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Article

Enantiomeric determination of L- and D-lactic acid in human cerebrospinal fluid by chiral ligand exchange high-performance liquid chromatography

Okubo, S., Mashige, F., Omori, M., Hashimoto, Y., Nakahara, K., Kanazawa, H. & Matsushima, Y., 2000 11月 29, In: Biomedical Chromatography. 14, 7, p. 474-477 4 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Enantioselective binding of (±)-2-bromoisovalerylurea to serum albumins

Abe, Y., Kotaki, F., Fukui, S., Kawaguchi, M., Furudate, F., Shoji, T., Sugata, S., Nishizawa, H., Iwata, K. & Suzuki, H., 1999 4月, In: analytical sciences. 15, 4, p. 397-398 2 p.

研究成果: Article › 査読

Open Access

Enantioselective binding sites on bovine serum albumin to dansyl amino acids

Abe, Y., Fukui, S., Koshiji, Y., Kobayashi, M., Shoji, T., Sugata, S., Nishizawa, H., Suzuki, H. & Iwata, K., 1999 8月 17, In: Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology. 1433, 1-2, p. 188-197 10 p.

研究成果: Article › 査読

20 被引用数 (Scopus)

Enantioselective distribution behavior of (±)-pindolol in a liquid- liquid two-phase system containing optically active diol and boric acid

Abe, Y., Qing, W., Shoji, T., Fukui, S., Suzuki, M., Kamiyama, T., Kobayashi, M. & Nishizawa, H., 1996 6月, In: Chemical and Pharmaceutical Bulletin. 44, 6, p. 1250-1251 2 p.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Enantioselective synthesis of heliannuol E; structural consideration of natural molecule

Doi, F., Ogamino, T., Sugai, T. & Nishiyama, S., 2003 6月 23, In: Tetrahedron Letters. 44, 26, p. 4877-4880 4 p.

研究成果: Article › 査読

45 被引用数 (Scopus)

Enantioselective synthesis of the medium ring ethers, tetrahydrooxepin, oxocane and hexahydrooxonin, of ciguatoxin. Extensive ring-expansion and chemoenzymatic desymmetrization strategy

Oishi, T., Maruyama, M., Shoji, M., Maeda, K., Kumahara, N., Tanaka, S. I. & Hirama, M., 1999 6月 11, In: Tetrahedron. 55, 24, p. 7471-7498 28 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

Enantioseparation by dual-flow countercurrent extraction: Its application to the enantioseparation of (±)-propranolol

Abe, Y., Shoji, T., Fukui, S., Sasamoto, M. & Nishizawa, H., 1996 8月, In: Chemical and Pharmaceutical Bulletin. 44, 8, p. 1521-1524 4 p.

研究成果: Article › 査読

Open Access

26 被引用数 (Scopus)

Endogenous glutamatergic synaptic activity elicits acetylcholine release from rat cultured septal cells

Suzuki, T., Matsugi, T., Takagi, R. & Kawashima, K., 2003 11月 1, In: Neuroscience Research. 47, 3, p. 341-347 7 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Endogenous hydrogen sulfide protects pancreatic beta-cells from a high-fat diet-induced glucotoxicity and prevents the development of type 2 diabetes

Okamoto, M., Yamaoka, M., Takei, M., Ando, T., Taniguchi, S., Ishii, I., Tohya, K., Ishizaki, T., Niki, I. & Kimura, T., 2013 12月 13, In: Biochemical and Biophysical Research Communications. 442, 3-4, p. 227-233 7 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Endogenous neurotoxin-like protein Ly6H inhibits alpha7 nicotinic acetylcholine receptor currents at the plasma membrane

Moriwaki, Y., Kubo, N., Watanabe, M., Asano, S., Shinoda, T., Sugino, T., Ichikawa, D., Tsuji, S., Kato, F. & Misawa, H., 2020 12月 1, In: Scientific reports. 10, 1, 11996.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis

Tsutsumi, S., Gotoh, T., Tomisato, W., Mima, S., Hoshino, T., Hwang, H. J., Takenaka, H., Tsuchiya, T., Mori, M. & Mizushima, T., 2004 9月, In: Cell Death and Differentiation. 11, 9, p. 1009-1016 8 p.

研究成果: Article › 査読

202 被引用数 (Scopus)

Energy-dependent endocytosis is responsible for drug transcorneal penetration following the instillation of ophthalmic formulations containing indomethacin nanoparticles

Nagai, N., Ogata, F., Otake, H., Nakazawa, Y. & Kawasaki, N., 2019, In: International journal of nanomedicine. 14, p. 1213-1227 15 p.

研究成果: Article › 査読

Open Access

34 被引用数 (Scopus)

Energy resolution of liquid scintillator for α-particles and internal conversion electrons at lower temperatures

Homma, Y. & Murase, Y., 1987 12月, In: Journal of Radioanalytical and Nuclear Chemistry Letters. 119, 5, p. 355-365 11 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Enhanced bacterial efflux system is the first step to the development of metronidazole resistance in Helicobacter pylori

Tsugawa, H., Suzuki, H., Muraoka, H., Ikeda, F., Hirata, K., Matsuzaki, J., Saito, Y. & Hibi, T., 2011 1月 14, In: Biochemical and Biophysical Research Communications. 404, 2, p. 656-660 5 p.

研究成果: Article › 査読

34 被引用数 (Scopus)

Enhanced cellular uptake and gene silencing activity of siRNA using temperature-responsive polymer-modified liposome

Wang, J., Ayano, E., Maitani, Y. & Kanazawa, H., 2017 5月 15, In: International Journal of Pharmaceutics. 523, 1, p. 217-228 12 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Enhanced dissolution and oral bioavailability of praziquantel by emulsification with human serum albumin followed by spray drying

Yamasaki, K., Taguchi, K., Nishi, K., Otagiri, M. & Seo, H., 2019 11月 1, In: European Journal of Pharmaceutical Sciences. 139, 105064.

研究成果: Article › 査読

5 被引用数 (Scopus)

Enhanced mechanical properties and cell separation with thermal control of PIPAAm-brushed polymer-blend microfibers

Nagase, K., Shukuwa, R., Takahashi, H., Takeda, N. & Okano, T., 2020 7月 28, In: Journal of Materials Chemistry B. 8, 28, p. 6017-6026 10 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Enhanced pressor responsiveness to central cholinergic activation by physostigmine and impaired baroreflex function in spontaneously hypertensive rats

Kawashima, K., Miwa, Y. & Fujimoto, K., 1988 1月 1, In: Therapeutic Research. 9, 2, p. 144-153 10 p.

研究成果: Article › 査読

Enhanced serum antigen-specific IgG₁ and proinflammatory cytokine production in nicotinic acetylcholine receptor α7 subunit gene knockout mice

Fujii, Y. X., Fujigaya, H., Moriwaki, Y., Misawa, H., Kasahara, T., Grando, S. A. & Kawashima, K., 2007 9月, In: Journal of Neuroimmunology. 189, 1-2, p. 69-74 6 p.

研究成果: Article › 査読

69 被引用数 (Scopus)

Enhanced theophylline metabolism in patients with bronchial asthma at age 4 and under

Kizu, J., Arakawa, M., Arakawa, Y., Komoda, F., Takamizawa, M., Iwata, T., Hayakawa, T. & Imai, K., 1999, In: Biomedical Chromatography. 13, 7, p. 462-464 3 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Enhancement of androgen action in the kidneys of transgenic mice harboring the mutant human UMOD gene

Takiue, Y., Hosoyamada, M., Kimura, M. & Saito, H., 2011, In: Journal of Pharmacological Sciences. 115, 3, p. 383-389 7 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Enhancement of the serotonin-mediated acetylcholine release by repeated desmethylimipramine treatment in the hippocampus of freely moving rats

Fujii, T., Ohba, S., Nakai, K., Fujimoto, K., Suzuki, T. & Kawashima, K., 1999, In: Japanese Journal of Pharmacology. 80, 4, p. 303-309 7 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Enhancement of zidovudine transfer to molt-4 cells, a human t-cell model, by dehydroepiandrosterone sulfate

Nishimura, T., Tanaka, J., Tomi, M., Seki, Y., Kose, N., Sai, Y. & Nakashima, E., 2011 9月, In: Journal of Pharmaceutical Sciences. 100, 9, p. 3959-3967 9 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

enhancement of zidovudine uptake by dehydroepiandrosterone sulfate in rat syncytiotrophoblast cell line TR-TBT 18d-1

Nishimura, T., Seki, Y., Sato, K., Chishu, T., Kose, N., Terasaki, T., Kang, Y. S., Sai, Y. & Nakashima, E., 2008 10月, In: Drug Metabolism and Disposition. 36, 10, p. 2080-2085 6 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C

Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M. & Ishii, H., 1996 3月, In: Keio Journal of Medicine. 45, 1, p. 48-53 6 p.

研究成果: Article › 査読

Open Access

9 被引用数 (Scopus)

Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying

Fukuhara, S., Masaoka, T., Nishimura, S., Nakamura, M., Matsuzaki, J., Tsugawa, H., Miyoshi, S., Mori, H., Kawase, S., Shibata, S., Okano, H., Kanai, T. & Suzuki, H., 2017 12月 1, In: Digestive Diseases and Sciences. 62, 12, p. 3359-3369 11 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Environmental behavior on the lens opacification (Japanese)

Iwata, S., Ikemoto, F. & Takehana, M., 1976 12月 1, In: Journal of Japanese Ophthalmological Society. 80, 9, p. 741-748 8 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Enzymatic conversion of tegafur to 5-FU in human tumor tissue

Hara, Y., Sugata, S., Kono, A. & Tanaka, M., 1983, In: Japanese Journal of Cancer and Chemotherapy. 10, 6, p. 1511-1517 7 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Enzymatic kinetic resolution of cyanohydrin acetates and its application to the synthesis of (S)-(-)-frontalin

Ohta, H., Kimura, Y., Sugano, Y. & Sugai, T., 1989, In: Tetrahedron. 45, 17, p. 5469-5476 8 p.

研究成果: Article › 査読

60 被引用数 (Scopus)

Enzymatic Preparation of Enantiomerically Enriched Tertiary a-Benzyloxy Acid Esters. Application to the Synthesis of (S)-(-)-Frontalin

Sugai, T., Kakeya, H. & Ohta, H., 1990 1月 1, In: Journal of Organic Chemistry. 55, 15, p. 4643-4647 5 p.

研究成果: Article › 査読

64 被引用数 (Scopus)

Enzymatic preparation of ethyl (5)- 3-hydroxybutanoate with a high enantiomeric excess

Sugai, T. & Ohta, H., 1989 7月, In: Agricultural and biological chemistry. 53, 7, p. 2009-2010 2 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Enzymatic Preparation of Ethyl (S)-3-Hydroxybutanoate with a High Enantiomeric Excess

Sugai, T. & Ohta, H., 1989, In: Agricultural and biological chemistry. 53, 7, p. 2009-2010 2 p.

研究成果: Article › 査読

Enzyme- and microorganism-mediated syntheses of substances related to glycoconjugates

Kuboki, A., Bakke, M., Sekiguchi, T., Ohta, H. & Sugai, T., 1998 6月, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 56, 6, p. 489-499 11 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Enzyme-catalyzed enantiomeric resolution of N-Boc-proline as the key-step in an expeditious route towards RAMP

Kurokawa, M., Shindo, T., Suzuki, M., Nakajima, N., Ishihara, K. & Sugai, T., 2003 5月 16, In: Tetrahedron Asymmetry. 14, 10, p. 1323-1333 11 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

Enzyme-catalyzed resolution of 3,8-dioxatricyclo[3.2.1.0^2,4]octane-6-carboxylic esters and the application to the synthesis of 3-epishikimic acid

Hamada, M., Inami, Y., Nagai, Y., Higashi, T., Shoji, M., Ogawa, S., Umezawa, K. & Sugai, T., 2009 9月 23, In: Tetrahedron Asymmetry. 20, 18, p. 2105-2111 7 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

Enzyme-mediated optical resolution of 2-methyl-3,4-pentadien-1-ol, a chiral building block possessing terminal allenyl group

Konegawa, T., Ohtsuka, Y., Ikeda, H., Sugai, T. & Ohta, H., 1997, In: Synlett. 1997, 11, p. 1297-1299 3 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Eosinophils promote corneal wound healing via the 12/15-lipoxygenase pathway

Ogawa, M., Ishihara, T., Isobe, Y., Kato, T., Kuba, K., Imai, Y., Uchino, Y., Tsubota, K. & Arita, M., 2020 9月 1, In: FASEB Journal. 34, 9, p. 12492-12501 10 p.

研究成果: Article › 査読

Open Access

7 被引用数 (Scopus)

Epigallocatechin gallate (EGCG) inhibits the sulfation of 1-naphthol in a human colon carcinoma cell line, Caco-2

Isozaki, T. & Tamura, H. O., 2001, In: Biological and Pharmaceutical Bulletin. 24, 9, p. 1076-1078 3 p.

研究成果: Article › 査読

30 被引用数 (Scopus)

Epigenetic alterations and microRNA misexpression in cancer and autoimmune diseases: a critical review

Saito, Y., Saito, H., Liang, G. & Friedman, J. M., 2014 10月 1, In: Clinical reviews in allergy & immunology. 47, 2, p. 128-135 8 p.

研究成果: Article › 査読

55 被引用数 (Scopus)

Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging

Uchida, R., Saito, Y., Nogami, K., Kajiyama, Y., Suzuki, Y., Kawase, Y., Nakaoka, T., Muramatsu, T., Kimura, M. & Saito, H., 2019 12月 1, In: npj Aging and Mechanisms of Disease. 5, 1, 1.

研究成果: Article › 査読

Open Access

11 被引用数 (Scopus)

Epimerization of Aldoses Catalyzed by Dioxobis(2,4-pentanedionato-O,O′)-molybdenum (VI). An Improved Procedure for C-2 Epimer Preparation

Abe, Y., Kunieda, T. & Takizawa, T., 1980, In: Chemical and Pharmaceutical Bulletin. 28, 4, p. 1324-1326 3 p.

研究成果: Article › 査読

28 被引用数 (Scopus)

Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues

Obata, Y., Kimura, S., Nakato, G., Iizuka, K., Miyagawa, Y., Nakamura, Y., Furusawa, Y., Sugiyama, M., Suzuki, K., Ebisawa, M., Fujimura, Y., Yoshida, H., Iwanaga, T., Hase, K. & Ohno, H., 2014 12月 1, In: EMBO Reports. 15, 12, p. 1297-1304 8 p.

研究成果: Article › 査読

10 被引用数 (Scopus)

Epithelium-intrinsic MicroRNAs contribute to mucosal immune homeostasis by promoting M-cell maturation

Nakato, G., Hase, K., Sato, T., Kimura, S., Sakakibara, S., Sugiyama, M., Obata, Y., Hanazato, M., Iwanaga, T. & Ohno, H., 2016 3月, In: PloS one. 11, 3, e0150379.

研究成果: Article › 査読

11 被引用数 (Scopus)

Epoxyquinol B shows antiangiogenic and antitumor effects by inhibiting VEGFR2, EGFR, FGFR, and PDGFR

Kamiyama, H., Kakeya, H., Usui, T., Nishikawa, K., Shoji, M., Hayashi, Y. & Osada, H., 2008, In: Oncology research. 17, 1, p. 11-21 11 p.

研究成果: Article › 査読

13 被引用数 (Scopus)

Erratum to: LC-MS-based quantification method for Achyranthes root saponins

Kawahara, Y., Hoshino, T., Morimoto, H., Shimizu, T., Narukawa, Y., Fuchino, H., Kawahara, N. & Kiuchi, F., 2016 4月 1, In: Journal of Natural Medicines. 70, 2, p. 300 1 p.

研究成果: Article › 査読

Erythrocyte methotrexate-polyglutamate assay using fluorescence polarization immunoassay technique: Application to the monitoring of patients with rheumatoid arthritis

Inoue, S., Hashiguchi, M., Kawai, S. & Mochizuki, M., 2009 8月, In: Yakugaku Zasshi. 129, 8, p. 1001-1005 5 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Establishment and Long-Term Culture of Organoids Derived from Human Biliary Tract Carcinoma

Saito, Y., Muramatsu, T. & Saito, H., 2020 6月 19, In: STAR Protocols. 1, 1, 100009.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Establishment of a human cell line (HCC‐T) from a patient with hepatoma bearing no evidence of hepatitis B or A virus infection

Saito, H., Morizane, T., Watanabe, T., Kagawa, T., Iwabuchi, N., Kumagai, N., Inagaki, Y., Tsuchimoto, K. & Tsuchiya, M., 1989 9月 1, In: Cancer. 64, 5, p. 1054-1060 7 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Establishment of a human hepatoma cell line, HCC-T

Saito, H., Morizane, T., Matsumoto, S., Iwabuchi, N., Satoh, I., Oda, M., Tsuchiya, M., Watanabe, T. & Tsuzuki, T., 1988 1月 1, In: Nippon Shokakibyo Gakkai Zasshi. 85, 9, p. 1664-1671 8 p.

研究成果: Article › 査読

Establishment of an organoid bank of biliary tract and pancreatic cancers and its application for personalized therapy and future treatment

Saito, Y., 2019 1月 1, In: Journal of Gastroenterology and Hepatology (Australia).

研究成果: Article › 査読

11 被引用数 (Scopus)

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