薬学部

研究成果

年別の研究成果 1975 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 2213 Article
• 156 Review article
• 24 Comment/debate
• 23 Letter
• 55 その他
  • 19 Editorial
  • 18 Chapter
  • 7 Paper
  • 6 Conference contribution
  • 5 Short survey

年別の研究成果

年別の研究成果

検索結果

• 1995

  ANTIHYPERTENSIVE EFFECTS, DETERMINED BY A TELEMETRY METHOD, OF TRICHLOROMETHIAZIDE AND 7–O‐ETHYLFANGCHINOLINE, A DERIVATIVE OF TETRANDRINE, IN SPONTANEOUSLY HYPERTENSIVE RATS

  Kawashima, K., Negishi, T., Amano, H., Fujimoto, K., Suzuki, T. & Fujii, T., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S300-S301

  研究成果: Article › 査読

  • Trichlormethiazide 100%
  • tetrandrine 88%
  • Telemetry 72%
  • Inbred SHR Rats 61%
  • Antihypertensive Agents 51%
  3 被引用数 (Scopus)

• A recessive mutant of the U937 cell line acquired resistance to anti-Fas and anti-p55 tumor necrosis factor receptor antibody-induced apoptosis

  Noguchi, K., Naito, M., Kataoka, S., Yonehara, S. & Tsuruo, T., 1995 1月 1, In: Cell Growth and Differentiation. 6, 10, p. 1271-1277 7 p.

  研究成果: Article › 査読

  • U937 Cells 100%
  • Tumor Necrosis Factor Receptors 90%
  • recombinant human tumor necrosis factor-binding protein-1 57%
  • Apoptosis 48%
  • Cell Line 46%
  21 被引用数 (Scopus)

• Biocatalysts-Mediated Preparation of Optically Active Hydroxy Acids

  Sugai, T., Tsuchiya, S., Ohta, H. & Mochizuki, N., 1995, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 53, 1, p. 32-42 11 p.

  研究成果: Article › 査読

  Open Access

  • Mandelic Acid 100%
  • Cyanohydrin 98%
  • Ester 91%
  • Sialic Acid 82%
  • Acid 78%
  2 被引用数 (Scopus)

• Biochemical Asymmetric Synthesis and Its Application to Chemical Synthesis of Bioactive Compounds

  Sugai, T., 1995, In: nippon nogeikagaku kaishi. 69, 1, p. 9-16 8 p.

  研究成果: Article › 査読
  1 被引用数 (Scopus)

• Changes in high mannose-type glycoproteins of peripheral blood mononuclear cells in cirrhosis patients

  Miyaguchi, S., Morizane, T., Kagawa, T., Guevara, F. M., Saito, H. & Tsuchiya, M., 1995 1月, In: International Hepatology Communications. 3, 1, p. 41-47 7 p.

  研究成果: Article › 査読

  • Mannose 100%
  • Glycoproteins 73%
  • Blood Cells 70%
  • Liver Cirrhosis 66%
  • Fibrosis 63%

• Chemo-enzymatic synthesis of (R,R)-(-)-Pyrenophorin

  Sugai, T., Katoh, O. & Ohta, H., 1995 10月 30, In: Tetrahedron. 51, 44, p. 11987-11998 12 p.

  研究成果: Article › 査読

  • Lactones 100%
  • Lipase 85%
  • Lactone 73%
  • sulcatol 66%
  • methylheptenone 56%
  54 被引用数 (Scopus)

• Control by phosphatidylglycerol of expression of the flhD gene in Escherichia coli

  Mizushima, T., Koyanagi, R., Suzuki, E., Tomura, A., Kutsukake, K., Miki, T. & Sekimizu, K., 1995 12月 14, In: BBA - General Subjects. 1245, 3, p. 397-401 5 p.

  研究成果: Article › 査読

  • Phosphatidylglycerols 100%
  • Phosphatidylglycerol 99%
  • Escherichia coli 53%
  • Gene Expression 45%
  • Genes 30%
  17 被引用数 (Scopus)

• Determination of medetomidine, atipamezole and midazolam in pig plasma by liquid chromatography‐mass spectrometry

  Kanazawa, H., Nishimura, R., Sasaki, N., Takeuchi, A., Takai, N., Nagata, Y. & Matsushima, Y., 1995 1月 1, In: Biomedical Chromatography. 9, 4, p. 188-191 4 p.

  研究成果: Article › 査読

  • Medetomidine 100%
  • detomidine 92%
  • atipamezole 86%
  • Midazolam 81%
  • Atmospheric Pressure 75%
  27 被引用数 (Scopus)

• Effects of some diethylstilbestrol metabolites and analogs on cytotoxicity and aneuploidy induction in chinese hamster V79 cells

  Oda, T., Watanuki, M., Sakakibara, Y. & Sato, Y., 1995 1月 1, In: Biological and Pharmaceutical Bulletin. 18, 10, p. 1435-1438 4 p.

  研究成果: Article › 査読

  Open Access

  • Dienestrol 100%
  • Ethers 81%
  • Diethylstilbestrol 72%
  • dimestrol 60%
  • indenestrol 58%
  4 被引用数 (Scopus)

• Expression of Choline Acetyltransferase mRNA and Protein in T-Lymphocytes

  Fujii, T., Yamada, S., Tajima, S., Fujimoto, K., Suzuki, T., Kawashima, K. & MlSAWA, H., 1995, In: Proceedings of the Japan Academy, Series B. 71, 7, p. 231-235 5 p.

  研究成果: Article › 査読

  • choline 100%
  • acetylcholine 98%
  • choline acetyltransferase 92%
  • lymphocytes 88%
  • Choline O-Acetyltransferase 83%
  45 被引用数 (Scopus)

• Human MCAF Gene Transfer Enhances the Metastatic Capacity of a Mouse Cachectic Adenocarcinoma Cell Line in Vivo

  Nakashima, E., Mukaida, N., Kubota, Y., Kuno, K., Yasumoto, K., Ichimura, F., Nakanishi, I., Miyasaka, M. & Matsushima, K., 1995 11月, In: Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 12, 11, p. 1598-1604 7 p.

  研究成果: Article › 査読

  • Chemotactic 100%
  • Adenocarcinoma 58%
  • Cell Line 44%
  • Neoplasm Metastasis 38%
  • Genes 30%
  64 被引用数 (Scopus)

• Identification of Actin as a Substrate of ICE and an ICE-like Protease and Involvement of an ICE-like Protease but Not ICE in Vp-16-Induced U937 Apoptosis

  Mashima, T., Naito, M., Fujita, N., Noguchi, K. & Tsuruo, T., 1995, In: Biochemical and Biophysical Research Communications. 217, 3, p. 1185-1192 8 p.

  研究成果: Article › 査読

  • Caspase 1 100%
  • Antineoplastic Agent 72%
  • Actins 69%
  • Peptide Hydrolases 68%
  • Enzyme Activity 66%
  203 被引用数 (Scopus)

• Improved enzymatic procedure for a preparative-scale synthesis of sialic acid and KDN

  Sugai, T., Kuboki, A., Hiramatsu, S., Okazaki, H. & Ohta, H., 1995 12月 1, In: Bulletin of the Chemical Society of Japan. 68, 12, p. 3581-3589 9 p.

  研究成果: Article › 査読

  • N-Acetyl-D-Mannosamine 100%
  • Sialic Acid 80%
  • Pyruvic Acid 70%
  • Epimerization 42%
  • Pyruvate 37%
  42 被引用数 (Scopus)

• Isolation and characterization of inhibitory factors of DNA polymerase III holoenzyme from Escherichia coli

  Hase, M., Mizushima, T., Katayama, T. & Sekimizu, K., 1995 8月 1, In: FEMS microbiology letters. 130, 2-3, p. 215-220 6 p.

  研究成果: Article › 査読

  • DNA Polymerase III 100%
  • DNA Polymerase I 93%
  • Holoenzymes 88%
  • DNA-Directed DNA Polymerase 76%
  • Mono Q 53%

• Natural Estrogens Induce Modulation of Microtubules in Chinese Hamster V79 Cells in Culture

  Aizu-Yokota, E., Susaki, A. & Sato, Y., 1995 5月 1, In: Cancer Research. 55, 9, p. 1863-1868 6 p.

  研究成果: Article › 査読

  • Cricetulus 100%
  • Microtubules 91%
  • Estrogens 77%
  • Cell Culture Techniques 71%
  • 4-hydroxyestrone 26%
  35 被引用数 (Scopus)

• Nitric oxide mediates mitochondrial dysfunction in hepatoma cells induced by non‐activated Kupffer cells: Evidence implicating ICAM‐1‐dependent process

  KUROSE, IWAO., EBINUMA, HIROTOSHI., HIGUCHI, HAJIME., YONEI, YOSHIKAZU., SAITO, HIDETSUGU., KATO, SHINZO., MIURA, SOICHIRO. & ISHII, HIROMASA., 1995 9月, In: Journal of Gastroenterology and Hepatology. 10, 1 S, p. S68-S71

  研究成果: Article › 査読

  • Kupffer Cells 100%
  • Nitric Oxide 67%
  • Hepatocellular Carcinoma 66%
  • Rhodamine 123 37%
  • Fluorescence 33%
  17 被引用数 (Scopus)

• Phenotypes of dnaA mutants of escherichia coli sensitive to detergents and organic solvents

  Shinpuku, T., Mizushima, T., Guo, L., Miki, T. & Sekimizu, K., 1995 7月 6, In: Biochemical and Biophysical Research Communications. 212, 1, p. 84-89 6 p.

  研究成果: Article › 査読

  • Detergents 100%
  • Detergent 89%
  • Mutation 80%
  • Organic Solvent 70%
  • Escherichia coli 67%
  25 被引用数 (Scopus)

• Post-translational regulation of type I collagen synthesis by heparin in vascular smooth muscle cells

  Tajima, S., Wachi, H. & Takehan, M., 1995 2月, In: Journal of biochemistry. 117, 2, p. 353-358 6 p.

  研究成果: Article › 査読

  • Heparin 100%
  • Collagen Type I 97%
  • Vascular Smooth Muscle 95%
  • Collagen 91%
  • Smooth Muscle Myocytes 85%
  9 被引用数 (Scopus)

• Prodrugs of vitamin E. 1. Preparation and enzymatic hydrolysis of aminoalkanecarboxylic acid esters of d‐α‐tocopherol

  Takata, J., Karube, Y., Nagata, Y. & Matsushima, Y., 1995 1月, In: Journal of Pharmaceutical Sciences. 84, 1, p. 96-100 5 p.

  研究成果: Article › 査読

  • Vitamin E 100%
  • Prodrugs 92%
  • Enzymatic Hydrolysis 89%
  • Prodrug 88%
  • Esters 85%
  29 被引用数 (Scopus)

• Protective Effects of Glutathione Isopropyl Ester on the Sensitivity of Cultured Cells to UVB Irradiation

  Kobayashi, S., Satoh, H. & Takehana, M., 1995 1月 1, In: Biological and Pharmaceutical Bulletin. 18, 9, p. 1219-1222 4 p.

  研究成果: Article › 査読

  Open Access

  • glutathione monoisopropyl ester 100%
  • Glutathione 41%
  • Cultured Cells 39%
  • Protective 38%
  • Esters 35%
  5 被引用数 (Scopus)

• Quantitative relationship between structure and peritoneal membrane transport based on physiological pharmacokinetic concepts for acidic drugs

  Nakashima, E., Matsushita, R., Ohshima, T., Tsuji, A. & Ichimura, F., 1995 1月 1, In: Drug Metabolism and Disposition. 23, 11, p. 1220-1224 5 p.

  研究成果: Article › 査読

  • Physiological Phenomena 100%
  • Pharmacokinetics 72%
  • Membranes 57%
  • Drug 50%
  • Dialysis Solutions 44%
  9 被引用数 (Scopus)

• Reductive Conversion of Carbonyl Compounds by Yeast. Part II. Improved Conditions for the Production and Characterization of 1-Arylpropane-1,2-Diols and Related Compounds

  Mochizuki, N., Hiramatsu, S., Sugai, T., Ohta, H., Morita, H. & Itokawa, H., 1995, In: Bioscience, Biotechnology, and Biochemistry. 59, 12, p. 2282-2291 10 p.

  研究成果: Article › 査読

  • Pyruvate 100%
  • Benzaldehyde 92%
  • Carbonyl Compound 91%
  • Saccharomyces cerevisiae 88%
  • Yeasts 77%
  24 被引用数 (Scopus)

• Relationship between Cytotoxic and Microtubule Disruptive Activities of (+)-, (-)- and (±)-Indenestrol A and B Monomethyl Ethers in Chinese Hamster V79 Cells in Culture

  Oda, T., Aizu-Yokota, E., Kitaoka, M. & Sato, Y., 1995 1月 1, In: Biological and Pharmaceutical Bulletin. 18, 6, p. 818-824 7 p.

  研究成果: Article › 査読

  Open Access

  • indenestrol B 100%
  • indenestrol 98%
  • Ethers 68%
  • Methyl Ethers 52%
  • Cricetulus 46%
  4 被引用数 (Scopus)

• ROLE OF NITRIC OXIDE IN THE CONTROL OF BLOOD PRESSURE IN YOUNG AND ADULT SPONTANEOUSLY HYPERTENSIVE RATS

  Akiba, Y., Yamaguchi, N., Amano, H., Fujii, T., Fujimoto, K., Suzuki, T. & Kawashima, K., 1995 11月, In: Clinical and Experimental Pharmacology and Physiology. 22, p. S142-S143

  研究成果: Article › 査読

  • Inbred SHR Rats 100%
  • Nitroprusside 82%
  • Nitric Oxide 74%
  • Young Adult 74%
  • Blood Pressure 58%
  29 被引用数 (Scopus)

• Simultaneous determination of catecholamines, their basic metabolites and serotonin in urine by high‐performance liquid chromatography using A mixed‐mode column and an eight‐channel electrochemical detector

  Mashige, F., Matsushima, Y., Miyata, C., Yamada, R., Kanazawa, H., Sakuma, I., Takai, N., Shinozuka, N., Ohkubo, A. & Nakahara, K., 1995, In: Biomedical Chromatography. 9, 5, p. 221-225 5 p.

  研究成果: Article › 査読

  • Metanephrine 100%
  • Normetanephrine 99%
  • Catecholamine 72%
  • Serotonin 68%
  • Liquid Chromatography 64%
  49 被引用数 (Scopus)

• Species differences in the concentration of acetylcholine, a neurotransmitter, in whole blood and plasma

  Fujii, T., Yamada, S., Yamaguchi, N., Fujimoto, K., Suzuki, T. & Kawashima, K., 1995 12月 15, In: Neuroscience Letters. 201, 3, p. 207-210 4 p.

  研究成果: Article › 査読

  • Acetylcholine 100%
  • Neurotransmitter Agents 94%
  • Swine 47%
  • Goats 39%
  • Horses 34%
  45 被引用数 (Scopus)

• Studies on the active sites of Bacillus cereus sphingomyelinase substitution of some amino acids by site-directed mutagenesis

  Ikezawa, H., Tameishi, K., Yamada, A., Tamura, H., Tsukamoto, K., Matsuo, Y. & Nishikawa, K., 1995 9月, In: Amino Acids. 9, 3, p. 293-298 6 p.

  研究成果: Article › 査読

  • 4-nitrophenylphosphorylcholine 100%
  • Aspartic Acid Residue 68%
  • Sphingomyelin Phosphodiesterase 65%
  • Bacillus cereus 63%
  • Sphingomyelins 59%
  5 被引用数 (Scopus)

• Systematic approach to a dosage regimen for phenytoin based on one-point, steady-state plasma concentration

  Nakashima, E., Matsushita, R., Kido, H., Nakamura, M., Asahi, M. & Ichimura, F., 1995 2月, In: Therapeutic Drug Monitoring. 17, 1, p. 12-18 7 p.

  研究成果: Article › 査読

  • Phenytoin 100%
  • Bayes Theorem 21%
  • Population 20%
  • Datasets 13%
  • Pharmacokinetics 13%
  4 被引用数 (Scopus)
• 1996

  A candidate for cancer gene therapy: MIP-1α gene transfer to an adenocarcinoma cell line reduced tumorigenicity and induced protective immunity in immunocompetent mice

  Nakashima, E., Oya, A., Kubota, Y., Kanada, N., Matsushita, R., Takeda, K., Ichimura, F., Kuno, K., Mukaida, N., Hirose, K., Nakanishi, I., Ujiie, T. & Matsushima, K., 1996 12月 1, In: Pharmaceutical research. 13, 12, p. 1896-1901 6 p.

  研究成果: Article › 査読

  • Macrophage Inflammatory Proteins 100%
  • Neoplasm Genes 81%
  • Genetic Therapy 69%
  • Protective 62%
  • Immunity 61%
  65 被引用数 (Scopus)

• Acidic catecholamine metabolites and 5-hydroxyindoleacetic acid in urine: The influence of diet

  Mashige, F., Matsushima, Y., Kanazawa, H., Sakuma, I., Takai, N., Bessho, F. & Ohkubo, A., 1996, In: Annals of Clinical Biochemistry. 33, 1, p. 43-49 7 p.

  研究成果: Article › 査読

  • Vanillylmandelic Acid 100%
  • Vanillic Acid 96%
  • Hydroxyindoleacetic Acid 94%
  • Vanilmandelic Acid 92%
  • Catecholamine 86%
  31 被引用数 (Scopus)

• Action of nitrile hydratase from rhodococcus rhodochrous IFO 15564 on Derivatives of 2,5-Anhydro-d-allononitrile

  Yokoyama, M., Nakatsuka, Y., Sugai, T. & Ohta, H., 1996 1月, In: Bioscience, Biotechnology and Biochemistry. 60, 9, p. 1540-1542 3 p.

  研究成果: Article › 査読

  Open Access

  • nitrile hydratase 100%
  • Nitriles 84%
  • Rhodococcus 80%
  • Amides 63%
  • Hydroxyl Radical 58%
  7 被引用数 (Scopus)

• Biocatalytic approaches to both enantiomers of (2R*,3S*)-2-allyloxy-3,4,5,6-tetrahydro-2H-pyran-3-ol

  Sugai, T., Ikeda, H. & Ohta, H., 1996 6月 10, In: Tetrahedron. 52, 24, p. 8123-8134 12 p.

  研究成果: Article › 査読

  • Pyrans 100%
  • Lipase 67%
  • Acetylation 61%
  • Enantiomer 47%
  • Racemate 34%
  11 被引用数 (Scopus)

• Biocatalytic preparation of (R)-(-)-4-(phenylthio)-2-butanol and (R)-(-)-4-(Phenylsulfonyl)-2-butanol by the sequential use of Pichia farinosa and Rhodococcus rhodochrous

  Sugai, T., Ohtsuka, Y. & Ohta, H., 1996 1月 1, In: Chemistry Letters. 3, p. 233-234 2 p.

  研究成果: Article › 査読

  • Purity 100%
  • Reaction Yield 80%
  • Hydrogen Peroxide 76%
  • Reduction 45%
  • Oxidation Reaction 44%
  9 被引用数 (Scopus)

• Chromosome 22 complements apoptosis in Fas- and TNF-resistant mutant UK110 cells

  Noguchi, K., Naito, M., Kugoh, H., Oshimura, M., Mashima, T., Fujita, N., Yonehara, S. & Tsuruo, T., 1996 8月 10, In: Oncogene. 13, 1, p. 39-46 8 p.

  研究成果: Article › 査読

  • Chromosomes, Human, Pair 22 100%
  • Tumor Necrosis Factor Receptors 85%
  • Apoptosis 45%
  • Caspase 1 36%
  • Peptide Hydrolases 25%
  20 被引用数 (Scopus)

• Contribution of lysosomes to the subcellular distribution of basic drugs in the rat liver

  Ishizaki, J., Yokogawa, K., Hirano, M., Nakashima, E., Sai, Y., Ohkuma, S., Ohshima, T. & Ichimura, F., 1996, In: Pharmaceutical research. 13, 6, p. 902-906 5 p.

  研究成果: Article › 査読

  • Imipramine 100%
  • Lysosomes 88%
  • Biperiden 73%
  • Chlorpromazine 63%
  • Drug 45%
  36 被引用数 (Scopus)

• Effect of chronic ethanol feeding on kupffer cell-mediated antitumor cell activity

  Kato, S., Kurose, I., Higuchi, H., Ebinuma, H., Saito, H., Miura, S. & Ishii, H., 1996 1月 1, In: Alcoholism: Clinical and Experimental Research. 20, 1 SUPPL., p. 66A-68A

  研究成果: Article › 査読

  • Cell Activity 100%
  • Kupffer Cells 87%
  • Antitumor 67%
  • Ethanol 61%
  • Rhodamine 123 43%
  4 被引用数 (Scopus)

• Effect of ethanol on mouse hepatitis virus-induced cytotoxicity

  Saito, H., Masuda, T., Tashita, A., Ishiwata, Y., Yokochi, S., Mitani, T. & Ishii, H., 1996, In: Journal of gastroenterology. 31, 5, p. 679-683 5 p.

  研究成果: Article › 査読

  • Murine hepatitis virus 100%
  • Ethanol 58%
  • Alcohol Dehydrogenase 22%
  • aldehyde dehydrogenase (NAD(P)+) 14%
  • Microbial Viability 12%
  1 被引用数 (Scopus)

• Effect of Repeated Administration of KT3-671, a Nonpeptide AT₁ Receptor Antagonist, on Diurnal Variation in Blood Pressure, Heart Rate, and Locomotor Activity in Stroke-Prone Spontaneously Hypertensive Rats as Determined by Radiotelemetry

  Kawashima, K., Amano, H., Fujimoto, K., Suzuki, T., Fujii, T., Mochizuki, S. & Tomiyama, A., 1996 1月 1, In: Journal of Cardiovascular Pharmacology. 27, 3, p. 411-416 6 p.

  研究成果: Article › 査読

  • KT3 671 100%
  • Inbred SHR Rats 47%
  • Locomotion 42%
  • Heart Rate 32%
  • Stroke 30%
  11 被引用数 (Scopus)

• Effect on DNA topology by DnaA protein, the initiation factor of chromosomal DNA replication in Escherichia coli

  Mizushima, T., Katayama, T. & Sekimizu, K., 1996 9月 22, In: Biochemistry. 35, 35, p. 11512-11516 5 p.

  研究成果: Article › 査読

  • Peptide Initiation Factors 100%
  • DNA Replication 78%
  • Escherichia coli 54%
  • DNA 43%
  • Protein 32%
  20 被引用数 (Scopus)

• Efficient Lipase-catalyzed Preparation of Long-chain Fatty Acid Esters of Bile Acids: Biological Activity and Synthetic Application of the Products

  Sugai, T., Takizawa, M., Bakke, M., Ohtsuka, Y. & Oht, H., 1996 1月, In: Bioscience, Biotechnology and Biochemistry. 60, 12, p. 2059-2063 5 p.

  研究成果: Article › 査読

  Open Access

  • methyl cholate 100%
  • Ursodeoxycholic Acid 64%
  • Cholate 58%
  • Fatty Acid Ester 53%
  • Long-Chain Fatty Acid 53%
  23 被引用数 (Scopus)

• Enantioselective distribution behavior of (±)-pindolol in a liquid- liquid two-phase system containing optically active diol and boric acid

  Abe, Y., Qing, W., Shoji, T., Fukui, S., Suzuki, M., Kamiyama, T., Kobayashi, M. & Nishizawa, H., 1996 6月, In: Chemical and Pharmaceutical Bulletin. 44, 6, p. 1250-1251 2 p.

  研究成果: Article › 査読

  Open Access

  • hydrobenzoin 100%
  • threitol 78%
  • L-Threitol 74%
  • Hydrobenzoin 67%
  • boric acid 63%
  4 被引用数 (Scopus)

• Enantioseparation by dual-flow countercurrent extraction: Its application to the enantioseparation of (±)-propranolol

  Abe, Y., Shoji, T., Fukui, S., Sasamoto, M. & Nishizawa, H., 1996 8月, In: Chemical and Pharmaceutical Bulletin. 44, 8, p. 1521-1524 4 p.

  研究成果: Article › 査読

  Open Access

  • Boric Acid 100%
  • Propranolol 90%
  • Hydrochloride 81%
  • Chloroform 74%
  • boric acid 71%
  26 被引用数 (Scopus)

• Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C

  Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M. & Ishii, H., 1996 3月, In: Keio Journal of Medicine. 45, 1, p. 48-53 6 p.

  研究成果: Article › 査読

  Open Access

  • Liver Extracts 95%
  • Chronic Hepatitis C 73%
  • Interferons 64%
  • 2',5'-oligoadenylate 52%
  • Hepacivirus 48%
  9 被引用数 (Scopus)

• Estrogen receptor-mediated transcriptional activation by 17β-estradiol and its analogs

  Oda, T., Tsuchiya, T., Sato, Y. & Yasukochi, Y., 1996 8月, In: Biological and Pharmaceutical Bulletin. 19, 8, p. 1018-1022 5 p.

  研究成果: Article › 査読

  Open Access

  • Estradiol Congeners 100%
  • Estradiol Congener 77%
  • Estrogen 72%
  • Estrogen Receptors 63%
  • Transcriptional Activation 61%
  4 被引用数 (Scopus)

• Exchanges of polar amino acids to alanine generate platelet-activating factor receptor mutants with altered affinities to their ligand

  Ishii, I., Izuro, T., Ui, M. & Shimizii, T., 1996, In: FASEB Journal. 10, 6, p. A1099

  研究成果: Article › 査読

  • Polar Amino Acid 100%
  • platelet activating factor receptor 94%
  • Platelet Activating Factor 80%
  • Alanine 68%
  • Ligands 47%

• Glutathione isopropyl ester reduces UVB-induced skin damage in hairless mice

  Kobayashi, S., Takehana, M. & Tohyama, C., 1996 1月 1, In: Photochemistry and Photobiology. 63, 1, p. 106-110 5 p.

  研究成果: Article › 査読

  • glutathione monoisopropyl ester 100%
  • glutathione 71%
  • Hairless Mouse 63%
  • esters 52%
  • mice 48%
  25 被引用数 (Scopus)

• Growth phenotypes of Escherichia coli carrying a mutation of acidic phospholipid synthesis

  Akimitsu, N., Mizushima, T., Suzuki, E., Miki, T. & Sekimizu, K., 1996 10月, In: Biological and Pharmaceutical Bulletin. 19, 10, p. 1275-1278 4 p.

  研究成果: Article › 査読

  Open Access

  • Phosphatidylglycerol 100%
  • Phospholipids 68%
  • Mutation 64%
  • Phospholipid 64%
  • Escherichia coli 53%
  1 被引用数 (Scopus)

• Heat shock-induced DNA relaxation in vitro by DNA gyrase of Escherichia coli in the presence of ATP

  Kataoka, K., Mizushima, T., Ogata, Y., Miki, T. & Sekimizu, K., 1996, In: Journal of Biological Chemistry. 271, 40, p. 24806-24810 5 p.

  研究成果: Article › 査読

  • DNA Gyrase 100%
  • Heat-Shock Response 76%
  • Oxolinic Acid 53%
  • Adenosine Triphosphate 53%
  • Heat 50%
  26 被引用数 (Scopus)

• Immunohistochemical characterization of hepatic eosinophil cationic protein in primary biliary cirrhosis

  Miyaguchi, S., Oda, M., Mori, M., Imaeda, H., Tsuzuki, Y., Saito, H., Kamegaya, K. & Ishii, H., 1996 9月, In: International Hepatology Communications. 5, 4-5, p. 207-214 8 p.

  研究成果: Article › 査読

  • Eosinophil Cationic Protein 100%
  • Biliary Liver Cirrhosis 85%
  • Eosinophils 43%
  • Liver 36%
  • Chronic Hepatitis C 27%
  6 被引用数 (Scopus)

• Increase in synthesis and stability of σ³² on treatment with inhibitors of DNA gyrase in Escherichia coli

  Mizushima, T., Ohtsuka, Y., Mori, H., Miki, T. & Sekimizu, K., 1996 12月 13, In: Molecular Genetics and Genomics. 253, 3, p. 297-302 6 p.

  研究成果: Article › 査読

  • DNA Gyrase 100%
  • Topoisomerase II Inhibitors 98%
  • Nalidixic Acid 91%
  • Heat-Shock Proteins 72%
  • Escherichia coli 48%
  5 被引用数 (Scopus)