年別の研究成果
年別の研究成果
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1991
High-performance liquid chromatography of saponins of crude drugs on chemically modified porous glass
Kanazawa, H., Nagata, Y., Matsushima, Y., Tomada, M. & Takai, N., 1991 6月 28, In: Journal of Pharmacobio-Dynamics. 14, 4, p. s-84研究成果: Article › 査読
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Intermediate species absorbing in the 500-nm region in metal ion mediated pyridoxal catalysis
Matsushima, Y., Nagata, Y. & Kojima, M., 1991 12月 1, In: Journal of Pharmacobio-Dynamics. 14, 11, p. s-116研究成果: Article › 査読
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Lipase-mediated efficient preparation of both enantiomers of 2-acetoxytetracosanoic acid, the intermediate for sphingolipid synthesis
Sugai, T. & Ohta, H., 1991 11月 25, In: Tetrahedron Letters. 32, 48, p. 7063-7064 2 p.研究成果: Article › 査読
29 被引用数 (Scopus) -
Microbial hydrolysis as a potent method for the preparation of optically active nitriles, amides and carboxylic acids
Kakeya, H., Sakai, N., Sugai, T. & Ohta, H., 1991 3月 4, In: Tetrahedron Letters. 32, 10, p. 1343-1346 4 p.研究成果: Article › 査読
112 被引用数 (Scopus) -
Preparation of Optically Active α-Hydroxy Acid Derivatives by Microbial Hydrolysis of Cyanohydrins and Its Application to the Synthesis of (R)-4-Dodecanolide†
Kakeya, H., Sakai, N., Sugai, T. & Ohta, H., 1991, In: Agricultural and biological chemistry. 55, 7, p. 1877-1881 5 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Preparation of optically active α-hydroxy acid derivatives by microbial hydrolysis of cyanohydrins and its application to the synthesis of (R)-4-dodeeanolide
Kakeya, H., Sakai, N., Sugai, T. & Ohta, H., 1991 7月, In: Agricultural and biological chemistry. 55, 7, p. 1877-1881 5 p.研究成果: Article › 査読
32 被引用数 (Scopus) -
Studies on catecholamine by HPLC with multi ECD
Takai, N., Shinozuka, N., Mashige, F., Ohkubo, A., Nukina, N., Iijima, S., Fukui, Y., Sakuma, I., Itou, F., Matsushima, Y. & Nagata, Y., 1991 1月, In: analytical sciences. 7, p. 955-956 2 p.研究成果: Article › 査読
Open Access -
1992
RHO gene products, putative small GTP‐binding proteins, are importnat for activation of the CAL1/CDC43 gene product, a protein geranylgeranyltransferase in Saccharomyces cerevisiae
Qadota, H., Ishii, I., Fujiyama, A., Ohya, Y. & Anraku, Y., 1992 9月, In: Yeast. 8, 9, p. 735-741 7 p.研究成果: Article › 査読
53 被引用数 (Scopus) -
Synthesis of the (4R,5R)-Isomer of 5-Hydroxy-6-phenyl-4-hexanolide, a Lateral Root-inducing Substance Isolated from Erwinia quercina
Sugai, T., Noguchi, H. & Ohta, H., 1992 1月 1, In: Bioscience, Biotechnology, and Biochemistry. 56, 1, p. 122-126 5 p.研究成果: Article › 査読
7 被引用数 (Scopus) -
1993
Aldolase Catalyzed Reaction for Carbohydrate Synthesis
Kajimoto, T., Sugai, T. & Wong, C. H., 1993 2月 1, In: Trends in Glycoscience and Glycotechnology. 5, 23, p. 193-207 15 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Asymmetric hydrolysis of a disubstituted malononitrile by the aid of a microorganism
Yokoyama, M., Sugai, T. & Ohta, H., 1993 6月, In: Tetrahedron: Asymmetry. 4, 6, p. 1081-1084 4 p.研究成果: Article › 査読
47 被引用数 (Scopus) -
A synthesis of (R-recifeiolide by the aid of biochemical reaction as the key-step
Mochizuki, N., Yamada, H., Sugai, T. & Ohta, H., 1993 7月, In: Bioorganic and Medicinal Chemistry. 1, 1, p. 71-75 5 p.研究成果: Article › 査読
14 被引用数 (Scopus) -
Isolation and Identification of Canine Plasma Components Suspected as Uremic Toxins
Kawamura, M., Motoie, H., Nishimura, R., Sasaki, N., Takeuchi, A., Ohashi, F., Nagata, Y. & Takai, N., 1993, In: Journal of Veterinary Medical Science. 55, 2, p. 265-270 6 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Presence of the factor that inhibits collagen synthesis and stimulates cell proliferation in developing embryonic chick skin extracts
Tajima, S., Ohyama, K., Tokimitsu, I. & Takehana, M., 1993 12月, In: Journal of Dermatological Science. 6, 3, p. 258-260 3 p.研究成果: Article › 査読
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Solvolysis of Pyridoxal Hydrochloride in Alcohols
Nagata, Y., Yoda, R. & Matsushima, Y., 1993, In: Chemical and Pharmaceutical Bulletin. 41, 6, p. 1019-1022 4 p.研究成果: Article › 査読
Open Access4 被引用数 (Scopus) -
1994
Application of microbial enantiofacially selective hydrolysis in natural product synthesis
Katoh, O., Sugai, T. & Ohta, H., 1994 10月, In: Tetrahedron: Asymmetry. 5, 10, p. 1935-1944 10 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
Biochemical Reduction of 3-Oxoalkanoic Esters by a Bottom-fermentation Yeast, Saccharomyces cerevisiae IFO 0565
Mochizuki, N., Sugai, T. & Ohta, H., 1994, In: Bioscience, Biotechnology, and Biochemistry. 58, 9, p. 1666-1670 5 p.研究成果: Article › 査読
21 被引用数 (Scopus) -
High-performance liquid chromatographic determination of catecholamine metabolites and 5-hydroxyindoleacetic acid in human urine using a mixed-mode column and an eight-channel electrode electrochemical detector
Mashige, F., Ohkubo, A., Matsushima, Y., Takano, M., Tsuchiya, E., Kanazawa, H., Nagata, Y., Takai, N., Shinozuka, N. & Sakuma, I., 1994 8月 5, In: Journal of Chromatography B: Biomedical Sciences and Applications. 658, 1, p. 63-68 6 p.研究成果: Article › 査読
32 被引用数 (Scopus) -
Identification of nondisulfided proα1(IV) chain produced by cultured B16 melanoma cells
Tokimitsu, I., Takehana, M., Hori, H., Nagai, Y. & Tajima, S., 1994 11月, In: Journal of biochemistry. 116, 5, p. 1039-1043 5 p.研究成果: Article › 査読
4 被引用数 (Scopus) -
Possible involvement of GTP-Binding proteins in 1α,25-Dihydroxyvitamin D3 induction of tissue transglutaminase in mouse peritoneal macrophages
Ishii, I. & Ui, M., 1994 9月 30, In: Biochemical and Biophysical Research Communications. 203, 3, p. 1773-1780 8 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
POSSIBLE ROLE OF METALLOTHIONEIN IN THE CELLULAR DEFENSE MECHANISM AGAINST UVB IRRADIATION IN NEONATAL HUMAN SKIN FIBROBLASTS
Kobayashi, S., Hirota, Y., Sayato‐Suzuki, J., Takehana, M., Nishimura, H., Nishimura, N. & Tohyama, C., 1994 6月, In: Photochemistry and Photobiology. 59, 6, p. 650-656 7 p.研究成果: Article › 査読
20 被引用数 (Scopus) -
Retinoic acid-induced gene expression of tissue transglutaminase via protein kinase c-dependent pathway in mouse peritoneal macrophages
Ishii, I. & Ui, M., 1994 6月, In: Journal of biochemistry. 115, 6, p. 1197-1202 6 p.研究成果: Article › 査読
6 被引用数 (Scopus) -
1995
Biocatalysts-Mediated Preparation of Optically Active Hydroxy Acids
Sugai, T., Tsuchiya, S., Ohta, H. & Mochizuki, N., 1995, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 53, 1, p. 32-42 11 p.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Biochemical Asymmetric Synthesis and Its Application to Chemical Synthesis of Bioactive Compounds
Sugai, T., 1995, In: nippon nogeikagaku kaishi. 69, 1, p. 9-16 8 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Chemo-enzymatic synthesis of (R,R)-(-)-Pyrenophorin
Sugai, T., Katoh, O. & Ohta, H., 1995 10月 30, In: Tetrahedron. 51, 44, p. 11987-11998 12 p.研究成果: Article › 査読
54 被引用数 (Scopus) -
Determination of medetomidine, atipamezole and midazolam in pig plasma by liquid chromatography‐mass spectrometry
Kanazawa, H., Nishimura, R., Sasaki, N., Takeuchi, A., Takai, N., Nagata, Y. & Matsushima, Y., 1995 1月 1, In: Biomedical Chromatography. 9, 4, p. 188-191 4 p.研究成果: Article › 査読
27 被引用数 (Scopus) -
Improved enzymatic procedure for a preparative-scale synthesis of sialic acid and KDN
Sugai, T., Kuboki, A., Hiramatsu, S., Okazaki, H. & Ohta, H., 1995 12月 1, In: Bulletin of the Chemical Society of Japan. 68, 12, p. 3581-3589 9 p.研究成果: Article › 査読
42 被引用数 (Scopus) -
Post-translational regulation of type I collagen synthesis by heparin in vascular smooth muscle cells
Tajima, S., Wachi, H. & Takehan, M., 1995 2月, In: Journal of biochemistry. 117, 2, p. 353-358 6 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
Prodrugs of vitamin E. 1. Preparation and enzymatic hydrolysis of aminoalkanecarboxylic acid esters of d‐α‐tocopherol
Takata, J., Karube, Y., Nagata, Y. & Matsushima, Y., 1995 1月, In: Journal of Pharmaceutical Sciences. 84, 1, p. 96-100 5 p.研究成果: Article › 査読
29 被引用数 (Scopus) -
Protective Effects of Glutathione Isopropyl Ester on the Sensitivity of Cultured Cells to UVB Irradiation
Kobayashi, S., Satoh, H. & Takehana, M., 1995 1月 1, In: Biological and Pharmaceutical Bulletin. 18, 9, p. 1219-1222 4 p.研究成果: Article › 査読
Open Access5 被引用数 (Scopus) -
Reductive Conversion of Carbonyl Compounds by Yeast. Part II. Improved Conditions for the Production and Characterization of 1-Arylpropane-1,2-Diols and Related Compounds
Mochizuki, N., Hiramatsu, S., Sugai, T., Ohta, H., Morita, H. & Itokawa, H., 1995, In: Bioscience, Biotechnology, and Biochemistry. 59, 12, p. 2282-2291 10 p.研究成果: Article › 査読
24 被引用数 (Scopus) -
Simultaneous determination of catecholamines, their basic metabolites and serotonin in urine by high‐performance liquid chromatography using A mixed‐mode column and an eight‐channel electrochemical detector
Mashige, F., Matsushima, Y., Miyata, C., Yamada, R., Kanazawa, H., Sakuma, I., Takai, N., Shinozuka, N., Ohkubo, A. & Nakahara, K., 1995, In: Biomedical Chromatography. 9, 5, p. 221-225 5 p.研究成果: Article › 査読
49 被引用数 (Scopus) -
1996
Acidic catecholamine metabolites and 5-hydroxyindoleacetic acid in urine: The influence of diet
Mashige, F., Matsushima, Y., Kanazawa, H., Sakuma, I., Takai, N., Bessho, F. & Ohkubo, A., 1996, In: Annals of Clinical Biochemistry. 33, 1, p. 43-49 7 p.研究成果: Article › 査読
31 被引用数 (Scopus) -
Action of nitrile hydratase from rhodococcus rhodochrous IFO 15564 on Derivatives of 2,5-Anhydro-d-allononitrile
Yokoyama, M., Nakatsuka, Y., Sugai, T. & Ohta, H., 1996 1月, In: Bioscience, Biotechnology and Biochemistry. 60, 9, p. 1540-1542 3 p.研究成果: Article › 査読
Open Access7 被引用数 (Scopus) -
Biocatalytic approaches to both enantiomers of (2R*,3S*)-2-allyloxy-3,4,5,6-tetrahydro-2H-pyran-3-ol
Sugai, T., Ikeda, H. & Ohta, H., 1996 6月 10, In: Tetrahedron. 52, 24, p. 8123-8134 12 p.研究成果: Article › 査読
11 被引用数 (Scopus) -
Biocatalytic preparation of (R)-(-)-4-(phenylthio)-2-butanol and (R)-(-)-4-(Phenylsulfonyl)-2-butanol by the sequential use of Pichia farinosa and Rhodococcus rhodochrous
Sugai, T., Ohtsuka, Y. & Ohta, H., 1996 1月 1, In: Chemistry Letters. 3, p. 233-234 2 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
Efficient Lipase-catalyzed Preparation of Long-chain Fatty Acid Esters of Bile Acids: Biological Activity and Synthetic Application of the Products
Sugai, T., Takizawa, M., Bakke, M., Ohtsuka, Y. & Oht, H., 1996 1月, In: Bioscience, Biotechnology and Biochemistry. 60, 12, p. 2059-2063 5 p.研究成果: Article › 査読
Open Access23 被引用数 (Scopus) -
Exchanges of polar amino acids to alanine generate platelet-activating factor receptor mutants with altered affinities to their ligand
Ishii, I., Izuro, T., Ui, M. & Shimizii, T., 1996, In: FASEB Journal. 10, 6, p. A1099研究成果: Article › 査読
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Glutathione isopropyl ester reduces UVB-induced skin damage in hairless mice
Kobayashi, S., Takehana, M. & Tohyama, C., 1996 1月 1, In: Photochemistry and Photobiology. 63, 1, p. 106-110 5 p.研究成果: Article › 査読
25 被引用数 (Scopus) -
Morphological study of age-related changes in Fischer rat lens
Uga, S., Obara, Y., Takehana, M., Nishigori, H., Hikida, M. & Mibu, H., 1996 5月 14, In: Japanese Journal of Ophthalmology. 40, 1, p. 33-41 9 p.研究成果: Article › 査読
3 被引用数 (Scopus) -
Preparation of both enantiomers of methyl 3-benzoyloxypentanoate by enzyme-catalysed hydrolysis of corresponding racemic nitrile and amide
Yokoyama, M., Imai, N., Sugai, T. & Ohta, H., 1996 6月, In: Journal of Molecular Catalysis B: Enzymatic. 1, 3-6, p. 135-141 7 p.研究成果: Article › 査読
26 被引用数 (Scopus) -
Temperature-responsive chromatography using poly(N-isopropylacrylamide)-modified silica
Kanazawa, H., Yamamoto, K., Matsushima, Y., Takai, N., Kikuchi, A., Sakurai, Y. & Okano, T., 1996 12月 1, In: Analytical chemistry. 68, 1, p. 100-105 6 p.研究成果: Article › 査読
408 被引用数 (Scopus) -
Yeast-mediated synthesis of optically active diols with C2-symmetry and (R)-4-pentanolide
Ikeda, H., Sato, E., Sugai, T. & Ohta, H., 1996 6月 10, In: Tetrahedron. 52, 24, p. 8113-8122 10 p.研究成果: Article › 査読
49 被引用数 (Scopus) -
1997
A Chemo-Enzymatic Synthesis of D-Allosamine Derivatives from Tri-O-acetyl- D-glucal
Sugai, T., Okazaki, H., Kuboki, A. & Ohta, H., 1997 10月, In: Bulletin of the Chemical Society of Japan. 70, 10, p. 2535-2540 6 p.研究成果: Article › 査読
14 被引用数 (Scopus) -
Alanine exchanges of polar amino acids in the transmembrane domains of a platelet-activating factor receptor generate both constitutively active and inactive mutants
Ishii, I., Izumi, T., Tsukamoto, H., Umeyama, H., Ui, M. & Shimizuf, T., 1997, In: Journal of Biological Chemistry. 272, 12, p. 7846-7854 9 p.研究成果: Article › 査読
55 被引用数 (Scopus) -
Analysis of peptides and proteins by temperature-responsive chromatographic system using N-isopropylacrylamide polymer-modified columns
Kanazawa, H., Yamamoto, K., Kashiwase, Y., Matsushima, Y., Takai, N., Kikuchi, A., Sakurai, Y. & Okano, T., 1997 6月, In: Journal of Pharmaceutical and Biomedical Analysis. 15, 9-10, p. 1545-1550 6 p.研究成果: Article › 査読
80 被引用数 (Scopus) -
An expeditious route to N-glycolylneuraminic acid based on enzyme-catalyzed reaction
Kuboki, A., Okazaki, H., Sugai, T. & Ohta, H., 1997 2月 17, In: Tetrahedron. 53, 7, p. 2387-2400 14 p.研究成果: Article › 査読
40 被引用数 (Scopus) -
Biocatalysis in Organic Synthesis: The Use of Nitrile- and Amide-hydrolyzing Microorganisms
Sugai, T., Yamazaki, T., Yokoyama, M. & Ohta, H., 1997 1月, In: Bioscience, Biotechnology and Biochemistry. 61, 9, p. 1419-1427 9 p.研究成果: Article › 査読
131 被引用数 (Scopus) -
Biocatalyst-Mediated Efficient Preparation of Highly Enantiomerically Enriched (R)-5-Hexanolide
Sugai, T., Hamada, K., Akeboshi, T., Ikeda, H. & Ohta, H., 1997 1月 1, In: Synlett. 1997, 8, p. 983-985 3 p.研究成果: Article › 査読
17 被引用数 (Scopus) -
Brewers' yeast-mediated synthesis of (1S,2S)-1-(2-thienyl)-1,2-propanediol and a study on the lipase-catalyzed regioselective introduction of acyl protective group to the diol moiety
Mochizuki, N., Sugai, T., Ohta, H., Yokomatsu, T. & Shibuya, S., 1997 12月 1, In: Heterocycles. 45, 2, p. 331-338 8 p.研究成果: Article › 査読
1 被引用数 (Scopus)