年別の研究成果
年別の研究成果
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Examination of spacer effects on stereochemical recognition of a remote sterically hindered chiral center in lipase-catalyzed acylation
Kobayashi, R., Huang, H., Hamada, M., Higashi, T., Shoji, M. & Sugai, T., 2012 9月, In: Journal of Molecular Catalysis B: Enzymatic. 81, p. 52-57 6 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Epithelium-intrinsic MicroRNAs contribute to mucosal immune homeostasis by promoting M-cell maturation
Nakato, G., Hase, K., Sato, T., Kimura, S., Sakakibara, S., Sugiyama, M., Obata, Y., Hanazato, M., Iwanaga, T. & Ohno, H., 2016 3月, In: PloS one. 11, 3, e0150379.研究成果: Article › 査読
Open Access11 被引用数 (Scopus) -
Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues
Obata, Y., Kimura, S., Nakato, G., Iizuka, K., Miyagawa, Y., Nakamura, Y., Furusawa, Y., Sugiyama, M., Suzuki, K., Ebisawa, M., Fujimura, Y., Yoshida, H., Iwanaga, T., Hase, K. & Ohno, H., 2014 12月 1, In: EMBO Reports. 15, 12, p. 1297-1304 8 p.研究成果: Article › 査読
Open Access10 被引用数 (Scopus) -
Enzyme-mediated optical resolution of 2-methyl-3,4-pentadien-1-ol, a chiral building block possessing terminal allenyl group
Konegawa, T., Ohtsuka, Y., Ikeda, H., Sugai, T. & Ohta, H., 1997, In: Synlett. 1997, 11, p. 1297-1299 3 p.研究成果: Article › 査読
13 被引用数 (Scopus) -
Enzyme-catalyzed resolution of 3,8-dioxatricyclo[3.2.1.02,4]octane-6-carboxylic esters and the application to the synthesis of 3-epishikimic acid
Hamada, M., Inami, Y., Nagai, Y., Higashi, T., Shoji, M., Ogawa, S., Umezawa, K. & Sugai, T., 2009 9月 23, In: Tetrahedron Asymmetry. 20, 18, p. 2105-2111 7 p.研究成果: Article › 査読
8 被引用数 (Scopus) -
Enzyme-catalyzed enantiomeric resolution of N-Boc-proline as the key-step in an expeditious route towards RAMP
Kurokawa, M., Shindo, T., Suzuki, M., Nakajima, N., Ishihara, K. & Sugai, T., 2003 5月 16, In: Tetrahedron Asymmetry. 14, 10, p. 1323-1333 11 p.研究成果: Article › 査読
22 被引用数 (Scopus) -
Enzyme- and microorganism-mediated syntheses of substances related to glycoconjugates
Kuboki, A., Bakke, M., Sekiguchi, T., Ohta, H. & Sugai, T., 1998 6月, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 56, 6, p. 489-499 11 p.研究成果: Article › 査読
Open Access1 被引用数 (Scopus) -
Enzymatic Preparation of Ethyl (S)-3-Hydroxybutanoate with a High Enantiomeric Excess
Sugai, T. & Ohta, H., 1989, In: Agricultural and biological chemistry. 53, 7, p. 2009-2010 2 p.研究成果: Article › 査読
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Enzymatic preparation of ethyl (5)- 3-hydroxybutanoate with a high enantiomeric excess
Sugai, T. & Ohta, H., 1989 7月, In: Agricultural and biological chemistry. 53, 7, p. 2009-2010 2 p.研究成果: Article › 査読
30 被引用数 (Scopus) -
Enzymatic Preparation of Enantiomerically Enriched Tertiary a-Benzyloxy Acid Esters. Application to the Synthesis of (S)-(-)-Frontalin
Sugai, T., Kakeya, H. & Ohta, H., 1990 1月 1, In: Journal of Organic Chemistry. 55, 15, p. 4643-4647 5 p.研究成果: Article › 査読
64 被引用数 (Scopus) -
Enzymatic kinetic resolution of cyanohydrin acetates and its application to the synthesis of (S)-(-)-frontalin
Ohta, H., Kimura, Y., Sugano, Y. & Sugai, T., 1989, In: Tetrahedron. 45, 17, p. 5469-5476 8 p.研究成果: Article › 査読
60 被引用数 (Scopus) -
Environmental behavior on the lens opacification (Japanese)
Iwata, S., Ikemoto, F. & Takehana, M., 1976 12月 1, In: Journal of Japanese Ophthalmological Society. 80, 9, p. 741-748 8 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Enhanced serum antigen-specific IgG1 and proinflammatory cytokine production in nicotinic acetylcholine receptor α7 subunit gene knockout mice
Fujii, Y. X., Fujigaya, H., Moriwaki, Y., Misawa, H., Kasahara, T., Grando, S. A. & Kawashima, K., 2007 9月, In: Journal of Neuroimmunology. 189, 1-2, p. 69-74 6 p.研究成果: Article › 査読
75 被引用数 (Scopus) -
Enhanced mechanical properties and cell separation with thermal control of PIPAAm-brushed polymer-blend microfibers
Nagase, K., Shukuwa, R., Takahashi, H., Takeda, N. & Okano, T., 2020 7月 28, In: Journal of Materials Chemistry B. 8, 28, p. 6017-6026 10 p.研究成果: Article › 査読
16 被引用数 (Scopus) -
Enhanced cellular uptake and gene silencing activity of siRNA using temperature-responsive polymer-modified liposome
Wang, J., Ayano, E., Maitani, Y. & Kanazawa, H., 2017 5月 15, In: International Journal of Pharmaceutics. 523, 1, p. 217-228 12 p.研究成果: Article › 査読
30 被引用数 (Scopus) -
Engineered Human Muscle Tissue from Multilayered Aligned Myofiber Sheets for Studies of Muscle Physiology and Predicting Drug Response
Takahashi, H., Wakayama, H., Nagase, K. & Shimizu, T., 2022, (Accepted/In press) In: Small Methods.研究成果: Article › 査読
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Endogenous neurotoxin-like protein Ly6H inhibits alpha7 nicotinic acetylcholine receptor currents at the plasma membrane
Moriwaki, Y., Kubo, N., Watanabe, M., Asano, S., Shinoda, T., Sugino, T., Ichikawa, D., Tsuji, S., Kato, F. & Misawa, H., 2020 12月 1, In: Scientific reports. 10, 1, 11996.研究成果: Article › 査読
Open Access6 被引用数 (Scopus) -
Endogenous hydrogen sulfide protects pancreatic beta-cells from a high-fat diet-induced glucotoxicity and prevents the development of type 2 diabetes
Okamoto, M., Yamaoka, M., Takei, M., Ando, T., Taniguchi, S., Ishii, I., Tohya, K., Ishizaki, T., Niki, I. & Kimura, T., 2013 12月 13, In: Biochemical and Biophysical Research Communications. 442, 3-4, p. 227-233 7 p.研究成果: Article › 査読
40 被引用数 (Scopus) -
Enantioselective synthesis of the medium ring ethers, tetrahydrooxepin, oxocane and hexahydrooxonin, of ciguatoxin. Extensive ring-expansion and chemoenzymatic desymmetrization strategy
Oishi, T., Maruyama, M., Shoji, M., Maeda, K., Kumahara, N., Tanaka, S. I. & Hirama, M., 1999 6月 11, In: Tetrahedron. 55, 24, p. 7471-7498 28 p.研究成果: Article › 査読
39 被引用数 (Scopus) -
Enantioselective synthesis of heliannuol E; structural consideration of natural molecule
Doi, F., Ogamino, T., Sugai, T. & Nishiyama, S., 2003 6月 23, In: Tetrahedron Letters. 44, 26, p. 4877-4880 4 p.研究成果: Article › 査読
45 被引用数 (Scopus) -
Enantiomeric determination of L- and D-lactic acid in human cerebrospinal fluid by chiral ligand exchange high-performance liquid chromatography
Okubo, S., Mashige, F., Omori, M., Hashimoto, Y., Nakahara, K., Kanazawa, H. & Matsushima, Y., 2000 11月 29, In: Biomedical Chromatography. 14, 7, p. 474-477 4 p.研究成果: Article › 査読
24 被引用数 (Scopus) -
Enantiomerically Pure Octahydronaphthalenone and Octahydroindenone: Elaboration of the Substrate Overcame the Specificity of Yeast-Mediated Reduction
Fuhshuku, K. I., Tomita, M. & Sugai, T., 2003 6月, In: Advanced Synthesis and Catalysis. 345, 6-7, p. 766-774 9 p.研究成果: Article › 査読
27 被引用数 (Scopus) -
Enantio- and diastereoselective total synthesis of EI-1941-1, -2, and -3, inhibitors of interleukin-1β converting enzyme, and biological properties of their derivatives
Shoji, M., Uno, T., Kakeya, H., Onose, R., Shiina, I., Osada, H. & Hayashi, Y., 2005 11月 25, In: Journal of Organic Chemistry. 70, 24, p. 9905-9915 11 p.研究成果: Article › 査読
27 被引用数 (Scopus) -
Elastin expression in cultured human keratinocytes: Exon 26A of elastin primary transcript is always included in terminally differentiated keratinocytes
Hirano, E., Okamoto, K., Matsubara, Y., Takehana, M., Kobayashi, S. & Tajima, S., 2001 10月 17, In: Archives of Dermatological Research. 293, 8, p. 430-433 4 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
Elaboration on the access to (S)-4-(4-methylbenzyl)oxy-3-hydroxybutanenitrile, a key intermediate for statins, by combining the kinetic resolution of racemate and the recycle of undesired enantiomer
Sakamoto, M., Hamada, M., Higashi, T., Shoji, M. & Sugai, T., 2010 6月, In: Journal of Molecular Catalysis B: Enzymatic. 64, 1-2, p. 96-100 5 p.研究成果: Article › 査読
6 被引用数 (Scopus) -
Efficient route to (S)-azetidine-2-carboxylic acid
Futamura, Y., Kurokawa, M., Obata, R., Nishiyama, S. & Sugai, T., 2005 10月 23, In: Bioscience, Biotechnology and Biochemistry. 69, 10, p. 1892-1897 6 p.研究成果: Article › 査読
22 被引用数 (Scopus) -
Efficient Lipase-catalyzed Preparation of Long-chain Fatty Acid Esters of Bile Acids: Biological Activity and Synthetic Application of the Products
Sugai, T., Takizawa, M., Bakke, M., Ohtsuka, Y. & Oht, H., 1996 1月, In: Bioscience, Biotechnology and Biochemistry. 60, 12, p. 2059-2063 5 p.研究成果: Article › 査読
Open Access23 被引用数 (Scopus) -
Efficient entrapment of poorly water-soluble pharmaceuticals in hybrid nanoparticles
Ishihara, T., Goto, M., Kanazawa, H., Higaki, M. & Mizushima, Y., 2009 7月, In: Journal of Pharmaceutical Sciences. 98, 7, p. 2357-2363 7 p.研究成果: Article › 査読
20 被引用数 (Scopus) -
Effects of terminal group and chain length on temperature-responsive chromatography utilizing poly(N-isopropylacrylamide) synthesized via RAFT polymerization
Hiruta, Y., Nagumo, Y., Miki, A., Okano, T. & Kanazawa, H., 2015 8月 24, In: RSC Advances. 5, 89, p. 73217-73224 8 p.研究成果: Article › 査読
15 被引用数 (Scopus) -
Effects of graft densities and chain lengths on separation of bioactive compounds by nanolayered thermoresponsive Polymer brush surfaces
Nagase, K., Kobayashi, J., Kikuchi, A., Akiyama, Y., Kanazawa, H. & Okano, T., 2008 1月 15, In: Langmuir. 24, 2, p. 511-517 7 p.研究成果: Article › 査読
150 被引用数 (Scopus) -
Effects of a water-soluble prodrug of vitamin E on doxorubicin-induced toxicity in mice
Nagata, Y., Takata, J., Yoshiharu Karube, A. & Matsushima, Y., 1999 7月, In: Biological and Pharmaceutical Bulletin. 22, 7, p. 698-702 5 p.研究成果: Article › 査読
Open Access11 被引用数 (Scopus) -
Effect of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1) on airway epithelial cells
Narumoto, O., Niikura, Y., Ishii, S., Morihara, H., Okashiro, S., Nakahari, T., Nakano, T., Matsumura, H., Shimamoto, C., Moriwaki, Y., Misawa, H., Yamashita, N., Nagase, T., Kawashima, K. & Yamashita, N., 2013 8月 16, In: Biochemical and Biophysical Research Communications. 438, 1, p. 175-179 5 p.研究成果: Article › 査読
16 被引用数 (Scopus) -
Effect of reaction solvent on the preparation of thermo-responsive stationary phase through a surface initiated atom transfer radical polymerization
Nagase, K., Mizutani Akimoto, A., Kobayashi, J., Kikuchi, A., Akiyama, Y., Kanazawa, H. & Okano, T., 2011 12月 2, In: Journal of Chromatography A. 1218, 48, p. 8617-8628 12 p.研究成果: Article › 査読
41 被引用数 (Scopus) -
Effect of pore diameter on the elution behavior of analytes from thermoresponsive polymer grafted beads packed columns
Nagase, K., Umemoto, Y. & Kanazawa, H., 2021 12月, In: Scientific reports. 11, 1, 9976.研究成果: Article › 査読
Open Access11 被引用数 (Scopus) -
Effect of polyvinyl butyrate nanoparticles incorporated with immune suppressing vitamins on alteration of population of intestinal immune cells
Mu, Y., Kinashi, Y., Kishimura, A., Mori, T., Hase, K. & Katayama, Y., 2020 10月, In: Progress in Natural Science: Materials International. 30, 5, p. 707-710 4 p.研究成果: Article › 査読
Open Access2 被引用数 (Scopus) -
Effect of polymer phase transition behavior on temperature-responsive polymer-modified liposomes for siRNA transfection
Nagase, K., Hasegawa, M., Ayano, E., Maitani, Y. & Kanazawa, H., 2019 1月 2, In: International journal of molecular sciences. 20, 2, 430.研究成果: Article › 査読
Open Access33 被引用数 (Scopus) -
Effect of metabolic inhibition against CYP3A4 by catechins in bottled green tea drinks
Nakamura, T., Asada, E., Nagata, Y. & Kanazawa, H., 2003 9月, In: BUNSEKI KAGAKU. 52, 9, p. 769-773 5 p.研究成果: Article › 査読
2 被引用数 (Scopus) -
Effect of hesperetin on chaperone activity in selenite-induced cataract
Nakazawa, Y., Oka, M., Tamura, H. & Takehana, M., 2016 6月 1, In: Open Medicine (Poland). 11, 1, p. 183-189 7 p.研究成果: Article › 査読
12 被引用数 (Scopus) -
Effect of hesperetin derivatives on the development of selenite-induced cataracts in rats
Nakazawa, Y., Pauze, M., Fukuyama, K., Nagai, N., Funakoshi-Tago, M., Sugai, T. & Tamura, H., 2018 7月, In: Molecular Medicine Reports. 18, 1, p. 1043-1050 8 p.研究成果: Article › 査読
Open Access10 被引用数 (Scopus) -
Effect of chemical modification on the ability of pyrrolidinium fullerene to induce apoptosis of cells transformed by JAK2 V617F mutant
Funakoshi-Tago, M., Tsukada, M., Watanabe, T., Mameda, Y., Tago, K., Ohe, T., Nakamura, S., Mashino, T. & Kasahara, T., 2014 5月, In: International Immunopharmacology. 20, 1, p. 258-263 6 p.研究成果: Article › 査読
9 被引用数 (Scopus) -
Effective Separation for New Therapeutic Modalities Utilizing Temperature-responsive Chromatography
Maekawa, Y., Ayano, E., Nagase, K. & Kanazawa, H., 2021 5月, In: analytical sciences. 37, 5, p. 651-660 10 p.研究成果: Article › 査読
Open Access6 被引用数 (Scopus) -
EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity
Li, Y., Takahashi, Y., Fujii, S. I., Zhou, Y., Hong, R., Suzuki, A., Tsubata, T., Hase, K. & Wang, J. Y., 2016 3月 3, In: Nature communications. 7, 10836.研究成果: Article › 査読
Open Access20 被引用数 (Scopus) -
Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses
Toyama, Y., Kano, H., Mase, Y., Yokogawa, M., Osawa, M. & Shimada, I., 2017 2月 22, In: Nature communications. 8, 14523.研究成果: Article › 査読
Open Access27 被引用数 (Scopus) -
Dual temperature-and pH-responsive polymeric micelle for selective and efficient two-step doxorubicin delivery
Hiruta, Y., Kanda, Y., Katsuyama, N. & Kanazawa, H., 2017, In: RSC Advances. 7, 47, p. 29540-29549 10 p.研究成果: Article › 査読
23 被引用数 (Scopus) -
D-Tryptophan suppresses enteric pathogen and pathobionts and prevents colitis by modulating microbial tryptophan metabolism
Seki, N., Kimizuka, T., Gondo, M., Yamaguchi, G., Sugiura, Y., Akiyama, M., Yakabe, K., Uchiyama, J., Higashi, S., Haneda, T., Suematsu, M., Hase, K. & Kim, Y., 2022 8月 19, In: iScience. 25, 8, 104838.研究成果: Article › 査読
Open Access -
Dry and wet prolines for asymmetric organic solvent-free aldehyde-aldehyde and aldehyde-ketone aldol reactions
Hayashi, Y., Aratake, S., Itoh, T., Okano, T., Sumiya, T. & Shoji, M., 2007, In: Chemical Communications. 9, p. 957-959 3 p.研究成果: Article › 査読
121 被引用数 (Scopus) -
Drug repositioning for preeclampsia therapeutics by in vitro screening
Kakigano, A., Tomimatsu, T., Mimura, K., Kanayama, T., Fujita, S., Minato, K., Kumasawa, K., Taniguchi, Y., Kanagawa, T., Endo, M., Ishihara, T., Namba, T., Mizushima, T. & Kimura, T., 2015 10月 22, In: Reproductive Sciences. 22, 10, p. 1272-1280 9 p.研究成果: Article › 査読
13 被引用数 (Scopus) -
Down-regulation of secreted lymphocyte antigen-6/urokinase-type plasminogen activator receptor-related peptide-1 (SLURP-1), an endogenous allosteric α7 nicotinic acetylcholine receptor modulator, in murine and human asthmatic conditions
Narumoto, O., Horiguchi, K., Horiguchi, S., Moriwaki, Y., Takano-Ohmuro, H., Shoji, S., Misawa, H., Yamashita, N., Nagase, T., Kawashima, K. & Yamashita, N., 2010 8月, In: Biochemical and Biophysical Research Communications. 398, 4, p. 713-718 6 p.研究成果: Article › 査読
18 被引用数 (Scopus) -
Divergent synthesis of pseudoenantiomers for ABC-ring moiety of steroids
Furuta, M., Hanaya, K., Sugai, T. & Shoji, M., 2014 5月 14, In: Tetrahedron Letters. 55, 20, p. 3189-3191 3 p.研究成果: Article › 査読
1 被引用数 (Scopus) -
Disulfide mapping the voltage-sensing mechanism of a voltage-dependent potassium channel
Nozaki, T., Ozawa, S. I., Harada, H., Kimura, T., Osawa, M. & Shimada, I., 2016 11月 17, In: Scientific reports. 6, 37303.研究成果: Article › 査読
Open Access1 被引用数 (Scopus)