年別の研究成果
年別の研究成果
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Direct proline-catalyzed asymmetric α-aminoxylation of aldehydes and ketones
Hayashi, Y., Yamaguchi, J., Sumiya, T., Hibino, K. & Shoji, M., 2004 9月 3, In: Journal of Organic Chemistry. 69, 18, p. 5966-5973 8 p.研究成果: Article › 査読
148 被引用数 (Scopus) -
Direct determination of acetylcholine release by radioimmunoassay and presence of presynaptic M1 muscarinic receptors in guinea pig ileum
Kawashima, K., Fujimoto, K., Suzuki, T. & Oohata, H., 1988 1月 1, In: Journal of Pharmacology and Experimental Therapeutics. 244, 3, p. 1036-1039 4 p.研究成果: Article › 査読
25 被引用数 (Scopus) -
Diphenylprolinol silyl ethers as efficient organocatalysts for the asymmetric Michael reaction of aldehydes and nitroalkenes
Hayashi, Y., Gotoh, H., Hayashi, T. & Shoji, M., 2005 7月 4, In: Angewandte Chemie - International Edition. 44, 27, p. 4212-4215 4 p.研究成果: Article › 査読
1130 被引用数 (Scopus) -
Diminished antigen-specific IgG1 and interleukin-6 production and acetylcholinesterase expression in combined M1 and M5 muscarinic acetylcholine receptor knockout mice
Fujii, Y. X., Tashiro, A., Arimoto, K., Fujigaya, H., Moriwaki, Y., Misawa, H., Fujii, T., Matsui, M., Kasahara, T. & Kawashima, K., 2007 8月, In: Journal of Neuroimmunology. 188, 1-2, p. 80-85 6 p.研究成果: Article › 査読
42 被引用数 (Scopus) -
Digoxin absorption decreased independently of P-gp activity in rats with irinotecan-induced gastrointestinal damage
Tsuchitani, T., Akiyoshi, T., Imaoka, A. & Ohtani, H., 2021 12月, In: Journal of Pharmaceutical Health Care and Sciences. 7, 1, 24.研究成果: Article › 査読
Open Access -
Different Reaction Modes for the Oxidative Dimerization of Epoxyquinols and Epoxyquinones. Importance of Intermolecular Hydrogen-Bonding
Shoji, M., Imai, H., Shiina, I., Kakeya, H., Osada, H. & Hayashi, Y., 2004 3月 5, In: Journal of Organic Chemistry. 69, 5, p. 1548-1556 9 p.研究成果: Article › 査読
35 被引用数 (Scopus) -
Different intra-cerebrospinal distribution of linezolid in patients with inflammatory meningitis
Ichinose, N., Yoshikawa, G., Fukao, E., Ichisawa, M., Takahata, T., Enoki, Y., Taguchi, K., Oda, T., Tsutsumi, K. & Matsumoto, K., 2021 9月, In: International Journal of Infectious Diseases. 110, p. 382-384 3 p.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Differential roles of NF-Y transcription factor in ER chaperone expression and neuronal maintenance in the CNS
Yamanaka, T., Tosaki, A., Miyazaki, H., Kurosawa, M., Koike, M., Uchiyama, Y., Maity, S. N., Misawa, H., Takahashi, R., Shimogori, T., Hattori, N. & Nukina, N., 2016 9月 30, In: Scientific reports. 6, 34575.研究成果: Article › 査読
Open Access8 被引用数 (Scopus) -
Differential regulation of eotaxin-1/CCL11 and eotaxin-3/CCL26 production by the TNF-α and IL-4 stimulated human lung fibroblast
Rokudai, A., Terui, Y., Kuniyoshi, R., Mishima, Y., Mishima, Y., Aizu-Yokota, E., Sonoda, Y., Kasahara, T. & Hatake, K., 2006 6月, In: Biological and Pharmaceutical Bulletin. 29, 6, p. 1102-1109 8 p.研究成果: Article › 査読
30 被引用数 (Scopus) -
Differential involvement of p38 mitogen-activated protein kinase and phosphatidyl inositol 3-kinase in the IL-1-mediated NF-κB and AP-1 activation
Funakoshi, M., Sonoda, Y., Tago, K., Tominaga, S. I. & Kasahara, T., 2001, In: International Immunopharmacology. 1, 3, p. 595-604 10 p.研究成果: Article › 査読
33 被引用数 (Scopus) -
Differential inhibition by staurosporine, a potent protein kinase C inhibitior, of 12-o-tetradecanoylphorbol-13-acetate-caused skin tumor promotion, epidermal ornithine decarboxylase induction, hyperplasia and inflammation
Yamamoto, S., Kiyoto, I., Aizu, E., Nakadate, T., Hosoda, Y. & Kato, R., 1989 7月, In: Carcinogenesis. 10, 7, p. 1315-1322 8 p.研究成果: Article › 査読
51 被引用数 (Scopus) -
Differential induction of JE/MCP-1 in subclones from a murine macrophage cell line, raw 264.7: Role of -B-3 binding protein
Ueno, M., Sonoda, Y., Funakoshi, M., Mukaida, N., Nose, K. & Kasahara, T., 2000 3月, In: Cytokine. 12, 3, p. 207-219 13 p.研究成果: Article › 査読
14 被引用数 (Scopus) -
Differential induction of cystathionine γ-lyase in the livers and kidneys of mouse dams during gestation and lactation
Akahoshi, N., Izumi, T., Ishizaki, Y. & Ishii, I., 2006, In: Biological and Pharmaceutical Bulletin. 29, 9, p. 1799-1802 4 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
Differential expression of ezrin and CLP36 in the two layers of syncytiotrophoblast in rats
Higuchi, K., Iizasa, H., Sai, Y., Horieya, S., Lee, K. E., Wada, M., Deguchi, M., Nishimura, T., Wakayama, T., Tamura, A., Tsukita, S., Kose, N., Kang, Y. S. & Nakashima, E., 2010, In: Biological and Pharmaceutical Bulletin. 33, 8, p. 1400-1406 7 p.研究成果: Article › 査読
7 被引用数 (Scopus) -
Differential effects of various skin tumor-promoting agents on prostaglandin E2 release from primary cultures of mouse epidermal cells
Eriko Aizu, A., Satoshi Yamamoto, Y., Teruo Nakadate, N. & Ryuichi Kato, K., 1990 6月 21, In: European journal of pharmacology. 182, 1, p. 19-28 10 p.研究成果: Article › 査読
28 被引用数 (Scopus) -
Differential effects of the ascorbyl and tocopheryl derivative on the methamphetamine-induced toxic behavior and toxicity
Ito, S., Mori, T., Kanazawa, H. & Sawaguchi, T., 2007 10月 30, In: Toxicology. 240, 1-2, p. 96-110 15 p.研究成果: Article › 査読
16 被引用数 (Scopus) -
Differential effects of diacylglycerols and 12-O-tetradecanoylphorbol-13-acetate on protein phosphorylation and cell proliferation of tumor promoter-dependent leukemia cell line A65T
Yamamoto, S., Gotoh, H., Aizu, E., Sasakawa, N., Hiai, H. & Kato, R., 1988 10月, In: Carcinogenesis. 9, 10, p. 1857-1862 6 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
Differences in Pharmacokinetic/Pharmacodynamic Parameters of Tedizolid Against VRE and MRSA
Liu, X., Tashiro, S., Igarashi, Y., Takemura, W., Kojima, N., Morita, T., Hayashi, M., Enoki, Y., Taguchi, K. & Matsumoto, K., 2023 1月, In: Pharmaceutical research. 40, 1, p. 187-196 10 p.研究成果: Article › 査読
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Differences in maximum tolerated doses and approval doses of molecularly targeted oncology drug between Japan and Western countries
Maeda, H. & Kurokawa, T., 2014 8月, In: Investigational new drugs. 32, 4, p. 661-669 9 p.研究成果: Article › 査読
16 被引用数 (Scopus) -
Differences in a single extracellular residue underlie adhesive functions of two zebrafish aqp0s
Vorontsova, I., Hall, J. E., Schilling, T. F., Nagai, N. & Nakazawa, Y., 2021 8月, In: Cells. 10, 8, 2005.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Dietary-protein sources modulate host susceptibility to Clostridioides difficile infection through the gut microbiota
Yakabe, K., Higashi, S., Akiyama, M., Mori, H., Murakami, T., Toyoda, A., Sugiyama, Y., Kishino, S., Okano, K., Hirayama, A., Gotoh, A., Li, S., Mori, T., Katayama, T., Ogawa, J., Fukuda, S., Hase, K. & Kim, Y. G., 2022 9月 13, In: Cell Reports. 40, 11, 111332.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Dienone-Phenol Rearrangement of (+ )-2,-Demethoxydehydrogriseofulvin into a 4-Methylxanthone Derivative
Oda, T., Yamaguchi, Y. & Sato, Y., 1986 1月 1, In: Chemical and Pharmaceutical Bulletin. 34, 2, p. 858-863 6 p.研究成果: Article › 査読
Open Access6 被引用数 (Scopus) -
Diclofenac protects cultured human corneal epithelial cells against hyperosmolarity and ameliorates corneal surface damage in a rat model of dry eye
Sawazaki, R., Ishihara, T., Usui, S., Hayashi, E., Tahara, K., Hoshino, T., Higuchi, A., Nakamura, S., Tsubota, K. & Mizushima, T., 2014 3月 27, In: Investigative Ophthalmology and Visual Science. 55, 4, p. 2547-2556 10 p.研究成果: Article › 査読
31 被引用数 (Scopus) -
Diastereoselective total synthesis of both enantiomers of epolactaene
Hayashi, Y., Kanayama, J., Yamaguchi, J. & Shoji, M., 2002 12月 27, In: Journal of Organic Chemistry. 67, 26, p. 9443-9448 6 p.研究成果: Article › 査読
41 被引用数 (Scopus) -
Diagnosing native liver fibrosis and esophageal varices using liver and spleen stiffness measurements in biliary atresia: a pilot study
Tomita, H., Ohkuma, K., Masugi, Y., Hosoe, N., Hoshino, K., Fuchimoto, Y., Fujino, A., Shimizu, T., Kato, M., Fujimura, T., Ishihama, H., Takahashi, N., Tanami, Y., Ebinuma, H., Saito, H., Sakamoto, M., Nakano, M. & Kuroda, T., 2016 9月 1, In: Pediatric Radiology. 46, 10, p. 1409-1417 9 p.研究成果: Article › 査読
21 被引用数 (Scopus) -
Dextran sulfate sodium inhibits amyloid-β oligomer binding to cellular prion protein
Aimi, T., Suzuki, K., Hoshino, T. & Mizushima, T., 2015 8月 1, In: Journal of Neurochemistry. 134, 4, p. 611-617 7 p.研究成果: Article › 査読
Open Access8 被引用数 (Scopus) -
Dexamethasone suppresses neurosteroid biosynthesis via downregulation of steroidogenic enzyme gene expression in human glioma GI-1 cells
Koibuchi, F., Ritoh, N., Aoyagi, R., Funakoshi-Tago, M. & Tamura, H., 2014 7月, In: Biological and Pharmaceutical Bulletin. 37, 7, p. 1241-1247 7 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Development of temperature-responsive chromatography using functional polymers
Ayano, E. & Kanazawa, H., 2005, In: BUNSEKI KAGAKU. 54, 7, p. 593-603 11 p.研究成果: Article › 査読
4 被引用数 (Scopus) -
Development of sustained-release ophthalmic formulation based on tranilast solid nanoparticles
Minami, M., Seiriki, R., Otake, H., Nakazawa, Y., Kanai, K., Tanino, T. & Nagai, N., 2020 4月 1, In: Materials. 13, 7, 1675.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Development of Risk Prediction Model for Grade 2 or Higher Hypocalcemia in Patients With Bone Metastasis Treated With Denosumab Plus Cholecalciferol (Vitamin D3)/Calcium Supplement
Ikegami, K., Hashiguchi, M., Kizaki, H., Yasumuro, O., Funakoshi, R. & Hori, S., 2022 9月, In: Journal of Clinical Pharmacology. 62, 9, p. 1151-1159 9 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Development of plasma ghrelin level as a novel marker for gastric mucosal atrophy after Helicobacter pylori eradication
Mori, H., Suzuki, H., Matsuzaki, J., Kameyama, K., Igarashi, K., Masaoka, T. & Kanai, T., 2022, In: Annals of Medicine. 54, 1, p. 170-180 11 p.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Development of p62-Keap1 protein–protein interaction inhibitors as doxorubicin-sensitizers against non-small cell lung cancer
Yasuda, D., Yoshida, I., Imamura, R., Katagishi, D., Takahashi, K., Kojima, H., Okabe, T., Ichimura, Y., Komatsu, M., Mashino, T. & Ohe, T., 2022 1月, In: Results in Chemistry. 4, 100609.研究成果: Article › 査読
Open Access -
Development of Novel Diclofenac Analogs Designed to Avoid Metabolic Activation and Hepatocyte Toxicity
Tateishi, Y., Ohe, T., Ogawa, M., Takahashi, K., Nakamura, S. & Mashino, T., 2020 12月 22, In: ACS Omega. 5, 50, p. 32608-32616 9 p.研究成果: Article › 査読
Open Access4 被引用数 (Scopus) -
Development of nanocarriers functionalized with stimuli-responsive polymer for controlled cellular uptake
Yamanouchi, T., Katsuyama, N., Hiruta, Y., Ayano, E. & Kanazawa, H., 2018 3月, In: KOBUNSHI RONBUNSHU. 75, 2, p. 116-127 12 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Development of lecithinized superoxide dismutase as a drug for IPF
Mizushima, T., 2013, In: Drug Delivery System. 28, 3, p. 221-228 8 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Development of lecithinized superoxide dismutase as a drug for IPF
Mizushima, T., 2014, In: Yakugaku Zasshi. 134, 1, p. 69-76 8 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Development of lecithinized superoxide dismutase
Mizushima, T., 2013 10月 31, In: Japanese Journal of Chest Diseases. 72, 10, p. 1094-1103 10 p.研究成果: Article › 査読
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Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signaling
Kanaya, T., Sakakibara, S., Jinnohara, T., Hachisuka, M., Tachibana, N., Hidano, S., Kobayashi, T., Kimura, S., Iwanaga, T., Nakagawa, T., Katsuno, T., Kato, N., Akiyama, T., Sato, T., Williams, I. R. & Ohno, H., 2018 2月 1, In: Journal of Experimental Medicine. 215, 2, p. 501-519 19 p.研究成果: Article › 査読
Open Access51 被引用数 (Scopus) -
Development of Indole Alkaloid-Type Dual Immune Checkpoint Inhibitors Against CTLA-4 and PD-L1 Based on Diversity-Enhanced Extracts
Suzuki, Y., Ichinohe, K., Sugawara, A., Kida, S., Murase, S., Zhang, J., Yamada, O., Hattori, T., Oshima, Y. & Kikuchi, H., 2021 11月 8, In: Frontiers in Chemistry. 9, 766107.研究成果: Article › 査読
Open Access3 被引用数 (Scopus) -
Development of HPLC with fluorescent detection using NBD-F for the quantification of colistin sulfate in rat plasma and its pharmacokinetic applications
Ouchi, S., Matsumoto, K., Okubo, M., Yokoyama, Y. & Kizu, J., 2018 5月 1, In: Biomedical Chromatography. 32, 5, e4167.研究成果: Article › 査読
5 被引用数 (Scopus) -
Development of fluorescent-labeled trapping reagents based on cysteine to detect soft and hard electrophilic reactive metabolites
Shibazaki, C., Ohe, T., Takahashi, K., Nakamura, S. & Mashino, T., 2021 8月, In: Drug Metabolism And Pharmacokinetics. 39, 100386.研究成果: Article › 査読
3 被引用数 (Scopus) -
Development of chromatography system organic solvent-free using multi-functional polymers
Nishio, T. & Kanazawa, H., 2010, In: BUNSEKI KAGAKU. 59, 3, p. 163-173 11 p.研究成果: Article › 査読
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Development of biodegradable nanoparticles for liver-specific ribavirin delivery
Ishihara, T., Kaneko, K., Ishihara, T. & Mizushima, T., 2014 12月, In: Journal of Pharmaceutical Sciences. 103, 12, p. 4005-4011 7 p.研究成果: Article › 査読
28 被引用数 (Scopus) -
Development of a sensitive LC–MS/MS method for quantification of linezolid and its primary metabolites in human serum
Souza, E., Felton, J., Crass, R. L., Hanaya, K. & Pai, M. P., 2020 1月 30, In: Journal of Pharmaceutical and Biomedical Analysis. 178, 112968.研究成果: Article › 査読
8 被引用数 (Scopus) -
Development of a pharmacokinetic model of transplacental transfer of metformin to predict in vivo fetal exposure
Kurosawa, K., Chiba, K., Noguchi, S., Nishimura, T. & Tomi, M., 2020 12月, In: Drug Metabolism and Disposition. 48, 12, p. 1293-1302 10 p.研究成果: Article › 査読
Open Access4 被引用数 (Scopus) -
Development of a novel sulfonate ester-based prodrug strategy
Hanaya, K., Yoshioka, S., Ariyasu, S., Aoki, S., Shoji, M. & Sugai, T., 2016 1月 15, In: Bioorganic and Medicinal Chemistry Letters. 26, 2, p. 545-550 6 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
Development of a novel microRNA promoter microarray for ChIP-on-chip assay to identify epigenetically regulated microRNAs
Saito, Y., Suzuki, H., Taya, T., Nishizawa, M., Tsugawa, H., Matsuzaki, J., Hirata, K., Saito, H. & Hibi, T., 2012 9月 14, In: Biochemical and Biophysical Research Communications. 426, 1, p. 33-37 5 p.研究成果: Article › 査読
17 被引用数 (Scopus) -
Development of a new scholastic program for medication counseling practice in preclinical training, constructed for junior students by senior students based on their experiences of on-site practice
Suzuki, S., Aono, I., Imai, N., Kuwabara, A., Kenda, Y., Matsumoto, M., Yoshida, A., Watanabe, A., Takagi, A., Kobayashi, N., Saeki, H., Ohtani, H., Nakamur, T. & Kizud, J., 2017, In: Yakugaku Zasshi. 137, 11, p. 1391-1408 18 p.研究成果: Article › 査読
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Development of an electronic medical record-based algorithm to identify patients with Stevens-Johnson syndrome and toxic epidermal necrolysis in Japan
Fukasawa, T., Takahashi, H., Kameyama, N., Fukuda, R., Furuhata, S., Tanemura, N., Amagai, M. & Urushihara, H., 2019 8月 1, In: PloS one. 14, 8, e0221130.研究成果: Article › 査読
Open Access5 被引用数 (Scopus) -
Development of a Fluorescent-Labeled Trapping Reagent to Detect Reactive Acyl Glucuronides
Shibazaki, C., Mashita, O., Takahashi, K., Nakamura, S., Mashino, T. & Ohe, T., 2021 11月 15, In: Chemical Research in Toxicology. 34, 11, p. 2343-2352 10 p.研究成果: Article › 査読
1 被引用数 (Scopus)