yoshida, N., Eriko, A. Y. & Tadashi, K., 2007 4月, In: Biochimica et Biophysica Acta - General Subjects. 1770, 4, p. 518-526 9 p.

  研究成果: Article › 査読

  • Actinomycin D 100%
  • Focal Adhesion Protein-Tyrosine Kinases 91%
  • Dactinomycin 83%
  • Cell Survival 55%
  • Death Domain Receptor Signaling Adaptor Proteins 35%
  24 被引用数 (Scopus)

• Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis

  Tanaka, K. I., Namba, T., Arai, Y., Fujimoto, M., Adachi, H., Sobue, G., Takeuchi, K., Nakai, A. & Mizushima, T., 2007 8月 10, In: Journal of Biological Chemistry. 282, 32, p. 23240-23252 13 p.

  研究成果: Article › 査読

  • HSP70 Heat-Shock Proteins 100%
  • Heat-Shock Response 90%
  • Colitis 84%
  • Mouse Hsf1 protein 80%
  • Protective 67%
  120 被引用数 (Scopus)

• Hepatocyte growth factor and c-Met expression in pericytes: Implications for atherosclerotic plaque development

  Liu, Y., Wilkinson, F. L., Kirton, J. P., Jeziorska, M., Iizasa, H., Sai, Y., Nakashima, E., Heagerty, A. M., Canfield, A. E., Alexander, M. Y. & Alexander, M. Y., 2007 5月 1, In: Journal of Pathology. 212, 1, p. 12-19 8 p.

  研究成果: Article › 査読

  • Pericytes 100%
  • Hepatocyte Growth Factor 97%
  • Atherosclerotic Plaques 85%
  • Microvessels 20%
  • human HGF protein 16%
  50 被引用数 (Scopus)