薬科学科

研究成果

年別の研究成果 1976 2012 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

• 716 Article
• 41 Review article
• 11 Chapter
• 7 Paper
• 20 その他
  • 7 Comment/debate
  • 5 Conference contribution
  • 5 Letter
  • 2 Editorial
  • 1 Short survey

年別の研究成果

年別の研究成果

検索結果

• Article

  Synthesis and property of three-dimensional curved heterocyclic π-electron molecules with embedded nitrogen atoms

  Higashibayashi, S., 2019, In: Yuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry. 77, 12, p. 1209-1221 13 p.

  研究成果: Article › 査読

  • Nitrogen Atom 100%
  • Molecule 41%
  • Carbazole 36%
  • Disproportionation 34%
  • Reductive Desulfurization 27%
  2 被引用数 (Scopus)

• Synthesis of (Rc,Ss)-1,1,1-trifluoro-3-(p-molylsulfinyl)-2-propanol by an asymmetric reduction with a yeast, Yamadazyma farinosa, as a key-step

  Sakai, A., Bakke, M., Ohta, H., Kosugi, H. & Sugai, T., 1999, In: Chemistry Letters. 11, p. 1255-1256 2 p.

  研究成果: Article › 査読

  • Sulfoxide 100%
  • Sulfur Atom 98%
  • Stereoselectivity 94%
  • Reduction 91%
  • Carbonyl Group 89%
  7 被引用数 (Scopus)

• Synthesis of 1H-2-Benzopyran-5,8-dione Skeleton through a Cascade Reaction between Benzoquinone and β-Ketoester

  Nakahara, M., Ohtsu, H., Kawano, M., Hanaya, K., Sugai, T. & Higashibayashi, S., 2022 4月, In: Chemistry Letters. 51, 4, p. 356-359 4 p.

  研究成果: Article › 査読

  • Benzoquinone 100%
  • Potassium Carbonate 99%
  • 18-Crown-6 96%
  • Michael Addition 87%
  • Alkaline Condition 81%

• Synthesis of 3β-tert-Butyldimethylsiloxy-22-phenylthio-23,24-bisnorchola-5,9(11)-diene and Reductive Nucleophilic Attack on a Branched Aliphatic Aldehyde

  Nagai, T., Hanaya, K., Higashibayashi, S., Shoji, M. & Sugai, T., 2018, In: Chemical and Pharmaceutical Bulletin. 66, 3, p. 334-338 5 p.

  研究成果: Article › 査読

  Open Access

  • Aldehydes 100%
  • Aliphatic Aldehyde 99%
  • Lewis Acids 80%
  • Steroid 76%
  • compound 17 68%

• Synthesis of 5-Hydroxy-3′,4′,7-trimethoxyflavone and Related Compounds and Elucidation of Their Reversal Effects on BCRP/ABCG2-Mediated Anticancer Drug Resistance

  Tsunekawa, R., Katayama, K., Hanaya, K., Higashibayashi, S., Sugimoto, Y. & Sugai, T., 2019 1月 18, In: ChemBioChem. 20, 2, p. 210-220 11 p.

  研究成果: Article › 査読

  • 5-hydroxy-3',4',6,7-tetramethoxyflavone 100%
  • Protein Binding 73%
  • Drug Resistance 67%
  • Adenosine Triphosphate 57%
  • Trimethoxyflavone 54%
  1 被引用数 (Scopus)

• Synthesis of a C₇₀ Fragment Buckybowl C₂₈H₁₄ from a C₆₀ fragment sumanene

  Hishikawa, S., Okabe, Y., Tsuruoka, R., Higashibayashi, S., Ohtsu, H., Kawano, M., Yakiyama, Y. & Sakurai, H., 2017, In: Chemistry Letters. 46, 10, p. 1556-1559 4 p.

  研究成果: Article › 査読

  • Inversion Barrier 100%
  • Ring Expansion 78%
  • Ring Formation 71%
  14 被引用数 (Scopus)

• Synthesis of acacetin and resveratrol 3,5-di-O-β-glucopyranoside using lipase-catalyzed regioselective deacetylation of polyphenol glycoside peracetates as the key step

  Hanamura, S., Hanaya, K., Shoji, M. & Sugai, T., 2016 6月 1, In: Journal of Molecular Catalysis B: Enzymatic. 128, p. 19-26 8 p.

  研究成果: Article › 査読

  • Novozyme 435 100%
  • Resveratrol 93%
  • Candida antarctica lipase B 90%
  • Glycosides 86%
  • acacetin 82%
  15 被引用数 (Scopus)

• Synthesis of benzyl tetra-O-acetyl-α-L-glucopyranoside from benzyl 2,3-dideoxy-β-D-Erythro-hex-2-enopyranoside

  Okazaki, H., Ueda, Y., Hanaya, K., Shoji, M. & Sugai, T., 2017, In: Heterocycles. 95, 2, p. 862-871 10 p.

  研究成果: Article › 査読

  • benzyl glucopyranoside 100%
  • D-Glucose 51%
  • Glucose 28%
  • L-Glucose 23%
  • Epimerization 17%
  1 被引用数 (Scopus)

• Synthesis of bioactive sesquiterpene heliannuol E involving a ring-expansion reaction of spirodienones

  Doi, F., Ogamino, T., Sugai, T. & Nishiyama, S., 2003, In: Synlett. 3, p. 411-413 3 p.

  研究成果: Article › 査読

  • Spiro Compound 100%
  • Ring Expansion 81%
  • Sesquiterpene 77%
  31 被引用数 (Scopus)

• Synthesis of citronellyl acetate via a transacetylation to citronellol from acetyl coenzyme A produced from glucose and acetate in growing yeasts

  Oda, S., Sugai, T. & Ohta, H., 2001, In: Chemistry Letters. 6, p. 500-501 2 p.

  研究成果: Article › 査読

  • Citronellol 100%
  • Coenzyme A 83%
  • Acetylation 68%
  • Acetyl 67%
  • Glucose 50%
  1 被引用数 (Scopus)

• Synthesis of enantiomerically enriched drug precursors and an insect pheromone via reduction of ketones using commercially available carbonyl reductase screening kit “Chiralscreen® OH”

  Nagai, T., Sakurai, S., Natori, N., Hataoka, M., Kinoshita, T., Inoue, H., Hanaya, K., Shoji, M. & Sugai, T., 2018 4月 1, In: Bioorganic and Medicinal Chemistry. 26, 7, p. 1304-1313 10 p.

  研究成果: Article › 査読

  • Alcohol Oxidoreductases 100%
  • Pheromones 80%
  • Ketones 75%
  • Pheromone 75%
  • (R)-Chlorphenesin 69%
  12 被引用数 (Scopus)

• Synthesis of enantiomers of indanoxazolidinone based on the lipase-catalyzed resolution of the corresponding N-carbamylamino derivative

  Suzuki, M., Nagasawa, C. & Sugai, T., 2001 6月 4, In: Tetrahedron. 57, 23, p. 4841-4848 8 p.

  研究成果: Article › 査読

  • 2-indanol 100%
  • Oxazolidinone 52%
  • Lipase 45%
  • Quantitative Yield 43%
  • aminoindanol 34%
  14 被引用数 (Scopus)

• Synthesis of fisetin and 2′,4′,6′-trihydroxydihyrochalcone 4′-O-β-neohesperidoside based on site-selective deacetylation and deoxygenation

  Tsunekawa, R., Hanaya, K., Higashibayashi, S. & Sugai, T., 2018, In: Bioscience, Biotechnology and Biochemistry. 82, 8, p. 1316-1322 7 p.

  研究成果: Article › 査読

  Open Access

  • fisetin 100%
  • Fisetin 96%
  • naringin 95%
  • Naringin 88%
  • Deacetylation 72%
  7 被引用数 (Scopus)

• Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity

  Yasuda, D., Nakajima, M., Yuasa, A., Obata, R., Takahashi, K., Ohe, T., Ichimura, Y., Komatsu, M., Yamamoto, M., Imamura, R., Kojima, H., Okabe, T., Nagano, T. & Mashino, T., 2016, In: Bioorganic and Medicinal Chemistry Letters. 26, 24, p. 5956-5959 4 p.

  研究成果: Article › 査読

  • P62 100%
  • Naphthalene 54%
  • naphthalene 42%
  • Sequestosome-1 Protein 27%
  • Proteins 22%
  34 被引用数 (Scopus)

• Synthesis of linezolid metabolites PNU-142300 and PNU-142586 toward the exploration of metabolite-related events

  Hanaya, K., Matsumoto, K., Yokoyama, Y., Kizu, J., Shoji, M. & Sugai, T., 2017, In: Chemical and Pharmaceutical Bulletin. 65, 2, p. 194-199 6 p.

  研究成果: Article › 査読

  • PNU-142586 100%
  • PNU-142300 98%
  • Linezolid 64%
  • Metabolite 29%
  • morpholine 23%
  1 被引用数 (Scopus)

• Synthesis of methyl epi-anhydroquinate utilizing [2,3]-sigmatropic rearrangement of iodosoalkene

  Inomata, S., Ueda, M., Sugai, T. & Shoji, M., 2013, In: Chemistry Letters. 42, 10, p. 1273-1275 3 p.

  研究成果: Article › 査読

  • Quinic Acid 100%
  • Epimer 81%
  • Stereoselectivity 64%
  • Occurrence in Nature 57%
  • Block Like Crystal 46%
  1 被引用数 (Scopus)

• Synthesis of methyl ursodeoxycholate via microbial reduction of methyl 7-ketolithocholate with Eubacterium aerofaciens JCM 7790 grown on two kinds of carbon and hydride sources, glucose and mannitol

  Oda, S., Sugai, T. & Ohta, H., 2001 1月 1, In: Journal of Bioscience and Bioengineering. 91, 2, p. 178-183 6 p.

  研究成果: Article › 査読

  • Ursodeoxycholate 100%
  • Oxidoreductases 85%
  • Eubacterium 84%
  • Hydroxysteroid Dehydrogenases 77%
  • Hydrides 70%
  11 被引用数 (Scopus)

• Synthesis of novel benzbromarone derivatives designed to avoid metabolic activation

  Ohe, T., Umezawa, R., Kitagawara, Y., Yasuda, D., Takahashi, K., Nakamura, S., Abe, A., Sekine, S., Ito, K., Okunushi, K., Morio, H., Furihata, T., Anzai, N. & Mashino, T., 2018 12月 15, In: Bioorganic and Medicinal Chemistry Letters. 28, 23-24, p. 3708-3711 4 p.

  研究成果: Article › 査読

  • Benzbromarone 100%
  • Metabolic Activation 69%
  • Uricosuric Agent 53%
  • Uricosuric Agents 48%
  • Uric Acid 29%
  7 被引用数 (Scopus)

• Synthesis of okicamelliaside, a glucoside of ellagic acid with potent anti-degranulation activity

  Kobayashi, R., Hanaya, K., Shoji, M., Ohba, S. & Sugai, T., 2013, In: Bioscience, Biotechnology and Biochemistry. 77, 4, p. 810-813 4 p.

  研究成果: Article › 査読

  • okicamelliaside 100%
  • Ellagic Acid 58%
  • Glucosides 53%
  • Glucoside 46%
  • Skeleton 20%
  3 被引用数 (Scopus)

• Synthesis of oroxylin A starting from naturally abundant baicalin

  Fujita, R., Hanaya, K., Higashibayashi, S. & Sugai, T., 2018, In: Heterocycles. 97, 2, p. 1165-1174 10 p.

  研究成果: Article › 査読

  • Oroxylin A 100%
  • 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one 98%
  • Baicalin 81%
  • baicalin 80%
  • Acetyl Group 42%
  6 被引用数 (Scopus)

• Synthesis of Regioselectively Protected Forms of Cytidine Based on Enzyme-catalyzed Deacetylation as the Key Step

  Kuboki, A., Ishihara, T., Kobayashi, E., Ohta, H., Ishii, T., Inoue, A., Mitsuda, S., Miyazaki, T., Kajihara, Y. & Sugai, T., 2000 1月 1, In: Bioscience, Biotechnology and Biochemistry. 64, 2, p. 363-368 6 p.

  研究成果: Article › 査読

  • Cytidine 100%
  • Esterases 86%
  • Phosphoramidite 86%
  • Deacetylation 84%
  • N-acetylcytidine 74%
  5 被引用数 (Scopus)

• Synthesis of Sulfinimines by Direct Condensation of Sulfinamides with Aldehydes Using Cs₂CO₃ as an Activating and Dehydrating Reagent

  Higashibayashi, S., Tohmiya, H., Mori, T., Hashimoto, K. & Nakata, M., 2004 2月 18, In: Synlett. 3, p. 457-460 4 p.

  研究成果: Article › 査読

  • Carbonate 100%
  • Condensation 92%
  • Aldehyde 88%
  39 被引用数 (Scopus)

• Synthesis of the (4R,5R)-Isomer of 5-Hydroxy-6-phenyl-4-hexanolide, a Lateral Root-inducing Substance Isolated from Erwinia quercina

  Sugai, T., Noguchi, H. & Ohta, H., 1992 1月 1, In: Bioscience, Biotechnology, and Biochemistry. 56, 1, p. 122-126 5 p.

  研究成果: Article › 査読

  • Erwinia 100%
  • Lactones 77%
  • Lipase 66%
  • Hydrogenolysis 63%
  • Enzymatic Reaction 60%
  7 被引用数 (Scopus)

• Synthesis of the 1,2-seco fusicoccane diterpene skeleton by Stille coupling reaction between the highly functionalized A and C ring segments of cotylenin A

  Kuwata, K., Hanaya, K., Higashibayashi, S., Sugai, T. & Shoji, M., 2017, In: Tetrahedron. 73, 41, p. 6039-6045 7 p.

  研究成果: Article › 査読

  • cotylenin A 100%
  • cyclopentanone 89%
  • Stille Coupling Reaction 68%
  • Diterpenes 63%
  • Diterpene 54%
  8 被引用数 (Scopus)

• Synthesis of trans,trans,cis-fused tetracyclic skeleton via radical domino cyclization

  Furuta, M., Hanaya, K., Sugai, T. & Shoji, M., 2017, In: Tetrahedron. 73, 16, p. 2316-2322 7 p.

  研究成果: Article › 査読

  • Limonins 100%
  • Cyclization 86%
  • Limonoid 84%
  • Skeleton 58%
  • Cyclization Reaction 42%
  7 被引用数 (Scopus)

• Synthesis of trilobatin from naringin via prunin as the key intermediate: Acidic hydrolysis of the α-rhamnosidic linkage in naringin under improved conditions

  Kurahayashi, K., Hanaya, K., Higashibayashi, S. & Sugai, T., 2018, In: Bioscience, Biotechnology and Biochemistry. 82, 9, p. 1463-1467 5 p.

  研究成果: Article › 査読

  • trilobatin 100%
  • prunin 90%
  • naringin 66%
  • Naringin 62%
  • Hydrolysis 40%
  6 被引用数 (Scopus)

• Synthesis of various water-soluble C₆₀ derivatives and their superoxide-quenching activity

  Okuda, K., Hirota, T., Hirobe, M., Nagano, T., Mochizuki, M. & Mashino, T., 2000 1月 1, In: Fullerene Science and Technology. 8, 3, p. 127-142 16 p.

  研究成果: Article › 査読

  • inorganic peroxides 100%
  • fullerenes 72%
  • Fullerenes 72%
  • Quenching 71%
  • Fullerene 63%
  29 被引用数 (Scopus)

• Synthesis of water-soluble C₆₀-porphyrin hybrid compounds

  Okuda, K., Abeta, C., Hirota, T., Mochizuki, M. & Mashino, T., 2002 7月, In: Chemical and Pharmaceutical Bulletin. 50, 7, p. 985-987 3 p.

  研究成果: Article › 査読

  • C60-porphyrin 100%
  • Water Soluble 31%
  • Pharmaceutical 29%
  • Water 27%
  • Pharmaceutical Preparations 16%
  8 被引用数 (Scopus)

• Synthetic studies on the thiostrepton family of peptide antibiotics: Synthesis of the tetrasubstituted dehydropiperidine and piperidine cores

  Higashibayashi, S., Hashimoto, K. & Nakata, M., 2002 1月 1, In: Tetrahedron Letters. 43, 1, p. 105-110 6 p.

  研究成果: Article › 査読

  • azomethine 100%
  • Thiostrepton 86%
  • Imines 74%
  • piperidine 71%
  • Azomethine Ylide 63%
  28 被引用数 (Scopus)

• Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the pentapeptide segment containing dihydroxyisoleucine, thiazoline and dehydroamino acid

  Higashibayashi, S., Kohno, M., Goto, T., Suzuki, K., Mori, T., Hashimoto, K. & Nakata, M., 2004 5月 3, In: Tetrahedron Letters. 45, 19, p. 3707-3712 6 p.

  研究成果: Article › 査読

  • Phenylselenylation 100%
  • Thiostrepton 87%
  • Dehydroamino Acid 79%
  • Lactones 65%
  • Pentapeptide 61%
  34 被引用数 (Scopus)

• Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the tetrasubstituted dihydroquinoline portion of siomycin D₁

  Higashibayashi, S., Mori, T., Shinko, K., Hashimoto, K. & Nakata, M., 2002 1月 1, In: Heterocycles. 57, 1, p. 111-122 12 p.

  研究成果: Article › 査読

  • 5,6,7,8-tetrahydroquinoline 100%
  • Jacobsen Asymmetric Epoxidation 90%
  • Thiostrepton 73%
  • Aromatic Substitution 57%
  • Polypeptide Antibiotic Agent 46%
  25 被引用数 (Scopus)

• Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the cyclic core portion containing the dehydropiperidine, dihydroquinoline, L-valine, and masked dehydroalanine segments

  Mori, T., Tohmiya, H., Satouchi, Y., Higashibayashi, S., Hashimoto, K. & Nakata, M., 2005 9月 19, In: Tetrahedron Letters. 46, 38, p. 6423-6427 5 p.

  研究成果: Article › 査読

  • dehydroalanine 100%
  • Thiostrepton 88%
  • L-Valine 69%
  • Valine 60%
  • Polypeptide Antibiotic Agent 56%
  16 被引用数 (Scopus)

• Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the dihydroquinoline portion of thiostrepton, the siomycins, and the thiopeptins

  Mori, T., Satouchi, Y., Tohmiya, H., Higashibayashi, S., Hashimoto, K. & Nakata, M., 2005 9月 19, In: Tetrahedron Letters. 46, 38, p. 6417-6422 6 p.

  研究成果: Article › 査読

  • thiopeptin 100%
  • siomycin 99%
  • Thiostrepton 77%
  • Polypeptide Antibiotic Agent 49%
  • triethylamine 35%
  13 被引用数 (Scopus)

• TAK1 promotes cell survival by TNFAIP3 and IL-8 dependent and NF-kB independent pathway in HeLa cells exposed to heat stress

  Li, P., Furusawa, Y., Wei, Z. L., Sakurai, H., Tabuchi, Y., Zhao, Q. L., Saiki, I. & Kondo, T., 2013, In: International Journal of Hyperthermia. 29, 7, p. 688-695 8 p.

  研究成果: Article › 査読

  • Heat-Shock Response 100%
  • NF-kappa B 96%
  • HeLa Cells 90%
  • Interleukin-8 86%
  • Cell Survival 68%
  4 被引用数 (Scopus)

• Tapping the translation potential of cAMP signalling: Molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR

  Boulton, S., Akimoto, M., VanSchouwen, B., Moleschi, K., Selvaratnam, R., Giri, R. & Melacini, G., 2014 4月, In: Biochemical Society Transactions. 42, 2, p. 302-307 6 p.

  研究成果: Article › 査読

  • Ion Channel Gating 100%
  • Cyclic AMP Receptors 88%
  • Cyclic Nucleotides 70%
  • Guanine 69%
  • Cyclic AMP-Dependent Protein Kinases 60%
  14 被引用数 (Scopus)

• Technetium-99m complexes with steroid-2-aminooxyethyliminodiacetic acid conjugates

  Yoda, R., Karube, Y., Takata, J., Nagata, Y. & Matsushima, Y., 1999 3月, In: Chemical and Pharmaceutical Bulletin. 47, 3, p. 413-416 4 p.

  研究成果: Article › 査読

  Open Access

  • Epiandrosterone 100%
  • Estrone 71%
  • Progesterone 68%
  • Technetium 68%
  • Testosterone 68%
  3 被引用数 (Scopus)

• Temperature-modulated antibody drug separation using thermoresponsive mixed polymer brush-modified stationary phase

  Nagase, K., Ishii, S., Takeuchi, A. & Kanazawa, H., 2022 10月 15, In: Separation and Purification Technology. 299, 121750.

  研究成果: Article › 査読

  • Antibodies 100%
  • Polymer Brush 93%
  • Brushes 93%
  • Poly(4-Vinylpyridine) 60%
  • Polymers 57%
  3 被引用数 (Scopus)

• Temperature-modulated cell-separation column using temperature-responsive cationic copolymer hydrogel-modified silica beads

  Nagase, K., Inanaga, D., Ichikawa, D., Mizutani Akimoto, A., Hattori, Y. & Kanazawa, H., 2019 6月 1, In: Colloids and Surfaces B: Biointerfaces. 178, p. 253-262 10 p.

  研究成果: Article › 査読

  • Hydrogels 100%
  • Copolymers 91%
  • Cell Separation 91%
  • Silicon Dioxide 87%
  • Silica 79%
  22 被引用数 (Scopus)

• Temperature-responsive chromatographic separation of amino acid phenylthiohydantoins using aqueous media as the mobile phase

  Kanazawa, H., Sunamoto, T., Matsushima, Y., Kikuchi, A. & Okano, T., 2000 12月 15, In: Analytical chemistry. 72, 24, p. 5961-5966 6 p.

  研究成果: Article › 査読

  • Amino acids 100%
  • Temperature 33%
  • Acid 29%
  • Functional polymers 28%
  • Surface 26%
  147 被引用数 (Scopus)

• Temperature-responsive chromatography

  Kanazawa, H., Matsushima, Y. & Okano, T., 1998 8月, In: TrAC - Trends in Analytical Chemistry. 17, 7, p. 435-440 6 p.

  研究成果: Article › 査読

  • Poly(N-Isopropylacrylamide) Polymer 100%
  • Chromatography 49%
  • Column Like Crystal 38%
  • Surface 20%
  56 被引用数 (Scopus)

• Temperature responsive chromatography for therapeutic drug monitoring with an aqueous mobile phase

  Nagase, K., Nishiyama, T., Inoue, M. & Kanazawa, H., 2021 12月, In: Scientific reports. 11, 1, 23508.

  研究成果: Article › 査読

  Open Access

  • Chromatography 100%
  • Drug 67%
  • Column Like Crystal 25%
  • Hydrogel 22%
  • Organic Solvent 21%
  6 被引用数 (Scopus)

• Temperature-responsive chromatography using a functional polymer modified stationary phase with molecular recognition sites

  Sakata, K., Ohkubo, K., Hiruta, Y., Ayano, E. & Kanazawa, H., 2014 7月, In: KOBUNSHI RONBUNSHU. 71, 7, p. 293-301 9 p.

  研究成果: Article › 査読

  • Molecular recognition 100%
  • Functional polymers 98%
  • Chromatography 79%
  • chromatography 60%
  • Molecular Recognition 58%
  4 被引用数 (Scopus)

• Temperature-responsive chromatography using poly(N-isopropylacrylamide)-modified silica

  Kanazawa, H., Yamamoto, K., Matsushima, Y., Takai, N., Kikuchi, A., Sakurai, Y. & Okano, T., 1996 12月 1, In: Analytical chemistry. 68, 1, p. 100-105 6 p.

  研究成果: Article › 査読

  • Chromatography 100%
  • Silica 75%
  • Steroid 54%
  • High performance liquid chromatography 50%
  • High-Pressure Liquid Chromatography 44%
  408 被引用数 (Scopus)

• Temperature-responsive fluorescence polymer probes with accurate thermally controlled cellular uptakes

  Hiruta, Y., Shimamura, M., Matsuura, M., Maekawa, Y., Funatsu, T., Suzuki, Y., Ayano, E., Okano, T. & Kanazawa, H., 2014 3月 18, In: ACS Macro Letters. 3, 3, p. 281-285 5 p.

  研究成果: Article › 査読

  • Fluorescence 100%
  • Critical Solution Temperature 96%
  • Polymers 63%
  • Probe 53%
  • Copolymers 41%
  67 被引用数 (Scopus)

• Temperature-Responsive Liquid Chromatography. 2. Effects of Hydrophobic Groups in N-Isopropylacrylamide Copolymer-Modified Silica

  Kanazawa, H., Kashiwase, Y., Yamamoto, K., Matsushima, Y., Kikuchi, A., Sakurai, Y. & Okano, T., 1997 12月 1, In: Analytical chemistry. 69, 5, p. 823-830 8 p.

  研究成果: Article › 査読

  • Liquid chromatography 100%
  • Copolymers 77%
  • Silica 67%
  • Methacrylate 48%
  • Liquid Chromatography 47%
  228 被引用数 (Scopus)

• Temperature-responsive mixed-mode column containing temperature-responsive polymer-modified beads and anionic polymer-modified beads

  Nagase, K., Watanabe, M., Zen, F. & Kanazawa, H., 2019 11月 4, In: Analytica Chimica Acta. 1079, p. 220-229 10 p.

  研究成果: Article › 査読

  • poly-N-isopropylacrylamide 100%
  • Polymers 54%
  • polymer 47%
  • Temperature 44%
  • Column Like Crystal 36%
  19 被引用数 (Scopus)

• Temperature-responsive mixed-mode column for the modulation of multiple interactions

  Nagase, K., Matsumoto, K. & Kanazawa, H., 2022 12月, In: Scientific reports. 12, 1, 4434.

  研究成果: Article › 査読

  Open Access

  • poly-N-isopropylacrylamide 100%
  • poly(3-acrylamidopropyl)trimethylammonium chloride 95%
  • Silicon Dioxide 69%
  • Temperature 44%
  • Static Electricity 36%
  3 被引用数 (Scopus)

• Temperature-responsive molecular recognition chromatography using phenylalanine and tryptophan derived polymer modified silica beads

  Hiruta, Y., Kanazashi, R., Ayano, E., Okano, T. & Kanazawa, H., 2016 2月 7, In: Analyst. 141, 3, p. 910-917 8 p.

  研究成果: Article › 査読

  Open Access

  • Molecular recognition 100%
  • N-isopropylacrylamide 89%
  • Chromatography 79%
  • Aromatic Amino Acid 68%
  • Silicon Dioxide 66%
  29 被引用数 (Scopus)

• Temperature-responsive polymers for liquid-phase separations

  Kanazawa, H., 2004 1月 1, In: Analytical and bioanalytical chemistry. 378, 1, p. 46-48 3 p.

  研究成果: Article › 査読

  • poly-N-isopropylacrylamide 100%
  • Acrylamide 57%
  • Polymers 54%
  • Temperature 44%
  • acrylic acid 29%
  33 被引用数 (Scopus)

• Temperature-responsive solid-phase extraction column for biological sample pretreatment

  Akimaru, M., Okubo, K., Hiruta, Y. & Kanazawa, H., 2015, In: analytical sciences. 31, 9, p. 881-886 6 p.

  研究成果: Article › 査読

  Open Access

  • Extraction Column 100%
  • Phenytoin 36%
  • Theophylline 32%
  • Drug 28%
  • Eluent 26%
  19 被引用数 (Scopus)