検索結果
Kobayashi, R. ,
Huang, H. ,
Hamada, M. ,
Higashi, T. ,
Shoji, M. &
Sugai, T. ,
2012 9月 ,
In: Journal of Molecular Catalysis B: Enzymatic. 81 ,
p. 52-57 6 p. 研究成果: Article › 査読
Acylation
100%
vinyl acetate
83%
Lipases
79%
Isomers
76%
Burkholderia cepacia
75%
Hibino, H. ,
Makino, Y. ,
Sakiyama, N. ,
Makihara-Ando, R. ,
Hashimoto, H. ,
Akiyoshi, T. ,
Imaoka, A. ,
Fujiwara, Y. ,
Ohe, Y. ,
Yamaguchi, M. &
Ohtani, H. ,
2021 4月 ,
In: International journal of clinical pharmacology and therapeutics. 59 ,
4 ,
p. 328-332 5 p. 研究成果: Article › 査読
Aprepitant
100%
Amlodipine
86%
Atrioventricular Block
78%
Lung Neoplasms
52%
Drug Interactions
26%
Oda, T. ,
Sato, Y. ,
Kodam, M. &
Saito, H. ,
1990 1月 1 ,
In: Chemical and Pharmaceutical Bulletin. 38 ,
9 ,
p. 2397-2399 3 p. 研究成果: Article › 査読
Methyl Ethers
100%
Deuterium
87%
Diethylstilbestrol
86%
2H NMR Spectroscopy
77%
Diethylstilbestrol Monomethyl Ether
68%
Yonel, Y. ,
Kurose, I. ,
Fukumura, D. ,
Saito, H. ,
Miura, S. ,
Tsukada, N. ,
Oda, M. &
Tsuchiya, M. ,
1994 2月 ,
In: Liver. 14 ,
1 ,
p. 37-44 8 p. 研究成果: Article › 査読
Kupffer Cells
100%
Coculture Techniques
82%
Colonic Neoplasms
75%
Propidium
27%
Neoplasms
19%
Mine, T. ,
Morita, Y. ,
Kataoka, A. ,
Mizushima, T. &
Tsuchiya, T. ,
1998 7月 ,
In: Journal of biochemistry. 124 ,
1 ,
p. 187-193 7 p. 研究成果: Article › 査読
Antiporters
100%
Chloramphenicol
84%
Ion Transport
82%
Ethidium
71%
Escherichia coli
49%
Son, K. ,
Ueda, M. ,
Taguchi, K. ,
Maruyama, T. ,
Takeoka, S. &
Ito, Y. ,
2020 6月 10 ,
In: Journal of Controlled Release. 322 ,
p. 209-216 8 p. 研究成果: Article › 査読
polysarcosine
100%
Polyethylene Glycols
49%
Clearance
48%
Liposomes
43%
Liposome
41%
Ishihara, T. ,
Maeda, T. ,
Sakamoto, H. ,
Takasaki, N. ,
Shigyo, M. ,
Ishida, T. ,
Kiwada, H. ,
Mizushima, Y. &
Mizushima, T. ,
2010 10月 11 ,
In: Biomacromolecules. 11 ,
10 ,
p. 2700-2706 7 p. 研究成果: Article › 査読
Clearance
100%
Nanoparticles
90%
Polyethylene glycols
89%
Blood
85%
Polymers
82%
Ando, G. ,
Taguchi, K. ,
Enoki, Y. ,
Yokoyama, Y. ,
Kizu, J. &
Matsumoto, K. ,
2019 ,
In: Biological and Pharmaceutical Bulletin. 42 ,
11 ,
p. 1799-1804 6 p. 研究成果: Article › 査読
Ganciclovir
100%
Drug-Related Side Effects and Adverse Reactions
74%
Databases
48%
Drug
42%
Time
28%
Nishimura, T. ,
Takanohashi, T. ,
Tomi, M. ,
Horikoshi, M. ,
Higuchi, K. ,
Sai, Y. &
Nakashima, E. ,
2013 9月 ,
In: Journal of Pharmaceutical Sciences. 102 ,
9 ,
p. 3356-3363 8 p. 研究成果: Article › 査読
Mitoxantrone
100%
Xenobiotic Agent
98%
Umbilicus
94%
Xenobiotics
93%
Clearance
92%
randomized clinical trials
100%
Functional Food
79%
learning
58%
Japan
52%
Learning
47%
Ebinuma, H. ,
Saito, H. ,
Komuta, M. ,
Ojiro, K. ,
Wakabayashi, K. ,
Usui, S. ,
Chu, P. S. ,
Umeda, R. ,
Ishibashi, Y. ,
Takayama, T. ,
Kikuchi, M. ,
Nakamoto, N. ,
Yamagishi, Y. ,
Kanai, T. ,
Ohkuma, K. ,
Sakamoto, M. &
Hibi, T. ,
2011 10月 ,
In: Journal of gastroenterology. 46 ,
10 ,
p. 1238-1248 11 p. 研究成果: Article › 査読
Elasticity Imaging Techniques
100%
Acoustics
82%
Liver Cirrhosis
76%
Radiation
61%
Liver
31%
Hibino, H. ,
Sakiyama, N. ,
Makino, Y. ,
Makihara-Ando, R. ,
Horinouchi, H. ,
Fujiwara, Y. ,
Kanda, S. ,
Goto, Y. ,
Yoshida, T. ,
Okuma, Y. ,
Shinno, Y. ,
Murakami, S. ,
Hashimoto, H. ,
Akiyoshi, T. ,
Imaoka, A. ,
Ohe, Y. ,
Yamaguchi, M. &
Ohtani, H. ,
2022 4月 ,
In: European Journal of Clinical Pharmacology. 78 ,
4 ,
p. 613-621 9 p. 研究成果: Article › 査読
Aprepitant
100%
Cytochrome P-450 CYP3A
76%
Dexamethasone
61%
Cisplatin
60%
Lung Neoplasms
52%
Tokuno, M. ,
Taguchi, K. ,
Sakai, H. ,
Ohtsuki, S. ,
Yamasaki, K. &
Otagiri, M. ,
2020 10月 ,
In: Drug Metabolism And Pharmacokinetics. 35 ,
5 ,
p. 417-424 8 p. 研究成果: Article › 査読
Blood Substitutes
100%
Hemorrhagic Shock
84%
Cytochrome P450
75%
Cytochrome P-450 Enzyme System
68%
Cytochrome
61%
Hashimoto, M. ,
Iketani, O. ,
Ichinose, N. ,
Enoki, Y. ,
Taguchi, K. ,
Uno, S. ,
Uwamino, Y. ,
Hasegawa, N. &
Matsumoto, K. ,
2019 9月 ,
In: Journal of Infection and Chemotherapy. 25 ,
9 ,
p. 735-737 3 p. 研究成果: Article › 査読
Vancomycin
100%
Body Mass Index
48%
Obesity
18%
Body Weight
9%
pricing
100%
drug
68%
Costs and Cost Analysis
62%
market
56%
pharmaceutical market
49%
Murakami, Y. ,
Yamagoe, S. ,
Noguchi, K. ,
Takebe, Y. ,
Takahashi, N. ,
Uehara, Y. &
Fukazawa, H. ,
2006 9月 22 ,
In: Journal of Biological Chemistry. 281 ,
38 ,
p. 28113-28121 9 p. 研究成果: Article › 査読
latency-associated nuclear antigen
100%
Human Herpesvirus 8
75%
Vascular Endothelial Growth Factor Receptor
70%
Antigen
49%
Vascular Endothelial Growth Factor Receptor-1
21%
Matsuzaki, J. ,
Suzuki, H. ,
Asakura, K. ,
Saito, Y. ,
Hirata, K. ,
Takebayashi, T. &
Hibi, T. ,
2011 3月 ,
In: Journal of gastroenterology. 46 ,
3 ,
p. 332-338 7 p. 研究成果: Article › 査読
Barrett Esophagus
100%
Metaplasia
90%
Gallstones
39%
Atrophy
30%
Stomach
25%
Oda, K. ,
Nishimura, T. ,
Higuchi, K. ,
Ishido, N. ,
Ochi, K. ,
Iizasa, H. ,
Sai, Y. ,
Tomi, M. &
Nakashima, E. ,
2013 9月 ,
In: Journal of Pharmaceutical Sciences. 102 ,
9 ,
p. 3364-3372 9 p. 研究成果: Article › 査読
Mitoxantrone
100%
Trophoblasts
74%
Estrogen
73%
Estrogen Receptors
63%
Demethylation
26%
Oda, T. ,
Tsuchiya, T. ,
Sato, Y. &
Yasukochi, Y. ,
1996 8月 ,
In: Biological and Pharmaceutical Bulletin. 19 ,
8 ,
p. 1018-1022 5 p. 研究成果: Article › 査読
Estradiol Congeners
100%
Estradiol Congener
77%
Estrogen
72%
Estrogen Receptors
63%
Transcriptional Activation
61%
Mutoh, K. ,
Tsukahara, S. ,
Mitsuhashi, J. ,
Katayama, K. &
Sugimoto, Y. ,
2006 11月 ,
In: Cancer science. 97 ,
11 ,
p. 1198-1204 7 p. 研究成果: Article › 査読
MDR Genes
100%
ATP Binding Cassette Transporter, Subfamily B, Member 1
79%
Estradiol
63%
Estrogens
59%
Down-Regulation
50%
Imai, Y. ,
Ishikawa, E. ,
Asada, S. &
Sugimoto, Y. ,
2005 1月 15 ,
In: Cancer Research. 65 ,
2 ,
p. 596-604 9 p. 研究成果: Article › 査読
ATP Binding Cassette Transporter, Subfamily G, Member 2
100%
Estrogens
53%
Down-Regulation
45%
Breast Neoplasms
41%
Proteins
22%
Bioavailability
100%
Biological Availability
92%
Clinical Studies
71%
Clearance
63%
Drug
46%
Saito, Y. ,
Muramatsu, T. ,
Kanai, Y. ,
Ojima, H. ,
Sukeda, A. ,
Hiraoka, N. ,
Arai, E. ,
Sugiyama, Y. ,
Matsuzaki, J. ,
Uchida, R. ,
Yoshikawa, N. ,
Furukawa, R. &
Saito, H. ,
2019 4月 23 ,
In: Cell Reports. 27 ,
4 ,
p. 1265-1276.e4 研究成果: Article › 査読
Organoids
100%
Preclinical Drug Evaluations
90%
Biliary Tract
84%
Amorolfine
51%
Fenticonazole
50%
Yamada, T. ,
Nanashima, N. ,
Shimizu, T. ,
Nakazawa, Y. ,
Nakazawa, M. &
Tsuchida, S. ,
2015 10月 15 ,
In: Biochemical Journal. 471 ,
2 ,
p. 293-305 13 p. 研究成果: Article › 査読
Gene Rearrangement
100%
Retinal
98%
Retinal Detachment
92%
Lenses
80%
Thickening
53%
Biliary Tract Neoplasms
100%
Organoids
92%
Pancreatic Neoplasms
66%
Neoplasms
16%
Preclinical Drug Evaluations
11%
Saito, H. ,
Morizane, T. ,
Matsumoto, S. ,
Iwabuchi, N. ,
Satoh, I. ,
Oda, M. ,
Tsuchiya, M. ,
Watanabe, T. &
Tsuzuki, T. ,
1988 1月 1 ,
In: Nippon Shokakibyo Gakkai Zasshi. 85 ,
9 ,
p. 1664-1671 8 p. 研究成果: Article › 査読
Hepatocellular Carcinoma
100%
Carcinoma
82%
Cell Line
73%
T-Lymphocytes
34%
Chromosomes
17%
Organoids
100%
Biliary Tract
84%
Carcinoma
50%
Drug
40%
Neoplasms
16%
López-Vicario, C. ,
Sebastián, D. ,
Casulleras, M. ,
Duran-Güell, M. ,
Flores-Costa, R. ,
Aguilar, F. ,
Lozano, J. J. ,
Zhang, I. W. ,
Titos, E. ,
Kang, J. X. ,
Zorzano, A. ,
Arita, M. &
Clària, J. ,
2023 4月 ,
In: Hepatology. 77 ,
4 ,
p. 1303-1318 16 p. 研究成果: Article › 査読
Autacoids
100%
Fatty Liver
69%
Liver Diseases
54%
Fats
48%
Lipids
42%
Inoue, S. ,
Hashiguchi, M. ,
Kawai, S. &
Mochizuki, M. ,
2009 8月 ,
In: Yakugaku Zasshi. 129 ,
8 ,
p. 1001-1005 5 p. 研究成果: Article › 査読
methotrexate polyglutamate
100%
Fluorescence Polarization Immunoassay
87%
Methotrexate
71%
Physiologic Monitoring
60%
Immunoassay
54%
Obata, Y. ,
Kimura, S. ,
Nakato, G. ,
Iizuka, K. ,
Miyagawa, Y. ,
Nakamura, Y. ,
Furusawa, Y. ,
Sugiyama, M. ,
Suzuki, K. ,
Ebisawa, M. ,
Fujimura, Y. ,
Yoshida, H. ,
Iwanaga, T. ,
Hase, K. &
Ohno, H. ,
2014 12月 1 ,
In: EMBO Reports. 15 ,
12 ,
p. 1297-1304 8 p. 研究成果: Article › 査読
Lymphoid Tissue
100%
Epithelium
70%
Stromal Cells
62%
Cell Differentiation
50%
Epithelial Cells
44%
Molybdic Acid
100%
Molybdenum
90%
Aldose
81%
Epimerization
74%
Epimer
73%
Uchida, R. ,
Saito, Y. ,
Nogami, K. ,
Kajiyama, Y. ,
Suzuki, Y. ,
Kawase, Y. ,
Nakaoka, T. ,
Muramatsu, T. ,
Kimura, M. &
Saito, H. ,
2019 12月 1 ,
In: npj Aging and Mechanisms of Disease. 5 ,
1 , 1.
研究成果: Article › 査読
Organoids
100%
Epigenomics
66%
Nicotinamide Mononucleotide
43%
Stem Cells
28%
Cellular Senescence
27%
Saito, Y. ,
Saito, H. ,
Liang, G. &
Friedman, J. M. ,
2014 10月 1 ,
In: Clinical reviews in allergy & immunology. 47 ,
2 ,
p. 128-135 8 p. 研究成果: Article › 査読
Epigenomics
100%
Autoimmune Diseases
99%
MicroRNAs
96%
DNA Methylation
48%
Chromatin
43%
1-naphthol
100%
(-)-Epigallocatechin
82%
1-Naphthol
80%
epigallocatechin gallate
77%
Gallate
72%
Ogawa, M. ,
Ishihara, T. ,
Isobe, Y. ,
Kato, T. ,
Kuba, K. ,
Imai, Y. ,
Uchino, Y. ,
Tsubota, K. &
Arita, M. ,
2020 9月 1 ,
In: FASEB Journal. 34 ,
9 ,
p. 12492-12501 10 p. 研究成果: Article › 査読
12-15-lipoxygenase
100%
Eosinophils
57%
Lipoxin A4
54%
Wound Healing
52%
Lipid
41%
Konegawa, T. ,
Ohtsuka, Y. ,
Ikeda, H. ,
Sugai, T. &
Ohta, H. ,
1997 ,
In: Synlett. 1997 ,
11 ,
p. 1297-1299 3 p. 研究成果: Article › 査読
Acetylation
100%
Enantiomer
77%
Block Like Crystal
66%
Hydrolysis
61%
Hamada, M. ,
Inami, Y. ,
Nagai, Y. ,
Higashi, T. ,
Shoji, M. ,
Ogawa, S. ,
Umezawa, K. &
Sugai, T. ,
2009 9月 23 ,
In: Tetrahedron Asymmetry. 20 ,
18 ,
p. 2105-2111 7 p. 研究成果: Article › 査読
octanes
100%
Enzymes
89%
esters
88%
Esters
85%
enzymes
83%
Kurokawa, M. ,
Shindo, T. ,
Suzuki, M. ,
Nakajima, N. ,
Ishihara, K. &
Sugai, T. ,
2003 5月 16 ,
In: Tetrahedron Asymmetry. 14 ,
10 ,
p. 1323-1333 11 p. 研究成果: Article › 査読
Enzymes
100%
esters
98%
Esters
95%
enzymes
92%
Enantiomers
76%
Kuboki, A. ,
Bakke, M. ,
Sekiguchi, T. ,
Ohta, H. &
Sugai, T. ,
1998 6月 ,
In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 56 ,
6 ,
p. 489-499 11 p. 研究成果: Article › 査読
Sialic Acid
100%
Carbohydrate
75%
N-Acetyl-D-Glucosamine
66%
Ceramide
55%
Acetylation
45%
Benzyloxy Group
100%
Pheromone
77%
Ester
75%
Acid
42%
Application
38%
Ohta, H. ,
Kimura, Y. ,
Sugano, Y. &
Sugai, T. ,
1989 ,
In: Tetrahedron. 45 ,
17 ,
p. 5469-5476 8 p. 研究成果: Article › 査読
frontalin
100%
cyanohydrin
82%
Cyanohydrin
52%
Acetates
39%
Kinetics
28%
Hara, Y. ,
Sugata, S. ,
Kono, A. &
Tanaka, M. ,
1983 ,
In: Japanese Journal of Cancer and Chemotherapy. 10 ,
6 ,
p. 1511-1517 7 p. 研究成果: Article › 査読
Aoki, H. ,
Isobe, Y. ,
Yoshida, M. ,
Kang, J. X. ,
Maekawa, M. &
Arita, M. ,
2023 3月 ,
In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1868 ,
3 , 159275.
研究成果: Article › 査読
docosapentaenoic acid
100%
Docosahexaenoic Acids
74%
Crowns
68%
Non-alcoholic Fatty Liver Disease
67%
G-Protein-Coupled Receptors
63%
Fukuhara, S. ,
Masaoka, T. ,
Nishimura, S. ,
Nakamura, M. ,
Matsuzaki, J. ,
Tsugawa, H. ,
Miyoshi, S. ,
Mori, H. ,
Kawase, S. ,
Shibata, S. ,
Okano, H. ,
Kanai, T. &
Suzuki, H. ,
2017 12月 1 ,
In: Digestive Diseases and Sciences. 62 ,
12 ,
p. 3359-3369 11 p. 研究成果: Article › 査読
Gastric Emptying
100%
Apolipoproteins E
92%
Neuroglia
77%
Knockout Mice
44%
Glial Fibrillary Acidic Protein
43%
Saito, H. ,
Ebinuma, H. ,
Tada, S. ,
Tsunematsu, S. ,
Atsukawa, K. ,
Masuda, T. ,
Tsuchiya, M. &
Ishii, H. ,
1996 3月 ,
In: Keio Journal of Medicine. 45 ,
1 ,
p. 48-53 6 p. 研究成果: Article › 査読
Liver Extracts
95%
Chronic Hepatitis C
73%
Interferons
64%
2',5'-oligoadenylate
52%
Hepacivirus
48%
Nishimura, T. ,
Seki, Y. ,
Sato, K. ,
Chishu, T. ,
Kose, N. ,
Terasaki, T. ,
Kang, Y. S. ,
Sai, Y. &
Nakashima, E. ,
2008 10月 ,
In: Drug Metabolism and Disposition. 36 ,
10 ,
p. 2080-2085 6 p. 研究成果: Article › 査読
Dehydroepiandrosterone Sulfate
100%
Zidovudine
92%
Trophoblasts
67%
Cell Line
36%
Dehydroepiandrosterone
10%
Nishimura, T. ,
Tanaka, J. ,
Tomi, M. ,
Seki, Y. ,
Kose, N. ,
Sai, Y. &
Nakashima, E. ,
2011 9月 ,
In: Journal of Pharmaceutical Sciences. 100 ,
9 ,
p. 3959-3967 9 p. 研究成果: Article › 査読
Dehydroepiandrosterone Sulfate
100%
Zidovudine
92%
Nucleosides
27%
Antiretroviral
25%
Ethylisopropylamiloride
17%