薬学部

Synthesis of methyl ursodeoxycholate via microbial reduction of methyl 7-ketolithocholate with Eubacterium aerofaciens JCM 7790 grown on two kinds of carbon and hydride sources, glucose and mannitol

Oda, S., Sugai, T. & Ohta, H., 2001 1月 1, In: Journal of Bioscience and Bioengineering. 91, 2, p. 178-183 6 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Synthesis of methylophiopogonanone a

Katagiri, R., Uekusa, Y., Narukawa, Y. & Kiuchi, F., 2020, In: Heterocycles. 100, 5, p. 803-808 6 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Synthesis of methyl epi-anhydroquinate utilizing [2,3]-sigmatropic rearrangement of iodosoalkene

Inomata, S., Ueda, M., Sugai, T. & Shoji, M., 2013, In: Chemistry Letters. 42, 10, p. 1273-1275 3 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of linezolid metabolites PNU-142300 and PNU-142586 toward the exploration of metabolite-related events

Hanaya, K., Matsumoto, K., Yokoyama, Y., Kizu, J., Shoji, M. & Sugai, T., 2017, In: Chemical and Pharmaceutical Bulletin. 65, 2, p. 194-199 6 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity

Yasuda, D., Nakajima, M., Yuasa, A., Obata, R., Takahashi, K., Ohe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Imamura, R., Kojima, H., Okabe, T., Nagano, T. & Mashino, T., 2016, In: Bioorganic and Medicinal Chemistry Letters. 26, 24, p. 5956-5959 4 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Synthesis of fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation

Tsunekawa, R., Hanaya, K., Higashibayashi, S. & Sugai, T., 2018, In: Bioscience, Biotechnology and Biochemistry. 82, 8, p. 1316-1322 7 p.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

Synthesis of enantiomers of indanoxazolidinone based on the lipase-catalyzed resolution of the corresponding N-carbamylamino derivative

Suzuki, M., Nagasawa, C. & Sugai, T., 2001 6月 4, In: Tetrahedron. 57, 23, p. 4841-4848 8 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Synthesis of enantiomerically enriched drug precursors and an insect pheromone via reduction of ketones using commercially available carbonyl reductase screening kit “Chiralscreen® OH”

Nagai, T., Sakurai, S., Natori, N., Hataoka, M., Kinoshita, T., Inoue, H., Hanaya, K., Shoji, M. & Sugai, T., 2018 4月 1, In: Bioorganic and Medicinal Chemistry. 26, 7, p. 1304-1313 10 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Synthesis of citronellyl acetate via a transacetylation to citronellol from acetyl coenzyme A produced from glucose and acetate in growing yeasts

Oda, S., Sugai, T. & Ohta, H., 2001, In: Chemistry Letters. 6, p. 500-501 2 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of bioactive sesquiterpene heliannuol E involving a ring-expansion reaction of spirodienones

Doi, F., Ogamino, T., Sugai, T. & Nishiyama, S., 2003, In: Synlett. 3, p. 411-413 3 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

Synthesis of benzyl tetra-O-acetyl-α-L-glucopyranoside from benzyl 2,3-dideoxy-β-D-Erythro-hex-2-enopyranoside

Okazaki, H., Ueda, Y., Hanaya, K., Shoji, M. & Sugai, T., 2017, In: Heterocycles. 95, 2, p. 862-871 10 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of a novel glycosphingolipid from the millipede, Parafontaria laminata armigera, and the assembly of its carbohydrate moiety into multivalent structures

Hada, N., Sonoda, Y. & Takeda, T., 2006 7月 24, In: Carbohydrate Research. 341, 10, p. 1341-1352 12 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Synthesis of a new glycosphingolipid, neurosporaside, from Neurospora crassa

Ohtsuka, I., Hada, N., Kanemaru, M., Fujii, T., Atsumi, T. & Kakiuchi, N., 2015 3月 2, In: Carbohydrate Research. 404, p. 9-16 8 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Synthesis of acacetin and resveratrol 3,5-di-O-β-glucopyranoside using lipase-catalyzed regioselective deacetylation of polyphenol glycoside peracetates as the key step

Hanamura, S., Hanaya, K., Shoji, M. & Sugai, T., 2016 6月 1, In: Journal of Molecular Catalysis B: Enzymatic. 128, p. 19-26 8 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Synthesis of a C₇₀ Fragment Buckybowl C₂₈H₁₄ from a C₆₀ fragment sumanene

Hishikawa, S., Okabe, Y., Tsuruoka, R., Higashibayashi, S., Ohtsu, H., Kawano, M., Yakiyama, Y. & Sakurai, H., 2017, In: Chemistry Letters. 46, 10, p. 1556-1559 4 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

Synthesis of 5-Hydroxy-3′,4′,7-trimethoxyflavone and Related Compounds and Elucidation of Their Reversal Effects on BCRP/ABCG2-Mediated Anticancer Drug Resistance

Tsunekawa, R., Katayama, K., Hanaya, K., Higashibayashi, S., Sugimoto, Y. & Sugai, T., 2019 1月 18, In: ChemBioChem. 20, 2, p. 210-220 11 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis of 3β-tert-Butyldimethylsiloxy-22-phenylthio-23,24-bisnorchola-5,9(11)-diene and Reductive Nucleophilic Attack on a Branched Aliphatic Aldehyde

Nagai, T., Hanaya, K., Higashibayashi, S., Shoji, M. & Sugai, T., 2018, In: Chemical and Pharmaceutical Bulletin. 66, 3, p. 334-338 5 p.

研究成果: Article › 査読

Open Access

Synthesis of 1H-2-Benzopyran-5,8-dione Skeleton through a Cascade Reaction between Benzoquinone and β-Ketoester

Nakahara, M., Ohtsu, H., Kawano, M., Hanaya, K., Sugai, T. & Higashibayashi, S., 2022 4月, In: Chemistry Letters. 51, 4, p. 356-359 4 p.

研究成果: Article › 査読

Synthesis of (Rc,Ss)-1,1,1-trifluoro-3-(p-molylsulfinyl)-2-propanol by an asymmetric reduction with a yeast, Yamadazyma farinosa, as a key-step

Sakai, A., Bakke, M., Ohta, H., Kosugi, H. & Sugai, T., 1999, In: Chemistry Letters. 11, p. 1255-1256 2 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Synthesis and release of acetylcholine by cultured bovine arterial endothelial cells

Kawashima, K., Watanabe, N., Oohata, H., Fujimoto, K., Suzuki, T., Ishizaki, Y., Morita, I. & Murota, S. I., 1990 11月 13, In: Neuroscience Letters. 119, 2, p. 156-158 3 p.

研究成果: Article › 査読

32 被引用数 (Scopus)

Synthesis and property of three-dimensional curved heterocyclic π-electron molecules with embedded nitrogen atoms

Higashibayashi, S., 2019, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 77, 12, p. 1209-1221 13 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Synthesis and properties of novel bifunctional nitrosamines with ω-chloroalkyl groups

Ishikawa, S., Saitoh, N. & Mochizuki, M., 2000, In: Chemical and Pharmaceutical Bulletin. 48, 10, p. 1500-1503 4 p.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Synthesis and Properties of Hydrazine-Embedded Biphenothiazines and Application of Hydrazine-Embedded Heterocyclic Compounds to Fluorescence Cell Imaging

Shindo, Y., Nomura, S., Saikawa, Y., Nakata, M., Tanaka, K., Hanaya, K., Sugai, T. & Higashibayashi, S., 2018 9月, In: Asian Journal of Organic Chemistry. 7, 9, p. 1797-1801 5 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Synthesis and properties of bifunctional chloroalkyl nitrosamines with an intercalating moiety

Ishikawa, S., Tajima, M. & Mochizuki, M., 2004 7月 15, In: Bioorganic and Medicinal Chemistry. 12, 14, p. 3791-3796 6 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Synthesis and evaluation of tofacitinib analogs designed to mitigate metabolic activation

Tateishi, Y., Shibazaki, C., Takahashi, K., Nakamura, S., Kazuki, Y., Mashino, T. & Ohe, T., 2022 4月, In: Drug Metabolism And Pharmacokinetics. 43, 100439.

研究成果: Article › 査読

1 被引用数 (Scopus)

Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine

Tateishi, Y., Ohe, T., Yasuda, D., Takahashi, K., Nakamura, S., Kazuki, Y. & Mashino, T., 2020 4月, In: Drug Metabolism And Pharmacokinetics. 35, 2, p. 238-243 6 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myeloma

Suto, Y., Sato, M., Fujimori, K., Kitabatake, S., Okayama, M., Ichikawa, D., Matsushita, M., Yamagiwa, N., Iwasaki, G., Kiuchi, F. & Hattori, Y., 2017, In: Bioorganic and Medicinal Chemistry Letters. 27, 19, p. 4558-4563 6 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Synthesis and biological evaluation of derivatives of 2-{2-fluoro-4-[(2- oxocyclopentyl)methyl]phenyl}propanoic acid: Nonsteroidal anti-inflammatory drugs with low gastric ulcerogenic activity

Yamakawa, N., Suemasu, S., Okamoto, Y., Tanaka, K. I., Ishihara, T., Asano, T., Miyata, K., Otsuka, M. & Mizushima, T., 2012 6月 14, In: Journal of Medicinal Chemistry. 55, 11, p. 5143-5150 8 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

Synthesis and biological evaluation of 12,13-cyclopropyl and 12,13-cyclobutyl epothilones

Nicolaou, K. C., Namoto, K., Li, J., Ritzén, A., Ulven, T., Shoji, M., Zaharevitz, D., Gussio, R., Sackett, D. L., Ward, R. D., Hensler, A., Fojo, T. & Giannakakou, P., 2001 1月 1, In: ChemBioChem. 2, 1, p. 69-75 7 p.

研究成果: Article › 査読

37 被引用数 (Scopus)

Synthesis and biological comparison of enantiomers of mepenzolate bromide, a muscarinic receptor antagonist with bronchodilatory and anti-inflammatory activities

Yamashita, Y., Tanaka, K. I., Asano, T., Yamakawa, N., Kobayashi, D., Ishihara, T., Hanaya, K., Shoji, M., Sugai, T., Wada, M., Mashimo, T., Fukunishi, Y. & Mizushima, T., 2014 7月 1, In: Bioorganic and Medicinal Chemistry. 22, 13, p. 3488-3497 10 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Synthesis and biological assessment of hemiacetal spiro derivatives towards development of efficient chemotherapeutic agent

Ogamino, T., Ohnishi, S., Ishikawa, Y., Sugai, T., Obata, R. & Nishiyama, S., 2006 3月, In: Science and Technology of Advanced Materials. 7, 2, p. 175-183 9 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Synthesis and antitumor activity of novel pyridinium fullerene derivatives

Yasuno, T., Ohe, T., Ikeda, H., Takahashi, K., Nakamura, S. & Mashino, T., 2019, In: International journal of nanomedicine. 14, p. 6325-6337 13 p.

研究成果: Article › 査読

Open Access

12 被引用数 (Scopus)

Synthesis and antigenicity against human sera of a biotin-labeled oligosaccharide portion of a glycosphingolipid from the parasite Echinococcus multilocularis

Hada, N., Kitamura, A., Yamano, K., Schweizer, F. & Kiuchi, F., 2016, In: Chemical and Pharmaceutical Bulletin. 64, 7, p. 865-873 9 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Synthesis, radical scavenging activity and structure-activity relationship of uric acid analogs

Yasuda, D., Takahashi, K., Kakinoki, T., Tanaka, Y., Ohe, T., Nakamura, S. & Mashino, T., 2013 3月, In: MedChemComm. 4, 3, p. 527-529 3 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Syntheses of optically active citronellol, citronellal, and citronellic acid by microbial oxidation and double coupling system in an interface bioreactor

Oda, S., Sugai, T. & Ohta, H., 2000 12月 1, In: Bulletin of the Chemical Society of Japan. 73, 12, p. 2819-2823 5 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Syntheses of new model compounds related to an antigenic epitope from Bupleurum falcatum L. and their distributions in various ganglioside- phospholipid monolayers

Hada, N., Jin, Y., Takeda, T., Ohtsuka, I. & Yokoyama, S., 2006, In: Chemical and Pharmaceutical Bulletin. 54, 9, p. 1281-1284 4 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Syntheses of indirubins by aldol condensation of isatins with indoxyl anion generated in situ by lipase-catalyzed deacetylation of indoxyl acetate

Sugai, T., Hanaya, K. & Higashibayashi, S., 2020, In: Heterocycles. 100, 1, p. 129-136 8 p.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Syntheses of Highly Oxygen-functionalized Derivatives of Dihydrodihydroxyphthalic Acid in Enantiomerically Enriched Forms

Ikeda, H., Hosomi, H., Ohba, S., Ohta, H. & Sugai, T., 1998, In: Bioscience, Biotechnology and Biochemistry. 62, 2, p. 396-400 5 p.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Syntheses of glycoclusters containing a phosphocholine residue related to a glycosphingolipid from the earthworm Pheretima hilgendorfi

Hada, N., Shida, Y., Negishi, N., Schweizer, F. & Takeda, T., 2009 10月, In: Chemical and Pharmaceutical Bulletin. 57, 10, p. 1081-1088 8 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Synergistic Stimulation of Prostaglandin E2 Release by Epidermal Growth Factor and a Tumor Promoter Anthralin from Primary Cultures of Mouse Epidermal Cells

Aizu, E., Yamamoto, S., Nishikawa, K. & Kato, R., 1991 1月, In: The Japanese Journal of Pharmacology. 57, 3, p. 361-366 6 p.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Synergistic effect of indomethacin and adriamycin and cisplatin on tumor growth

Hattori, K., Matsushita, R., Kimura, K., Abe, Y. & Nakashima, E., 2001, In: Biological and Pharmaceutical Bulletin. 24, 10, p. 1214-1217 4 p.

研究成果: Article › 査読

23 被引用数 (Scopus)

Synergistic effect of baicalein, wogonin and oroxylin A mixture: multistep inhibition of the NF-κB signalling pathway contributes to an anti-inflammatory effect of Scutellaria root flavonoids

Shimizu, T., Shibuya, N., Narukawa, Y., Oshima, N., Hada, N. & Kiuchi, F., 2018 1月 1, In: Journal of Natural Medicines. 72, 1, p. 181-191 11 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Synergistic antitumor interaction of human monocyte chemotactant protein-1 gene transfer and modulator for tumor-infiltrating macrophages

Nakashima, E., Kubota, Y., Matsushita, R., Ozaki, E., Ichimura, F., Kawahara, S., Nakanishi, I., Kuno, K. & Matsushima, K., 1998 6月 26, In: Pharmaceutical research. 15, 5, p. 685-689 5 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Synergistic action of statins and nitrogen-containing bisphosphonates in the development of rhabdomyolysis in L6 rat skeletal myoblasts

Matzno, S., Nishiguchi, T., Akiyoshi, T., Anami, S., Nakabayashi, T. & Matsuyama, K., 2009 6月, In: Journal of Pharmacy and Pharmacology. 61, 6, p. 781-788 8 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon

Nakamura, A., Kurihara, S., Takahashi, D., Ohashi, W., Nakamura, Y., Kimura, S., Onuki, M., Kume, A., Sasazawa, Y., Furusawa, Y., Obata, Y., Fukuda, S., Saiki, S., Matsumoto, M. & Hase, K., 2021 12月 1, In: Nature communications. 12, 1, 2105.

研究成果: Article › 査読

Open Access

51 被引用数 (Scopus)

Sustained subcutaneous infusion of nicotine enhances cholinergic vasodilation in the cerebral cortex induced by stimulation of the nucleus basalis of Meynert in rats

Uchida, S., Hotta, H., Misawa, H. & Kawashima, K., 2011 3月 11, In: European journal of pharmacology. 654, 3, p. 235-240 6 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Susceptibility of experimental autoimmune hepatitis in transgenic mice overexpressing the c-H-ras gene

Tsunematsu, S., Saito, H., Tada, S., Ebinuma, H., Tsuchiya, M., Kumagai, N., Morizane, T., Nomura, T. & Ishii, H., 1997 1月 1, In: Journal of Gastroenterology and Hepatology (Australia). 12, 4, p. 319-324 6 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Survey on the attitudes of pharmacy students in Japan toward doping and supplement intake

Saito, Y., Kasashi, K., Yoshiyama, Y., Fukushima, N., Kawagishi, T., Yamada, T. & Iseki, K., 2013 2月, In: Biological and Pharmaceutical Bulletin. 36, 2, p. 305-310 6 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Survey on off-label use of antineoplastic agents in pediatric patients using a large-scale medical database in japan

Kuroda, M., Nakamura, A., Tanemura, N., Nakakuni, M., Sato, J. & Urushihara, H., 2020, In: Japanese Journal of Clinical Pharmacology and Therapeutics. 51, 6, p. 307-316 10 p.

研究成果: Article › 査読

Survey on concurrent prescriptions for quinolones with non-steroidal anti-inflammatory drugs in 2 urban hospitals

Kizu, J., Kaneda, M., Aoki, K., Miyazaki, Y., Ohta, T. & Hori, S., 2003 9月 1, In: Japanese Journal of Chemotherapy. 51, 9, p. 561-568 8 p.

研究成果: Article › 査読

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