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Article

Age-associated theophylline metabolic activity corresponds to the ratio of 1,3-dimethyluric acid to theophylline in mice

Kuroda, Y., Taguchi, K., Enoki, Y., Matsumoto, K., Hori, S. & Kizu, J., 2019, In: Biological and Pharmaceutical Bulletin. 42, 8, p. 1423-1427 5 p.

研究成果: Article › 査読

Open Access

Age-related changes in pharmacokinetic parameters of phenytoin after liver resection in rats

Nakashima, E., Matsushita, R., Iida, Y., Ohshima, T. & Ichimura, F., 1995, In: Pharmaceutical research. 12, 10, p. 1530-1534 5 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Age-Related Trends in Home Blood Pressure, Home Pulse Rate, and Day-to-Day Blood Pressure and Pulse Rate Variability Based on Longitudinal Cohort Data: The Ohasama Study

Satoh, M., Metoki, H., Asayama, K., Murakami, T., Inoue, R., Tsubota-Utsugi, M., Matsuda, A., Hirose, T., Hara, A., Obara, T., Kikuya, M., Nomura, K., Hozawa, A., Imai, Y. & Ohkubo, T., 2019 8 6, In: Journal of the American Heart Association. 8, 15, e012121.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

A Glucan Having Reticuloendothelial System-Potentiating and Anti-complementary Activities from the Tuber of Pinellia ternata

Tomoda, M., Gonda, R., Ōhara, N., Shimizu, N., Shishido, C. & Fujiki, Y., 1994, In: Biological and Pharmaceutical Bulletin. 17, 6, p. 859-861 3 p.

研究成果: Article › 査読

Open Access

9 被引用数 (Scopus)

A Glucan with Immunological Activities from the Tuber of Alisma orientale

Shimizu, N., Ohtsu, S., Tomoda, M., Gonda, R. & Ōhara, N., 1994 1 1, In: Biological and Pharmaceutical Bulletin. 17, 12, p. 1666-1668 3 p.

研究成果: Article › 査読

Open Access

14 被引用数 (Scopus)

Agonist-induced sequestration, recycling, and resensitization of platelet-activating factor receptor: Role of cytoplasmic tail phosphorylation in each process

Ishii, I., Saito, E., Izumi, T., Ui, M. & Shimizu, T., 1998 4 17, In: Journal of Biological Chemistry. 273, 16, p. 9878-9885 8 p.

研究成果: Article › 査読

59 被引用数 (Scopus)

A handy system for gel electrophoresis

Nishizawa, H. & Abe, Y., 1986, In: BUNSEKI KAGAKU. 35, 3

研究成果: Article › 査読

1 被引用数 (Scopus)

A highly active 4-siloxyproline catalyst for asymmetric synthesis

Hayashi, Y., Yamaguchi, J., Hibino, K., Sumiya, T., Urushima, T., Shoji, M., Hashizume, D. & Koshino, H., 2004 10 1, In: Advanced Synthesis and Catalysis. 346, 12, p. 1435-1439 5 p.

研究成果: Article › 査読

129 被引用数 (Scopus)

A historical review on International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) and internationalization of Japan's new drugs development and regulation

Kurokawa, T., 2014 1 1, In: Yakushigaku zasshi. The Journal of Japanese history of pharmacy. 49, 2, p. 165-170 6 p.

研究成果: Article › 査読

Airway M Cells arise in the lower airway due to RANKL signaling and reside in the bronchiolar epithelium associated with iBALT in murine models of respiratory disease

Kimura, S., Mutoh, M., Hisamoto, M., Saito, H., Takahashi, S., Asakura, T., Ishii, M., Nakamura, Y., Iida, J., Hase, K. & Iwanaga, T., 2019, In: Frontiers in Immunology. 10, JUN, 1323.

研究成果: Article › 査読

Open Access

11 被引用数 (Scopus)

Akt activation through the phosphorylation of erythropoietin receptor at tyrosine 479 is required for myeloproliferative disorder-associated JAK2 V617F mutant-induced cellular transformation

Kamishimoto, J., Tago, K., Kasahara, T. & Funakoshi-Tago, M., 2011 5, In: Cellular Signalling. 23, 5, p. 849-856 8 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization.

Fujita, N., Sato, S., Katayama, K. & Tsuruo, T., 2002 8 9, In: The Journal of biological chemistry. 277, 32, p. 28706-28713 8 p.

研究成果: Article › 査読

Open Access

285 被引用数 (Scopus)

Alanine exchanges of polar amino acids in the transmembrane domains of a platelet-activating factor receptor generate both constitutively active and inactive mutants

Ishii, I., Izumi, T., Tsukamoto, H., Umeyama, H., Ui, M. & Shimizuf, T., 1997, In: Journal of Biological Chemistry. 272, 12, p. 7846-7854 9 p.

研究成果: Article › 査読

55 被引用数 (Scopus)

Aldioxa improves delayed gastric emptying and impaired gastric compliance, pathophysiologic mechanisms of functional dyspepsia

Asano, T., Aida, S., Suemasu, S., Tahara, K., Tanaka, K. I. & Mizushima, T., 2015 12 1, In: Scientific reports. 5, 17519.

研究成果: Article › 査読

14 被引用数 (Scopus)

Aldolase Catalyzed Reaction for Carbohydrate Synthesis

Kajimoto, T., Sugai, T. & Wong, C. H., 1993 2 1, In: Trends in Glycoscience and Glycotechnology. 5, 23, p. 193-207 15 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

A lipidome atlas in MS-DIAL 4

Tsugawa, H., Ikeda, K., Takahashi, M., Satoh, A., Mori, Y., Uchino, H., Okahashi, N., Yamada, Y., Tada, I., Bonini, P., Higashi, Y., Okazaki, Y., Zhou, Z., Zhu, Z. J., Koelmel, J., Cajka, T., Fiehn, O., Saito, K., Arita, M. & Arita, M., 2020 10 1, In: Nature Biotechnology. 38, 10, p. 1159-1163 5 p.

研究成果: Article › 査読

80 被引用数 (Scopus)

Alkannin, HSP70 Inducer, Protects against UVB-Induced Apoptosis in Human Keratinocytes

Yoshihisa, Y., Hassan, M. A., Furusawa, Y., Tabuchi, Y., Kondo, T. & Shimizu, T., 2012 10 22, In: PloS one. 7, 10, e47903.

研究成果: Article › 査読

21 被引用数 (Scopus)

Alkylation of 2-phenylsulfinylethanol

Hiromichi, O., Shinsuke, M. & Takeshi, S., 1990, In: Tetrahedron Letters. 31, 20, p. 2895-2898 4 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Allosteric linkers in cAMP signalling

Akimoto, M., Moleschi, K., Boulton, S., VanSchouwen, B., Selvaratnam, R., Taylor, S. S. & Melacini, G., 2014 2, In: Biochemical Society Transactions. 42, 1, p. 139-144 6 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Alpha-ketoglutarate oxidoreductase, an essential salvage enzyme of energy metabolism, in coccoid form of Helicobacter pylori

Tsugawa, H., Suzuki, H., Nakagawa, I., Nishizawa, T., Saito, Y., Suematsu, M. & Hibi, T., 2008 11 7, In: Biochemical and Biophysical Research Communications. 376, 1, p. 46-51 6 p.

研究成果: Article › 査読

9 被引用数 (Scopus)

Alpha-tocopherol attenuates the anti-tumor activity of crizotinib against cells transformed by NPM-ALK

Uchihara, Y., Ueda, F., Tago, K., Nakazawa, Y., Ohe, T., Mashino, T., Yokota, S., Kasahara, T., Tamura, H. & Funakoshi-Tago, M., 2017 8, In: PloS one. 12, 8, e0183003.

研究成果: Article › 査読

10 被引用数 (Scopus)

Alteration in the contents of unsaturated fatty acids in dnaA mutants of Escherichia coli

Suzuki, E., Kondo, T., Makise, M., Mima, S., Sakamoto, K., Tsuchiya, T. & Mizushima, T., 1998, In: Molecular Microbiology. 28, 1, p. 95-102 8 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

Alterations in gene expression associated with the overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, during human hepatocarcinogenesis

Kanai, Y., Saito, Y., Ushijima, S. & Hirohashi, S., 2004 11, In: Journal of Cancer Research and Clinical Oncology. 130, 11, p. 636-644 9 p.

研究成果: Article › 査読

18 被引用数 (Scopus)

Alterations of epigenetics and microRNAs in cancer and cancer stem cell

Saito, Y., 2014, In: Frontiers in Genetics. 5, AUG, Article 283.

研究成果: Article › 査読

5 被引用数 (Scopus)

Altered expression and function of P-glycoprotein in dextran sodium sulfate-induced colitis in mice

Iizasa, H., Genda, N., Kitano, T., Tomita, M., Nishihara, K., Hayashi, M., Nakamura, K., Kobayashi, S. & Nakashima, E., 2003 3 1, In: Journal of Pharmaceutical Sciences. 92, 3, p. 569-576 8 p.

研究成果: Article › 査読

39 被引用数 (Scopus)

Altered expression of basement membrane-related molecules in rat brain pericyte, endothelial, and astrocyte cell lines after transforming growth factor-beta1 treatment.

Kose, N., Asashima, T., Muta, M., Iizasa, H., Sai, Y., Terasaki, T. & Nakashima, E., 2007 8, In: Drug Metabolism And Pharmacokinetics. 22, 4, p. 255-266 12 p.

研究成果: Article › 査読

27 被引用数 (Scopus)

Alveolar macrophages drive hepatocellular carcinoma lung metastasis by generating leukotriene B ₄

Nosaka, T., Baba, T., Tanabe, Y., Sasaki, S., Nishimura, T., Imamura, Y., Yurino, H., Hashimoto, S., Arita, M., Nakamoto, Y. & Mukaida, N., 2018 3 1, In: Journal of Immunology. 200, 5, p. 1839-1852 14 p.

研究成果: Article › 査読

19 被引用数 (Scopus)

A major component of vitamin E, α-tocopherol inhibits the anti-tumor activity of crizotinib against cells transformed by EML4-ALK

Uchihara, Y., Kidokoro, T., Tago, K., Mashino, T., Tamura, H. & Funakoshi-Tago, M., 2018 4 15, In: European journal of pharmacology. 825, p. 1-9 9 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

A Major Li⁺ Extrusion System NhaB of Pseudomonas aeruginosa: Comparison with the Major Na⁺ Extrusion System NhaP

Kuroda, T., Fujita, N., Utsugi, J., Kuroda, M., Mizushima, T. & Tsuchiya, T., 2004, In: Microbiology and Immunology. 48, 4, p. 243-250 8 p.

研究成果: Article › 査読

15 被引用数 (Scopus)

A MEK inhibitor, PD98059 enhances IL-1-induced NF-κB activation by the enhanced and sustained degradation of IκBα

Funakoshi, M., Tago, K., Sonoda, Y., Tominaga, S. I. & Kasahara, T., 2001, In: Biochemical and Biophysical Research Communications. 283, 1, p. 248-254 7 p.

研究成果: Article › 査読

33 被引用数 (Scopus)

Ameliorative effect of mepenzolate bromide against pulmonary fibrosiss

Kurotsu, S., Tanaka, K. I., Niino, T., Asano, T., Sugizaki, T., Azuma, A., Suzuki, H. & Mizushima, T., 2014 7, In: Journal of Pharmacology and Experimental Therapeutics. 350, 1, p. 79-88 10 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Ames test-negative carcinogen, ortho-phenyl phenol, binds tubulin and causes aneuploidy in budding yeast

Nunoshiba, T., Watanabe, E., Takahashi, T., Daigaku, Y., Ishikawa, S., Mochizuki, M., Ui, A., Enomoto, T. & Yamamoto, K., 2007 4 1, In: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 617, 1-2, p. 90-97 8 p.

研究成果: Article › 査読

12 被引用数 (Scopus)

A microRNA-27a mimic sensitizes human oral squamous cell carcinoma HSC-4 cells to hyperthermia through downregulation of Hsp110 and Hsp90

Kariya, A., Furusawa, Y., Yunoki, T., Kondo, T. & Tabuchi, Y., 2014 7, In: International journal of molecular medicine. 34, 1, p. 334-340 7 p.

研究成果: Article › 査読

17 被引用数 (Scopus)

A microscale synthesis of a promising radiolabelled antitumor drug: Cis‐1,1‐cyclobutanedicarboxylato (2R)‐2‐methyl‐1,4‐butanediamine platinum(II), NK121

Suwa, M., Kogawa, O., Nowatari, H., Murase, Y., Homma, Y. & Hashimoto, Y., 1992 5, In: Journal of Labelled Compounds and Radiopharmaceuticals. 31, 5, p. 349-354 6 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Amino acid-based diet prevents lethal infectious diarrhea by maintaining body water balance in a murine citrobacter rodentium infection model

Kimizuka, T., Seki, N., Yamaguchi, G., Akiyama, M., Higashi, S., Hase, K. & Kim, Y. G., 2021 6, In: Nutrients. 13, 6, 1896.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

A miRNA-based diagnostic model predicts resectable lung cancer in humans with high accuracy

Asakura, K., Kadota, T., Matsuzaki, J., Yoshida, Y., Yamamoto, Y., Nakagawa, K., Takizawa, S., Aoki, Y., Nakamura, E., Miura, J., Sakamoto, H., Kato, K., Watanabe, S. I. & Ochiya, T., 2020 12 1, In: Communications biology. 3, 1, 134.

研究成果: Article › 査読

Open Access

32 被引用数 (Scopus)

A misfolded dimer of Cu/Zn-superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis

Anzai, I., Tokuda, E., Mukaiyama, A., Akiyama, S., Endo, F., Yamanaka, K., Misawa, H. & Furukawa, Y., 2017 3 1, In: Protein Science. 26, 3, p. 484-496 13 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

A modified integral counting method and efficiency tracing method for measuring ²²²Rn by liquid-scintillation counting

Yoshio Homma, H., Yuko Murase, M. & Keiko Handa, H., 1994 6, In: Applied Radiation and Isotopes. 45, 6, p. 699-702 4 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Amounts of proteins altered by mutations in the dnaA gene of Escherichia coli

Ohba, A., Mizushima, T., Katayama, T. & Sekimizu, K., 1997 3 10, In: FEBS Letters. 404, 2-3, p. 125-128 4 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

A mouse model reveals that Mfsd2a is critical for unfolded protein response upon exposure to tunicamycin

Moritake, H., Obara, M., Saito, Y., Kashimada, A., Takagi, M., Funakoshi-Tago, M., Fukuyama, T., Yoshioka, M., Inoue, A., Komatsu, H., Nishitoh, H., Kataoka, H. & Nunoi, H., 2017 4 1, In: Human Cell. 30, 2, p. 88-97 10 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

A mucilage from Hibiscus moscheutos leaves

Tomoda, M., Gonda, R., Shimizu, N., Nakanishi, S. & Hikino, H., 1987, In: Phytochemistry. 26, 8, p. 2297-2300 4 p.

研究成果: Article › 査読

8 被引用数 (Scopus)

An Acidic Polysaccharide Having Activity on the Reticuloendothelial System from the Bark of Eucommia ulmoides

Gonda, R., Tomoda, M., Shimizu, N. & Kanari, M., 1990, In: Chemical and Pharmaceutical Bulletin. 38, 7, p. 1966-1969 4 p.

研究成果: Article › 査読

Open Access

23 被引用数 (Scopus)

An Acidic Polysaccharide Having Activity on the Reticuloendothelial System from the Root of Astragalus mongholicus

Shimizu, N., Tomoda, M., Kanari, M. & Gonda, R., 1991, In: Chemical and Pharmaceutical Bulletin. 39, 11, p. 2969-2972 4 p.

研究成果: Article › 査読

Open Access

62 被引用数 (Scopus)

An Acidic Polysaccharide Having Activity on the Reticuloendothelial System from the Roots and Rhizomes of Saposhnikovia divaricata

Shimizu, N., Tomoda, M., Gonda, R. & Kanari, M., 1989, In: Chemical and Pharmaceutical Bulletin. 37, 11, p. 3054-3057 4 p.

研究成果: Article › 査読

Open Access

22 被引用数 (Scopus)

An Acidic Polysaccharide Having Immunological Activities from the Rhizome of Cnidium officinale

Tomoda, M., Ohara, N., Gonda, R., Shimizu, N., Takada, K., Satoh, Y. & Shirai, S., 1992, In: Chemical and Pharmaceutical Bulletin. 40, 11, p. 3025-3029 5 p.

研究成果: Article › 査読

Open Access

15 被引用数 (Scopus)

An Acidic Polysaccharide with Immunological Activities from the Root of Paeonia lactiflora

Tomoda, M., Matsumoto, K., Shimizu, N., Gonda, R., Ohara, N. & Hirabayashi, K., 1994 1 1, In: Biological and Pharmaceutical Bulletin. 17, 9, p. 1161-1164 4 p.

研究成果: Article › 査読

Open Access

16 被引用数 (Scopus)

Analyses of lipid a diversity in gram-negative intestinal bacteria using liquid chromatography–quadrupole time-of-flight mass spectrometry

Okahashi, N., Ueda, M., Matsuda, F. & Arita, M., 2021 4, In: Metabolites. 11, 4, 197.

研究成果: Article › 査読

Open Access

Analysis of antipyretics by semimicro liquid chromatography

Matsushima, Y., Nagata, Y., Niyomura, M., Takakusagi, K. & Takai, N., 1985 9 20, In: Journal of Chromatography A. 332, C, p. 269-273 5 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Analysis of benzimidazole anthelmintics in livestock foods by HPLC/MS/MS

Kai, S., Akaboshi, T., Kishi, M., Kanazawa, H. & Kobayashi, S., 2005, In: BUNSEKI KAGAKU. 54, 9, p. 775-782 8 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Analysis of formaldehyde, acetaldehyde and oligomers in recycled polyethylene terephthalate

Ohkado, Y., Kawamura, Y., Mutsuga, M., Tamura, H. O. & Tanamoto, K., 2005 10, In: Journal of the Food Hygienic Society of Japan. 46, 5, p. 218-223 6 p.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

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