年別の研究成果
年別の研究成果
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Progressive accumulation of intrinsic mouse uromodulin in the kidneys of transgenic mice harboring the mutant human uromodulin gene
Takiue, Y., Hosoyamada, M., Yokoo, T., Kimura, M. & Shibasaki, T., 2008 3月, In: Biological and Pharmaceutical Bulletin. 31, 3, p. 405-411 7 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
Prognostic Value of Baseline Medications Plus Neutrophil-to-Lymphocyte Ratio in the Effectiveness of Nivolumab and Pembrolizumab in Patients With Advanced Non-Small-Cell Lung Cancer: A Retrospective Study
Ogiwara, T., Kawazoe, H., Egami, S., Hashimoto, H., Saito, Y., Sakiyama, N., Ohe, Y., Yamaguchi, M., Furukawa, T., Hara, A., Hiraga, Y., Jibiki, A., Yokoyama, Y., Suzuki, S. & Nakamura, T., 2021 11月 8, In: Frontiers in Oncology. 11, 770268.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Profiling of tumour-associated microbiota in human hepatocellular carcinoma
Komiyama, S., Yamada, T., Takemura, N., Kokudo, N., Hase, K. & Kawamura, Y. I., 2021 12月, In: Scientific reports. 11, 1, 10589.研究成果: Article › 査読
Open Access19 被引用数 (Scopus) -
Profile of the inhibitory effects of gefitinib in CYP2D6 variants in vitro
Semba, Y., Akiyoshi, T., Hibino, H., Imaoka, A. & Ohtani, H., 2020 10月, In: International journal of clinical pharmacology and therapeutics. 58, 10, p. 539-542 4 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Products of the reaction between α- or γ-tocopherol and nitrogen oxides analyzed by high-performance liquid chromatography with UV-visible and atmospheric pressure chemical ionization mass spectrometric detection
Nagata, Y., Matsumoto, Y. & Kanazawa, H., 2004 5月 21, In: Journal of Chromatography A. 1036, 2, p. 177-182 6 p.研究成果: Article › 査読
4 被引用数 (Scopus) -
Production of a reactive metabolite of troglitazone by electrochemical oxidation performed in nonaqueous medium
Tahara, K., Nishikawa, T., Hattori, Y., Iijima, S., Kouno, Y. & Abe, Y., 2009 12月 5, In: Journal of Pharmaceutical and Biomedical Analysis. 50, 5, p. 1030-1036 7 p.研究成果: Article › 査読
18 被引用数 (Scopus) -
Production and regulation of eotaxin-2/CCL24 in a differentiated human leukemic cell line, HT93
Yoshida, N., Aizu-Yokota, E., Sonoda, Y., Moriwaki, Y., Kishi, K. & Kasahara, T., 2007 10月, In: Biological and Pharmaceutical Bulletin. 30, 10, p. 1826-1832 7 p.研究成果: Article › 査読
5 被引用数 (Scopus) -
Production and characterization of transgenic mice harboring mutant human UMOD gene
Takiue, Y., Hosoyamada, M., Yokoo, T., Kimura, M., Ochiai, M., Kaneko, K., Ichida, K., Hosoya, T. & Shibasaki, T., 2008 6月, In: Nucleosides, Nucleotides and Nucleic Acids. 27, 6-7, p. 596-600 5 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
Prodrugs of vitamin E. 1. Preparation and enzymatic hydrolysis of aminoalkanecarboxylic acid esters of d‐α‐tocopherol
Takata, J., Karube, Y., Nagata, Y. & Matsushima, Y., 1995 1月, In: Journal of Pharmaceutical Sciences. 84, 1, p. 96-100 5 p.研究成果: Article › 査読
29 被引用数 (Scopus) -
Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity
Yamasaki, K., Iohara, D., Oyama, Y., Nishizaki, N., Kawazu, S., Nishi, K., Kadowaki, D., Taguchi, K., Otagiri, M. & Seo, H., 2020 3月 1, In: Journal of Pharmacy and Pharmacology. 72, 3, p. 356-363 8 p.研究成果: Article › 査読
3 被引用数 (Scopus) -
Process development with Bifunctional chiral epoxides to access single enantiomrs of pharmaceutical intermediates
Ikunaka, M. & Sugai, T., 2008 10月, In: Journal of Oil Palm Research. SPEC. ISS. OCTOBE, p. 143-158 16 p.研究成果: Article › 査読
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Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand
Moriwaki, Y., Watanabe, Y., Shinagawa, T., Kai, M., Miyazawa, M., Okuda, T., Kawashima, K., Yabashi, A., Waguri, S. & Misawa, H., 2009 8月, In: Neuroscience Research. 64, 4, p. 403-412 10 p.研究成果: Article › 査読
50 被引用数 (Scopus) -
Preventive effects of self-administered cryotherapy on paclitaxel-induced peripheral neuropathy in patients with early-stage breast cancer: A propensity score analysis
Shimanuki, Y., Hashimoto, H., Kawazoe, H., Uozumi, R., Udagawa, R., Watabe, D., Nakamura, T., Yamaguchi, M. & Terakado, H., 2021 6月, In: Pharmazie. 76, 6, p. 261-265 5 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Preventive Effects of Renin-angiotensin System Inhibitors on Oxaliplatin-induced Peripheral Neuropathy: A Retrospective Observational Study
Uchida, M., Kawazoe, H., Takatori, S., Namba, H., Uozumi, R., Tanaka, A., Kawasaki, H. & Araki, H., 2018 7月, In: Clinical Therapeutics. 40, 7, p. 1214-1222.e1研究成果: Article › 査読
13 被引用数 (Scopus) -
Prevention of postprandial hyperglycemia by ophthalmic nanoparticles based on protamine zinc insulin in the rabbit
Deguchi, S., Ogata, F., Isaka, T., Otake, H., Nakazawa, Y., Kawasaki, N. & Nagai, N., 2021 3月, In: Pharmaceutics. 13, 3, 375.研究成果: Article › 査読
Open Access -
Presynaptic M1 muscarinic receptor modulates spontaneous release of acetylcholine from rat basal forebrain slices
Suzuki, T., Fujimoto, K., Oohata, H. & Kawashima, K., 1988 1月 22, In: Neuroscience Letters. 84, 2, p. 209-212 4 p.研究成果: Article › 査読
51 被引用数 (Scopus) -
Presence of the factor that inhibits collagen synthesis and stimulates cell proliferation in developing embryonic chick skin extracts
Tajima, S., Ohyama, K., Tokimitsu, I. & Takehana, M., 1993 12月, In: Journal of Dermatological Science. 6, 3, p. 258-260 3 p.研究成果: Article › 査読
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Presence of a genistein-responsive inhibitory mechanism on interleukin-1αa-induced NF-κkB activation
Tago, K., Funakoshi, M., Mano, H., Yanagisawa, K., Hayakawa, M., Kuroiwa, K., Iwahana, H., Kasahara, T. & Tominaga, S. I., 2001, In: European Journal of Biochemistry. 268, 24, p. 6526-6533 8 p.研究成果: Article › 査読
7 被引用数 (Scopus) -
Presence of acetylcholine in blood of humans and rabbits
Kawashima, K., Oohata, H., Fujimoto, K. & Suzuki, T., 1990 1月 1, In: European journal of pharmacology. 183, 5, p. 2013-2014 2 p.研究成果: Article › 査読
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Presence of acetylcholine in blood and its localization in circulating mononuclear leukocytes of humans
Kawashima, K., Kajiyama, K., Fujimoto, K., Oohata, H. & Suzuki, T., 1993 1月 1, In: Biogenic Amines. 9, 4, p. 251-258 8 p.研究成果: Article › 査読
44 被引用数 (Scopus) -
Prescribing pattern of anti-parkinson drugs in Japan: A trend analysis from 2005 to 2010
Nakaoka, S., Ishizaki, T., Urushihara, H., Satoh, T., Ikeda, S., Yamamoto, M. & Nakayama, T., 2014 6月 6, In: PloS one. 9, 6, e99021.研究成果: Article › 査読
25 被引用数 (Scopus) -
Preparative-scale enzyme-catalyzed synthesis of (R)-α-fluorophenylacetic acid
Fukuyama, Y., Matoishi, K., Iwasaki, M., Takizawa, E., Miyazaki, M., Ohta, H., Hanzawa, S., Kakidani, H. & Sugai, T., 1999 1月 1, In: Bioscience, Biotechnology and Biochemistry. 63, 9, p. 1664-1666 3 p.研究成果: Article › 査読
Open Access13 被引用数 (Scopus) -
Preparative High-Performance Liquid Chromatography on Chemically Modified Porous Glass: Isolation of Saponins from Ginseng
Kanazawa, H., Nagata, Y., Matsushima, Y. & Tomoda, M., 1990, In: Chemical and Pharmaceutical Bulletin. 38, 6, p. 1630-1632 3 p.研究成果: Article › 査読
Open Access8 被引用数 (Scopus) -
Preparation of thermo-responsive polymer brushes on hydrophilic polymeric beads by surface-initiated atom transfer radical polymerization for a highly resolutive separation of peptides
Mizutani, A., Nagase, K., Kikuchi, A., Kanazawa, H., Akiyama, Y., Kobayashi, J., Annaka, M. & Okano, T., 2010 9月, In: Journal of Chromatography A. 1217, 38, p. 5978-5985 8 p.研究成果: Article › 査読
43 被引用数 (Scopus) -
Preparation of thermoresponsive cationic copolymer brush surfaces and application of the surface to separation of biomolecules
Nagase, K., Kobayashi, J., Kikuchi, A., Akiyama, Y., Kanazawa, H. & Okano, T., 2008 4月 1, In: Biomacromolecules. 9, 4, p. 1340-1347 8 p.研究成果: Article › 査読
116 被引用数 (Scopus) -
Preparation of thermoresponsive anionic copolymer brush surfaces for separating basic biomolecules
Nagase, K., Kobayashi, J., Kikuchi, A., Akiyama, Y., Kanazawa, H., Annaka, M. & Okano, T., 2010 1月 11, In: Biomacromolecules. 11, 1, p. 215-223 9 p.研究成果: Article › 査読
39 被引用数 (Scopus) -
Preparation of Sulfur-Containing Optically Active Secondary Alcohols Based on Pichia farinosa-Catalyzed anti-Prelog-Rule Reduction as the Key Step
Ohtsuka, Y., Katoh, O., Sugai, T. & Ohta, H., 1997 2月, In: Bulletin of the Chemical Society of Japan. 70, 2, p. 483-491 9 p.研究成果: Article › 査読
34 被引用数 (Scopus) -
Preparation of optically active α-hydroxy acid derivatives by microbial hydrolysis of cyanohydrins and its application to the synthesis of (R)-4-dodeeanolide
Kakeya, H., Sakai, N., Sugai, T. & Ohta, H., 1991 7月, In: Agricultural and biological chemistry. 55, 7, p. 1877-1881 5 p.研究成果: Article › 査読
32 被引用数 (Scopus) -
Preparation of Optically Active α-Hydroxy Acid Derivatives by Microbial Hydrolysis of Cyanohydrins and Its Application to the Synthesis of (R)-4-Dodecanolide†
Kakeya, H., Sakai, N., Sugai, T. & Ohta, H., 1991, In: Agricultural and biological chemistry. 55, 7, p. 1877-1881 5 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Preparation of Monomethyl Ether Derivatives of (+)-,(—)- and (±)-Indenestrols A and B
Oda, T. & Sato, Y., 1993 1月 1, In: Chemical and Pharmaceutical Bulletin. 41, 10, p. 1856-1859 4 p.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Preparation of methyl ursodeoxycholate via microbial reduction of methyl 7-ketolithocholate in an anaerobic interface bioreactor
Oda, S., Sugai, T. & Ohta, H., 2001 1月 1, In: Journal of Bioscience and Bioengineering. 91, 2, p. 202-207 6 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
Preparation of methyl ursodeoxycholate in an interface bioreactor: Use of a mixed solvent system to increase the solubilities of substrate and product
Oda, S., Sugai, T. & Ohta, H., 2001, In: Journal of Bioscience and Bioengineering. 92, 1, p. 86-88 3 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Preparation of menisdaurigenin and related compounds
Shirakawa, R., Ishikawa, S., Takahasi, M., Ueno, Y., Uekusa, Y., Narukawa, Y., Sugai, T. & Kiuchi, F., 2019 1月 25, In: Journal of Natural Medicines. 73, 1, p. 236-243 8 p.研究成果: Article › 査読
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Preparation of enantiomerically enriched compounds using enzymes; VII.1 A synthesis of Japanese beetle pheromone utilizing lipase-catalyzed enantioselective lactonization
Sugai, T., Ohsawa, S., Yamada, H. & Ohta, H., 1990, In: Synthesis (Germany). 1990, 12, p. 1112-1114 3 p.研究成果: Article › 査読
35 被引用数 (Scopus) -
Preparation of both enantiomers of methyl 3-benzoyloxypentanoate by enzyme-catalysed hydrolysis of corresponding racemic nitrile and amide
Yokoyama, M., Imai, N., Sugai, T. & Ohta, H., 1996 6月, In: Journal of Molecular Catalysis B: Enzymatic. 1, 3-6, p. 135-141 7 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
Preparation of (R)-3-hydroxy-n-methylpiperidine, a synthetic key intermediate of (R)-mepenzolate, based on the lipase-catalyzed resolution of the racemic form
Yamashita, Y., Hanaya, K., Shoji, M. & Sugai, T., 2017, In: Heterocycles. 95, 1, p. 370-379 10 p.研究成果: Article › 査読
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Preparation and characterization of a nanoparticulate formulation composed of PEG-PLA and PLA as anti-inflammatory agents
Ishihara, T., Takahashi, M., Higaki, M., Mizushima, Y. & Mizushima, T., 2010 1月 29, In: International Journal of Pharmaceutics. 385, 1-2, p. 170-175 6 p.研究成果: Article › 査読
44 被引用数 (Scopus) -
Preparation and antioxidant activity of α-pyridoin and its derivatives
Hatanaka, M., Takahashi, K., Nakamura, S. & Mashino, T., 2005 12月 15, In: Bioorganic and Medicinal Chemistry. 13, 24, p. 6763-6770 8 p.研究成果: Article › 査読
34 被引用数 (Scopus) -
Preparation and antioxidant/pro-oxidant activities of 3-monosubstituted 5-hydroxyoxindole derivatives
Yasuda, D., Takahashi, K., Ohe, T., Nakamura, S. & Mashino, T., 2016, In: Journal of Clinical Biochemistry and Nutrition. 59, 3, p. 165-173 9 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Preparation, Characterization, and in Vitro/in Vivo Evaluation of Paclitaxel-Bound Albumin-Encapsulated Liposomes for the Treatment of Pancreatic Cancer
Okamoto, Y., Taguchi, K., Sakuragi, M., Imoto, S., Yamasaki, K. & Otagiri, M., 2019 5月 17, In: ACS Omega. 4, 5, p. 8693-8700 8 p.研究成果: Article › 査読
Open Access18 被引用数 (Scopus) -
Preliminary study to identify the predictive factors for the response to methotrexate therapy in patients with rheumatoid arthritis
Inoue, S., Hashiguchi, M., Takagi, K., Kawai, S. & Mochizuki, M., 2009 7月, In: Yakugaku Zasshi. 129, 7, p. 843-849 7 p.研究成果: Article › 査読
19 被引用数 (Scopus) -
Pregnancy outcomes after exposure to tocilizumab: A retrospective analysis of 61 patients in Japan
Nakajima, K., Watanabe, O., Mochizuki, M., Nakasone, A., Ishizuka, N. & Murashima, A., 2016 9月 2, In: Modern rheumatology. 26, 5, p. 667-671 5 p.研究成果: Article › 査読
Open Access56 被引用数 (Scopus) -
Prediction of the extent and variation of grapefruit juice-drug interactions from the pharmacokinetic profile in the absence of grapefruit juice
Kogure, N., Akiyoshi, T., Imaoka, A. & Ohtani, H., 2014 10月 1, In: Biopharmaceutics and Drug Disposition. 35, 7, p. 373-381 9 p.研究成果: Article › 査読
5 被引用数 (Scopus) -
Prediction of deficiency-excess pattern in Japanese Kampo medicine: Multi-centre data collection
Maeda-Minami, A., Yoshino, T., Katayama, K., Horiba, Y., Hikiami, H., Shimada, Y., Namiki, T., Tahara, E., Minamizawa, K., Muramatsu, S., Yamaguchi, R., Imoto, S., Miyano, S., Mima, H., Mimura, M., Nakamura, T. & Watanabe, K., 2019 8月, In: Complementary Therapies in Medicine. 45, p. 228-233 6 p.研究成果: Article › 査読
5 被引用数 (Scopus) -
Prediction of changes in the clinical pharmacokinetics of basic drugs on the basis of octanol-water partition coefficients
Ishizaki, J., Yokogawa, K., Nakashima, E. & Ichimura, F., 1997 8月, In: Journal of Pharmacy and Pharmacology. 49, 8, p. 762-767 6 p.研究成果: Article › 査読
19 被引用数 (Scopus) -
Prediction Models for the 5- and 10-Year Incidence of Home Morning Hypertension: The Ohasama Study
Satoh, M., Metoki, H., Asayama, K., Kikuya, M., Murakami, T., Tatsumi, Y., Hara, A., Tsubota-Utsugi, M., Hirose, T., Inoue, R., Nomura, K., Hozawa, A., Imai, Y. & Ohkubo, T., 2022 4月 1, In: American journal of hypertension. 35, 4, p. 328-336 9 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Practical synthesis of the C-ring precursor of paclitaxel from 3-methoxytoluene
Fukaya, K., Yamaguchi, Y., Watanabe, A., Yamamoto, H., Sugai, T., Sugai, T., Sato, T. & Chida, N., 2016 4月 1, In: Journal of Antibiotics. 69, 4, p. 273-279 7 p.研究成果: Article › 査読
8 被引用数 (Scopus) -
Practical entry into the HIJKLM ring segment of ciguatoxin CTX3C
Oishi, T., Uehara, H., Nagumo, Y., Shoji, M., Le Brazidec, J. Y., Kosaka, M. & Hirama, M., 2001 2月 21, In: Chemical Communications. 4, p. 381-382 2 p.研究成果: Article › 査読
57 被引用数 (Scopus) -
PPARα Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates
Kamata, S., Oyama, T., Saito, K., Honda, A., Yamamoto, Y., Suda, K., Ishikawa, R., Itoh, T., Watanabe, Y., Shibata, T., Uchida, K., Suematsu, M. & Ishii, I., 2020 11月 20, In: iScience. 23, 11, 101727.研究成果: Article › 査読
Open Access23 被引用数 (Scopus) -
Potentiation of methylmercury toxicity by combined metal exposure: In vitro and in vivo models of a restricted metal exposome
Akiyama, M., Shinkai, Y., Yamakawa, H., Kim, Y. G. & Kumagai, Y., 2022 7月, In: Chemosphere. 299, 134374.研究成果: Article › 査読
1 被引用数 (Scopus)