年別の研究成果
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Article
Acetylcholine synthesis and release in NIH3T3 cells coexpressing the high-affinity choline transporter and choline acetyltransferase
Fujii, T., Masai, M., Misawa, H., Okuda, T., Takada-Takatori, Y., Moriwaki, Y., Haga, T. & Kawashima, K., 2009 10月 1, In: Journal of neuroscience research. 87, 13, p. 3024-3032 9 p.研究成果: Article › 査読
16 被引用数 (Scopus) -
Acetylcholine synthesis is modulated by acetylcholine content of cytosolic fraction but not by that of releasable fraction
Suzuki, T., Kashima, Y., Fujimoto, K. & Kawashima, K., 1992 9月 14, In: Neuroscience Letters. 144, 1-2, p. 127-129 3 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
A Chemical Model of Catechol-O-methyltransferase: Methylation of 3,4-Dihydroxybenzaldehyde in Aqueous Solution
Sugata, S., Ishihara, S., (nee Tamano), Y. W., Nagata, Y. & Matsushima, Y., 1989, In: Chemical and Pharmaceutical Bulletin. 37, 5, p. 1143-1146 4 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
A chemical model of catechol-O-methyltransferase. II
Sugata, S. & Matsushima, Y., 1987 1月 1, In: Journal of Pharmacobio-Dynamics. 10, 1, p. s-20研究成果: Article › 査読
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A Chemical Model of Catechol-O-methyltransferase. Methylation of 3,4-Dihydroxybenzaldehyde in Methanol Solution
Sugata, S., 1993 1月 1, In: Chemical and Pharmaceutical Bulletin. 41, 6, p. 1007-1011 5 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
A chemical model of catechol-o-methyltransferase. V
Sugata, S. & Matsushima, Y., 1991 12月 1, In: Journal of Pharmacobio-Dynamics. 14, 11, p. s-117研究成果: Article › 査読
1 被引用数 (Scopus) -
A chemo-enzymatic elaboration of a quarternary chiral center: An alternative approach to the side chain of furaquinocin D
Akeboshi, T., Ohtsuka, Y., Sugai, T. & Ohta, H., 1998 6月 25, In: Tetrahedron. 54, 26, p. 7387-7394 8 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
A chemo-enzymatic expeditious route to racemic dihexanoyl (2R*,3R*,4R*)-dehydroxymethylepoxyquinomycin (DHMEQ), the precursor for lipase-catalyzed synthesis of the potent nuclear factor-κB inhibitor, (2 S,3S,4 S )-DHMEQ
Kobayashi, R., Hanaya, K., Shoji, M., Umezawa, K. & Sugai, T., 2012 9月, In: Chemical and Pharmaceutical Bulletin. 60, 9, p. 1220-1223 4 p.研究成果: Article › 査読
8 被引用数 (Scopus) -
A Chemo-Enzymatic Synthesis of D-Allosamine Derivatives from Tri-O-acetyl- D-glucal
Sugai, T., Okazaki, H., Kuboki, A. & Ohta, H., 1997 10月, In: Bulletin of the Chemical Society of Japan. 70, 10, p. 2535-2540 6 p.研究成果: Article › 査読
5 被引用数 (Scopus) -
Acidic catecholamine metabolites and 5-hydroxyindoleacetic acid in urine: The influence of diet
Mashige, F., Matsushima, Y., Kanazawa, H., Sakuma, I., Takai, N., Bessho, F. & Ohkubo, A., 1996, In: Annals of Clinical Biochemistry. 33, 1, p. 43-49 7 p.研究成果: Article › 査読
33 被引用数 (Scopus) -
Acidic phospholipids inhibit the DNA-binding activity of DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli
Makise, M., Mima, S., Katsu, T., Tsuchiya, T. & Mizushima, T., 2002, In: Molecular Microbiology. 46, 1, p. 245-256 12 p.研究成果: Article › 査読
33 被引用数 (Scopus) -
Acid suppression by proton pump inhibitors enhances aquaporin-4 and KCNQ1 expression in gastric fundic parietal cells in mouse
Matsuzaki, J., Suzuki, H., Minegishi, Y., Sugai, E., Tsugawa, H., Yasui, M. & Hibi, T., 2010 12月, In: Digestive Diseases and Sciences. 55, 12, p. 3339-3348 10 p.研究成果: Article › 査読
27 被引用数 (Scopus) -
A comment on the evaluation of equilibrium constants for α-tocopherol interactions with fatty acids by absorbance in the ultraviolet region
Sugata, S., Urano, S., Matsushima, Y. & Matsuo, M., 1988 10月 14, In: Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism. 962, 3, p. 385-386 2 p.研究成果: Article › 査読
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A Comparative Study of the Market Configuration of the Japanese Pharmaceutical Market Using the Gini Coefficient and Herfindahl–Hirschman Index
Shibata, S., Fukumoto, D., Suzuki, T. & Ozaki, K., 2020 9月 1, In: Therapeutic Innovation and Regulatory Science. 54, 5, p. 1047-1055 9 p.研究成果: Article › 査読
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A Comparison of Uridine Diphosphate-Glucuronosyl-Transferase and Other Drug Metabolizing Enzyme Activities Between Two Mutant Strains of Wistar Rats with A Genetic Deficiency in Bilirubin or Androsterone Glucuronidation
Nagai, F., Takahashi, M., Homma, H., Matsui, M. & Tanase, H., 1987, In: Journal of Pharmacobio-Dynamics. 10, 8, p. 421-426 6 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
A Concise Total Synthesis of Dehydroantofine and Its Antimalarial Activity against Chloroquine-Resistant Plasmodium falciparum
Yamasaki, N., Iwasaki, I., Sakumi, K., Hokari, R., Ishiyama, A., Iwatsuki, M., Nakahara, M., Higashibayashi, S., Sugai, T., Imagawa, H., Kubo, M., Fukuyama, Y., Ōmura, S. & Yamamoto, H., 2021 3月 22, In: Chemistry - A European Journal. 27, 17, p. 5555-5563 9 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis
Tokuda, E., Nomura, T., Ohara, S., Watanabe, S., Yamanaka, K., Morisaki, Y., Misawa, H. & Furukawa, Y., 2018 6月, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1864, 6, p. 2119-2130 12 p.研究成果: Article › 査読
Open Access18 被引用数 (Scopus) -
Acquisition of double mutation in gyrA caused high resistance to sitafloxacin in Helicobacter pylori after unsuccessful eradication with sitafloxacin-containing regimens
Mori, H., Suzuki, H., Matsuzaki, J., Masaoka, T. & Kanai, T., 2018 4月 1, In: United European Gastroenterology Journal. 6, 3, p. 391-397 7 p.研究成果: Article › 査読
Open Access20 被引用数 (Scopus) -
Action of L-aminoacylase and L-amino acid oxidase on 2-amino-3- methylpent-4-enoic acid [Δ(4)-dehydroisoleucine and alloisoleucine] stereoisomers: An alternative route to a stereochemically pure compound and the application to the synthesis of (R)-2-methylbutan-1-ol
Bakke, M., Ohta, H., Kazmaier, U. & Sugai, T., 1999, In: Synthesis. 9, p. 1671-1677 7 p.研究成果: Article › 査読
7 被引用数 (Scopus) -
Action of nitrile hydratase from rhodococcus rhodochrous IFO 15564 on Derivatives of 2,5-Anhydro-d-allononitrile
Yokoyama, M., Nakatsuka, Y., Sugai, T. & Ohta, H., 1996 1月, In: Bioscience, Biotechnology and Biochemistry. 60, 9, p. 1540-1542 3 p.研究成果: Article › 査読
Open Access7 被引用数 (Scopus) -
Activating mutations in EGFR and PI3K promote ATF4 induction for NSCLC cell survival during amino acid deprivation
Takahashi, M., Okamoto, Y., Kato, Y., Shirahama, H., Tsukahara, S., Sugimoto, Y. & Tomida, A., 2023 4月, In: Heliyon. 9, 4, e14799.研究成果: Article › 査読
Open Access -
Activation Mechanism of N-Nitrosodialkylamines as Environmental Mutagens and Its Application to Antitumor Research
Inami, K., Ishikawa, S., Mochizuki, M. & Ishikawa, S., 2009, In: Genes and Environment. 31, 4, p. 97-104 8 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
Activation of 5’-Deoxy-5-fluorouridine by Thymidine Phosphorylase in Human Tumors
Kono, A., Hara, Y., Sugata, S., Karube, Y., Matsushima, Y. & Ishitsuka, H., 1983 1月 1, In: Chemical and Pharmaceutical Bulletin. 31, 1, p. 175-178 4 p.研究成果: Article › 査読
Open Access41 被引用数 (Scopus) -
Activation of carboxyl groups by diphenyl 2-oxo-3-oxazolinylphosphonate. Facile preparation of versatile reagents, 3-acyl-2-oxazolones
Kunieda, T., Higuchi, T., Abe, Y. & Hirobe, M., 1983, In: Tetrahedron. 39, 20, p. 3253-3260 8 p.研究成果: Article › 査読
10 被引用数 (Scopus) -
Active Oxidants Mediate IFN-α-Induced Microvascular Alterations in Rat Mesentery
Higuchi, H., Kurose, I., Fukumura, D., Yan, H. J., Saito, H., Miura, S., Hokari, R., Watanabe, N., Zeki, S., Yoshida, M., Kitajima, M., Granger, D. N. & Ishii, H., 1997 5月 15, In: Journal of Immunology. 158, 10, p. 4893-4900 8 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking
Saeed, M., Kadioglu, O., Khalid, H., Sugimoto, Y. & Efferth, T., 2015, In: Journal of Nutritional Biochemistry. 26, 1, p. 44-56 13 p.研究成果: Article › 査読
70 被引用数 (Scopus) -
Actual status of adverse reactions to antimicrobials covered/not covered by a public relief system
Sato, S., Matsumoto, K., Kuroda, Y. & Kizu, J., 2016 7月, In: Japanese Journal of Chemotherapy. 64, 4, p. 656-662 7 p.研究成果: Article › 査読
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Acute hepatic failure in a 49-year-old man succeeding to a surgery for malignant thymoma.
Ishii, H., Yokoyama, A., Takebe, N., Hibi, T., Saito, H., Oda, M., Tsuchiya, M., Handa, M., Akasaka, Y. & Hosoda, Y., 1992 6月, In: The Keio Journal of Medicine. 41, 2, p. 99-105 7 p.研究成果: Article › 査読
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Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-β treatment for chronic hepatitis C
Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M. & Ishii, H., 2004 7月 1, In: Hepato-gastroenterology. 51, 58, p. 1109-1114 6 p.研究成果: Article › 査読
3 被引用数 (Scopus) -
A developed determination of midazolam and 1′-hydroxymidazolam in plasma by liquid chromatography-mass spectrometry: Application of human pharmacokinetic study for measurement of CYP3A activity
Shimizu, M., Uno, T., Tamura, H. O., Kanazawa, H., Murakami, I., Sugawara, K. & Tateishi, T., 2007 3月 1, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 847, 2, p. 275-281 7 p.研究成果: Article › 査読
30 被引用数 (Scopus) -
Adiponectin is regulated differently by chronic exercise than by weight-matched food restriction in hyperphagic and obese OLETF rats
Kimura, M., Shinozaki, T., Tateishi, N., Yoda, E., Yamauchi, H., Suzuki, M., Hosoyamada, M. & Shibasaki, T., 2006 10月 26, In: Life Sciences. 79, 22, p. 2105-2111 7 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
ADIPOR1 deficiency-induced suppression of retinal ELOVL2 and docosahexaenoic acid levels during photoreceptor degeneration and visual loss
Osada, H., Toda, E., Homma, K., Guzman, N. A., Nagai, N., Ogawa, M., Negishi, K., Arita, M., Tsubota, K. & Ozawa, Y., 2021 5月, In: Cell Death and Disease. 12, 5, 458.研究成果: Article › 査読
Open Access13 被引用数 (Scopus) -
Administration of antioxidant compounds affects the lens chaperone activity and prevents the onset of cataracts
Nakazawa, Y., Nagai, N., Ishimori, N., Oguchi, J. & Tamura, H., 2017 11月, In: Biomedicine and Pharmacotherapy. 95, p. 137-143 7 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
Adolescent Mental Health, Behavior Problems, and Academic Achievement
McLeod, J. D., Uemura, R. & Rohrman, S., 2012 12月, In: Journal of Health and Social Behavior. 53, 4, p. 482-497 16 p.研究成果: Article › 査読
172 被引用数 (Scopus) -
A double-helical S,C-bridged tetraphenyl-para-phenylenediamine and its persistent radical cation
Harada, K., Hasegawa, C., Matsumoto, T., Sugishita, H., Kitamura, C., Higashibayashi, S., Hasegawa, M., Suzuki, S. & Kato, S. I., 2022 12月 31, In: Chemical Communications. 59, 10, p. 1301-1304 4 p.研究成果: Article › 査読
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Adsorption-Desorption Control of Fibronectin in Real Time at the Liquid/Polymer Interface on a Quartz Crystal Microbalance by Thermoresponsivity
Li, J., Kaku, T., Tokura, Y., Matsukawa, K., Homma, K., Nishimoto, T., Hiruta, Y., Akimoto, A. M., Nagase, K., Kanazawa, H. & Shiratori, S., 2019 4月 8, In: Biomacromolecules. 20, 4, p. 1748-1755 8 p.研究成果: Article › 査読
13 被引用数 (Scopus) -
Advanced oxidation protein products contribute to chronic kidney disease-induced muscle atrophy by inducing oxidative stress via CD36/NADPH oxidase pathway
Kato, H., Watanabe, H., Imafuku, T., Arimura, N., Fujita, I., Noguchi, I., Tanaka, S., Nakano, T., Tokumaru, K., Enoki, Y., Maeda, H., Hino, S., Tanaka, M., Matsushita, K., Fukagawa, M. & Maruyama, T., 2021 12月, In: Journal of Cachexia, Sarcopenia and Muscle. 12, 6, p. 1832-1847 16 p.研究成果: Article › 査読
Open Access13 被引用数 (Scopus) -
Adverse effects of anticholinergic activity on cognitive functions in Alzheimer's disease
Konishi, K., Hori, K., Uchida, H., Watanabe, K., Tominaga, I., Kimura, M., Hosoyamada, M., Shibasaki, T., Kataoka, A. & Hachisu, M., 2010 3月, In: Psychogeriatrics. 10, 1, p. 34-38 5 p.研究成果: Article › 査読
28 被引用数 (Scopus) -
A facile access to aryl α-sialosides: The combination of a volatile amine base and acetonitrile in glycosidation of sialosyl chlorides
Kuboki, A., Sekiguchi, T., Sugai, T. & Ohta, H., 1998 5月, In: Synlett. 5, p. 479-482 4 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
Age-associated theophylline metabolic activity corresponds to the ratio of 1,3-dimethyluric acid to theophylline in mice
Kuroda, Y., Taguchi, K., Enoki, Y., Matsumoto, K., Hori, S. & Kizu, J., 2019, In: Biological and Pharmaceutical Bulletin. 42, 8, p. 1423-1427 5 p.研究成果: Article › 査読
Open Access -
Age-related changes in pharmacokinetic parameters of phenytoin after liver resection in rats
Nakashima, E., Matsushita, R., Iida, Y., Ohshima, T. & Ichimura, F., 1995, In: Pharmaceutical research. 12, 10, p. 1530-1534 5 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Age-Related Trends in Home Blood Pressure, Home Pulse Rate, and Day-to-Day Blood Pressure and Pulse Rate Variability Based on Longitudinal Cohort Data: The Ohasama Study
Satoh, M., Metoki, H., Asayama, K., Murakami, T., Inoue, R., Tsubota-Utsugi, M., Matsuda, A., Hirose, T., Hara, A., Obara, T., Kikuya, M., Nomura, K., Hozawa, A., Imai, Y. & Ohkubo, T., 2019 8月 6, In: Journal of the American Heart Association. 8, 15, e012121.研究成果: Article › 査読
Open Access11 被引用数 (Scopus) -
A Glucan Having Reticuloendothelial System-Potentiating and Anti-complementary Activities from the Tuber of Pinellia ternata
Tomoda, M., Gonda, R., Ōhara, N., Shimizu, N., Shishido, C. & Fujiki, Y., 1994, In: Biological and Pharmaceutical Bulletin. 17, 6, p. 859-861 3 p.研究成果: Article › 査読
Open Access8 被引用数 (Scopus) -
A Glucan with Immunological Activities from the Tuber of Alisma orientale
Shimizu, N., Ohtsu, S., Tomoda, M., Gonda, R. & Ōhara, N., 1994 1月 1, In: Biological and Pharmaceutical Bulletin. 17, 12, p. 1666-1668 3 p.研究成果: Article › 査読
Open Access12 被引用数 (Scopus) -
Agonist-induced sequestration, recycling, and resensitization of platelet-activating factor receptor: Role of cytoplasmic tail phosphorylation in each process
Ishii, I., Saito, E., Izumi, T., Ui, M. & Shimizu, T., 1998 4月 17, In: Journal of Biological Chemistry. 273, 16, p. 9878-9885 8 p.研究成果: Article › 査読
46 被引用数 (Scopus) -
A handy system for gel electrophoresis
Nishizawa, H. & Abe, Y., 1986, In: BUNSEKI KAGAKU. 35, 3研究成果: Article › 査読
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A highly active 4-siloxyproline catalyst for asymmetric synthesis
Hayashi, Y., Yamaguchi, J., Hibino, K., Sumiya, T., Urushima, T., Shoji, M., Hashizume, D. & Koshino, H., 2004 10月 1, In: Advanced Synthesis and Catalysis. 346, 12, p. 1435-1439 5 p.研究成果: Article › 査読
131 被引用数 (Scopus) -
A historical review on International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) and internationalization of Japan's new drugs development and regulation
Kurokawa, T., 2014 1月 1, In: Yakushigaku zasshi. The Journal of Japanese history of pharmacy. 49, 2, p. 165-170 6 p.研究成果: Article › 査読
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Airway M Cells arise in the lower airway due to RANKL signaling and reside in the bronchiolar epithelium associated with iBALT in murine models of respiratory disease
Kimura, S., Mutoh, M., Hisamoto, M., Saito, H., Takahashi, S., Asakura, T., Ishii, M., Nakamura, Y., Iida, J., Hase, K. & Iwanaga, T., 2019, In: Frontiers in Immunology. 10, JUN, 1323.研究成果: Article › 査読
Open Access15 被引用数 (Scopus) -
Akt activation through the phosphorylation of erythropoietin receptor at tyrosine 479 is required for myeloproliferative disorder-associated JAK2 V617F mutant-induced cellular transformation
Kamishimoto, J., Tago, K., Kasahara, T. & Funakoshi-Tago, M., 2011 5月, In: Cellular Signalling. 23, 5, p. 849-856 8 p.研究成果: Article › 査読
26 被引用数 (Scopus)