薬学部

Article

Rat Kupffer cell-derived nitric oxide suppresses proliferation and induces apoptosis of syngeneic hepatoma cells

Kurose, I., Higuchi, H., Yonei, Y., Ebinuma, H., Watanabe, N., Hokari, R., Fukumura, D., Miura, S., Takaishi, M., Saito, H., Nakatsumi, R. C. & Ishii, H., 1996 1月 1, In: Gastroenterology. 111, 4, p. 1058-1070 13 p.

研究成果: Article › 査読

26 被引用数 (Scopus)

Reaction monitoring of tocopherols with active nitrogen oxides by ultra high-speed liquid chromatography

Nagata, Y., Nishio, T. & Kanazawa, H., 2011 5月 15, In: Journal of Pharmaceutical and Biomedical Analysis. 55, 2, p. 241-246 6 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Reaction of 2,2,5,7,8-pentamethyl-6-chromanol, an α-tocopherol analogue, with NO in the presence of oxygen

Nagata, Y., Nishio, T., Matsumoto, S., Kanazawa, H., Mochizuki, M. & Matsushima, Y., 2000 12月 18, In: Bioorganic and Medicinal Chemistry Letters. 10, 24, p. 2709-2712 4 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Reactive oxygen species-induced autophagic degradation of helicobacter pylori CagA is specifically suppressed in cancer stem-like cells

Tsugawa, H., Suzuki, H., Saya, H., Hatakeyama, M., Hirayama, T., Hirata, K., Nagano, O., Matsuzaki, J. & Hibi, T., 2012 12月 13, In: Cell Host and Microbe. 12, 6, p. 764-777 14 p.

研究成果: Article › 査読

169 被引用数 (Scopus)

Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by 1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress

Shinkai, Y., Abiko, Y., Ida, T., Miura, T., Kakehashi, H., Ishii, I., Nishida, M., Sawa, T., Akaike, T. & Kumagai, Y., 2015 5月 18, In: Chemical Research in Toxicology. 28, 5, p. 838-847 10 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Realization of the synthesis of α,α-disubstituted carbamylacetates and cyanoacetates by either enzymatic or chemical functional group transformation, depending upon the substrate specificity of Rhodococcus amidase

Yokoyama, M., Kashiwagi, M., Iwasaki, M., Fuhshuku, K. I., Ohta, H. & Sugai, T., 2004 9月 20, In: Tetrahedron Asymmetry. 15, 18, p. 2817-2820 4 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

Real-time in situ X-ray micro-computed tomography study of the effect of impurities on the crystallization of amorphous nifedipine

Amano, Y., Misawa, T., Miyazaki, T., Ando, D., Koide, T., Izutsu, K. I., Kanazawa, H., Hanaoka, K. & Yamamoto, E., 2023 3月 20, In: Journal of Pharmaceutical and Biomedical Analysis. 226, 115248.

研究成果: Article › 査読

Real-Time Survey of Vaccine Safety of the mRNA-1273 SARS-CoV-2 Vaccine in Workplace Vaccination at Keio University

Okumura, K., Hara, A., Inada, I., Sugiyama, D., Hoshino, T., Yakoh, T., Yokoyama, H. & Urushihara, H., 2022 9月, In: Vaccines. 10, 9, 1461.

研究成果: Article › 査読

Open Access

Real-world evidence of galcanezumab for migraine treatment in Japan: a retrospective analysis

Takizawa, T., Ohtani, S., Watanabe, N., Miyazaki, N., Ishizuchi, K., Sekiguchi, K., Iba, C., Shibata, M., Takemura, R., Hori, S. & Nakahara, J., 2022 12月, In: BMC Neurology. 22, 1, 512.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

Real World Survey of Patient Engagement Status in Clinical Research: The First Input from Japan

Tanemura, N., Sasaki, T., Sato, J. & Urushihara, H., 2020 10月 1, In: Patient. 13, 5, p. 623-632 10 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Reappraisal of VAChT-Cre: Preference in slow motor neurons innervating type I or IIa muscle fibers

Misawa, H., Inomata, D., Kikuchi, M., Maruyama, S., Moriwaki, Y., Okuda, T., Nukina, N. & Yamanaka, T., 2016 11月 1, In: Genesis. 54, 11, p. 568-572 5 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Recent Advances in the Study of Hepatocellular Carcinoma

Saito, H. & Tsuchiya, M., 1992, In: Keio Journal of Medicine. 41, 4, p. 195-204 10 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Recent trends for drug lag in clinical development of oncology drugs in Japan: does the oncology drug lag still exist in Japan?

Maeda, H. & Kurokawa, T., 2015 12月 1, In: International Journal of Clinical Oncology. 20, 6, p. 1072-1080 9 p.

研究成果: Article › 査読

31 被引用数 (Scopus)

Reciprocal regulation of STING and TCR signaling by mTORC1 for T-cell activation and function

Imanishi, T., Unno, M., Kobayashi, W., Yoneda, N., Matsuda, S., Ikeda, K., Hoshii, T., Hirao, A., Miyake, K., Barber, G. N., Arita, M., Ishii, K. J., Akira, S. & Saito, T., 2019, In: Life Science Alliance. 2, 1, e201800282.

研究成果: Article › 査読

Open Access

27 被引用数 (Scopus)

Recognition of the remote chiral center in lipase-catalyzed kinetic resolution of [2-methyl-2-(2′-naphthyl)-1,3-benzodioxol-4-yl]methyl acetate, the precursor of 2-methyl-2-(2′-naphthyl)-1,3-benzodioxole-4-carboxylic acid (MNB carboxylic acid)

Natori, N., Nakagawara, K., Shoji, M., Sugai, T. & Hanaya, K., 2014 11月, In: Journal of Molecular Catalysis B: Enzymatic. 109, p. 130-135 6 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Reconciling neuronally and nonneuronally derived acetylcholine in the regulation of immune function

Kawashima, K., Fujii, T., Moriwaki, Y., Misawa, H. & Horiguchi, K., 2012 7月, In: Annals of the New York Academy of Sciences. 1261, 1, p. 7-17 11 p.

研究成果: Article › 査読

61 被引用数 (Scopus)

Recurrence of autoimmune disease after autologous peripheral blood stem cell transplantation for multiple myeloma

Isshiki, I., Okamoto, S., Kakimoto, T., Chen, C. K., Mori, T., Yokoyama, K., Hattori, Y. & Ikeda, Y., 2006 11月, In: International journal of hematology. 84, 4, p. 354-358 5 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Reduced in vitro immunoglobulin secretion from peripheral blood mononuclear cells in responders to high-dose interferon-α2b treatment for chronic hepatitis C

Atsukawa, K., Saito, H., Ebinuma, H., Morizane, T., Takahashi, M., Ohishi, T., Kumagai, N., Tsuchimoto, K. & Ishii, H., 2000 12月 27, In: Hepato-gastroenterology. 47, 36, p. 1685-1690 6 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Reduction in blood pressure and vascular reactivities to pressor substances by chronic treatment with piretanide in spontaneously hypertensive rats

Kawashima, K., Hayakawa, T., Oohata, H., Fujimoto, K. & Suzuki, T., 1989, In: General Pharmacology. 20, 2, p. 213-217 5 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Reduction of acetophenones with methyl fluorines and a bulky group on the aromatic ring using microorganisms and related enzymes

Abe, C., Sugawara, T., MacHida, T., Higashi, T., Hanaya, K., Shoji, M., Cao, C., Yamamoto, T., Matsuda, T. & Sugai, T., 2012 10月, In: Journal of Molecular Catalysis B: Enzymatic. 82, p. 86-91 6 p.

研究成果: Article › 査読

5 被引用数 (Scopus)

Reduction of Acyl Enolates of α-Substituted β-Keto Esters by Bakers' Yeast

Ohta, H., Kobayashi, N. & Sugai, T., 1990, In: Agricultural and biological chemistry. 54, 2, p. 489-493 5 p.

研究成果: Article › 査読

11 被引用数 (Scopus)

Reduction of c-myc expression by an antisense approach under Cre/IoxP switching induces apoptosis in human liver cancer cells

Ebinuma, H., Saito, H., Kosuga, M., Wakabayashi, K., Saito, Y., Takagi, T., Nakamoto, N., Okuyama, T. & Ishii, H., 2001 6月 6, In: Journal of Cellular Physiology. 188, 1, p. 56-66 11 p.

研究成果: Article › 査読

21 被引用数 (Scopus)

Reduction of LAK-sensitivity and changes in antigen expression on hepatoma cells by sodium butyrate

Tada, S., Saito, H., Ebinuma, H., Atsukawa, K., Masuda, T., Tsunematsu, S., Morizane, T. & Ishii, H., 1996 4月 1, In: Cancer Biochemistry Biophysics. 15, 3, p. 177-186 10 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Reduction of lipid accumulation rescues Bietti's crystalline dystrophy phenotypes

Hata, M., Ikeda, H. O., Iwai, S., Iida, Y., Gotoh, N., Asaka, I., Ikeda, K., Isobe, Y., Hori, A., Nakagawa, S., Yamato, S., Arita, M., Yoshimura, N. & Tsujikawa, A., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 15, p. 3936-3941 6 p.

研究成果: Article › 査読

Open Access

34 被引用数 (Scopus)

Reduction of telomerase activity in human liver cancer cells by a histone deacetylase inhibitor

Nakamura, M., Saito, H., Ebinuma, H., Wakabayashi, K., Saito, Y., Takagi, T., Nakamoto, N. & Ishii, H., 2001 5月 8, In: Journal of Cellular Physiology. 187, 3, p. 392-401 10 p.

研究成果: Article › 査読

35 被引用数 (Scopus)

Reductive Conversion of Carbonyl Compounds by Yeast. Part II. Improved Conditions for the Production and Characterization of 1-Arylpropane-1,2-Diols and Related Compounds

Mochizuki, N., Hiramatsu, S., Sugai, T., Ohta, H., Morita, H. & Itokawa, H., 1995, In: Bioscience, Biotechnology, and Biochemistry. 59, 12, p. 2282-2291 10 p.

研究成果: Article › 査読

24 被引用数 (Scopus)

Reelin deficiency leads to aberrant lipid composition in mouse brain

Mizukami, T., Ikeda, K., Shimanaka, Y., Korogi, K., Zhou, C., Takase, H., Tsuiji, H., Kono, N., Kohno, T., Arai, H., Arita, M. & Hattori, M., 2018 10月 20, In: Biochemical and Biophysical Research Communications. 505, 1, p. 81-86 6 p.

研究成果: Article › 査読

3 被引用数 (Scopus)

Regio- and chemoselective manipulation under mild conditions on glucosamine derivatives for oligosaccharide synthesis and its application toward N-acetyl-d-lactosamine and Lewis X trisaccharide

Nagai, Y., Ito, N., Sultana, I. & Sugai, T., 2008 9月 29, In: Tetrahedron. 64, 40, p. 9599-9606 8 p.

研究成果: Article › 査読

14 被引用数 (Scopus)

Regio- And Stereoselective Hydrogenation of 2-demethoxy-2’-methyldehydrogriseofulvin, A Symmetrical Substrate, To (+)-2-demethoxy-2^/-methylgriseofulvin With A Cell-free System of Streptomyces Cinereocrocatus

Oda, T., Hashimoto, H. & Sato, Y., 1990 1月 1, In: Chemical and Pharmaceutical Bulletin. 38, 2, p. 525-528 4 p.

研究成果: Article › 査読

Open Access

3 被引用数 (Scopus)

Regional differences in extracellular choline dependency of acetylcholine synthesis in the rat brain

Suzuki, T., Kashima, Y., Fujimoto, K., Oohata, H. & Kawashima, K., 1991 6月, In: Neuroscience Research. 11, 1, p. 71-76 6 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Region- and isoform-specific expression of hydroxysteroid sulfotransferases in rat brain

Shimizu, M., Nakano, Y., Yamasaki, T., Kimoto, T., Kawato, S. & Tamura, H. O., 2004 12月, In: Journal of Health Science. 50, 6, p. 689-692 4 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Regorafenib-induced hand-foot skin reaction is more severe on the feet than on the hands

Nonomiya, Y., Yokokawa, T., Kawakami, K., Kobayashi, K., Aoyama, T., Takiguchi, T., Sugisaki, T., Suzuki, K., Suenaga, M., Wakatsuki, T., Yamaguchi, K., Sugimoto, Y. & Hama, T., 2019, In: Oncology research. 27, 5, p. 551-556 6 p.

研究成果: Article › 査読

Open Access

5 被引用数 (Scopus)

Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study

Yamada, S., Komiyama, T., Ohi, T., Murakami, T., Miyoshi, Y., Endo, K., Hiratsuka, T., Hara, A., Satoh, M., Tatsumi, Y., Inoue, R., Asayama, K., Kikuya, M., Hozawa, A., Metoki, H., Imai, Y., Ohkubo, T. & Hattori, Y., 2022 6月, In: Journal of Periodontal Research. 57, 3, p. 615-622 8 p.

研究成果: Article › 査読

Open Access

2 被引用数 (Scopus)

Regulation of inflammatory response of macrophages and induction of regulatory T cells by using retinoic acid-loaded nanostructured lipid carrier

Zai, K., Ishihara, N., Oguchi, H., Hirota, M., Kishimura, A., Mori, T., Hase, K. & Katayama, Y., 2019 1月 2, In: Journal of Biomaterials Science, Polymer Edition. 30, 1, p. 1-11 11 p.

研究成果: Article › 査読

4 被引用数 (Scopus)

Regulation of the membrane trafficking of the mechanosensitive ion channels trpv1 and trpv4 by zonular tension, osmotic stress and activators in the mouse lens

Nakazawa, Y., Petrova, R. S., Sugiyama, Y., Nagai, N., Tamura, H. & Donaldson, P. J., 2021 12月 1, In: International journal of molecular sciences. 22, 23, 12658.

研究成果: Article › 査読

Open Access

6 被引用数 (Scopus)

Regulatory review time for approval of oncology drugs in Japan between 2001 and 2014. Considerations of changes, factors that affect review time, and difference with the United States

Maeda, H. & Kurokawa, T., 2015 5月 1, In: Journal of Clinical Pharmacology. 55, 5, p. 481-489 9 p.

研究成果: Article › 査読

16 被引用数 (Scopus)

Relationship between chemical structure and activating potencies of complement by an acidic polysaccharide, plantago-mucilage A, from the seed of Plantago asiatica

Yamada, H., Nagai, T., Cyong, J. C., Otsuka, Y., Tomoda, M., Shimizu, N. & Gonda, R., 1986 11月 15, In: Carbohydrate Research. 156, C, p. 137-145 9 p.

研究成果: Article › 査読

29 被引用数 (Scopus)

Relationship between Cytotoxic and Microtubule Disruptive Activities of (+)-, (-)- and (±)-Indenestrol A and B Monomethyl Ethers in Chinese Hamster V79 Cells in Culture

Oda, T., Aizu-Yokota, E., Kitaoka, M. & Sato, Y., 1995 1月 1, In: Biological and Pharmaceutical Bulletin. 18, 6, p. 818-824 7 p.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Relationship between genetic polymorphisms and mRNA expression of dihydrofolate reductase enzyme in a healthy Japanese population

Hashiguchi, M., Shimizu, M., Takeuchi, O., Hayashi, T., Inoue, S., Tanaka, T., Tsuru, T., Irie, S., Kurokawa, T. & Mochizuki, M., 2013 5月, In: Japanese Journal of Clinical Pharmacology and Therapeutics. 44, 3, p. 185-192 8 p.

研究成果: Article › 査読

Relationship between medication adherence and glycemic control in Japanese patients with type 2 diabetes

Tominaga, Y., Aomori, T., Hayakawa, T., Morisky, D. E., Takahashi, K. & Mochizuki, M., 2018, In: Pharmazie. 73, 10, p. 609-612 4 p.

研究成果: Article › 査読

6 被引用数 (Scopus)

Relationships between the hepatic intrinsic clearance or blood cell-plasma partition coefficient in the rabbit and the lipophilicity of basic drugs

Ishizaki, J., Yokogawa, K., Nakashima, E. & Ichimura, F., 1997 8月, In: Journal of Pharmacy and Pharmacology. 49, 8, p. 768-772 5 p.

研究成果: Article › 査読

22 被引用数 (Scopus)

Relationships in the Structure–Tissue Distribution of Basic Drugs in the Rabbit

Yokogawa, K., Nakashima, E., Ishizaki, J., Maeda, H., Nagano, T. & Ichimura, F., 1990 7月, In: Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 7, 7, p. 691-696 6 p.

研究成果: Article › 査読

74 被引用数 (Scopus)

Relative contributions of metabolic enzymes to systemic elimination can be estimated from clinical DDI studies: Validation using an in silico approach

Koinuma, K., Tsuchitani, T., Imaoka, A., Akiyoshi, T. & Ohtani, H., 2021 3月, In: International journal of clinical pharmacology and therapeutics. 59, 3, p. 231-238 8 p.

研究成果: Article › 査読

1 被引用数 (Scopus)

Relative Rank-order of Salient Identities of the Japanese

Uemura, R., 2011 11月, In: International Journal of Japanese Sociology. 20, 1, p. 73-88 16 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Relaxation of supercoiled DNA associated with induction of heat shock proteins in Escherichia coli

Mizushima, T., Natori, S. & Sekimizu, K., 1993 4月 1, In: MGG Molecular & General Genetics. 238, 1-2, p. 1-5 5 p.

研究成果: Article › 査読

59 被引用数 (Scopus)

Remarkable synergies between baicalein and tetracycline, and baicalein and β-lactams against methicillin-resistant Staphylococcus aureus

Fujita, M., Shiota, S., Kuroda, T., Hatano, T., Yoshida, T., Mizushima, T. & Tsuchiya, T., 2005, In: Microbiology and Immunology. 49, 4, p. 391-396 6 p.

研究成果: Article › 査読

120 被引用数 (Scopus)

Remdesivir for the treatment of coronavirus COVID-19: A meta-analysis of randomised controlled trials

Enoki, Y., Igarashi, Y., Watabe, Y., Honma, K., Suzuki, Y., Hayashi, Y., Hiraoka, K., Taguchi, K. & Matsumoto, K., 2021 3月, In: Journal of Global Antimicrobial Resistance. 24, p. 81-82 2 p.

研究成果: Article › 査読

Open Access

4 被引用数 (Scopus)

Removal of radiocesium using cation exchange resin

Morita-Murase, Y., Mizumura, R., Tachibana, Y. & Kanazawa, H., 2013 6月 27, In: BUNSEKI KAGAKU. 62, 6, p. 541-545 5 p.

研究成果: Article › 査読

2 被引用数 (Scopus)

Renal dysfunction and anemia associated with long-term imatinib treatment in patients with chronic myelogenous leukemia

Sakurai, M., Kikuchi, T., Karigane, D., Kasahara, H., Matsuki, E., Hashida, R., Yamane, Y., Abe, R., Koda, Y., Toyama, T., Kato, J., Shimizu, T., Yokoyama, Y., Suzuki, S., Nakamura, T., Okamoto, S. & Mori, T., 2019 3月 20, In: International journal of hematology. 109, 3, p. 292-298 7 p.

研究成果: Article › 査読

7 被引用数 (Scopus)

Renin-Angiotensin-Aldosterone System Inhibitors Prevent the Onset of Oxaliplatin-Induced Peripheral Neuropathy: A Retrospective Multicenter Study and in Vitro Evaluation

Uchida, M., Ushio, S., Niimura, T., Takechi, K., Kawazoe, H., Hidaka, N., Tanaka, A., Araki, H., Zamami, Y., Ishizawa, K., Kitamura, Y., Sendou, T., Kawasaki, H., Namba, H., Shibata, K., Tanaka, M. & Takatori, S., 2022 2月, In: Biological and Pharmaceutical Bulletin. 45, 2, p. 226-234 9 p.

研究成果: Article › 査読

Open Access

1 被引用数 (Scopus)

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